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Hiroyasu Ito · SciRah

Researcher profile · Semantic Scholar

Hiroyasu Ito

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Hiroyasu Ito — researcher profile on SciRah

h-index: 34
Works: 175
Citations: 3,087

Most-cited papers

Sonographic Evaluation of the Peripheral Nerve in Diabetic Patients
Tsuneo Watanabe, Hiroyasu Ito, Ayako Sekine, Yuriko Katano +5 more
2010Journal of ultrasound in medicine150 citations Open access
Semantic Scholar
Serum exosomal P-glycoprotein is a potential marker to diagnose docetaxel resistance and select a taxoid for patients with prostate cancer.
Taku Kato, K. Mizutani, Koji Kameyama, Kyojiro Kawakami +8 more
2015Urologic oncology115 citations
Semantic Scholar
The Absence of IDO Upregulates Type I IFN Production, Resulting in Suppression of Viral Replication in the Retrovirus-Infected Mouse
Masato Hoshi, Kuniaki Saito, A. Hara, Ayako Taguchi +8 more
2010Journal of Immunology84 citations Open access
Semantic Scholar
Indoleamine 2,3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP
Soranobu Ninomiya, T. Hara, H. Tsurumi, Masato Hoshi +12 more
2011Annals of Hematology83 citations Open access
Semantic Scholar
Sonographic Evaluation of the Median Nerve in Diabetic Patients
Tsuneo Watanabe, Hiroyasu Ito, Ayako Morita, Yuriko Uno +6 more
2009Journal of ultrasound in medicine82 citations
Semantic Scholar
l-Tryptophan-mediated Enhancement of Susceptibility to Nonalcoholic Fatty Liver Disease Is Dependent on the Mammalian Target of Rapamycin
Y. Osawa, H. Kanamori, E. Seki, Masato Hoshi +8 more
2011Journal of Biological Chemistry80 citations Open access
Semantic Scholar
Serum concentration of L‐kynurenine predicts the clinical outcome of patients with diffuse large B‐cell lymphoma treated with R‐CHOP
T. Yoshikawa, T. Hara, H. Tsurumi, N. Goto +10 more
2010European Journal of Haematology73 citations
Semantic Scholar
Indoleamine 2,3-dioxygenase is highly expressed in human adult T-cell leukemia/lymphoma and chemotherapy changes tryptophan catabolism in serum and reduced activity.
Masato Hoshi, Hiroyasu Ito, H. Fujigaki, M. Takemura +6 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis60 citations
Semantic Scholar
Effects of Indoleamine 2,3-Dioxygenase Deficiency on High-Fat Diet-Induced Hepatic Inflammation
J. Nagano, M. Shimizu, T. Hara, Y. Shirakami +9 more
2013PLoS ONE59 citations Open access
Semantic Scholar
Activation of NLRP3 signalling accelerates skin wound healing
Hiroyasu Ito, A. Kanbe, Hiroyasu Sakai, M. Seishima
2018Experimental Dermatology58 citations
Semantic Scholar
l-Tryptophan–Kynurenine Pathway Metabolites Regulate Type I IFNs of Acute Viral Myocarditis in Mice
Masato Hoshi, K. Matsumoto, Hiroyasu Ito, H. Ohtaki +7 more
2012Journal of Immunology55 citations
Semantic Scholar
Ability of IDO To Attenuate Liver Injury in α-Galactosylceramide–Induced Hepatitis Model
Hiroyasu Ito, Masato Hoshi, H. Ohtaki, Ayako Taguchi +7 more
2010Journal of Immunology53 citations Open access
Semantic Scholar
Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression
Y. Osawa, E. Seki, Yuzo Kodama, A. Suetsugu +10 more
2011The FASEB Journal52 citations Open access
Semantic Scholar
IFN-γ Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model
H. Kanoh, A. Ishitsuka, Etsuko Fujine, Shuhei Matsuhaba +5 more
2019Journal of Immunological Research50 citations Open access
Semantic Scholar
(-)-Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells.
Kengo Ogawa, T. Hara, M. Shimizu, J. Nagano +7 more
2012Oncology Letters49 citations Open access
Semantic Scholar
Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance.
Hiroyasu Ito, K. Ando, T. Ishikawa, T. Nakayama +7 more
2008International Immunology49 citations
Semantic Scholar
Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice
M. Takamatsu, A. Hirata, H. Ohtaki, Masato Hoshi +8 more
2015Cancer Science46 citations Open access
Semantic Scholar
Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice
Y. Osawa, E. Seki, M. Adachi, A. Suetsugu +4 more
2010Hepatology46 citations Open access
Semantic Scholar
