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T. Ishikawa · SciRah

Researcher profile · Semantic Scholar

T. Ishikawa

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T. Ishikawa — researcher profile on SciRah

h-index: 34
Works: 157
Citations: 4,270

Most-cited papers

Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice.
Takashi Honda, M. Ishigami, Fangqiong Luo, Lingyun Ma +12 more
2017Metabolism: Clinical and Experimental108 citations
Semantic Scholar
Expression of Toll‐like receptors in chronic hepatitis C virus infection
Ken Sato, T. Ishikawa, A. Okumura, Taeko Yamauchi +7 more
2007Journal of Gastroenterology and Hepatology75 citations
Semantic Scholar
Reduction of liver stiffness by interferon treatment in the patients with chronic hepatitis C
Yuko Arima, Naoto Kawabe, Senju Hashimoto, Masao Harata +11 more
2010Hepatology Research65 citations
Semantic Scholar
Sorafenib vs. Lenvatinib as First-line Therapy for Advanced Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
T. Kuzuya, M. Ishigami, Takanori Ito, Yoji Ishizu +3 more
2020Anticancer Research54 citations Open access
Semantic Scholar
Ability of IDO To Attenuate Liver Injury in α-Galactosylceramide–Induced Hepatitis Model
Hiroyasu Ito, Masato Hoshi, H. Ohtaki, Ayako Taguchi +7 more
2010Journal of Immunology53 citations Open access
Semantic Scholar
Plasma amino acid profiles applied for diagnosis of advanced liver fibrosis in patients with chronic hepatitis C infection.
Qing-Wei Zhang, Mitsuo Takahashi, Yasushi Noguchi, T. Sugimoto +4 more
2006Hepatology Research51 citations
Semantic Scholar
Clinical characteristics and outcomes of candidates for second‐line therapy, including regorafenib and ramucirumab, for advanced hepatocellular carcinoma after sorafenib treatment
T. Kuzuya, M. Ishigami, Takanori Ito, Yoji Ishizu +4 more
2019Hepatology Research50 citations
Semantic Scholar
Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance.
Hiroyasu Ito, K. Ando, T. Ishikawa, T. Nakayama +7 more
2008International Immunology49 citations
Semantic Scholar
Initial Experience of Ramucirumab Treatment After Lenvatinib Failure for Patients With Advanced Hepatocellular Carcinoma
T. Kuzuya, M. Ishigami, Takanori Ito, Yoji Ishizu +3 more
2020Anticancer Research39 citations Open access
Semantic Scholar
Effect of weight change and lifestyle modifications on the development or remission of nonalcoholic fatty liver disease: sex-specific analysis
Naoki Yoshioka, M. Ishigami, Yasuko Watanabe, H. Sumi +9 more
2020Scientific Reports37 citations Open access
Semantic Scholar
Early Clinical Response after 2 Weeks of Sorafenib Therapy Predicts Outcomes and Anti-Tumor Response in Patients with Advanced Hepatocellular Carcinoma
T. Kuzuya, M. Ishigami, Yoji Ishizu, Takashi Honda +6 more
2015PLoS ONE36 citations Open access
Semantic Scholar
Effect of vitamin K2 on the recurrence in patients with hepatocellular carcinoma.
N. Hotta, M. Ayada, Ken Sato, T. Ishikawa +4 more
2007Hepato-Gastroenterology36 citations
Semantic Scholar
Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity
Takanori Ito, M. Ishigami, Yoshihiro Matsushita, Marina Hirata +7 more
2017Scientific Reports35 citations Open access
Semantic Scholar
Liver stiffness in extrahepatic cholestasis correlates positively with bilirubin and negatively with alanine aminotransferase
Masao Harata, Senju Hashimoto, Naoto Kawabe, Yoshifumi Nitta +10 more
2011Hepatology Research35 citations
Semantic Scholar
(-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways.
Hana Satonaka, Kumiki Ishida, Miho Takai, Ryoji Koide +6 more
2017Anticancer Research34 citations Open access
Semantic Scholar
Upregulation of indoleamine 2,3‐dioxygenase in hepatocyte during acute hepatitis caused by hepatitis B virus‐specific cytotoxic T lymphocytes in vivo
Naoki Iwamoto, Hiroyasu Ito, K. Ando, T. Ishikawa +7 more
2009Liver international (Print)34 citations
Semantic Scholar
Deficiency of forkhead box P3 and cytotoxic T‐lymphocyte‐associated antigen‐4 gene expressions and impaired suppressor function of CD4+CD25+ T cells in patients with autoimmune hepatitis
A. Okumura, T. Ishikawa, Sayaka Sato, Taeko Yamauchi +6 more
2008Hepatology Research34 citations
Semantic Scholar
Sarcopenia impairs health-related quality of life in cirrhotic patients.
Yusuke Ando, M. Ishigami, Takanori Ito, Yoji Ishizu +4 more
2019European Journal of Gastroenterology and Hepathology33 citations
Semantic Scholar
