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F. Sônego · SciRah

Researcher profile · Semantic Scholar

F. Sônego

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F. Sônego — researcher profile on SciRah

h-index: 20
Works: 62
Citations: 2,257

Most-cited papers

Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection
J. Alves-Filho, F. Sônego, F. O. Souto, A. Freitas +7 more
2010Nature Medicine486 citations
Semantic Scholar
Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis
P. G. Czaikoski, J. S. Mota, D. Nascimento, F. Sônego +10 more
2016PLoS ONE360 citations Open access
Semantic Scholar
Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation.
C. Silva, C. Wanderley, F. Veras, F. Sônego +23 more
2021Blood246 citations Open access
Semantic Scholar
Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious
F. Sônego, Fernanda V. S. Castanheira, R. Ferreira, A. Kanashiro +6 more
2016Frontiers in Immunology210 citations Open access
Semantic Scholar
Regulation of type 17 helper T-cell function by nitric oxide during inflammation
W. Niedbała, J. Alves-Filho, S. Fukada, S. Vieira +6 more
2011Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
The pattern recognition receptors Nod1 and Nod2 account for neutrophil recruitment to the lungs of mice infected with Legionella pneumophila.
M. S. Frutuoso, J. Hori, Marcelo S. F. Pereira, D. S. L. Junior +5 more
2010Microbes and infection108 citations Open access
Semantic Scholar
Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis
D. Nascimento, J. Alves-Filho, F. Sônego, S. Fukada +5 more
2010Critical Care Medicine91 citations
Semantic Scholar
PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis
A. Ferreira, F. Sisti, F. Sônego, Suojang Wang +7 more
2014Journal of Immunology80 citations Open access
Semantic Scholar
IL-17 Receptor Signaling Is Required to Control Polymicrobial Sepsis 1
A. Freitas, J. Alves-Filho, Tatiana Victoni, T. Sécher +4 more
200971 citations
Semantic Scholar
Nitric oxide enhances Th9 cell differentiation and airway inflammation
W. Niedbała, A. Besnard, D. Nascimento, Paula B. Donate +10 more
2014Nature Communications69 citations Open access
Semantic Scholar
Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis
A. Kanashiro, F. Sônego, R. Ferreira, Fernanda V. S. Castanheira +7 more
2016Pharmacological Research59 citations Open access
Semantic Scholar
Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation
T. Cunha, Jhimmy Talbot, L. G. Pinto, S. Vieira +7 more
2010Molecular Pain50 citations Open access
Semantic Scholar
The aggravation of arthritis by periodontitis is dependent of IL‐17 receptor A activation
S. D. de Aquino, Jhimmy Talbot, F. Sônego, W. Turato +4 more
2017Journal of Clinical Periodontology41 citations
Semantic Scholar
Toll-like receptor 9 activation in neutrophils impairs chemotaxis and reduces sepsis outcome*
S. Trevelin, J. Alves-Filho, F. Sônego, W. Turato +5 more
2012Critical Care Medicine34 citations
Semantic Scholar
Bi-specific autoantigen-T cell engagers as targeted immunotherapy for autoreactive B cell depletion in autoimmune diseases
Luca Perico, F. Casiraghi, F. Sônego, M. Todeschini +9 more
2024Frontiers in Immunology33 citations Open access
Semantic Scholar
Targeting neutrophils in sepsis
F. Sônego, J. Alves-Filho, F. Cunha
2014Expert Review of Clinical Immunology33 citations
Semantic Scholar
Metalloproteinase inhibition protects against cardiomyocyte injury during experimental acute pulmonary thromboembolism*
Evandro M. Neto-Neves, C. Dias-Junior, E. Rizzi, M. Castro +3 more
2011Critical Care Medicine32 citations
Semantic Scholar
CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis.
Fernanda V. S. Castanheira, K. A. de Lima, G. C. Cebinelli, F. Sônego +9 more
2019Shock23 citations Open access
Semantic Scholar
The Atypical Chemokine Receptor ACKR2 is Protective Against Sepsis
Fernanda V. S. Castanheira, Vanessa F. Borges, F. Sônego, A. Kanashiro +12 more
2017Shock20 citations Open access
Semantic Scholar
Heme Oxygenase Inhibition Enhances Neutrophil Migration Into the Bronchoalveolar Spaces and Improves the Outcome of Murine Pneumonia-Induced Sepsis
P. G. Czaikoski, D. Nascimento, F. Sônego, Andressa C. de Freitas +12 more
