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C. Van den Haute · SciRah

Researcher profile · Semantic Scholar

C. Van den Haute

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C. Van den Haute — researcher profile on SciRah

h-index: 51
Works: 299
Citations: 9,418

Most-cited papers

ATP13A2 deficiency disrupts lysosomal polyamine export
S. van Veen, Shaun Martin, C. Van den Haute, V. Benoy +15 more
2020Nature290 citations Open access
Semantic Scholar
The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies
A. Van der Perren, G. Gelders, Alexis Fenyi, L. Bousset +6 more
2020Acta Neuropathologica226 citations Open access
Semantic Scholar
ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress
S. Vrijsen, Laura Besora-Casals, S. van Veen, Jeffrey Zielich +11 more
2020Proceedings of the National Academy of Sciences of the United States of America96 citations Open access
Semantic Scholar
Regional complexity in enteric neuron wiring reflects diversity of motility patterns in the mouse large intestine
Zhi-Ling Li, Marlene M. Hao, C. Van den Haute, V. Baekelandt +2 more
2019eLife87 citations Open access
Semantic Scholar
BNIP3 promotes HIF‐1α‐driven melanoma growth by curbing intracellular iron homeostasis
Mónica Vara-Pérez, Matteo Rossi, C. Van den Haute, H. Maes +18 more
2021EMBO Journal83 citations Open access
Semantic Scholar
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system
N. Hamouda, C. Van den Haute, Roeland Vanhoutte, Ragna Sannerud +12 more
2020Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
Shaun Martin, S. Smolders, C. Van den Haute, B. Heeman +17 more
2020Acta Neuropathologica67 citations Open access
Semantic Scholar
Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction
W. Heggermont, A. Papageorgiou, A. Quaegebeur, Sophie Deckx +20 more
2017Circulation65 citations Open access
Semantic Scholar
Distinct Mechanisms for Visual and Motor-Related Astrocyte Responses in Mouse Visual Cortex
M. Slezak, S. Kandler, P. Van Veldhoven, C. Van den Haute +2 more
2019Current Biology63 citations Open access
Semantic Scholar
rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.
Dragana Vidovic, M. Carlon, M. D. da Cunha, J. Dekkers +14 more
2016American Journal of Respiratory and Critical Care Medicine61 citations Open access
Semantic Scholar
PERK recruits E-Syt1 at ER–mitochondria contacts for mitochondrial lipid transport and respiration
M. Sassano, A. V. van Vliet, Ellen Vervoort, S. Van Eygen +14 more
2023Journal of Cell Biology59 citations Open access
Semantic Scholar
Structurally defined signaling in neuro‐glia units in the enteric nervous system
W. Boesmans, Marlene M. Hao, C. Fung, Zhi-Ling Li +4 more
2019Glia56 citations Open access
Semantic Scholar
ATP13A2/PARK9 regulates endo‐/lysosomal cargo sorting and proteostasis through a novel PI(3, 5)P2‐mediated scaffolding function
Şeyma Demirsoy, Shaun Martin, S. Motamedi, S. van Veen +6 more
2017Human Molecular Genetics56 citations Open access
Semantic Scholar
Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination
E. Houben, Kris Janssens, Doryssa Hermans, J. Vandooren +11 more
2020Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Long‐term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy
Jana Desloovere, P. Boon, L. Larsen, Caroline Merckx +10 more
2019Epilepsia42 citations Open access
Semantic Scholar
BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states
Francesca Rizzollo, A. Escamilla-Ayala, Nicola Fattorelli, N. Lysiak +19 more
2025Nature Metabolism38 citations Open access
Semantic Scholar
Mutant LRRK2 exacerbates immune response and neurodegeneration in a chronic model of experimental colitis