Use of the Model for End-Stage Liver Disease (MELD) score to predict 1-year survival of Japanese patients with cirrhosis and to determine who will benefit from living donor liver transplantation
M. Ishigami, Takashi Honda, A. Okumura, T. Ishikawa +5 more
2008Journal of gastroenterology33 citations
Semantic Scholar
Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease
Takanori Ito, M. Ishigami, Yoji Ishizu, T. Kuzuya +5 more
2020European Journal of Gastroenterology and Hepathology32 citations
Semantic Scholar
Favorable radiological antitumor response at 2 weeks after starting lenvatinib for patients with advanced hepatocellular carcinoma
T. Kuzuya, M. Ishigami, Takanori Ito, Yoji Ishizu +3 more
2019Hepatology Research32 citations
Semantic Scholar
Role of TNF-α Produced by Nonantigen-Specific Cells in a Fulminant Hepatitis Mouse Model
Hiroyasu Ito, K. Ando, T. Ishikawa, Kuniaki Saito +4 more
2009Journal of Immunology32 citations
Semantic Scholar
Cumulative incidence and risk factors for the development of hepatocellular carcinoma in patients with chronic hepatitis B who achieved sustained disappearance of viremia by nucleos(t)ide analog treatment
Yusuke Ando, M. Ishigami, Yoji Ishizu, T. Kuzuya +6 more
2018Hepatology Research31 citations Open access
Semantic Scholar
Raloxifene Ameliorates Liver Fibrosis of Nonalcoholic Steatohepatitis Induced by Choline-Deficient High-Fat Diet in Ovariectomized Mice
Fangqiong Luo, M. Ishigami, Koichi Achiwa, Yoji Ishizu +6 more
2015Digestive Diseases and Sciences31 citations Open access
Semantic Scholar
Association of interleukin 28B and mutations in the core and NS5A region of hepatitis C virus with response to peg‐interferon and ribavirin therapy
K. Hayashi, Yoshiaki Katano, Takashi Honda, M. Ishigami +8 more
2011Liver international (Print)31 citations
Semantic Scholar
Differences in background characteristics of patients with chronic hepatitis C who achieved sustained virologic response with interferon‐free versus interferon‐based therapy and the risk of developing hepatocellular carcinoma after eradication of hepatitis C virus in Japan
H. Toyoda, T. Tada, K. Takaguchi, T. Senoh +5 more
2017Journal of Viral Hepatitis29 citations
Semantic Scholar
Clinical characteristics and molecular analysis of hepatitis B virus reactivation in hepatitis B surface antigen-negative patients during or after immunosuppressive or cytotoxic chemotherapy
K. Hayashi, M. Ishigami, Yoji Ishizu, T. Kuzuya +9 more
2016Journal of gastroenterology27 citations
Semantic Scholar
Identification of a novel mutation in the HAMP gene that causes non-detectable hepcidin molecules in a Japanese male patient with juvenile hemochromatosis.
Ai Hattori, N. Tomosugi, Y. Tatsumi, A. Suzuki +7 more
2012Blood Cells, Molecules & Diseases26 citations
Semantic Scholar
Induction of humoral and cellular immune response to HBV vaccine can be up-regulated by STING ligand.
Hiroyasu Ito, A. Kanbe, A. Hara, T. Ishikawa
2019Virology25 citations Open access
Semantic Scholar
The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice
Hideyuki Ogiso, Hiroyasu Ito, T. Ando, Yuko Arioka +8 more
2016PLoS ONE25 citations Open access
Semantic Scholar
Induction of hepatitis B virus surface antigen‐specific cytotoxic T lymphocytes can be up‐regulated by the inhibition of indoleamine 2, 3‐dioxygenase activity
Hiroyasu Ito, T. Ando, K. Ando, T. Ishikawa +3 more
2014Immunology25 citations Open access
Semantic Scholar
A prospective trial of vaccine to prevent hepatitis B virus reactivation after hematopoietic stem cell transplantation
K. Nishikawa, Kiminori Kimura, Y. Kanda, M. Sugiyama +19 more
2020Bone Marrow Transplantation21 citations Open access
Semantic Scholar
Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis.
H. Ohtaki, Hiroyasu Ito, K. Ando, T. Ishikawa +7 more
2014Biochimica et Biophysica Acta20 citations Open access
Semantic Scholar
Prevalence of hepatitis C virus genotype 1a in Japan and correlation of mutations in the NS5A region and single‐nucleotide polymorphism of interleukin‐28B with the response to combination therapy with pegylated‐interferon‐alpha 2b and ribavirin
K. Hayashi, Yoshiaki Katano, T. Kuzuya, Yoshihiko Tachi +11 more
2012Journal of Medical Virology20 citations
Semantic Scholar
Changes in the gut microbiota after hepatitis C virus eradication
Takashi Honda, M. Ishigami, Kenta Yamamoto, Tomoaki Takeyama +9 more
2021Scientific Reports19 citations Open access
Semantic Scholar
Prognostic Factors Associated with Postprogression Survival in Advanced Hepatocellular Carcinoma Patients Treated with Sorafenib Not Eligible for Second-Line Regorafenib Treatment
