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T. Sécher · SciRah

Researcher profile · Semantic Scholar

T. Sécher

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T. Sécher — researcher profile on SciRah

h-index: 32
Works: 97
Citations: 3,615

Most-cited papers

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.
A. Couturier-Maillard, T. Sécher, A. Rehman, S. Normand +15 more
2013Journal of Clinical Investigation542 citations Open access
Semantic Scholar
Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation
Kevin N. Couper, T. Barnes, J. Hafalla, V. Combes +5 more
2010PLoS Pathogens237 citations Open access
Semantic Scholar
Dominant-Negative Inhibitors of Soluble TNF Attenuate Experimental Arthritis without Suppressing Innate Immunity to Infection
J. Zalevsky, T. Sécher, S. Ezhevsky, Laure Janot +9 more
2007Journal of Immunology157 citations
Semantic Scholar
Genotoxicity of Escherichia coli Nissle 1917 strain cannot be dissociated from its probiotic activity
M. Olier, I. Marcq, Christel Salvador‐Cartier, T. Sécher +8 more
2012Gut microbes146 citations Open access
Semantic Scholar
Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction
T. Sécher, S. Kassem, M. Benamar, I. Bernard +4 more
2017Frontiers in Immunology129 citations Open access
Semantic Scholar
European neuropsychopharmacology: The journal of the European College of Neuropsychopharmacology
J. F. Deakin, D. Nutt, W. Rutz, Z. Rihmer +56 more
2009128 citations
Semantic Scholar
Toll‐like receptor and tumour necrosis factor dependent endotoxin‐induced acute lung injury
D. Togbe, S. Schnyder-Candrian, B. Schnyder, Emilie Doz +11 more
2007International journal of experimental pathology (Print)125 citations Open access
Semantic Scholar
Escherichia coli Producing Colibactin Triggers Premature and Transmissible Senescence in Mammalian Cells
T. Sécher, Ascel Samba-Louaka, É. Oswald, J. Nougayrède
2013PLoS ONE121 citations Open access
Semantic Scholar
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation
K. Aden, A. Rehman, M. Falk-Paulsen, T. Sécher +21 more
2016Cell Reports98 citations Open access
Semantic Scholar
Deciphering the interplay between the genotoxic and probiotic activities of Escherichia coli Nissle 1917
C. Massip, Priscilla Branchu, Nadège Bossuet-Greif, Camille V. Chagneau +7 more
2019PLoS Pathogens97 citations Open access
Semantic Scholar
Blood pressure and glucose independent renoprotective effects of dipeptidyl peptidase-4 inhibition in a mouse model of type-2 diabetic nephropathy
Y. Sharkovska, C. Reichetzeder, Markus L. Alter, O. Tsuprykov +4 more
2014Journal of Hypertension93 citations
Semantic Scholar
Molecular Cloning of a Functional Allatostatin Gut/Brain Receptor and an Allatostatin Preprohormone from the Silkworm Bombyx mori *
T. Sécher, C. Lenz, Giuseppe Cazzamali, G. Sørensen +4 more
2001Journal of Biological Chemistry84 citations Open access
Semantic Scholar
IL-33 targeting attenuates intestinal mucositis and enhances effective tumour chemotherapy in mice
R. Guabiraba, AG Besnard, GB Menezes, T. Sécher +10 more
2014Mucosal Immunology81 citations Open access
Semantic Scholar
Maternally acquired genotoxic Escherichia coli alters offspring’s intestinal homeostasis
D. Payros, T. Sécher, M. Boury, C. Bréhin +16 more
2014Gut microbes80 citations Open access
Semantic Scholar
The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota
D. Payros, U. Dobrindt, Patricia Martín, T. Sécher +6 more
2017mBio79 citations Open access
Semantic Scholar
Alternative Routes of Administration for Therapeutic Antibodies—State of the Art
A. Pitiot, N. Heuzé-Vourc'h, T. Sécher
2022Antibodies71 citations Open access
Semantic Scholar
