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David Q. Shih · SciRah

Researcher profile · Semantic Scholar

David Q. Shih

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David Q. Shih — researcher profile on SciRah

h-index: 45
Works: 226
Citations: 6,673

Most-cited papers

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis
Markus Tschurtschenthaler, Timon E. Adolph, Jonathan W Ashcroft, L. Niederreiter +18 more
2017Journal of Experimental Medicine176 citations Open access
Semantic Scholar
The Impact of Preoperative Serum anti-TNFα Therapy Levels on Early Postoperative Outcomes in Inflammatory Bowel Disease Surgery
C. Lau, M. Dubinsky, G. Melmed, E. Vasiliauskas +6 more
2015Annals of Surgery151 citations Open access
Semantic Scholar
Microbiota-induced TNF-like ligand 1A drives group 3 innate lymphoid cell-mediated barrier protection and intestinal T cell activation during colitis
Jim G. Castellanos, Viola Woo, Monica Viladomiu, G. Putzel +10 more
2018Immunity150 citations Open access
Semantic Scholar
A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation.
David Padua, Swapna Mahurkar-Joshi, I. Law, C. Polytarchou +5 more
2016American Journal of Physiology - Gastrointestinal and Liver Physiology122 citations Open access
Semantic Scholar
Inhibition of a novel fibrogenic factor Tl1a reverses established colonic fibrosis
David Q. Shih, Li-Bo Zheng, Xiao-Lan Zhang, Hong Zhang +7 more
2014Mucosal Immunology98 citations Open access
Semantic Scholar
Inflammation independent TL1A-mediated Intestinal Fibrosis is Dependent on the Gut Microbiome
N. Jacob, J. Jacobs, K. Kumagai, C. W. Ha +11 more
2018Mucosal Immunology92 citations Open access
Semantic Scholar
Myeloid ATG16L1 facilitates host-bacteria interactions in maintaining intestinal homeostasis
Hong Zhang, Li-Bo Zheng, D. McGovern, Ariel M Hamill +10 more
2017Journal of Immunology73 citations Open access
Semantic Scholar
Update 2014: Advances to Optimize 6-Mercaptopurine and Azathioprine to Reduce Toxicity and Improve Efficacy in the Management of IBD
Jaimin Amin, Brian L. Huang, Jessica Yoon, David Q. Shih
2015Inflammatory Bowel Diseases69 citations Open access
Semantic Scholar
Clinical, serologic, and genetic factors associated with pyoderma gangrenosum and erythema nodosum in inflammatory bowel disease patients
A. Weizman, Brian L. Huang, Dror Berel, S. Targan +17 more
2014Inflammatory Bowel Diseases64 citations Open access
Semantic Scholar
Ocular Manifestations in Inflammatory Bowel Disease Are Associated with Other Extra-intestinal Manifestations, Gender, and Genes Implicated in Other Immune-related Traits.
S. Taleban, Dalin Li, S. Targan, A. Ippoliti +12 more
2016Journal of Crohn's & Colitis62 citations Open access
Semantic Scholar
Antibiotics for Treatment of Clostridium difficile Infection in Hospitalized Patients with Inflammatory Bowel Disease
H. Horton, S. Dezfoli, Dror Berel, J. Hirsch +11 more
2014Antimicrobial Agents and Chemotherapy62 citations Open access
Semantic Scholar
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
J. Grootjans, N. Krupka, S. Hosomi, J. D. Matute +27 more
2019Science60 citations Open access
Semantic Scholar
Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease Patients
A. Sideri, Kyriaki Bakirtzi, David Q. Shih, H. Koon +6 more
2015Cellular and Molecular Gastroenterology and Hepatology50 citations Open access
Semantic Scholar
Perianal Crohn’s Disease is associated with distal colonic disease, stricturing disease behavior, IBD-associated serologies and genetic variation in the JAK-STAT pathway
Manreet Kaur, D. Panikkath, Xiao-Fei Yan, Zhen-Qiu Liu +11 more
2016Inflammatory Bowel Diseases46 citations Open access
Semantic Scholar
TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice.
Hui Li, Jia Song, Guo-Chao Niu, Hong Zhang +4 more
2017Pathology, Research and Practice45 citations
Semantic Scholar
Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis
Wen-Xiu Jia, Ming-Yue Yang, Fei Han, Yu-Xin Luo +7 more
2021Mediators of Inflammation42 citations Open access
Semantic Scholar
Gut microbial transcytosis induced by tumor necrosis factor-like 1A-dependent activation of a myosin light chain kinase splice variant contributes to IBD.
Yu-Chen Pai, Liangping Weng, Shu-Chen Wei, Li-Ling Wu +4 more
2020Journal of Crohn's & Colitis41 citations Open access
Semantic Scholar
Effects of obesity on severity of colitis and cytokine expression in mouse mesenteric fat. Potential role of adiponectin receptor 1.
A. Sideri, D. Stavrakis, C. Bowe, David Q. Shih +6 more
2015American Journal of Physiology - Gastrointestinal and Liver Physiology38 citations Open access
Semantic Scholar
Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
N. Jacob, K. Kumagai, Jay P. Abraham, Y. Shimodaira +10 more
2018Scientific Reports36 citations Open access
Semantic Scholar
Insights on the use of biosimilars in the treatment of inflammatory bowel disease
Michael K Zheng, David Q. Shih, Gary C. Chen
2017World Journal of Gastroenterology36 citations Open access
Semantic Scholar
1,25‐dihydroxyvitamin D3 regulates the development of chronic colitis by modulating both T helper (Th)1 and Th17 activation
Hong Zhang, Hui Wu, Lei Liu, Hui Li +2 more
2015Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)32 citations
Semantic Scholar
Pyoderma gangrenosum among patients with inflammatory bowel disease: a descriptive cohort study
A. Weizman, Brian L. Huang, S. Targan, M. Dubinsky +8 more
2014Journal of Cutaneous Medicine and Surgery32 citations
Semantic Scholar
Effects and Mechanism of Constitutive TL1A Expression on Intestinal Mucosal Barrier in DSS-Induced Colitis
Ming-Yue Yang, Wen-Xiu Jia, Dong Wang, Fei Han +4 more
2019Digestive Diseases and Sciences31 citations
Semantic Scholar
Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD
S. Yoon, T. Haritunians, Sultan Chhina, Zhen-Qiu Liu +11 more
2017Inflammatory Bowel Diseases31 citations Open access
Semantic Scholar
Combined Immunosuppression Impairs Immunogenicity to Tetanus and Pertussis Vaccination Among Patients with Inflammatory Bowel Disease
S. Dezfoli, H. Horton, Nattapaun N. Thepyasuwan, Dror Berel +9 more
2015Inflammatory Bowel Diseases30 citations Open access
Semantic Scholar
High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures
Jia-Ni Wang, C. Ortiz, Lindsey Fontenot, Ying Xie +4 more
2019bioRxiv28 citations Open access
Semantic Scholar
Outcomes with Anti-Tumour Necrosis Factor-Alpha Therapy and Serology in Patients with Denovo Crohn’s Disease After Ileal Pouch Anal Anastomosis
L. Robbins, K. Zaghiyan, G. Melmed, E. Vasiliauskas +9 more
2017Journal of Crohn's & Colitis27 citations
Semantic Scholar
The protection role of Atg16l1 in CD11c+ dendritic cells in murine colitis
Hong Zhang, Li-Bo Zheng, Jeremy Chen, M. Fukata +3 more
2017Immunobiology25 citations Open access
Semantic Scholar
Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome
J. Jacobs, M. Goudarzi, V. Lagishetty, Dalin Li +15 more
2022Genome Medicine24 citations Open access
Semantic Scholar
Molecular patterns in human ulcerative colitis and correlation with response to infliximab
B. Halloran, Jessica E. Chang, David Q. Shih, D. McGovern +6 more
2014Inflammatory Bowel Diseases24 citations Open access
Semantic Scholar
Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD
N. Jacob, S. Targan, David Q. Shih
2016United European Gastroenterology journal21 citations Open access
Semantic Scholar
Differential levels of Tl1a affect the expansion and function of regulatory T cells in modulating murine colitis
Maninder Sidhu-Varma, David Q. Shih, S. Targan
2016Inflammatory Bowel Diseases20 citations Open access
Semantic Scholar
TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization
Yu-Xin Luo, Jin-Bo Guo, W. Jia, Mengyao Wu +5 more
