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M. Ono · SciRah

Researcher profile · Semantic Scholar

M. Ono

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M. Ono — researcher profile on SciRah

h-index: 50
Works: 367
Citations: 19K

Most-cited papers

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells
A. Śledzińska, María Vila de Mucha, K. Bergerhoff, A. Hotblack +18 more
2020Immunity182 citations Open access
Semantic Scholar
Control of regulatory T‐cell differentiation and function by T‐cell receptor signalling and Foxp3 transcription factor complexes
M. Ono
2020Immunology177 citations Open access
Semantic Scholar
T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis
B. Kalfaoglu, José Almeida-Santos, C. Tye, Yorifumi Satou +1 more
2020bioRxiv160 citations Open access
Semantic Scholar
A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo
D. Bending, Paz Prieto Martín, Alina Paduraru, Catherine B. Ducker +6 more
2018Journal of Cell Biology86 citations Open access
Semantic Scholar
Nr4a1 and Nr4a3 Reporter Mice Are Differentially Sensitive to T Cell Receptor Signal Strength and Duration
Emma K. Jennings, T. A. Elliot, Natasha Thawait, S. Kanabar +6 more
2020Cell Reports79 citations Open access
Semantic Scholar
T-cell dysregulation in COVID-19
B. Kalfaoglu, José Almeida-Santos, C. Tye, Yorifumi Satou +1 more
2020Biochemical and Biophysical Research Communications - BBRC71 citations Open access
Semantic Scholar
IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation
Diana C. Yánez, H. Sahni, Susan Ross, A. Solanki +11 more
2018European Journal of Immunology58 citations Open access
Semantic Scholar
Cancer radiotheranostics targeting carbonic anhydrase-IX with 111In- and 90Y-labeled ureidosulfonamide scaffold for SPECT imaging and radionuclide-based therapy
Shimpei Iikuni, M. Ono, Hiroyuki Watanabe, Yoichi Shimizu +2 more
2018Theranostics52 citations Open access
Semantic Scholar
Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation
E. Papaioannou, Diana C. Yánez, Susan Ross, C. Lau +7 more
2019Journal of Clinical Investigation48 citations Open access
Semantic Scholar
Radiotheranostics Using a Novel 225Ac-Labeled Radioligand with Improved Pharmacokinetics Targeting Prostate-Specific Membrane Antigen.
Shimpei Iikuni, Yuta Tarumizu, Kazuma Nakashima, Yusuke Higaki +3 more
2021Journal of Medicinal Chemistry37 citations
Semantic Scholar
Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging.
Sho Kaide, Hiroyuki Watanabe, Yoichi Shimizu, Shimpei Iikuni +4 more
2020ACS Chemical Neuroscience34 citations
Semantic Scholar
In Vivo Near-Infrared Fluorescence Imaging Selective for Soluble Amyloid β Aggregates Using y-Shaped BODIPY Derivative.
Takahiro Akasaka, Hiroyuki Watanabe, M. Ono
2023Journal of Medicinal Chemistry31 citations
Semantic Scholar
Development of Novel 111In/225Ac-Labeled Agent Targeting PSMA for Highly Efficient Cancer Radiotheranostics.
Shohei Tsuchihashi, Kazuma Nakashima, Yuta Tarumizu, Hiroaki Ichikawa +3 more
2023Journal of Medicinal Chemistry30 citations
Semantic Scholar
Modulation of the Pharmacokinetics of a Radioligand Targeting Carbonic Anhydrase-IX with Albumin-Binding Moieties.
Shimpei Iikuni, Yuya Okada, Yoichi Shimizu, Hiroyuki Watanabe +1 more
2021Molecular Pharmaceutics27 citations
Semantic Scholar
18F-FPYBF-2, a new F-18-labelled amyloid imaging PET tracer: first experience in 61 volunteers and 55 patients with dementia
T. Higashi, R. Nishii, S. Kagawa, Y. Kishibe +12 more
2018Annals of Nuclear Medicine26 citations Open access
Semantic Scholar
Activatable fluorescence imaging of macrophages in atherosclerotic plaques using iron oxide nanoparticles conjugated with indocyanine green.
Hiroyuki Ikeda, A. Ishii, Kohei Sano, Hideo Chihara +6 more
2018Atherosclerosis26 citations Open access
Semantic Scholar
From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics
D. Bending, M. Ono
2018Clinical and Experimental Immunology25 citations Open access
