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K. Gottesdiener · SciRah

Researcher profile · Semantic Scholar

K. Gottesdiener

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K. Gottesdiener — researcher profile on SciRah

h-index: 45
Works: 120
Citations: 7,989

Most-cited papers

Induction of Adipocyte Complement-Related Protein of 30 Kilodaltons by PPARγ Agonists: A Potential Mechanism of Insulin Sensitization.
Terry P. Combs, J. Wagner, J. Berger, T. Doebber +14 more
2002Endocrinology549 citations Open access
Semantic Scholar
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
G. Herman, A. Bergman, C. Stevens, P. Kotey +23 more
2006Journal of Clinical Endocrinology and Metabolism525 citations
Semantic Scholar
Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.
P. Kühnen, K. Clément, S. Wiegand, O. Blankenstein +6 more
2016New England Journal of Medicine406 citations
Semantic Scholar
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor
H. Burns, K. van Laere, S. Sanabria-Bohórquez, T. Hamill +25 more
2007Proceedings of the National Academy of Sciences of the United States of America303 citations Open access
Semantic Scholar
Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies.
R. Krishna, Matt S. Anderson, A. Bergman, B. Jin +12 more
2007The Lancet295 citations
Semantic Scholar
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency
K. Clément, H. Biebermann, I. Farooqi, L. van der Ploeg +21 more
2018Nature Medicine276 citations
Semantic Scholar
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization.
Terry P. Combs, J. Wagner, J. Berger, T. Doebber +14 more
2002Endocrinology275 citations
Semantic Scholar
Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.
K. Cheng, Tsuei-ju Wu, Kenneth K. Wu, C. Sturino +7 more
2006Proceedings of the National Academy of Sciences of the United States of America272 citations
Semantic Scholar
Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency
Tinh-Hai Collet, Béatrice Dubern, J. Mokrosiński, Hillori Connors +24 more
2017Molecular Metabolism261 citations Open access
Semantic Scholar
Effect of Sitagliptin, a Dipeptidyl Peptidase‐4 Inhibitor, on Blood Pressure in Nondiabetic Patients With Mild to Moderate Hypertension
G. Mistry, A. Maes, K. Lasseter, M. Davies +3 more
2008Journal of clinical pharmacology218 citations
Semantic Scholar
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.
C. Addy, Hamish Wright, K. van Laere, I. Gantz +30 more
2008Cell Metabolism209 citations Open access
Semantic Scholar
Effects of the neurokinin1 receptor antagonist aprepitant on the pharmacokinetics of dexamethasone and methylprednisolone
J. McCrea, A. Majumdar, M. R. Goldberg, M. Iwamoto +10 more
2003Clinical pharmacology and therapy192 citations
Semantic Scholar
Effect of a 28-d treatment with L-796568, a novel beta(3)-adrenergic receptor agonist, on energy expenditure and body composition in obese men.
T. Larsen, S. Toubro, M. V. van Baak, K. Gottesdiener +3 more
2002American Journal of Clinical Nutrition181 citations Open access
Semantic Scholar
Effect of Rifampin, a Potent Inducer of Drug-Metabolizing Enzymes, on the Pharmacokinetics of Raltegravir
Larissa A. Wenning, W. Hanley, D. Brainard, A. Petry +10 more
2009Antimicrobial Agents and Chemotherapy170 citations Open access
Semantic Scholar
RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.
Kong Y. Chen, R. Muniyappa, Brent S. Abel, Katherine P. Mullins +11 more
2015Journal of Clinical Endocrinology and Metabolism161 citations Open access
Semantic Scholar
Metabolism And Excretion of the Dipeptidyl Peptidase 4 Inhibitor [14C]Sitagliptin in Humans
S. Vincent, J. Reed, A. Bergman, C. Elmore +11 more
2007Drug Metabolism And Disposition153 citations
Semantic Scholar
Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double‐Blind, Randomized, Placebo‐Controlled Phase I Studies
S. Stoch, S. Zajic, J. Stone, Deborah L. Miller +11 more
2009Clinical pharmacology and therapy152 citations
Semantic Scholar
