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R. Bremner · SciRah

Researcher profile · Semantic Scholar

R. Bremner

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R. Bremner — researcher profile on SciRah

h-index: 40
Works: 131
Citations: 5,962

Most-cited papers

Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography
M. Fischer, G. Huber, Susanne C. Beck, N. Tanimoto +10 more
2009PLoS ONE264 citations Open access
Semantic Scholar
E2F1-3 Switch from Activators in Progenitor Cells to Repressors in Differentiating Cells
Jean-Leon Chong, Pamela L. Wenzel, M. Sáenz-Robles, V. Nair +18 more
2009Nature259 citations Open access
Semantic Scholar
Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development
Yufeng Lu, Fion Shiau, Wenyang Yi, Suying Lu +24 more
2019bioRxiv254 citations Open access
Semantic Scholar
The search for the retinoblastoma cell of origin
M. Dyer, R. Bremner
2005Nature Reviews. Cancer207 citations
Semantic Scholar
Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
J. Pearson, Katherine Huang, M. Paçal, S. McCurdy +22 more
2021Cancer Cell162 citations Open access
Semantic Scholar
Division and apoptosis in the E2f-deficient retina
Danian Chen, M. Paçal, Pamela L. Wenzel, P. Knoepfler +2 more
2009Nature150 citations Open access
Semantic Scholar
The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers
Z. Ni, M. E. el Hassan, Zhaodong Xu, Tao Yu +1 more
2008Nature Immunology117 citations
Semantic Scholar
Apical role for BRG1 in cytokine-induced promoter assembly.
Z. Ni, Elizabeth Karaskov, Tao Yu, Steve M. Callaghan +5 more
2005Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
Semantic Scholar
CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
E. Knudsen, V. Kumarasamy, Ram Nambiar, J. Pearson +9 more
2022Cell Reports108 citations Open access
Semantic Scholar
Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina.
Izzy Livne-bar, M. Paçal, Melissa C Cheung, M. Hankin +4 more
2006Proceedings of the National Academy of Sciences of the United States of America108 citations
Semantic Scholar
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome
L. Heisler, D. Torti, P. Boutros, John D. Watson +11 more
2005Nucleic Acids Research96 citations Open access
Semantic Scholar
Unique Requirement for Rb/E2F3 in Neuronal Migration: Evidence for Cell Cycle-Independent Functions
K. Mcclellan, V. Ruzhynsky, D. Douda, J. Vanderluit +6 more
2007Molecular and Cellular Biology95 citations Open access
Semantic Scholar
Rb-Mediated Neuronal Differentiation through Cell-Cycle–Independent Regulation of E2f3a
Danian Chen, R. Opavsky, M. Paçal, N. Tanimoto +4 more
2007PLoS Biology95 citations Open access
Semantic Scholar
Retinoic acid receptor‐related orphan receptor α regulates a subset of cone genes during mouse retinal development
H. Fujieda, R. Bremner, A. Mears, H. Sasaki
2009Journal of Neurochemistry93 citations
Semantic Scholar
A glucose meter interface for point-of-care gene circuit-based diagnostics
Evan Amalfitano, Margot Karlikow, Masoud Norouzi, Katariina Jaenes +20 more
2021Nature Communications78 citations Open access
Semantic Scholar
Maximizing Functional Photoreceptor Differentiation From Adult Human Retinal Stem Cells
Tomoyuki Inoue, Brenda L. K. Coles, Kimberley M. Dorval, R. Bremner +9 more
2009Stem Cells78 citations Open access
Semantic Scholar
A rapid and efficient method to purify proteins at replication forks under native conditions.
K. K. H. Leung, M. E. el Hassan, R. Bremner
2013BioTechniques68 citations Open access
Semantic Scholar
Modifying lipid rafts promotes regeneration and functional recovery.
N. Tassew, Andrea J. Mothe, A. Shabanzadeh, P. Banerjee +4 more
2014Cell Reports62 citations Open access
Semantic Scholar
Transcriptional Activity of the Paired-like Homeodomain Proteins CHX10 and VSX1*
Kimberley M. Dorval, B. Bobechko, K. Ahmad, R. Bremner
2005Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Association of reading disabilities with regions marked by acetylated H3 histones in KIAA0319
J. Couto, Izzy Livne-bar, Katherine Huang, Zhaodong Xu +9 more
2010American Journal of Medical Genetics Part B: Neuropsychiatric Genetics60 citations Open access
Semantic Scholar
Photoreceptor nanotubes mediate the in vivo exchange of intracellular material
Arturo Ortín-Martínez, Nicole E. Yan, E. Tsai, L. Comanita +11 more
2021EMBO Journal59 citations Open access
Semantic Scholar
A G1 Checkpoint Mediated by the Retinoblastoma Protein That Is Dispensable in Terminal Differentiation but Essential for Senescence
S. Talluri, Christian E. Isaac, Mohammad E. Ahmad, Shauna A. Henley +4 more
2009Molecular and Cellular Biology59 citations Open access
Semantic Scholar
CHX10 Targets a Subset of Photoreceptor Genes*
Kimberley M. Dorval, B. Bobechko, H. Fujieda, Shi-Ming Chen +2 more
2006Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Brahma-Related Gene 1-Dependent STAT3 Recruitment at IL-6-Inducible Genes1
Z. Ni, R. Bremner
2007Journal of Immunology53 citations Open access
Semantic Scholar
Pou2f1 and Pou2f2 cooperate to control the timing of cone photoreceptor production in the developing mouse retina
Awais Javed, P. Mattar, Suying Lu, K. Kruczek +5 more
2020Development51 citations Open access
Semantic Scholar