Diego Cabezudo, George Tsafaras, E. Van Acker, C. Van den Haute +1 more
2023Acta Neuropathologica33 citations Open access
Semantic Scholar
Proximal and distal modulation of neural activity by spatially confined optogenetic activation with an integrated high-density optoelectrode.
S. Libbrecht, L. Hoffman, M. Welkenhuysen, C. Van den Haute +3 more
2018Journal of Neurophysiology32 citations Open access
Semantic Scholar
ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization
Jianmin Si, C. Van den Haute, Evy Lobbestael, Shaun Martin +3 more
2021International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy
M. Goossens, P. Boon, W. Wadman, C. Van den Haute +11 more
2021Epilepsia27 citations Open access
Semantic Scholar
Preclinical evaluation of [18F]MA3: a CB2 receptor agonist radiotracer for PET
B. Attili, Sofie Celen, M. Ahamed, M. Koole +3 more
2018British Journal of Pharmacology24 citations Open access
Semantic Scholar
ATP13A4 Upregulation Drives the Elevated Polyamine Transport System in the Breast Cancer Cell Line MCF7
S. van Veen, A. Kourti, E. Ausloos, J. Van Asselberghs +4 more
2023bioRxiv23 citations Open access
Semantic Scholar
ATP13A3 variants promote pulmonary arterial hypertension by disrupting polyamine transport
Bin Liu, Mujahid Azfar, E. Legchenko, J. West +9 more
2023bioRxiv21 citations Open access
Semantic Scholar
Urinary tract infections trigger synucleinopathy via the innate immune response
W. Peelaerts, Gabriela Mercado, Sonia George, M. Villumsen +23 more
2023Acta Neuropathologica21 citations Open access
Semantic Scholar
Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System
Marine Houdou, N. Jacobs, Jonathan Coene, Mujahid Azfar +6 more
2022bioRxiv21 citations Open access
Semantic Scholar
Optogenetic Stimulation of the Superior Colliculus Confers Retinal Neuroprotection in a Mouse Glaucoma Model
E. Geeraerts, Marie Claes, E. Dekeyster, M. Salinas-Navarro +6 more
2019Journal of Neuroscience20 citations Open access
Semantic Scholar
Evaluation of WGA–Cre-dependent topological transgene expression in the rodent brain
S. Libbrecht, C. Van den Haute, L. Malinouskaya, R. Gijsbers +1 more
2017Brain Structure and Function20 citations Open access
Semantic Scholar
Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus
M. Goossens, L. E. Larsen, Marijke Vergaelen, W. Wadman +10 more
2021eNeuro19 citations Open access
Semantic Scholar
LRRK2 Ablation Attenuates Αlpha-Synuclein–Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo
A. Van der Perren, Diego Cabezudo, G. Gelders, J. M. Peralta Ramos +3 more
2021Neurotherapeutics19 citations Open access
Semantic Scholar
Astrocytes shape the plastic response of adult cortical neurons to vision loss.
Maroussia Hennes, N. Lombaert, Jérôme Wahis, C. Van den Haute +2 more
2020Glia19 citations Open access
Semantic Scholar
Probing the Mechanisms of Repetition Suppression in Inferior Temporal Cortex with Optogenetics.
Francesco Fabbrini, C. Van den Haute, M. De Vitis, V. Baekelandt +2 more
2019Current Biology18 citations Open access
Semantic Scholar
Rab7 reduces α-synuclein toxicity in rats and primary neurons.
E. Szegö, C. Van den Haute, Lennart Höfs, V. Baekelandt +2 more
2021Experimental Neurology17 citations Open access
Semantic Scholar
AAV9-Mediated Overexpression of TRPM4 Increases the Incidence of Stress-Induced Ventricular Arrhythmias in Mice
A. Pironet, Ninda Syam, F. Vandewiele, C. Van den Haute +5 more
2019Frontiers in Physiology17 citations Open access
Semantic Scholar
Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease
D. Chernyuk, M. Callens, M. Polozova, A. Gordeev +8 more
2023IBRO Neuroscience Reports15 citations Open access
