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Adam G. Schrum · SciRah

Researcher profile · Semantic Scholar

Adam G. Schrum

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Adam G. Schrum — researcher profile on SciRah

h-index: 24
Works: 110
Citations: 2,530

Most-cited papers

Mechanism of T-cell tolerance induced by myeloid-derived suppressor cells
S. Nagaraj, Adam G. Schrum, Hyun-Il Cho, E. Celis +1 more
2010Journal of Immunology418 citations Open access
Semantic Scholar
Lifetime incidence risk of Alopecia Areata estimated at 2.1 percent by Rochester Epidemiology Project, 1990–2009
Sultan A. Mirzoyev, Adam G. Schrum, M. Davis, R. Torgerson
2013Journal of Investigative Dermatology325 citations Open access
Semantic Scholar
Different T Cell Receptor Signals Determine CD8+ Memory Versus Effector Development
E. Teixeiro, M. Daniels, Sara E. Hamilton, Adam G. Schrum +3 more
2009Science206 citations
Semantic Scholar
Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies
A. Gilhar, Adam G. Schrum, Amos Etzioni, H. Waldmann +1 more
2016Autoimmunity Reviews116 citations Open access
Semantic Scholar
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
Amber L. Southwell, Stephen E. P. Smith, T. Davis, N. Caron +8 more
2015Scientific Reports89 citations Open access
Semantic Scholar
Strategies to stabilize compact folding and minimize aggregation of antibody-based fragments
Diana Gil, Adam G. Schrum
2013Advances in Bioscience and Biotechnology69 citations Open access
Semantic Scholar
Oral probiotics in coronavirus disease 2019: connecting the gut–lung axis to viral pathogenesis, inflammation, secondary infection and clinical trials
P. Baindara, R. Chakraborty, Zachary M. Holliday, S. Mandal +1 more
2021new microbes and new infections63 citations Open access
Semantic Scholar
Non-Randomized Trial of Dornase Alfa for Acute Respiratory Distress Syndrome Secondary to Covid-19
Zachary M. Holliday, Alexander P. Earhart, Mohammed M Alnijoumi, A. Krvavac +2 more
2021Frontiers in Immunology58 citations Open access
Semantic Scholar
Consideration of dornase alfa for the treatment of severe COVID-19 acute respiratory distress syndrome
Alexander P. Earhart, Zachary M. Holliday, Hunter Hofmann, Adam G. Schrum
2020new microbes and new infections53 citations Open access
Semantic Scholar
B7-H1 Expression on Old CD8+ T Cells Negatively Regulates the Activation of Immune Responses in Aged Animals
Noweeda N. Mirza, M. Duque, A. Dominguez, Adam G. Schrum +2 more
2010Journal of Immunology46 citations Open access
Semantic Scholar
iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata.
Amal Ghraieb, A. Keren, A. Ginzburg, Y. Ullmann +3 more
2018Journal of Autoimmunity45 citations Open access
Semantic Scholar
Multiplex matrix network analysis of protein complexes in the human TCR signalosome
Stephen E. P. Smith, Steven C Neier, Brendan K. Reed, T. Davis +8 more
2016Science Signaling36 citations Open access
Semantic Scholar
IL-12 signals through the TCR to support CD8 innate immune responses
N. Goplen, V. Saxena, K. M. Knudson, Adam G. Schrum +4 more
2016Journal of Immunology35 citations Open access
Semantic Scholar
Combinatorial Immunoprofiling in Latent Tuberculosis Infection. Toward Better Risk Stratification.
P. Escalante, T. Peikert, V. V. Van Keulen, C. Erskine +9 more
2015American Journal of Respiratory and Critical Care Medicine32 citations Open access
Semantic Scholar
Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction.
O. Onyema, Yi-Zhan Guo, B. Mahgoub, Qing Wang +11 more
2019JCI Insight31 citations Open access
Semantic Scholar
Basal and Antigen-Induced Exposure of the Proline-Rich Sequence in CD3ε
J. de la Cruz, Travis Kruger, Christopher A. Parks, Robert L. Silge +4 more
2011Journal of Immunology30 citations Open access
Semantic Scholar
A Role for CD8 in the Developmental Tuning of Antigen Recognition and CD3 Conformational Change1
Diana Gil, Adam G. Schrum, M. Daniels, E. Palmer
2008Journal of Immunology30 citations Open access