Efficacy and Safety of Relamorelin in Diabetics with Symptoms of Gastroparesis:A Randomized, Placebo-Controlled Study
M. Camilleri, R. McCallum, J. Tack, Sharon Spence +2 more
2017Gastroenterology140 citations Open access
Semantic Scholar
Effect of L-000845704, an αVβ3 integrin antagonist, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women
M. Murphy, K. Cerchio, S. Stoch, K. Gottesdiener +2 more
2005129 citations Open access
Semantic Scholar
Relamorelin Reduces Vomiting Frequency and Severity and Accelerates Gastric Emptying in Adults With Diabetic Gastroparesis.
A. Lembo, M. Camilleri, R. McCallum, Ramon F. Sastre +6 more
2016Gastroenterology118 citations
Semantic Scholar
A Study to Determine the Effects of Food and Multiple Dosing on the Pharmacokinetics of Vorinostat Given Orally to Patients with Advanced Cancer
E. Rubin, N. Agrawal, E. Friedman, Pamela Scott +8 more
2006Clinical Cancer Research115 citations Open access
Semantic Scholar
Multiple‐Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects
R. Krishna, A. Bergman, B. Jin, M. Fallon +19 more
2008Clinical pharmacology and therapy102 citations
Semantic Scholar
Characterization of Etoricoxib, a Novel, Selective COX‐2 Inhibitor
A. Dallob, C. J. Hawkey, H. Greenberg, N. Wight +8 more
2003Journal of clinical pharmacology101 citations
Semantic Scholar
Atazanavir modestly increases plasma levels of raltegravir in healthy subjects.
M. Iwamoto, Larissa A. Wenning, G. Mistry, A. Petry +9 more
2008Clinical Infectious Diseases100 citations Open access
Semantic Scholar
Randomized Controlled Phase Ib Study of Ghrelin Agonist, RM-131, in Type 2 Diabetic Women With Delayed Gastric Emptying
A. Shin, M. Camilleri, I. Busciglio, D. Burton +6 more
2012Diabetes Care96 citations Open access
Semantic Scholar
Absorption, metabolism, and excretion of etoricoxib, a potent and selective cyclooxygenase-2 inhibitor, in healthy male volunteers.
A. Rodrigues, R. A. Halpin, L. Geer, Dong-Hui Cui +6 more
2003Drug Metabolism And Disposition90 citations
Semantic Scholar
Potent and Selective Agonism of the Melanocortin Receptor 4 With MK‐0493 Does Not Induce Weight Loss in Obese Human Subjects: Energy Intake Predicts Lack of Weight Loss Efficacy
R. Krishna, B. Gumbiner, C. Stevens, B. Musser +17 more
2009Clinical pharmacology and therapy86 citations
Semantic Scholar
Single‐ and Multiple‐Dose Pharmacokinetics of Etoricoxib, a Selective Inhibitor of Cyclooxygenase‐2, in Man
N. Agrawal, A. Porras, C. Matthews, Mark J. Rose +9 more
2003Journal of clinical pharmacology86 citations
Semantic Scholar
Lack of a Significant Drug Interaction between Raltegravir and Tenofovir
Larissa A. Wenning, E. Friedman, James T. Kost, Sheila A. Breidinger +8 more
2008Antimicrobial Agents and Chemotherapy85 citations Open access
Semantic Scholar
Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment
K. Ayers, Benjamin S. Glicksberg, A. Garfield, S. Longerich +14 more
2018Journal of Clinical Endocrinology and Metabolism82 citations Open access
Semantic Scholar
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics--results from single oral dose studies in healthy volunteers.
S. Stoch, S. Zajic, Julie A. Stone, Deborah L. Miller +11 more
2013British Journal of Clinical Pharmacology79 citations Open access
Semantic Scholar
Concomitant Use of the Oral Pentavalent Human-Bovine Reassortant Rotavirus Vaccine and Oral Poliovirus Vaccine
M. Ciarlet, Ramei Sani-Grosso, Guo-Jun Yuan, G. Liu +4 more
2008The Pediatric Infectious Disease Journal78 citations
Semantic Scholar
Dose Proportionality of Oral Etoricoxib, a Highly Selective Cyclooxygenase‐2 Inhibitor, in Healthy Volunteers
N. Agrawal, A. Porras, C. Matthews, Eric J. Woolf +4 more
2001Journal of clinical pharmacology73 citations
Semantic Scholar
Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir
M. Iwamoto, Larissa A. Wenning, A. Petry, M. Laethem +10 more
2008Antimicrobial Agents and Chemotherapy71 citations Open access
Semantic Scholar