2013Shock20 citations
Semantic Scholar
Rhinoscleroma pathogenesis: The type K3 capsule of Klebsiella rhinoscleromatis is a virulence factor not involved in Mikulicz cells formation
Barbara Corelli, Ana S. Almeida, F. Sônego, Virginia Castiglia +4 more
2018PLoS Neglected Tropical Diseases19 citations Open access
Semantic Scholar
MyD88-, but Not Nod1- and/or Nod2-Deficient Mice, Show Increased Susceptibility to Polymicrobial Sepsis due to Impaired Local Inflammatory Response
F. Sônego, Fernanda V. S. Castanheira, P. G. Czaikoski, A. Kanashiro +9 more
2014PLoS ONE15 citations Open access
Semantic Scholar
Divergent Role OF Heme Oxygenase Inhibition in the Pathogenesis of Sepsis
A. Freitas, J. Alves-Filho, S. Trevelin, F. Spiller +9 more
2011Shock15 citations Open access
Semantic Scholar
Two birds with one stone: human SIRPα nanobodies for functional modulation and in vivo imaging of myeloid cells
Teresa R. Wagner, S. Blaess, Inga B. Leske, D. I. Frecot +18 more
2023bioRxiv12 citations Open access
Semantic Scholar
Imaging of Red-Shifted Light From Bioluminescent Tumors Using Fluorescence by Unbound Excitation From Luminescence
F. Sônego, S. Bouccara, T. Pons, N. Lequeux +5 more
2019Frontiers in Bioengineering and Biotechnology5 citations Open access
Semantic Scholar
The host control of a clinical isolate strain of P. aeruginosa infection is independent of Nod-1 but depends on MyD88
F. Sônego, Fernanda V. S. Castanheira, Catarina V. Horta, A. Kanashiro +4 more
2018Inflammation Research5 citations
Semantic Scholar
Tumor-dependent myeloid and lymphoid cell recruitment in genO-BRGSF-HIS mice: a novel tool for evaluating immunotherapies
Gaelle H. Martin, Siham Hedir, Florent Creusat, A. Gonon +11 more
2025Frontiers in Immunology2 citations Open access
Semantic Scholar
877 Assessment of γδ T cell therapies in humanized mice
Gaelle H. Martin, A. Gonon, F. Sônego, Yacine Chérifi +1 more
2024Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
Abstract 4139: Functional human myeloid cells in BRGSF-HIS humanized mice enables myeloid-directed therapy assessment
Florence Renart-depontieu, G. Martin, V. Moine, Coline Burnet-Merlin +7 more
2023Cancer Research2 citations
Semantic Scholar
Abstract 5635: Enhanced anti-tumor lymphocyte function and frequencies measured by multichromatic flow cytometry in human CTLA-4 knock-in mice in a colorectal carcinoma model after treatment with ipilimumab
E. Reap, F. Sônego, Emily G. O’Koren, Martin Gaëlle +8 more
2020Immunology2 citations
Semantic Scholar
Abstract LB-063: Validation of humanized PD-1 knock-in mice as an emerging model to evaluate human specific PD-1 therapeutics
A. Avrutskaya, F. Sônego, Jacob Hauser, Emily G. O’Koren +8 more
2019Immunology2 citations
Semantic Scholar
Abstract 2045: Novel TFRC humanized mouse model for drug delivery to the brain
F. Sônego, Angela Pappalardo, Gaelle H. Martin, B. Ozgür +5 more
2024Cancer Research1 citations
Semantic Scholar
Abstract 5292: CD28 humanized mouse model for efficacy and safety assessment of CD28-targeting therapies
F. Sônego, Angela Pappalardo, Gaelle H. Martin, Yacine Chérifi +2 more
2024Cancer Research1 citations
Semantic Scholar
Abstract 4036: BRGSF-HIS and CD3Ε humanized mice: Translatable preclinical mouse models for assessment of T-cell engagers-induced CRS
P. Martin-Jeantet, Florence Renart-depontieu, L. Bourré, G. Martin +6 more
2022Cancer Research1 citations
Semantic Scholar
14 Novel CD3 epsilon humanized N-terminal epitope model for assessment of efficacy of T-cell engagers
G. Martin, F. Sônego, A. Beringer, Chloé Beuraud +4 more
2020Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
Imaging of red-shifted photons from bioluminescent tumours using fluorescence by unbound excitation from luminescence
F. Sônego, S. Bouccara, T. Pons, N. Lequeux +5 more
2018bioRxiv1 citations Open access
Semantic Scholar
Guanylate cyclase inhibition by methylene blue in circulatory shock caused by acute necrotizing pancreatitis: a word of caution based on a porcine model.
C. Baldo, V. Capellini, A. Celotto, F. Sônego +5 more
2013Revista do Colégio Brasileiro de Cirurgiões1 citations
Semantic Scholar
Abstract 5244: Functional γδ T cells in humanized mice
