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L. Cai · SciRah

Researcher profile · Semantic Scholar

L. Cai

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L. Cai — researcher profile on SciRah

h-index: 30
Works: 63
Citations: 2,683

Most-cited papers

Serum Amyloid A Is a Ligand for Scavenger Receptor Class B Type I and Inhibits High Density Lipoprotein Binding and Selective Lipid Uptake*
L. Cai, M. D. de Beer, F. D. de Beer, D. R. van der Westhuyzen
2005Journal of Biological Chemistry180 citations Open access
Semantic Scholar
Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2
Y. Li, L. Cai, H. Wang, P. Wu +8 more
2011Oncogene179 citations Open access
Semantic Scholar
SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance.
L. Cai, A. Ji, F. D. de Beer, Lisa R Tannock +1 more
2008Journal of Clinical Investigation176 citations Open access
Semantic Scholar
Serum Amyloid A Promotes Cholesterol Efflux Mediated by Scavenger Receptor B-I*
D. R. van der Westhuyzen, L. Cai, M. D. de Beer, F. D. de Beer
2005Journal of Biological Chemistry141 citations Open access
Semantic Scholar
High Density Lipoprotein Uptake by Scavenger Receptor SR-BII*
E. Eckhardt, L. Cai, Bing Sun, N. Webb +1 more
2004Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Scavenger Receptor CD36 Expression Contributes to Adipose Tissue Inflammation and Cell Death in Diet-Induced Obesity
L. Cai, Zhen Wang, A. Ji, Jason M. Meyer +1 more
2012PLoS ONE108 citations Open access
Semantic Scholar
Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI.
M. D. de Beer, D. Durbin, L. Cai, A. Jonas +2 more
2001Journal of Lipid Research108 citations
Semantic Scholar
Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis
Ying Chen, H. Hao, Song-Qing He, L. Cai +6 more
2010Molecular Cancer Therapeutics106 citations Open access
Semantic Scholar
The LXR–Idol axis differentially regulates plasma LDL levels in primates and mice
Cynthia Hong, Stephanie M. Marshall, Allison L. Mcdaniel, M. Graham +13 more
2014Cell Metabolism96 citations Open access
Semantic Scholar
Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a
Henry S. Cheng, R. Besla, Angela Li, Zhiqi Chen +17 more
2017Circulation Research91 citations Open access
Semantic Scholar
Small Molecule Inhibition of Gut Microbial Choline Trimethylamine Lyase Activity Alters Host Cholesterol and Bile Acid Metabolism.
P. Pathak, Robert N. Helsley, Amanda L. Brown, J. Buffa +11 more
2020American Journal of Physiology. Heart and Circulatory Physiology83 citations Open access
Semantic Scholar
Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI[S]
A. Ji, J. M. Wroblewski, L. Cai, M. D. de Beer +2 more
2012Journal of Lipid Research79 citations Open access
Semantic Scholar
Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages
L. Cai, Zhen Wang, Jason M. Meyer, A. Ji +1 more
2012Journal of Lipid Research75 citations Open access
Semantic Scholar
Scavenger receptor SR-BI in macrophage lipid metabolism
A. Ji, Jason M. Meyer, L. Cai, Akinwunmi Akinmusire +3 more
2011Atherosclerosis74 citations Open access
Semantic Scholar
Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells
Zhaohui Cai, L. Cai, Jieyun Jiang, Kyung-Soo Chang +2 more
2007Journal of Virology74 citations Open access
Semantic Scholar
Lipoxin A4 and its analog suppress hepatocellular carcinoma via remodeling tumor microenvironment.
H. Hao, Miao Liu, Ping Wu, L. Cai +5 more
2011Cancer Letters73 citations
Semantic Scholar
High Density Lipoprotein Endocytosis by Scavenger Receptor SR-BII Is Clathrin-dependent and Requires a Carboxyl-terminal Dileucine Motif*
E. Eckhardt, L. Cai, Shoba Shetty, Zhenze Zhao +3 more
2006Journal of Biological Chemistry73 citations Open access
Semantic Scholar
