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L. Brass · SciRah

Researcher profile · Semantic Scholar

L. Brass

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L. Brass — researcher profile on SciRah

h-index: 71
Works: 222
Citations: 19K

Most-cited papers

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network.
Timothy J. Stalker, Elizabeth A. Traxler, Jie Wu, Kenneth M. Wannemacher +4 more
2013Blood428 citations Open access
Semantic Scholar
A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets.
John D. Welsh, Timothy J. Stalker, Roman S. Voronov, Ryan W. Muthard +3 more
2014Blood198 citations Open access
Semantic Scholar
Regulation of platelet activation and coagulation and its role in vascular injury and arterial thrombosis
Maurizio Tomaiuolo, L. Brass, Timothy J. Stalker
2017Interventional Cardiology Clinics190 citations Open access
Semantic Scholar
Rescuing the physician-scientist workforce: the time for action is now.
D. Milewicz, R. Lorenz, Terence S. Dermody, L. Brass
2015Journal of Clinical Investigation185 citations Open access
Semantic Scholar
Deciphering the human platelet sheddome.
K. Fong, Colin G. Barry, A. Tran, Elizabeth A. Traxler +7 more
2011Blood181 citations Open access
Semantic Scholar
A systems approach to hemostasis: 3. Thrombus consolidation regulates intrathrombus solute transport and local thrombin activity.
Timothy J. Stalker, John D. Welsh, Maurizio Tomaiuolo, Jie Wu +3 more
2014Blood180 citations Open access
Semantic Scholar
Platelet Signaling
Timothy J. Stalker, D. Newman, Peisong Ma, Kenneth M. Wannemacher +1 more
2012Handbook of Experimental Pharmacology154 citations Open access
Semantic Scholar
On-Pump Versus Off-Pump Coronary Artery Bypass Surgery in Elderly Patients: Results From the Danish On-Pump Versus Off-Pump Randomization Study
R. Myerburg, K. Goodman, T. Bruce, I. Ockene +2 more
2012147 citations
Semantic Scholar
Multiscale prediction of patient-specific platelet function under flow.
Matthew H. Flamm, T. Colace, M. Chatterjee, Huiyan Jing +5 more
2012Blood129 citations Open access
Semantic Scholar
Understanding and evaluating platelet function.
L. Brass
2010Hematology. American Society of Hematology. Education Program124 citations
Semantic Scholar
A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment.
Maurizio Tomaiuolo, Timothy J. Stalker, John D. Welsh, S. Diamond +2 more
2014Blood122 citations Open access
Semantic Scholar
P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions
S. Maloney, L. Brass, S. Diamond
2010Integrative Biology100 citations Open access
Semantic Scholar
Transport physics and biorheology in the setting of haemostasis and thrombosis
L. Brass, S. Diamond
2016Journal of Thrombosis and Haemostasis89 citations Open access
Semantic Scholar
Regulating thrombus growth and stability to achieve an optimal response to injury
L. Brass, Kenneth M. Wannemacher, Peisong Ma, Timothy J. Stalker
2011Journal of Thrombosis and Haemostasis85 citations Open access
Semantic Scholar
JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets.
M. Naik, Timothy J. Stalker, L. Brass, U. Naik
2012Blood84 citations Open access
Semantic Scholar
The national MD-PhD program outcomes study: Relationships between medical specialty, training duration, research effort, and career paths.
L. Brass, M. Akabas
2019JCI Insight82 citations Open access
Semantic Scholar
Pairwise Agonist Scanning of human platelets reveals the high-dimensional calcium response to combinatorial mediators of thrombosis
M. Chatterjee, Jeremy E. Purvis, L. Brass, S. Diamond
2010Nature Biotechnology77 citations Open access
Semantic Scholar
Simulation of intrathrombus fluid and solute transport using in vivo clot structures with single platelet resolution
Roman S. Voronov, Timothy J. Stalker, L. Brass, S. Diamond
2013Annals of Biomedical Engineering73 citations Open access
Semantic Scholar
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role
Alec A. Schmaier, Zhi-Ying Zou, Arūnas Kazlauskas, Lori A. Emert-Sedlak +10 more
2009Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Interrelationships between structure and function during the hemostatic response to injury
Maurizio Tomaiuolo, Chelsea N. Matzko, I. Poventud-Fuentes, J. Weisel +2 more
2019Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
Semantic Scholar
Signal Transduction During Platelet Plug Formation
L. Brass, D. Newman, Kenneth M. Wannermacher, Li Zhu +1 more
201368 citations
Semantic Scholar
Shaping the platelet response to vascular injury
Timothy J. Stalker, John D. Welsh, L. Brass
2014Current opinion in hematology66 citations Open access
Semantic Scholar
Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease.
Alec A. Schmaier, Timothy J. Stalker, J. Runge, Dooyoung Lee +10 more
2011Blood65 citations Open access
Semantic Scholar
A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling.
Peisong Ma, A. Cierniewska, Rachel S. Signarvic, M. Cieślak +6 more
2012Blood62 citations Open access
Semantic Scholar
Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.
Yoshiyasu Ueda, Imran Mohammed, Delu Song, D. Gullipalli +14 more
2017Blood61 citations Open access
Semantic Scholar
A systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature.
John D. Welsh, Ryan W. Muthard, Timothy J. Stalker, Joshua P Taliaferro +2 more
2016Blood61 citations Open access
Semantic Scholar
RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury.
Rachel S. Signarvic, A. Cierniewska, Timothy J. Stalker, K. Fong +6 more