Suppression of azoxymethane‐induced colonic preneoplastic lesions in rats by 1‐methyltryptophan, an inhibitor of indoleamine 2,3‐dioxygenase
Kengo Ogawa, T. Hara, M. Shimizu, Soranobu Ninomiya +9 more
2012Cancer Science44 citations Open access
Semantic Scholar
High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia
Ryoko Mabuchi, T. Hara, Takuro Matsumoto, Y. Shibata +11 more
2016Leukemia and Lymphoma41 citations Open access
Semantic Scholar
Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics
K. Fukuno, T. Hara, H. Tsurumi, Y. Shibata +7 more
2015Leukemia and Lymphoma41 citations Open access
Semantic Scholar
Blockade of Indoleamine 2,3-Dioxygenase Reduces Mortality from Peritonitis and Sepsis in Mice by Regulating Functions of CD11b+ Peritoneal Cells
Masato Hoshi, Y. Osawa, Hiroyasu Ito, H. Ohtaki +5 more
2014Infection and Immunity38 citations Open access
Semantic Scholar
Systemic and topical administration of spermidine accelerates skin wound healing
D. Ito, Hiroyasu Ito, T. Ideta, A. Kanbe +2 more
2020Cell Communication and Signaling37 citations Open access
Semantic Scholar
Regulation of the Induction and Function of Cytotoxic T Lymphocytes by Natural Killer T Cell
Hiroyasu Ito, M. Seishima
2010Journal of Biomedicine and Biotechnology37 citations Open access
Semantic Scholar
Inhibition of indoleamine 2,3‐dioxygenase activity enhances the anti‐tumour effects of a Toll‐like receptor 7 agonist in an established cancer model
Hiroyasu Ito, T. Ando, Yuko Arioka, Kuniaki Saito +1 more
2015Immunology36 citations Open access
Semantic Scholar
IL4 from T Follicular Helper Cells Downregulates Antitumor Immunity
H. Shirota, D. Klinman, Shuku-ei A. Ito, Hiroyasu Ito +2 more
2016Cancer immunology research34 citations Open access
Semantic Scholar
Upregulation of indoleamine 2,3‐dioxygenase in hepatocyte during acute hepatitis caused by hepatitis B virus‐specific cytotoxic T lymphocytes in vivo
Naoki Iwamoto, Hiroyasu Ito, K. Ando, T. Ishikawa +7 more
2009Liver international (Print)34 citations
Semantic Scholar
Role of TNF-α Produced by Nonantigen-Specific Cells in a Fulminant Hepatitis Mouse Model
Hiroyasu Ito, K. Ando, T. Ishikawa, Kuniaki Saito +4 more
2009Journal of Immunology32 citations
Semantic Scholar
Inhibition of induced nitric oxide synthase enhances the anti-tumor effects on cancer immunotherapy using TLR7 agonist in mice
Hiroyasu Ito, T. Ando, Hideyuki Ogiso, Yuko Arioka +1 more
2015Cancer Immunology and Immunotherapy30 citations Open access
Semantic Scholar
Comparison of chemiluminescence enzyme immunoassay (CLEIA) with ELISA for the determination of anti-cyclic citrullinated peptide antibodies.
Ryo Tanaka, M. Takemura, Masao Sato, Yasunori Yamada +7 more
2010Clinica chimica acta; international journal of clinical chemistry28 citations
Semantic Scholar
A case of sepsis caused by Streptococcus canis in a dog owner: a first case report of sepsis without dog bite in Japan
H. Ohtaki, K. Ohkusu, H. Ohta, Takashi Miyazaki +6 more
2013Journal of Infection and Chemotherapy26 citations
Semantic Scholar
Induction of humoral and cellular immune response to HBV vaccine can be up-regulated by STING ligand.
Hiroyasu Ito, A. Kanbe, A. Hara, T. Ishikawa
2019Virology25 citations Open access
Semantic Scholar
Activation of STING signaling accelerates skin wound healing.
Yuki Mizutani, A. Kanbe, Hiroyasu Ito, M. Seishima
2019Journal of dermatological science (Amsterdam)25 citations Open access
Semantic Scholar
The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice
Hideyuki Ogiso, Hiroyasu Ito, T. Ando, Yuko Arioka +8 more
2016PLoS ONE25 citations Open access
Semantic Scholar
Induction of hepatitis B virus surface antigen‐specific cytotoxic T lymphocytes can be up‐regulated by the inhibition of indoleamine 2, 3‐dioxygenase activity
Hiroyasu Ito, T. Ando, K. Ando, T. Ishikawa +3 more
2014Immunology25 citations Open access
Semantic Scholar
Quantitative Sonographic Assessment of the Quadriceps Femoris Muscle in Healthy Japanese Adults
Tsuneo Watanabe, H. Murakami, D. Fukuoka, N. Terabayashi +6 more
2017Journal of ultrasound in medicine24 citations Open access
Semantic Scholar
Inhibition of iNOS activity enhances the anti-tumor effects of alpha-galactosylceramide in established murine cancer model