Local and remote tissue injury upon intestinal ischemia and reperfusion depends on the TLR/MyD88 signaling pathway
Tatiana Victoni, F. Coelho, A. L. Soares, Andressa C. de Freitas +10 more
2010Medical Microbiology and Immmunology71 citations
Semantic Scholar
IL-17 Receptor Signaling Is Required to Control Polymicrobial Sepsis 1
A. Freitas, J. Alves-Filho, Tatiana Victoni, T. Sécher +4 more
200971 citations
Semantic Scholar
CD14 works with toll-like receptor 2 to contribute to recognition and control of Listeria monocytogenes infection.
Laure Janot, T. Sécher, David Torres, I. Maillet +5 more
2008Journal of Infectious Diseases67 citations
Semantic Scholar
Radioresistant cells expressing TLR5 control the respiratory epithelium's innate immune responses to flagellin
Laure Janot, J. Sirard, T. Sécher, N. Noulin +7 more
2009European Journal of Immunology66 citations Open access
Semantic Scholar
Glucagon-Like Peptide-1 Receptor Agonists Increase Pancreatic Mass by Induction of Protein Synthesis
J. Koehler, L. Baggio, Xie-Min Cao, Tahmid Abdulla +5 more
2014Diabetes60 citations Open access
Semantic Scholar
Early settlers: which E. coli strains do you not want at birth?
T. Sécher, C. Bréhin, É. Oswald
2016American Journal of Physiology - Gastrointestinal and Liver Physiology57 citations Open access
Semantic Scholar
Enhancement of Methacholine-Evoked Tracheal Contraction Induced by Bacterial Lipopolysaccharides Depends on Epithelium and Tumor Necrosis Factor
T. Sécher, F. Coelho, N. Noulin, A. Lino dos Santos Franco +10 more
2012Journal of Allergy54 citations Open access
Semantic Scholar
Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis1
T. Sécher, V. Vasseur, D. Poisson, J. Mitchell +3 more
2009Journal of Immunology51 citations Open access
Semantic Scholar
Kidney fibroblast growth factor 23 does not contribute to elevation of its circulating levels in uremia.
M. Mace, E. Gravesen, A. Nordholm, J. Hofman-Bang +3 more
2017Kidney International47 citations Open access
Semantic Scholar
Differential expression of parvalbumin in neonatal phencyclidine‐treated rats and socially isolated rats
Sanne S. Kaalund, J. Riise, Brian Villumsen Broberg, K. Fabricius +4 more
2013Journal of Neurochemistry46 citations
Semantic Scholar
The Anti-Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropenic Mice and Has Additive Effects with Meropenem
T. Sécher, S. Fas, L. Fauconnier, Marieke Mathieu +3 more
2013PLoS ONE44 citations Open access
Semantic Scholar
The endogenous preproglucagon system is not essential for gut growth homeostasis in mice
Pernille Wismann, P. Barkholt, T. Sécher, N. Vrang +7 more
2017Molecular Metabolism37 citations Open access
Semantic Scholar
Oral Tolerance Failure upon Neonatal Gut Colonization with Escherichia coli Producing the Genotoxin Colibactin
T. Sécher, D. Payros, C. Bréhin, M. Boury +8 more
2015Infection and Immunity36 citations Open access
Semantic Scholar
Therapeutic antibodies – natural and pathological barriers and strategies to overcome them
Y. Al Ojaimi, Timothée Blin, J. Lamamy, Matthieu Gracia +9 more
2021Pharmacology and Therapeutics34 citations Open access
Semantic Scholar
Insights on animal models to investigate inhalation therapy: Relevance for biotherapeutics.
A. Guillon, T. Sécher, L. Dailey, L. Vecellio +5 more
2018International journal of pharmaceutics33 citations Open access
Semantic Scholar
Aggregates Associated with Instability of Antibodies during Aerosolization Induce Adverse Immunological Effects
T. Sécher, E. Bodier-Montagutelli, C. Parent, L. Bouvart +7 more
2022Pharmaceutics32 citations Open access
Semantic Scholar
Therapeutic antibodies: A new era in the treatment of respiratory diseases?
T. Sécher, L. Guilleminault, K. Reckamp, I. Amanam +2 more