Single‐Dose Administration of MK‐0657, an NR2B‐Selective NMDA Antagonist, Does Not Result in Clinically Meaningful Improvement in Motor Function in Patients With Moderate Parkinson's Disease
C. Addy, C. Assaid, D. Hreniuk, M. Stroh +12 more
2009Journal of clinical pharmacology66 citations
Semantic Scholar
Efficacy and safety of boceprevir plus peginterferon-ribavirin in patients with HCV G1 infection and advanced fibrosis/cirrhosis.
S. Bruno, J. Vierling, R. Esteban, L. Nyberg +10 more
2013Journal of Hepatology60 citations
Semantic Scholar
Single-dose pharmacokinetics and pharmacodynamics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjects.
R. Krishna, Amit Garg, D. Panebianco, J. Cote +17 more
2009British Journal of Clinical Pharmacology55 citations Open access
Semantic Scholar
Refinement of stopping rules during treatment of hepatitis C genotype 1 infection with boceprevir and peginterferon/ribavirin
I. Jacobson, P. Marcellin, S. Zeuzem, M. Sulkowski +12 more
2012Hepatology53 citations Open access
Semantic Scholar
Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131.
L. van der Ploeg, H. Laken, Shubhangi Sharma, R. Datta +10 more
2014Life Science51 citations
Semantic Scholar
Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects.
G. Mistry, A. Bergman, W. Zheng, D. Hreniuk +5 more
2008British Journal of Clinical Pharmacology51 citations Open access
Semantic Scholar
Multiple‐Dose Pharmacokinetics, Pharmacodynamics, and Safety of Taranabant, a Novel Selective Cannabinoid‐1 Receptor Inverse Agonist, in Healthy Male Volunteers
C. Addy, P. Rothenberg, S. Li, A. Majumdar +17 more
2008Journal of clinical pharmacology50 citations
Semantic Scholar
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Properties of Taranabant, a Novel Selective Cannabinoid‐1 Receptor Inverse Agonist, for the Treatment of Obesity: Results From a Double‐Blind, Placebo‐Controlled, Single Oral Dose Study in Healthy Volunteers
C. Addy, S. Li, N. Agrawal, J. Stone +14 more
2008Journal of clinical pharmacology48 citations
Semantic Scholar
Evaluation of pharmacokinetic parameters and dipeptidyl peptidase-4 inhibition following single doses of sitagliptin in healthy, young Japanese males.
G. Herman, G. Mistry, B. Yi, A. Bergman +10 more
2011British Journal of Clinical Pharmacology45 citations Open access
Semantic Scholar
Relamorelin Relieves Constipation and Accelerates Colonic Transit in a Phase 2, Placebo-Controlled, Randomized Trial.
A. Acosta, M. Camilleri, G. Kolar, J. Iturrino +10 more
2015Clinical Gastroenterology and Hepatology44 citations Open access
Semantic Scholar
Multiple‐Dose Administration of Sitagliptin, a Dipeptidyl Peptidase‐4 Inhibitor, Does Not Alter the Single‐Dose Pharmacokinetics of Rosiglitazone in Healthy Subjects
G. Mistry, A. Bergman, W. Luo, C. Cilissen +5 more
2007Journal of clinical pharmacology44 citations Open access
Semantic Scholar
Effect of Tipranavir-Ritonavir on Pharmacokinetics of Raltegravir
W. Hanley, Larissa A. Wenning, Allison R. Moreau, James T. Kost +6 more
2009Antimicrobial Agents and Chemotherapy43 citations Open access
Semantic Scholar
Effect of L-000845704, an alphaVbeta3 integrin antagonist, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women.
M. Murphy, K. Cerchio, S. Stoch, K. Gottesdiener +2 more
2005Journal of Clinical Endocrinology and Metabolism42 citations
Semantic Scholar
Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers
L. James, R. Iannone, J. Palcza, J. Renger +7 more
2011Psychopharmacology40 citations Open access
Semantic Scholar
Assessment of the CYP3A‐Mediated Drug Interaction Potential of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Volunteers
R. Krishna, A. Bergman, B. Jin, Amit Garg +10 more
2009Journal of clinical pharmacology38 citations
Semantic Scholar
Interaction of Single‐Dose Ezetimibe and Steady‐State Cyclosporine in Renal Transplant Patients
A. Bergman, Joanne Burke, P. Larson, A. Johnson-Levonas +8 more
2006Journal of clinical pharmacology38 citations
Semantic Scholar

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