2010Blood61 citations Open access
Semantic Scholar
Differential dynamics of platelet contact and spreading.
Dooyoung Lee, K. Fong, M. King, L. Brass +1 more
2012Biophysical Journal60 citations Open access
Semantic Scholar
Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis
Li Zhu, Timothy J. Stalker, K. Fong, Hong Jiang +10 more
2009Arteriosclerosis, Thrombosis and Vascular Biology60 citations Open access
Semantic Scholar
Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation
Shuchi Gupta, Christoph Konradt, Adam Corken, J. Ware +7 more
2020Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.
Ronghua Meng, Jie Wu, Dawn C. Harper, Yuhuan Wang +6 more
2015Blood50 citations Open access
Semantic Scholar
Training the physician-scientist: views from program directors and aspiring young investigators.
Christopher S. Williams, A. Iness, R. Baron, O. Ajijola +13 more
2018JCI Insight44 citations Open access
Semantic Scholar
The national MD-PhD program outcomes study: Outcomes variation by sex, race, and ethnicity.
M. Akabas, L. Brass
2019JCI Insight43 citations Open access
Semantic Scholar
Platelets and hemostasis: a new perspective on an old subject.
L. Brass, S. Diamond, Timothy J. Stalker
2016Blood Advances38 citations Open access
Semantic Scholar
Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.
Kenneth M. Wannemacher, Li Zhu, Hong Jiang, K. Fong +10 more
2010Blood37 citations Open access
Semantic Scholar
Identification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in platelets.
P. Mou, Z. Zeng, Qiang Li, Xiaohui Liu +6 more
2013Blood36 citations Open access
Semantic Scholar
Platelet packing density is an independent regulator of the hemostatic response to injury
Mehran Mirramezani, Bradley A. Herbig, Timothy J. Stalker, Leonard Nettey +7 more
2018Journal of Thrombosis and Haemostasis35 citations Open access
Semantic Scholar
Coordination of platelet agonist signaling during the hemostatic response in vivo.
Jian Shen, Sara Sampietro, Jie Wu, Juan Tang +7 more
2017Blood Advances35 citations Open access
Semantic Scholar
Fibrin, γ’-fibrinogen, and trans-clot pressure gradient control hemostatic clot growth during human blood flow over a collagen/tissue factor wound
Ryan W. Muthard, John D. Welsh, L. Brass, S. Diamond
2015Arteriosclerosis, Thrombosis and Vascular Biology31 citations Open access
Semantic Scholar
The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis
B. Branchford, Timothy J. Stalker, Luke Law, Gilbert Acevedo +17 more
2018Journal of Thrombosis and Haemostasis30 citations Open access
Semantic Scholar
Harnessing the Platelet Signaling Network to Produce an Optimal Hemostatic Response
L. Brass, Maurizio Tomaiuolo, Timothy J. Stalker
2013Hematology/Oncology Clinics of North America30 citations Open access
Semantic Scholar
Increased Levels of Plasma Soluble Sema4D in Patients with Heart Failure
Qiongyu Lu, Ning-Zheng Dong, Qi Wang, Wen-Xiu Yi +9 more
2013PLoS ONE27 citations Open access
Semantic Scholar
Modulating platelet reactivity through control of RGS18 availability.
Peisong Ma, Kristy Ou, Andrew J. Sinnamon, Hong Jiang +2 more
2015Blood26 citations Open access
Semantic Scholar
A Human Vascular Injury-on-a-Chip Model of Hemostasis
I. Poventud-Fuentes, K. Kwon, Jeongyun Seo, Maurizio Tomaiuolo +3 more
2020Small24 citations Open access
Semantic Scholar
Dissociation of SHP-1 from Spinophilin during Platelet Activation Exposes an Inhibitory Binding Site for Protein Phosphatase-1 (PP1)
Peisong Ma, Darci C. Foote, Andrew J. Sinnamon, L. Brass
2015PLoS ONE24 citations Open access
Semantic Scholar
The role of Semaphorins and their receptors in platelets. Lessons learned from neuronal and immune synapses
Kenneth M. Wannemacher, Le Wang, Li Zhu, L. Brass
2011Platelets21 citations Open access
Semantic Scholar
GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets.
Xi Chen, Shuchi Gupta, M. Cooper, Daniel DeHelian +10 more
2019Blood Advances20 citations Open access
Semantic Scholar
Is an MD/PhD program right for me? Advice on becoming a physician–scientist
L. Brass
2018Molecular Biology of the Cell20 citations Open access
Semantic Scholar
Thrombin spatial distribution determines Protein C activation during hemostasis and thrombosis.
T. Marar, Chelsea N. Matzko, Jie Wu, C. Esmon +4 more
2021Blood19 citations Open access
Semantic Scholar
RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival.
Daniel DeHelian, Shuchi Gupta, Jie Wu, Chelsea L. Thorsheim +8 more
2020Blood18 citations Open access
Semantic Scholar

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Timothy J. Stalker×28
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Timothy J. Stalker — researcher profile on SciRah
S. Diamond×17
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Maurizio Tomaiuolo×9
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Maurizio Tomaiuolo — researcher profile on SciRah
Peisong Ma×8
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Peisong Ma — researcher profile on SciRah

Kenneth M. Wannemacher

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Li Zhu — researcher profile on SciRah

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John D. Welsh×6

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K. Fong — researcher profile on SciRah

Shuchi Gupta×5

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Shuchi Gupta — researcher profile on SciRah

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S. Maloney — researcher profile on SciRah