XX sex chromosome complement promotes atherosclerosis in mice
Yasir Alsiraj, Xu-Qi Chen, S. Thatcher, Ryan E. Temel +14 more
2019Nature Communications72 citations Open access
Semantic Scholar
Apolipoprotein A-II Modulates the Binding and Selective Lipid Uptake of Reconstituted High Density Lipoprotein by Scavenger Receptor BI*
M. D. de Beer, D. Durbin, L. Cai, Nichole Mirocha +4 more
2001Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Surface engineered polymersomes for enhanced modulation of dendritic cells during cardiovascular immunotherapy
Sijia Yi, Xiaohan Zhang, Hussain Sangji, Yu-Gang Liu +11 more
2019Advanced Functional Materials67 citations Open access
Semantic Scholar
Exosomal miR-199a-5p promotes hepatic lipid accumulation by modulating MST1 expression and fatty acid metabolism
Yu-Han Li, Yansong Luan, Jianning Li, Hui Song +11 more
2020Hepatology International59 citations
Semantic Scholar
Lipoxin A4 Inhibits 5-Lipoxygenase Translocation and Leukotrienes Biosynthesis to Exert a Neuroprotective Effect in Cerebral Ischemia/Reperfusion Injury
Le Wu, Sen Miao, Lin Zou, Ping Wu +8 more
2012Journal of Molecular Neuroscience55 citations
Semantic Scholar
Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration
Sean D. Allen, Yu-Gang Liu, Sharan Bobbala, L. Cai +3 more
2018Nano Reseach52 citations
Semantic Scholar
Macrophage Scavenger Receptor A Mediates Adhesion to Apolipoproteins A-I and E
Claudine Neyen, A. Plüddemann, P. Roversi, Benjamin Thomas +4 more
2009Biochemistry52 citations Open access
Semantic Scholar
Macrophage angiotensin-converting enzyme (ACE) reduces atherosclerosis by increasing PPARα and fundamentally changing lipid metabolism.
Duo-Yao Cao, Zakir Khan, Xiaomo Li, Suguru Saito +14 more
2023Cardiovascular Research49 citations Open access
Semantic Scholar
Low-Density Lipoprotein From Apolipoprotein E–Deficient Mice Induces Macrophage Lipid Accumulation in a CD36 and Scavenger Receptor Class A–Dependent Manner
Zhenze Zhao, M. D. de Beer, L. Cai, R. Asmis +3 more
2004Arteriosclerosis, Thrombosis and Vascular Biology47 citations Open access
Semantic Scholar
Lipoxin A4 ameliorates cerebral ischaemia/reperfusion injury through upregulation of nuclear factor erythroid 2-related factor 2
Le Wu, Ziwei Liu, Sen Miao, Lin Zou +5 more
2013Neurological Research44 citations
Semantic Scholar
The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200173-JLR200
N. Webb, L. Cai, Kristine S. Ziemba, Jin Yu +3 more
2002Journal of Lipid Research38 citations Open access
Semantic Scholar
ApoA-II modulates the association of HDL with class B scavenger receptors SR-BI and CD36 Published, JLR Papers in Press, January 16, 2004. DOI 10.1194/jlr.M300417-JLR200
M. D. de Beer, L. Castellani, L. Cai, A. Stromberg +2 more
2004Journal of Lipid Research34 citations Open access
Semantic Scholar
Formyl-peptide receptor like 1: a potent mediator of the Ca2+ release-activated Ca2+ current ICRAC.
Yong-Sheng Li, Ping Wu, Xiao-Yan Zhou, Jian-Guo Chen +8 more
2008Archives of Biochemistry and Biophysics33 citations
Semantic Scholar
Accumulation and expression of serum amyloid P component in human atherosclerotic lesions
Zhi-Qing Song, L. Cai, Ling Guo, Yoshitane Tsukamoto +2 more
2010Atherosclerosis30 citations Open access
Semantic Scholar
Effect of Lipoxin A4 on Lipopolysaccharide-Induced Endothelial Hyperpermeability
Hua-yan Pang, P. Yi, Ping Wu, Zhuo-Ya Liu +6 more
2011TheScientificWorldJournal26 citations Open access
Semantic Scholar
Renal Angiotensinogen is Predominantly Liver-Derived in Nonhuman Primates
Masayoshi Kukida, L. Cai, Dien Ye, Hisashi Sawada +9 more
2021bioRxiv21 citations Open access
Semantic Scholar
Effects of Lipoxin A4 on CoCl2-Induced Angiogenesis and Its Possible Mechanisms in Human Umbilical Vein Endothelial Cells
