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Zi-Cheng Hu · SciRah

Researcher profile · Semantic Scholar

Zi-Cheng Hu

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Zi-Cheng Hu — researcher profile on SciRah

h-index: 18
Works: 50
Citations: 5,497

Most-cited papers

xCell: digitally portraying the tissue cellular heterogeneity landscape
D. Aran, Zi-Cheng Hu, A. Butte
2017Genome Biology3,978 citations Open access
Semantic Scholar
ImmPort, toward repurposing of open access immunological assay data for translational and clinical research
S. Bhattacharya, P. Dunn, Cristel G. Thomas, Barry Smith +9 more
2018Scientific Data670 citations Open access
Semantic Scholar
CCR4 promotes medullary entry and thymocyte–dendritic cell interactions required for central tolerance
Zi-Cheng Hu, Jessica N. Lancaster, Chayanit Sasiponganan, Lauren I. R. Ehrlich
2015Journal of Experimental Medicine80 citations Open access
Semantic Scholar
A robust and interpretable end-to-end deep learning model for cytometry data
Zi-Cheng Hu, Alice S. Tang, Jaiveer Singh, Sanchita Bhattacharya +1 more
2020Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Application of Machine Learning for Cytometry Data
Zi-Cheng Hu, Sanchita Bhattacharya, A. Butte
2022Frontiers in Immunology66 citations Open access
Semantic Scholar
Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance
Jessica N. Lancaster, H. M. Thyagarajan, J. Srinivasan, Yong Li +2 more
2019Nature Communications53 citations Open access
Semantic Scholar
MetaCyto: A tool for automated meta-analysis of mass and flow cytometry data
Zi-Cheng Hu, Chethan Jujjavarapu, Jacob J. Hughey, Sandra Andorf +12 more
2018Cell Reports51 citations Open access
Semantic Scholar
MiR-652-3p inhibition enhances endothelial repair and reduces atherosclerosis by promoting Cyclin D2 expression
Rong-Zhong Huang, Zi-Cheng Hu, Yu Cao, Hong-Rong Li +6 more
2019EBioMedicine47 citations Open access
Semantic Scholar
CCR7 modulates the generation of thymic regulatory T cells by altering the composition of the thymic dendritic cell compartment
Zi-Cheng Hu, Y. Li, A. V. van Nieuwenhuijze, Hilary J. Selden +5 more
2017Cell Reports47 citations Open access
Semantic Scholar
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria
Maureen C. Ty, Sheng-Huan Sun, Perri C. Callaway, J. Rek +27 more
2023Science Translational Medicine45 citations Open access
Semantic Scholar
The 10,000 Immunomes Project: Building a Resource for Human Immunology
K. Zalocusky, Matthew J. Kan, Zi-Cheng Hu, P. Dunn +4 more
2018Cell Reports43 citations Open access
Semantic Scholar
Deep phenotyping of Alzheimer’s disease leveraging electronic medical records identifies sex-specific clinical associations
Alice S. Tang, T. Oskotsky, Shreyas Havaldar, W. Mantyh +10 more
2022Nature Communications42 citations Open access
Semantic Scholar
Robust prediction of clinical outcomes using cytometry data
Zi-Cheng Hu, Benjamin S. Glicksberg, A. Butte
2018Bioinform.37 citations Open access
Semantic Scholar
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation
Todd A. Triplett, Kim T. Cardenas, Jessica N. Lancaster, Zi-Cheng Hu +10 more
2016Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus
Zi-Cheng Hu, Jessica N. Lancaster, Lauren I. R. Ehrlich
2015Frontiers in Immunology34 citations Open access
Semantic Scholar
The Transcription Factor SUB1 Is a Master Regulator of the Macrophage TLR Response in Atherosclerosis
Rong-Zhong Huang, Zi-Cheng Hu, Xiao-Rui Chen, Yu Cao +13 more
2021Advancement of science26 citations Open access
Semantic Scholar
Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19
S. Maruthamuthu, Karan Rajalingam, Navchetan Kaur, Maelig G. Morvan +9 more
2022Frontiers in Genetics25 citations Open access
Semantic Scholar
Tumor-associated myeloid cells provide critical support for T-ALL.
Aram Lyu, Todd A. Triplett, S. Nam, Zi-Cheng Hu +9 more
2020Blood21 citations
Semantic Scholar