Semantic Scholar
Innate lymphoid cells 3 induce psoriasis in xenotransplanted healthy human skin
A. Keren, A. Shemer, A. Ginzburg, Y. Ullmann +3 more
2018Journal of Allergy and Clinical Immunology27 citations
Semantic Scholar
Conservation and Enhanced Binding of SARS-CoV-2 Omicron Spike Protein to Coreceptor Neuropilin-1 Predicted by Docking Analysis
P. Baindara, D. Roy, S. Mandal, Adam G. Schrum
2022Infectious Disease Reports24 citations Open access
Semantic Scholar
Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models
Emily A Brown, Jonathan D. Lautz, T. Davis, Edward P. Gniffke +7 more
2018Molecular Autism24 citations Open access
Semantic Scholar
NOTCH signaling in COVID-19: a central hub controlling genes, proteins, and cells that mediate SARS-CoV-2 entry, the inflammatory response, and lung regeneration
P. Baindara, Md Bodruzzaman Sarker, Alexander P. Earhart, S. Mandal +1 more
2022Frontiers in Cellular and Infection Microbiology20 citations Open access
Semantic Scholar
Chronic respiratory disease disparity between American Indian/Alaska Native and white populations, 2011–2018
Kimberly G. Laffey, A. Nelson, Matthew Laffey, Quynh Nguyen +2 more
2021BMC Public Health20 citations Open access
Semantic Scholar
IP-FCM Measures Physiologic Protein-Protein Interactions Modulated by Signal Transduction and Small-Molecule Drug Inhibition
Stephen E. P. Smith, Anya T. Bida, T. Davis, H. Sicotte +3 more
2012PLoS ONE18 citations Open access
Semantic Scholar
The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network
Steven C Neier, Alejandro Ferrer, K. Wilton, Stephen E. P. Smith +20 more
2019Science immunology16 citations Open access
Semantic Scholar
IgG Fab Fragments Forming Bivalent Complexes by a Conformational Mechanism That Is Reversible by Osmolytes*
A. Nelson, Michele M. Hoffmann, Christopher A. Parks, S. Dasari +2 more
2012Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Multiplex IP-FCM (immunoprecipitation-flow cytometry): Principles and guidelines for assessing physiologic protein-protein interactions in multiprotein complexes
Anya T. Bida, Diana Gil, Adam G. Schrum
2011Methods15 citations Open access
Semantic Scholar
IP-FCM: immunoprecipitation detected by flow cytometry.
T. Davis, Adam G. Schrum
2010Journal of Visualized Experiments15 citations Open access
Semantic Scholar
Visualization of Multiprotein Complexes by Flow Cytometry
Adam G. Schrum
2009Current Protocols in Immunology15 citations Open access
Semantic Scholar
Physical and functional bivalency observed among TCR/CD3 complexes isolated from primary T cells
Adam G. Schrum, Diana Gil, L. Turka, E. Palmer
2011Journal of Immunology14 citations Open access
Semantic Scholar
Quantitative Multiplex co-Immunoprecipitation: Measuring input-specific changes in protein interaction networks at mesoscale.
Emily A Brown, Steven C Neier, C. Neuhauser, Adam G. Schrum +1 more
2019Journal of Visualized Experiments13 citations Open access
Semantic Scholar
Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo
Michele M. Hoffmann, Carlos Molina-Mendiola, A. Nelson, Christopher A. Parks +6 more
2015Science Advances13 citations Open access
Semantic Scholar
Slow angled-descent forepaw grasping (SLAG): an innate behavioral task for identification of individual experimental mice possessing functional vision
Macarena Gil-Pagés, Robert J Stiles, Christopher A. Parks, Steven C Neier +6 more
2013Behavioral and Brain Functions13 citations Open access
Semantic Scholar
A co-housing strategy to improve fecundity of mice in timed matings
Robert J Stiles, Adam G. Schrum, Diana Gil
2013Lab animal11 citations Open access
Semantic Scholar
Vasoactive Intestinal Peptide Amphiphile Micelle Chemical Structure and Hydrophobic Domain Influence Immunomodulatory Potentiation
Xiao-Fei Wang, Rui Zhang, Bryce D. Lindaman, C. Leeper +2 more
2021bioRxiv10 citations Open access
Semantic Scholar
Robustness and Specificity in Signal Transduction via Physiologic Protein Interaction Networks