Song-jun Liu, Ping Wu, Du-Yun Ye, Yinping Huang +3 more
2009Pharmacology18 citations
Semantic Scholar
Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development
Seonwook Kim, Lihua Yang, Seongu Kim, Richard G. Lee +7 more
2017PLoS ONE13 citations Open access
Semantic Scholar
Minimally oxidized LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell formation[S]
Jason M. Meyer, A. Ji, L. Cai, D. R. van der Westhuyzen
2014Journal of Lipid Research13 citations Open access
Semantic Scholar
Pleiotropic regulation of macrophage polarization and tumorigenesis by formyl peptide receptor-2
Y. Li, L. Cai, H. Wang, P. Wu +8 more
2011Oncogene12 citations Open access
Semantic Scholar
Scavenger receptor BI, not LDL receptor, mediates adrenal stress response
Misa A. Ito, Xiang Ye, Qian Wang, Ling Guo +6 more
2020Arteriosclerosis, Thrombosis and Vascular Biology10 citations Open access
Semantic Scholar
Dietary and Pharmacologic Manipulations of Host Lipids and Their Interaction With the Gut Microbiome in Non-human Primates
Jennifer M. Lang, Leslie R. Sedgeman, L. Cai, Joseph D. Layne +5 more
2021Frontiers in Medicine9 citations Open access
Semantic Scholar
Antisense oligonucleotides targeting hepatic angiotensinogen reduce atherosclerosis and liver steatosis in hypercholesterolemic mice
Dien Ye, Congqing Wu, L. Cai, Deborah A. Howatt +7 more
2023Global translational medicine8 citations Open access
Semantic Scholar
A small deletion in SERPINC1 causes type I antithrombin deficiency by promoting endoplasmic reticulum stress
Jing-Jing Su, L. Shu, Zhou-Ji Zhang, L. Cai +3 more
2016OncoTarget6 citations Open access
Semantic Scholar
Association of NOTCH3 with Elastic Fiber Dispersion in the Infrarenal Abdominal Aorta of Cynomolgus Monkeys
S. Ito, N. Amioka, Michael K. Franklin, Pengjun Wang +7 more
2023bioRxiv5 citations Open access
Semantic Scholar
[Effect of lipoxin A(4) on lipopolysaccharide-induced endothelial hyperpermeability in human umbilical vein endothelial cell].
Hua-yan Pang, Yinping Huang, Zhong-jie Liu, P. Yi +8 more
2011Zhonghua fu chan ke za zhi5 citations
Semantic Scholar
[Protective effects and its mechanism of lipoxins on human umbilical vein endothelial cells under hypoxia].
Song-jun Liu, Yong-Sheng Li, Xiao-Yan Zhou, L. Cai +4 more
2009Zhonghua fu chan ke za zhi2 citations
Semantic Scholar
HDL Uptake by Scavenger Receptor SR-BII
E. Eckhardt, L. Cai, Bing Sun, N. Webb +1 more
20042 citations
Semantic Scholar
Lipotoxicity induced pancreatic beta cell damage is associated with GPR119/MST1/FoxO1 Pathway
Li-Rong Ma, Jianning Li, Huipeng Song, Yan Li +6 more
20211 citations Open access
Semantic Scholar
Impact of MicroRNA-33a/b Antagonism on Atherosclerosis Regression and Stabilization in a Nonhuman Primate Model
L. Cai, Peter I. Hecker, Tong Li, Joseph D. Layne +13 more
2018Atherosclerosis Supplements1 citations
Semantic Scholar
[The stimulation of human pulmonary artery endothelial cells by cigarette smoke extract contributed to cell senescence and induced human pulmonary artery smooth cell migration].
L. Cai, P.-C. Zhu, Y.-E. Wang, Yt Gao +1 more
2017Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases1 citations
Semantic Scholar
ANTISENSE OLIGONUCLEOTIDES TARGETING HEPATIC ANGIOTENSINOGEN DOSE-DEPENDENTLY REDUCE ATHEROSCLEROSIS AND LIVER STEATOSIS IN HYPERCHOLESTEROLEMIC MICE
Dien Ye, Congqing Wu, L. Cai, Deborah A. Howatt +6 more
2022Journal of Hypertension0 citations Open access
Semantic Scholar
Renal Angiotensinogen in Nonhuman Primates is Predominantly Liver-Derived
Masayoshi Kukida, L. Cai, Dien Ye, Hisashi Sawada +9 more
20210 citations
Semantic Scholar

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