Hiroyasu Ito, T. Ando, M. Seishima
2015OncoTarget24 citations Open access
Semantic Scholar
Toll-like Receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes
T. Ando, Hiroyasu Ito, H. Ohtaki, M. Seishima
2013Scientific Reports24 citations Open access
Semantic Scholar
Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse.
Masato Hoshi, Kuniaki Saito, Yuki Murakami, Ayako Taguchi +6 more
2009Neurosciences research24 citations Open access
Semantic Scholar
Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice
Nobuhiko Nakamura, T. Hara, M. Shimizu, Ryoko Mabuchi +11 more
2015International journal of hematology22 citations
Semantic Scholar
Inhibition of indoleamine 2,3-dioxygenase activity accelerates skin wound healing.
Hiroyasu Ito, T. Ando, Hideyuki Ogiso, Yuko Arioka +2 more
2015Biomaterials22 citations
Semantic Scholar
Immunogenicity of BNT162b2 mRNA COVID-19 Vaccine in Patients with Cardiovascular Disease
Hiroyuki Naruse, Hiroyasu Ito, H. Izawa, M. Sarai +6 more
2021Journal of Clinical Medicine21 citations Open access
Semantic Scholar
The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis
Y. Shibata, T. Hara, J. Nagano, Nobuhiko Nakamura +9 more
2016PLoS ONE21 citations Open access
Semantic Scholar
Usefulness of serum cystatin C to determine the dose of vancomycin in critically ill patients
A. Suzuki, Yoshinori Imanishi, Shiho Nakano, T. Niwa +10 more
2010The Journal of pharmacy and pharmacology21 citations
Semantic Scholar
Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis.
H. Ohtaki, Hiroyasu Ito, K. Ando, T. Ishikawa +7 more
2014Biochimica et Biophysica Acta20 citations Open access
Semantic Scholar
Role of TNF-alpha produced by nonantigen-specific cells in a fulminant hepatitis mouse model.
Hiroyasu Ito, K. Ando, T. Ishikawa, Kuniaki Saito +4 more
2009Journal of Immunology18 citations
Semantic Scholar
A pilot study to assess Fatty infiltration of the supraspinatus in patients with rotator cuff tears: comparison with magnetic resonance imaging.
Tsuneo Watanabe, N. Terabayashi, D. Fukuoka, H. Murakami +3 more
2015Ultrasound in Medicine and Biology16 citations
Semantic Scholar
d-mannose administration improves autoimmune hepatitis by upregulating regulatory T cells.
Daisuke Ito, Hiroyasu Ito, T. Ideta, A. Kanbe +1 more
2022Cellular Immunology15 citations Open access
Semantic Scholar
Evaluation of red blood cell parameters provided by the UF-5000 urine auto-analyzer in patients with glomerulonephritis
Genki Mizuno, Masato Hoshi, K. Nakamoto, Masayo Sakurai +4 more
2021Clinical Chemistry and Laboratory Medicine15 citations
Semantic Scholar
Combination therapy with α-galactosylceramide and a Toll-like receptor agonist exerts an augmented suppressive effect on lung tumor metastasis in a mouse model.
T. Ando, Hiroyasu Ito, Yuko Arioka, Hideyuki Ogiso +1 more
2015Oncology Report15 citations Open access
Semantic Scholar

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M. Seishima×39
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M. Seishima — researcher profile on SciRah
Kuniaki Saito×26
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Kuniaki Saito — researcher profile on SciRah
H. Moriwaki×20
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H. Moriwaki — researcher profile on SciRah
Masato Hoshi×15
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Masato Hoshi — researcher profile on SciRah

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T. Ando — researcher profile on SciRah

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M. Shimizu — researcher profile on SciRah

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H. Ohtaki — researcher profile on SciRah

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M. Takemura — researcher profile on SciRah

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T. Hara — researcher profile on SciRah

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H. Tsurumi — researcher profile on SciRah

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A. Hara — researcher profile on SciRah

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T. Ishikawa — researcher profile on SciRah