2018Pharmacology and Therapeutics32 citations
Semantic Scholar
Correlation and clinical relevance of animal models for inhaled pharmaceuticals and biopharmaceuticals.
T. Sécher, E. Bodier-Montagutelli, A. Guillon, N. Heuzé-Vourc'h
2020Advanced Drug Delivery Reviews31 citations Open access
Semantic Scholar
Effect of an NCAM mimetic peptide FGL on impairment in spatial learning and memory after neonatal phencyclidine treatment in rats.
T. Sécher, V. Berezin, E. Bock, B. Glenthøj
2009Behavioural Brain Research31 citations
Semantic Scholar
Nephroprotective Effects of Semaglutide as Mono- and Combination Treatment with Lisinopril in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease
L. S. Dalbøge, Michaelb . Christensen, M. Madsen, T. Sécher +7 more
2022Biomedicines29 citations Open access
Semantic Scholar
Inhalation of Immuno-Therapeutics/-Prophylactics to Fight Respiratory Tract Infections: An Appropriate Drug at the Right Place!
T. Sécher, Alexie Mayor, N. Heuzé-Vourc'h
2019Frontiers in Immunology29 citations Open access
Semantic Scholar
In a murine model of acute lung infection, airway administration of a therapeutic antibody confers greater protection than parenteral administration.
T. Sécher, Emilie Dalonneau, M. Ferreira, C. Parent +4 more
2019Journal of Controlled Release29 citations Open access
Semantic Scholar
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease.
M. V. Østergaard, T. Sécher, Michael Christensen, C. G. Salinas +7 more
2021AJP - Renal Physiology27 citations
Semantic Scholar
The anti-diabetic effects of GLP-1-gastrin dual agonist ZP3022 in ZDF rats.
J. Skarbaliene, T. Sécher, J. Jelsing, Ansarullah +3 more
2015Peptides27 citations
Semantic Scholar
Blockade of IL-1R signaling diminishes Paneth cell depletion and Toxoplasma gondii induced ileitis in mice.
B. Villeret, L. Brault, A. Couturier-Maillard, P. Robinet +7 more
2013American Journal of Clinical and Experimental Immunology27 citations
Semantic Scholar
MAIT Cells Display a Specific Response to Type 1 IFN Underlying the Adjuvant Effect of TLR7/8 Ligands
M Tomislav Pavlovic, Christelle Gross, Chahinaize Chili, T. Sécher +1 more
2020Frontiers in Immunology26 citations Open access
Semantic Scholar
The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice
T. Sécher, I. Maillet, Claire Mackowiak, J. Le Bérichel +10 more
2018Scientific Reports26 citations Open access
Semantic Scholar
Automated Image Analyses of Glomerular Hypertrophy in a Mouse Model of Diabetic Nephropathy.
M. V. Østergaard, Frederikke E. Sembach, J. L. Skytte, U. Roostalu +6 more
2020Kidney36025 citations Open access
Semantic Scholar
DNA Inversion Regulates Outer Membrane Vesicle Production in Bacteroides fragilis
Haruyuki Nakayama-Imaohji, K. Hirota, Hisashi Yamasaki, S. Yoneda +7 more
2016PLoS ONE24 citations Open access
Semantic Scholar
Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice
Frederikke E. Sembach, L. N. Fink, Thea T. Johansen, B. Boland +8 more
2019Physiological Reports23 citations Open access
Semantic Scholar
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure
N. Waldschmitt, Sho Kitamoto, T. Sécher, V. Zacharioudaki +17 more
2018Gut21 citations
Semantic Scholar
Neuromedin U inhibits food intake partly by inhibiting gastric emptying.
L. S. Dalbøge, Søren L. Pedersen, T. Sécher, B. Holst +2 more
2015Peptides20 citations
Semantic Scholar
Phencyclidine treatment increases NR2A and NR2B N-methyl-D-aspartate receptor subunit expression in rats
S. Owczarek, J. Hou, T. Sécher, L. V. Kristiansen
2011NeuroReport12 citations
Semantic Scholar
Soluble NCAM
T. Sécher
2008Neurochemical Research12 citations
Semantic Scholar

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