miR-532-3p-CSF2RA Axis as a Key Regulator of Vulnerable Atherosclerotic Plaque Formation.
Rong-Zhong Huang, Yu Cao, Hong-Rong Li, Zi-Cheng Hu +8 more
2019Canadian Journal of Cardiology18 citations
Semantic Scholar
EBI2 contributes to the induction of thymic central tolerance by promoting rapid motility of medullary thymocytes
Sanghee Ki, H. M. Thyagarajan, Zi-Cheng Hu, Jessica N. Lancaster +1 more
2017European Journal of Immunology16 citations Open access
Semantic Scholar
Early immune markers of clinical, virological, and immunological outcomes in patients with COVID-19: a multi-omics study
Zi-Cheng Hu, K. van der Ploeg, S. Chakraborty, Prabhu S. Arunachalam +23 more
2022eLife15 citations Open access
Semantic Scholar
Comparative effects of lipid lowering, hypoglycemic, antihypertensive and antiplatelet medications on carotid artery intima-media thickness progression: a network meta-analysis
Rong-Zhong Huang, K. Mills, J. Romero, Yan Li +5 more
2019Cardiovascular Diabetology15 citations Open access
Semantic Scholar
Inflammatory cytokines and cells are potential markers for patients with cerebral apoplexy in intensive care unit.
Jian-Hong Wang, Zi-Cheng Hu, Shu Yang, Chengchun Liu +3 more
2018Experimental and Therapeutic Medicine14 citations Open access
Semantic Scholar
Systematic identification of ACE2 expression modulators reveals cardiomyopathy as a risk factor for mortality in COVID-19 patients
Navchetan Kaur, B. Oskotsky, A. Butte, Zi-Cheng Hu
2022American Medical Informatics Association Annual Symposium12 citations Open access
Semantic Scholar
Integrin signaling is critical for myeloid-mediated support of T-cell acute lymphoblastic leukemia
Aram Lyu, Ryan S. Humphrey, S. Nam, T. Durham +4 more
2022bioRxiv11 citations Open access
Semantic Scholar
The Transcription Factor IRF6 Co-Represses PPARγ-Mediated Cytoprotection in Ischemic Cerebrovascular Endothelial Cells
Rong-Zhong Huang, Zi-Cheng Hu, Yuxing Feng, Le-Hua Yu +1 more
2017Scientific Reports9 citations Open access
Semantic Scholar
TRIC-B: an under-explored druggable ion channel
Zi-Cheng Hu, O. Gulyaeva
2019Nature reviews. Drug discovery6 citations
Semantic Scholar
The 10,000 Immunomes Project: A resource for human immunology
K. Zalocusky, Matthew J. Kan, Zi-Cheng Hu, P. Dunn +4 more
2017bioRxiv6 citations Open access
Semantic Scholar
SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 (CLCC1) and triggers an unfolded protein response
Hannah N. Gruner, Yaohuan Zhang, Kaavian Shariati, Nicholas Yiv +6 more
2023PeerJ5 citations Open access
Semantic Scholar
Opportunities and Challenges in Democratizing Immunology Datasets
S. Bhattacharya, Zi-Cheng Hu, A. Butte
2021Frontiers in Immunology5 citations Open access
Semantic Scholar
Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice
A. M. Araujo, Joseph D. Dekker, Kendra C. Garrison, Zhe Su +11 more
2018bioRxiv3 citations Open access
Semantic Scholar
Meta-analysis of Cytometry Data Reveals Racial Differences in Immune Cells
Zi-Cheng Hu, Chethan Jujjavarapu, Jacob J. Hughey, Sandra Andorf +12 more
2017bioRxiv3 citations Open access
Semantic Scholar
Deep clinical phenotyping of Alzheimer's Disease Patients Leveraging Electronic Medical Records Data Identifies Sex-Specific Clinical Associations
Alice S. Tang, T. Oskotsky, W. Mantyh, C. W. Solsberg +5 more
2021medRxiv1 citations Open access
Semantic Scholar
Mining transcriptomics and clinical data reveals ACE2 expression modulators and identifies cardiomyopathy as a risk factor for mortality in COVID-19 patients
Navchetan Kaur, B. Oskotsky, A. Butte, Zi-Cheng Hu
2020medRxiv1 citations Open access
Semantic Scholar
Defining the role of CCR8 in promoting thymocyte development and thymic epithelial homeostasis
H. M. Thyagarajan, Zi-Cheng Hu, Lauren I. R. Ehrlich
2016Journal of Immunology1 citations
Semantic Scholar
CCR4 is required for efficient thymocyte medullary entry and central tolerance induction (HEM7P.230)
Lauren I. R. Ehrlich, Zi-Cheng Hu, Jessica N. Lancaster, Chayanit Sasiponganan