Semantic Scholar
Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation.
Matthieu Drouyer, M. Bolliger, Evy Lobbestael, C. Van den Haute +16 more
2021Neurobiology of Disease14 citations Open access
Semantic Scholar
Chronic nigral neuromodulation aggravates behavioral deficits and synaptic changes in an α-synuclein based rat model for Parkinson’s disease
Teresa Torre-Muruzabal, Jens Devoght, C. Van den Haute, B. Brône +2 more
2019Acta Neuropathologica Communications13 citations Open access
Semantic Scholar
Transient and localized optogenetic activation of somatostatin-interneurons in mouse visual cortex abolishes long-term cortical plasticity due to vision loss
Isabelle Scheyltjens, Samme Vreysen, C. Van den Haute, V. Sabanov +3 more
2018Brain Structure and Function13 citations Open access
Semantic Scholar
Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector.
A. Van der Perren, C. Casteels, K. van Laere, R. Gijsbers +2 more
2016Journal of Visualized Experiments13 citations Open access
Semantic Scholar
Label-free imaging of membrane potentials by intramembrane field modulation, assessed by Second Harmonic Generation Microscopy
Y. de Coene, S. Jooken, O. Deschaume, V. Van Steenbergen +8 more
2021bioRxiv12 citations Open access
Semantic Scholar
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma
Mujahid Azfar, Weiman Gao, C. Van den Haute, Lin Xiao +16 more
2025Molecular Oncology11 citations Open access
Semantic Scholar
A Feasibility Study to Investigate Chemogenetic Modulation of the Locus Coeruleus by Means of Single Unit Activity
Latoya Stevens, K. Vonck, L. E. Larsen, Wouter Van Lysebettens +7 more
2020Frontiers in Neuroscience9 citations Open access
Semantic Scholar
Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature
Marie Claes, E. Geeraerts, S. Plaisance, Stephanie Mentens +4 more
2022Cells8 citations Open access
Semantic Scholar
Tissue-Specific Ferritin- and GFP-Based Genetic Vectors Visualize Neurons by MRI in the Intact and Post-Ischemic Rat Brain
M. Khodanovich, A. Akulov, T. Anan’ina, M. Kudabaeva +12 more
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission
S. van Veen, D. Irala, K. Sakers, J. Savage +16 more
2025medRxiv6 citations Open access
Semantic Scholar
The lipid flippase ATP10B enables cellular lipid uptake under stress conditions
Rosanne Wouters, Igor Beletchi, C. Van den Haute, V. Baekelandt +3 more
2023bioRxiv6 citations Open access
Semantic Scholar
Chronic chemogenetic stimulation of the anterior olfactory nucleus reduces newborn neuron survival in the adult mouse olfactory bulb
S. Libbrecht, C. Van den Haute, M. Welkenhuysen, D. Braeken +2 more
2021Journal of Neurochemistry6 citations Open access
Semantic Scholar
Widespread, Specific, and Efficient Transgene Expression in Oligodendrocytes After Intracerebral and Intracerebroventricular Delivery of Viral Vectors in Rodent Brain
W. Peelaerts, Filipa Brito, C. Van den Haute, Anna Barber Janer +3 more
2021Human Gene Therapy5 citations Open access
Semantic Scholar
Fluorescence-free First Hyperpolarizability Values of Fluorescent Proteins and Channel Rhodopsins
E. de Meulenaere, Y. de Coene, I. Russier-Antoine, Louis Vanpraet +7 more
20205 citations Open access
Semantic Scholar
Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formation
T. Vervliet, J. Loncke, M. Sever, K. Ahuja +6 more
2026Nature Communications4 citations Open access
Semantic Scholar
Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy
M. Colijn, S. Vrijsen, P. B. Au, Rania Abou El Asrar +5 more
2024Neurogenetics4 citations Open access
Semantic Scholar

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