T. Kuzuya, M. Ishigami, Yoji Ishizu, Takashi Honda +5 more
2018Oncology19 citations
Semantic Scholar
Ursodeoxycholic acid inhibits overexpression of P-glycoprotein induced by doxorubicin in HepG2 cells.
Y. Komori, Sakiko Arisawa, Miho Takai, Kunihiro Yokoyama +8 more
2014European Journal of Pharmacology19 citations
Semantic Scholar
Role of TNF-alpha produced by nonantigen-specific cells in a fulminant hepatitis mouse model.
Hiroyasu Ito, K. Ando, T. Ishikawa, Kuniaki Saito +4 more
2009Journal of Immunology18 citations
Semantic Scholar
Low skeletal muscle mass predicts early mortality in cirrhotic patients with acute variceal bleeding.
Yoji Ishizu, M. Ishigami, T. Kuzuya, Takashi Honda +4 more
2017Nutrition (Burbank, Los Angeles County, Calif.)14 citations
Semantic Scholar
Alteration of serum cytokine balances among different phases of chronic hepatitis B virus infection.
M. Ayada, T. Ishikawa, A. Okumura, Jun-ichi Tanabe +7 more
2006Hepatology Research14 citations
Semantic Scholar
Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
H. Muto, Takanori Ito, Taku Tanaka, S. Yokoyama +14 more
2021Scientific Reports13 citations Open access
Semantic Scholar
Serum Nutritional Markers as Prognostic Factors for Hepatic and Extrahepatic Carcinogenesis in Japanese Patients with Nonalcoholic Fatty Liver Disease
Takanori Ito, M. Ishigami, Yoji Ishizu, T. Kuzuya +5 more
2020Nutrition and Cancer13 citations
Semantic Scholar
The SHAP-hyaluronan complex in serum from patients with chronic liver diseases caused by hepatitis virus infection.
Li Shen, Li-Sheng Zhuo, A. Okumura, T. Ishikawa +8 more
2006Hepatology Research13 citations
Semantic Scholar
Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen
I. Baudi, M. Isogawa, F. Moalli, M. Onishi +10 more
2020bioRxiv12 citations Open access
Semantic Scholar
Coexistence of Copper in the Iron-Rich Particles of Aceruloplasminemia Brain
Kunihiro Yoshida, H. Hayashi, S. Wakusawa, Ryota Shigemasa +6 more
2016Biological Trace Element Research12 citations
Semantic Scholar
Valpha14 NKT cells activated by alpha-galactosylceramide augment lipopolysaccharide-induced nitric oxide production in mouse intra-hepatic lymphocytes.
H. Ohtaki, Hiroyasu Ito, K. Ando, T. Ishikawa +5 more
2009Biochemical and Biophysical Research Communications - BBRC12 citations
Semantic Scholar
Daclatasvir and asunaprevir treatment in patients with severe liver fibrosis by hepatitis C virus genotype 1b infection: Real‐world data
M. Ishigami, K. Hayashi, Takashi Honda, T. Kuzuya +8 more
2017Journal of Gastroenterology and Hepatology11 citations
Semantic Scholar
Fever within 2 Weeks of Sorafenib Therapy Predicts Favorable Treatment Efficacy in Patients with Advanced Hepatocellular Carcinoma
T. Kuzuya, M. Ishigami, Yoji Ishizu, Takashi Honda +5 more
2016Oncology11 citations
Semantic Scholar
IMMUNOREGULATION OF HEPATITIS B VIRUS INFECTION―RATIONALE AND CLINICAL APPLICATION―
T. Ishikawa
2012Nagoya journal of medical science11 citations
Semantic Scholar
Four-dimensional ultrasonography for therapeutic radiofrequency ablation for hepatocellular carcinoma.
N. Hotta, T. Maeno, M. Ayada, Ken Sato +5 more
2006Hepato-Gastroenterology11 citations
Semantic Scholar

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M. Ishigami×24
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M. Ishigami — researcher profile on SciRah
Takashi Honda×22
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Takashi Honda — researcher profile on SciRah
Yoji Ishizu×19
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Yoji Ishizu — researcher profile on SciRah
T. Kuzuya×19
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T. Kuzuya — researcher profile on SciRah

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H. Goto — researcher profile on SciRah

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K. Hayashi — researcher profile on SciRah

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Hiroyasu Ito×12

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Hiroyasu Ito — researcher profile on SciRah

Takanori Ito×11

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Takanori Ito — researcher profile on SciRah

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A. Okumura — researcher profile on SciRah

M. Fujishiro×10

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M. Fujishiro — researcher profile on SciRah

Yoshiaki Katano×9

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Yoshiaki Katano — researcher profile on SciRah