Florent Creusat, Siham Hedir, A. Gonon, Amélie Marguier +4 more
2025Cancer Research0 citations
Semantic Scholar
443 Efficacy and safety assessment of CCR8-targeting agents in preclinical humanized models
F. Sônego, Angela Pappalardo, Gaelle H. Martin, Yacine Chérifi +2 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract 3126: Tumor microenvironment composition is shaped by tumor cell line-derived xenograft subtype and tumor burden in BRGSF-HIS mice
Florent Creusat, Siham Hedir, A. Gonon, Amélie Marguier +4 more
2025Cancer Research0 citations
Semantic Scholar
Abstract 7273: CCR8/CCL1 humanized model for efficacy assessment of CCR8/CCL1-targeting therapies
F. Sônego, Angela Pappalardo, Gaelle H. Martin, Yacine Chérifi +2 more
2025Cancer Research0 citations
Semantic Scholar
812 NK cell recruitment into A549 TME in genO-BRGSF-HIS mice
Siham Hedir, Florent Creusat, Amélie Marguier, Yacine Chérifi +3 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Characterization of human lung immune cells in the humanized BRGSF mouse model.
D. Pokhreal, Anna V. Curioni, Florent Creusat, Gaelle H. Martin +8 more
2025Journal of Immunology0 citations
Semantic Scholar
A double humanized mouse model of immune checkpoint blockade to study immune-related adverse events due to cancer immunotherapy 3957
Mousa Vatanmakanian, Priyanka Saminathan, Mahati Rayadurgam, Ian Mathews +8 more
2025Journal of Immunology0 citations
Semantic Scholar
Abstract 3230: Preclinical double humanized CD47/SIRPΑ mouse model and MC38 cell line expressing human CD47 for efficacy and safety assessment of anti-CD47/SIRPΑ-targeting therapies
P. De La Rochere, Angela Pappalardo, Gaelle H. Martin, Yacine Chérifi +3 more
2025Cancer Research0 citations
Semantic Scholar
835 γδ T cells are functional and recruited into the TME in genO-BRGSF-HIS mice
Florent Creusat, Siham Hedir, A. Gonon, Amélie Marguier +4 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
1446 Novel FcγR humanized mouse models enabling efficacy and PK/PD of therapeutic antibodies
F. Sônego, Angela Pappalardo, Gaelle H. Martin, Yacine Chérifi +2 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract 1530: Tumor cell line-derived xenograft subtype shapes tumor microenvironment composition in BRGSF-HIS mice
P. Martin-Jeantet, Siham Hedir, F. Sônego, Gaelle H. Martin +2 more
2024Cancer Research0 citations
Semantic Scholar
Abstract 5341: Novel FcγR humanized mouse model enables assessment of PK/PD of therapeutic antibodies
F. Sônego, Angela Pappalardo, Gaelle H. Martin, R. Courtois +5 more
2024Cancer Research0 citations
Semantic Scholar
937 Tumor microenvironment composition is shaped by tumor cell line-derived xenograft subtype and tumor burden in BRGSF-HIS mice
Gaelle H. Martin, Siham Hedir, P. Martin-Jeantet, F. Sônego +2 more
2024Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar

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F. Cunha×18
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F. Cunha — researcher profile on SciRah
Yacine Chérifi×18
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Yacine Chérifi — researcher profile on SciRah
J. Alves-Filho×16
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J. Alves-Filho — researcher profile on SciRah
Gaelle H. Martin×16
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Gaelle H. Martin — researcher profile on SciRah

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Kader Thiam — researcher profile on SciRah

D. Nascimento×11

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Patricia Isnard-Petit×8

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Fernanda V. S. Castanheira×7

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Fernanda V. S. Castanheira — researcher profile on SciRah

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Siham Hedir — researcher profile on SciRah

Florent Creusat×7

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Florent Creusat — researcher profile on SciRah

Angela Pappalardo×7

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Angela Pappalardo — researcher profile on SciRah

P. G. Czaikoski×6

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P. G. Czaikoski — researcher profile on SciRah