Adam G. Schrum, Diana Gil
2012Clinical and Experimental Pharmacology10 citations Open access
Semantic Scholar
Lower female survival from an opportunistic infection reveals progesterone-driven sex bias in trained immunity
Alexander P. Earhart, Natalia G. Karasseva, Kathryn M. Storey, B. Olthoff +8 more
2023Cell Reports8 citations Open access
Semantic Scholar
Neutrophils and secondary infections in COVID-19 induced acute respiratory distress syndrome
Zachary M. Holliday, Mohammed M Alnijoumi, Mark A Reed, Alexander P. Earhart +3 more
2021new microbes and new infections8 citations Open access
Semantic Scholar
Signaling protein complexes isolated from primary human skin-resident T cells can be analyzed by Multiplex IP-FCM
Stephen E. P. Smith, Steven C Neier, T. Davis, M. Pittelkow +2 more
2014Experimental Dermatology8 citations Open access
Semantic Scholar
Public and private human T-cell clones respond differentially to HCMV antigen when boosted by CD3 copotentiation.
Laura R. E. Becher, W. Nevala, S. Sutor, Megan Abergel +6 more
2020Blood Advances7 citations Open access
Semantic Scholar
Transcriptional Regulation of the Human IL5RA Gene through Alternative Promoter Usage during Eosinophil Development
Kimberly G. Laffey, Jian Du, Adam G. Schrum, S. Ackerman
2021International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Breaking tolerance with engineered class I antigen-presenting molecules
Christopher A. Parks, Kalli R Henning, K. Pavelko, Michael J. Hansen +9 more
2019Proceedings of the National Academy of Sciences of the United States of America5 citations Open access
Semantic Scholar
A Versatile Simple Capture Assay for Assessing the Structural Integrity of MHC Multimer Reagents
Brendan K. Reed, Laura B. Chopp, Courtney S. Malo, D. Renner +8 more
2015PLoS ONE5 citations Open access
Semantic Scholar
M2e-Derived Peptidyl and Peptide Amphiphile Micelles as Novel Influenza Vaccines
Megan C. Schulte, Agustin T. Barcellona, Xiaofei Wang, Adam G. Schrum +1 more
2024bioRxiv4 citations Open access
Semantic Scholar
A reengineered common chain cytokine augments CD8+ T cell–dependent immunotherapy
A. Banerjee, Dong-Ge Li, Yi-Zhan Guo, Z. Mei +7 more
2022JCI Insight4 citations Open access
Semantic Scholar
A PCR-Based Method to Genotype Mice Knocked Out for All Four CD3 Subunits, the Standard Recipient Strain for Retrogenic TCR/CD3 Bone Marrow Reconstitution Technology
Alejandro Ferrer, Adam G. Schrum, Diana Gil
2013BioResearch Open Access3 citations Open access
Semantic Scholar
Invitation to submit to special collection of papers in MSDE on Molecular Bioengineering: Vasoactive Intestinal Peptide Amphiphile Micelle Material Properties Influence Their Cell Association and Internalization
Xiaofei Wang, Agustin T. Barcellona, Fateme Nowruzi, Kambrie M. Brandt +6 more
2025Molecular Systems Design & Engineering2 citations Open access
Semantic Scholar
Reduced thymic IL-4 impairs negative T cell selection in nonobese diabetic mice
Alexis N. Cattin-Roy, Kimberly G. Laffey, L. Le, Adam G. Schrum +1 more
2024Journal of Clinical Investigation2 citations
Semantic Scholar
Regional Differences in American Indian/Alaska Native Chronic Respiratory Disease Disparity: Evidence from National Survey Results
Kimberly G. Laffey, A. Nelson, Matthew Laffey, Quynh Nguyen +2 more
2024International Journal of Environmental Research and Public Health2 citations Open access
Semantic Scholar
Early expression of mature αβ TCR in CD4−CD8− T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations
Kimberly G. Laffey, Robert J Stiles, Melissa Ludescher, T. Davis +12 more
2022Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
Maternal IL-6 can cause T-cell-mediated juvenile alopecia by non-scarring follicular dystrophy in mice
Stephen E. P. Smith, Rachel L. G. Maus, T. Davis, John P. Sundberg +2 more
2016Experimental Dermatology2 citations Open access
Semantic Scholar

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