2021Oxidative Medicine and Cellular Longevity19 citations Open access
Semantic Scholar
Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine
J. Ruiz, S. Kanagavelu, C. Flores, L. Romero +3 more
2016Frontiers in Cellular and Infection Microbiology19 citations Open access
Semantic Scholar
Pyoderma Gangrenosum among Patients with Inflammatory Bowel Disease: A Descriptive Cohort Study
A. Weizman, Brian L. Huang, S. Targan, M. Dubinsky +8 more
2015Journal of Cutaneous Medicine and Surgery18 citations Open access
Semantic Scholar
Mesenchymal stem cell transplantation improves chronic colitis-associated complications through inhibiting the activity of toll-like receptor-4 in mice
Guo-Chao Niu, Lei Liu, Li-Bo Zheng, Hong Zhang +2 more
2018BMC Gastroenterology17 citations Open access
Semantic Scholar
DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury
Y. Shimodaira, Shyam K. More, Hussein Hamade, Anna Y. Blackwood +11 more
2023Cellular and Molecular Gastroenterology and Hepatology16 citations Open access
Semantic Scholar
Elafin Reverses Intestinal Fibrosis by Inhibiting Cathepsin S-Mediated Protease-Activated Receptor 2
Ying Xie, Lindsey Fontenot, A. C. Estrada, B. Nelson +8 more
2022Cellular and Molecular Gastroenterology and Hepatology16 citations Open access
Semantic Scholar
Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice
Jia-Ni Wang, C. Ortiz, Lindsey Fontenot, Riya Mukhopadhyay +6 more
2020Scientific Reports14 citations Open access
Semantic Scholar
CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway
Chun Xu, Sally Ghali, Jia-Ni Wang, David Q. Shih +12 more
2017Scientific Reports14 citations Open access
Semantic Scholar
Mesenteric Adipose-derived Stromal Cells From Crohn’s Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis
J. Hoffman, A. Sideri, J. J. Ruiz, D. Stavrakis +4 more
2018Cellular and Molecular Gastroenterology and Hepatology13 citations Open access
Semantic Scholar
Title A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS 1 as an enhancer of inflammation
Swapna Mahurkar-Joshi, I. Law, C. Polytarchou, John P. Vu +4 more
201612 citations
Semantic Scholar
Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Primer for Internists.
Gaurav Syal, A. Kashani, David Q. Shih
2018American Journal of Medicine11 citations
Semantic Scholar
Effects and mechanism of adenovirus-mediated phosphatase and tension homologue deleted on chromosome ten gene on collagen deposition in rat liver fibrosis
Shu-Rui Xie, J. An, Li-Bo Zheng, X. Huo +3 more
2017World Journal of Gastroenterology11 citations Open access
Semantic Scholar
TL1A primed dendritic cells activation exacerbated chronic murine colitis.
Fei Han, Jia Song, Wen-Xiu Jia, Ming-Yue Yang +5 more
2020Life Science10 citations
Semantic Scholar
A long noncoding RNA signature for ulcerative colitis identiﬁes IFNG-AS1 as an enhancer of inﬂammation
David Padua, Swapna Mahurkar-Joshi, I. Law, C. Polytarchou +5 more
201610 citations
Semantic Scholar
Sa1965 The Steady-State Pharmacokinetics of Adalimumab: Do We Need to Drink From the “Trough”?
M. Stewart, M. Dubinsky, B. Morganstern, E. Vasiliauskas +6 more
20169 citations
Semantic Scholar
A Multidisciplinary Approach to Biopsychosocial Care for Adults With Inflammatory Bowel Disease: A Pilot Study.
Chang Kyun Lee, G. Melmed, Amy Mann, I. Danovitch +7 more
2018Inflammatory Bowel Diseases8 citations
Semantic Scholar
Serologic, Genetic, and Clinical Associations with Increased Healthcare Resource Utilization in IBD
Phillip Gu, Anshika Kapur, Dalin Li, T. Haritunians +7 more
2018Journal of Digestive Diseases7 citations Open access
Semantic Scholar
Sa1182 Single-Center Experience of Vedolizumab in Patients With Inflammatory Bowel Disease: Does Age Matter?
B. Morganstern, Namita Singh, S. Targan, C. Landers +9 more
20156 citations
Semantic Scholar

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