Established and New Mouse Models Reveal E2f1 and Cdk2 Dependency of Retinoblastoma and Expose Strategies to Block Tumor Initiation
Monika Sangwan, S. McCurdy, Izzy Livne-bar, Mohammad E. Ahmad +3 more
2012Oncogene48 citations Open access
Semantic Scholar
Targeting the Ubiquitin–Proteasome System Using the UBA1 Inhibitor TAK-243 is a Potential Therapeutic Strategy for Small-Cell Lung Cancer
S. Majeed, M. Aparnathi, K. Nixon, V. Venkatasubramanian +12 more
2022Clinical Cancer Research40 citations Open access
Semantic Scholar
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy
Arthur Aubry, Tao Yu, R. Bremner
2020Cell Death Discovery40 citations Open access
Semantic Scholar
A multiplexed, next generation sequencing platform for high-throughput detection of SARS-CoV-2
M. Aynaud, J. Hernández, S. Barutcu, Ulrich Braunschweig +19 more
2020Nature Communications40 citations Open access
Semantic Scholar
Properties of STAT1 and IRF1 enhancers and the influence of SNPs
Mohamed A. I. Abou El Hassan, Katherine Huang, Manoja B. K. Eswara, Zhaodong Xu +7 more
2017BMC Molecular Biology40 citations Open access
Semantic Scholar
Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins
D. Zencak, Karine Schouwey, Danian Chen, P. Ekström +4 more
2013Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
Ellen Langille, K. Al-Zahrani, Zhibo Ma, Ming-Gao Liang +32 more
2022Cancer Discovery38 citations Open access
Semantic Scholar
A CDK2 activity signature predicts outcome in CDK2-low cancers
S. McCurdy, M. Pacal, M. Ahmad, R. Bremner
2017Oncogene38 citations
Semantic Scholar
Insights from animal models on the origins and progression of retinoblastoma.
M. Paçal, R. Bremner
2006Current molecular medicine36 citations
Semantic Scholar
Direct and indirect effects of hedgehog pathway activation in the mammalian retina.
Chuan Yu, Chantal J. Mazerolle, S. Thurig, Ya-Ping Wang +3 more
2006Molecular and cellular neurosciences35 citations
Semantic Scholar
FAT4 fine-tunes kidney development by regulating RET signaling
Hong-Tao Zhang, Mazdak Bagherie-Lachidan, Caroline Badouel, Leonie Enderle +5 more
2019Developmental Cell34 citations Open access
Semantic Scholar
The RB Protein Family in Retinal Development and Retinoblastoma: New Insights from New Mouse Models
R. Bremner, Danian Chen, M. Paçal, I. Livne-bar +1 more
2005Developmental Neuroscience33 citations
Semantic Scholar
Functional genomics identifies new synergistic therapies for retinoblastoma
Arthur Aubry, J. Pearson, Katherine Huang, I. Livne-bar +10 more
2020Oncogene31 citations Open access
Semantic Scholar
Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways
Mohamed A. I. Abou El Hassan, Katherine Huang, Manoja B. K. Eswara, Michael Zhao +11 more
2015PLoS ONE31 citations Open access
Semantic Scholar
E2f2 induces cone photoreceptor apoptosis independent of E2f1 and E2f3
D. Chen, Y. Chen, D. Forrest, R. Bremner
2013Cell Death and Differentiation29 citations Open access
Semantic Scholar
Comparison of SARS-CoV-2 indirect and direct RT-qPCR detection methods
J. Pearson, D. Trcka, Suying Lu, S. Hyduk +13 more
2021Virology Journal28 citations Open access
Semantic Scholar
Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post‐mitotic newborn neurons
M. Paçal, R. Bremner
2012Developmental Dynamics27 citations
Semantic Scholar
Cyclins, Cdks, E2f, Skp2, and more at the first international RB Tumor Suppressor Meeting.
R. Bremner, E. Zacksenhaus
2010Cancer Research27 citations
Semantic Scholar
Extracellular phosphorylation drives the formation of neuronal circuitry
Hidekiyo Harada, Nahal Farhani, Xue-Fan Wang, S. Sugita +7 more
2019Nature Chemical Biology25 citations
Semantic Scholar
The origin of human retinoblastoma
R. Bremner, J. Sage
2014Nature25 citations Open access
Semantic Scholar
Histone Deacetylases and the Nuclear Receptor Corepressor Regulate Lytic-Latent Switch Gene 50 in Murine Gammaherpesvirus 68-Infected Macrophages
Megan M Goodwin, Jerome M. Molleston, S. Canny, Mohamed A. I. Abou El Hassan +3 more
2010Journal of Virology25 citations Open access
Semantic Scholar
Induction of the ganglion cell differentiation program in human retinal progenitors before cell cycle exit
M. Paçal, R. Bremner
2014Developmental Dynamics24 citations Open access
Semantic Scholar
A rapid simple approach to quantify chromosome conformation capture
M. E. el Hassan, R. Bremner
2009Nucleic Acids Research24 citations Open access
Semantic Scholar
Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma.
Ran Wei, X. Ren, H. Kong, Zhongping Lv +10 more
2019JCI Insight23 citations Open access
Semantic Scholar
Polycomb Repressive Complex 2 Confers BRG1 Dependency on the CIITA Locus
Mohamed A. I. Abou El Hassan, Tao Yu, Lan Song, R. Bremner
2015Journal of Immunology23 citations
Semantic Scholar

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Danian Chen×9
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J. Pearson×8
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J. Wrana×7
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Katherine Huang×5

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Tao Yu — researcher profile on SciRah

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Arthur Aubry×4

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Mohammad E. Ahmad×4

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