2015Journal of Immunology1 citations
Semantic Scholar
TNFα-Producing CD4 + T Cells Dominate the SARS-CoV-2-Specific T Cell Response in COVID-19 Outpatients and Are Associated with Durable Antibodies
K. van der Ploeg, A. Kirosingh, D. M. Mori, S. Chakraborty +18 more
2022Social Science Research Network0 citations Open access
Semantic Scholar
Identi�cation of conditions associated with gene expression variation using GENEVA
Zi-Cheng Hu
20220 citations
Semantic Scholar
Abstract 3185: Integrin signaling is critical for myeloid-mediated support of T-ALL
Aram Lyu, S. Nam, Zi-Cheng Hu, D. Arasappan +2 more
2021Tumor Biology0 citations
Semantic Scholar
Prevalent mouse phenotypes in the unexplored druggable genome
O. Gulyaeva, Zi-Cheng Hu, Tudor I. Oprea, K. C. Kent Lloyd +3 more
20210 citations Open access
Semantic Scholar
KNa1.1 channels as a target for treating early-onset epilepsy
Zi-Cheng Hu, Hannah N. Gruner, Jana Gagacheva, O. Gulyaeva
2020Nature reviews. Drug discovery0 citations
Semantic Scholar
Efficacy and safety of NAD+ ADP-ribosyltransferase 1 agonist versus Donepezil in elderly Chinese patients with Alzheimer disease: A novel target for effective therapy.
Jian-Hong Wang, Shu Yang, Zi-Cheng Hu, Haimei Yang +3 more
2019Pakistan Journal of Pharmaceutical Sciences0 citations Open access
Semantic Scholar
Common lymphoid progenitor derivation of a conserved dendritic cell subtype is mediated by Bcl11a
Joseph D. Dekker, Catherine Rhee, Zi-Cheng Hu, Bum-Kyu Lee +6 more
2018Journal of Immunology0 citations
Semantic Scholar
EBI2 contributes to central tolerance by promoting rapid motility of medullary thymocytes
H. M. Thyagarajan, Sanghee Ki, Zi-Cheng Hu, Jessica N. Lancaster +1 more
2017Journal of Immunology0 citations
Semantic Scholar
Relative contribution of medullary thymic epithelial cells and dendritic cells to thymocyte central tolerance as assessed by multi-photon microscopy
Lauren I. R. Ehrlich, Jessica N. Lancaster, Zi-Cheng Hu, A. Tran +1 more
2016Journal of Immunology0 citations
Semantic Scholar
The role of CCR4 and CCR7 in the establishment of central tolerance
Zi-Cheng Hu
20160 citations
Semantic Scholar
Detecting calcium flux in T cells using a Bayesian model
Zi-Cheng Hu
20150 citations
Semantic Scholar
Abstract A02: Altered myeloid cells in the tumor microenvironment promote growth of T cell acute lymphoblastic leukemia.
Todd A. Triplett, Kim T. Cardenas, Jessica Jones, Hilary J. Selden +6 more
20150 citations
Semantic Scholar
The cellularity of thymic regulatory T cells is regulated by CCR7 through a non-cell intrinsic mechanism (HEM7P.228)
Zi-Cheng Hu, Lauren I. R. Ehrlich
2015Journal of Immunology0 citations
Semantic Scholar
CCR4-mediated interactions between thymocytes and thymic dendritic cells are required for complete negative selection to self-antigens. (CCR3P.207)
Zi-Cheng Hu, Jessica Jones, Lauren I. R. Ehrlich
2014Journal of Immunology0 citations
Semantic Scholar

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A. Butte×14
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A. Butte — researcher profile on SciRah
Lauren I. R. Ehrlich×14
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Lauren I. R. Ehrlich — researcher profile on SciRah
Jessica N. Lancaster×8
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S. Bhattacharya×5
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Rong-Zhong Huang×5

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H. M. Thyagarajan×4

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Li-Hong Jiang×4

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Hilary J. Selden×4

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B. Oskotsky — researcher profile on SciRah

Lauren I. R. Ehrlich×4

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Lauren I. R. Ehrlich — researcher profile on SciRah

Cristel G. Thomas×3

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Cristel G. Thomas — researcher profile on SciRah