Semantic Scholar
First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [18F]FB(ePEG12)12-Exendin-4: A Phase 1 Clinical Study Targeting GLP-1 Receptor Expression Cells in Pancreas
Hiroyuki Fujimoto, N. Fujita, K. Hamamatsu, Takaaki Murakami +17 more
2021Frontiers in Endocrinology24 citations Open access
Semantic Scholar
Enhanced Delivery of Radiolabeled Polyoxazoline into Tumors via Self-Aggregation under Hyperthermic Conditions.
Kohei Sano, Yuko Kanada, Katsushi Takahashi, Ning Ding +4 more
2018Molecular Pharmaceutics21 citations Open access
Semantic Scholar
The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection
C. Lau, Jasmine Rowell, Diana C. Yánez, A. Solanki +3 more
2021Development18 citations Open access
Semantic Scholar
Highly Selective Tau-SPECT Imaging Probes for Detection of Neurofibrillary Tangles in Alzheimer’s Disease
M. Ono, Hiroyuki Watanabe, Ayane Kitada, K. Matsumura +2 more
201818 citations
Semantic Scholar
Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology.
Sho Kaide, Hiroyuki Watanabe, Shimpei Iikuni, M. Hasegawa +2 more
2021ACS Chemical Neuroscience17 citations
Semantic Scholar
Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging.
H. Kimura, Y. Ogawa, Hiroyuki Fujimoto, E. Mukai +13 more
2018Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar
Core Binding Site of a Thioflavin-T-Derived Imaging Probe on Amyloid β Fibrils Predicted by Computational Methods.
Ryoko Kawai, M. Araki, Masashi Yoshimura, N. Kamiya +3 more
2018ACS Chemical Neuroscience15 citations
Semantic Scholar
Synthesis and biological evaluation of F-18 labeled tetrahydroisoquinoline derivatives targeting orexin 1 receptor.
Hiroyuki Watanabe, Kengo Fukui, Yoichi Shimizu, Yuki Idoko +4 more
2019Bioorganic & Medicinal Chemistry Letters14 citations
Semantic Scholar
Development of an 111In-Labeled Glucagon-Like Peptide-1 Receptor-Targeting Exendin-4 Derivative that Exhibits Reduced Renal Uptake.
Shimpei Iikuni, Ichiro Kamei, Takaki Ohara, Hiroyuki Watanabe +1 more
2022Molecular Pharmaceutics13 citations
Semantic Scholar
Stabilization Mechanism for a Non-fibrillar Amyloid β Oligomer Based on Formation of a Hydrophobic Core Determined by Dissipative Particle Dynamics.
Ryoko Kawai, S. Chiba, K. Okuwaki, R. Kanada +4 more
2020ACS Chemical Neuroscience13 citations Open access
Semantic Scholar
Development of the 99mTc-Hydroxamamide Complex as a Probe Targeting Carbonic Anhydrase IX.
Shimpei Iikuni, Keiichi Tanimura, Hiroyuki Watanabe, Yoichi Shimizu +2 more
2019Molecular Pharmaceutics13 citations Open access
Semantic Scholar
Novel fluorescence probes based on the chalcone scaffold for in vitro staining of β-amyloid plaques.
Hiroyuki Watanabe, H. Saji, M. Ono
2018Bioorganic & Medicinal Chemistry Letters13 citations
Semantic Scholar
Elucidating T Cell Activation-Dependent Mechanisms for Bifurcation of Regulatory and Effector T Cell Differentiation by Multidimensional and Single-Cell Analysis
A. Bradley, T. Hashimoto, M. Ono
2018Frontiers in Immunology13 citations Open access
Semantic Scholar
Initial evaluation of PET/CT with 18F‐FSU‐880 targeting prostate‐specific membrane antigen in prostate cancer patients
T. Saga, Y. Nakamoto, T. Ishimori, Takahiro Inoue +11 more
2019Cancer Science12 citations Open access
Semantic Scholar
Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus
K. Mengrelis, C. Lau, Jasmine Rowell, A. Solanki +5 more
2019Frontiers in Immunology12 citations Open access
Semantic Scholar
Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imaging.
Sho Kaide, M. Ono, Hiroyuki Watanabe, Yoichi Shimizu +5 more
2018Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar
Development of Novel Trifunctional Chelating Agents That Enhance Tumor Retention of Radioimmunoconjugates.
Kazuma Nakashima, Hiroyuki Watanabe, M. Ono
2023Journal of Medicinal Chemistry11 citations
Semantic Scholar
Synthesis and evaluation of indium-111-labeled imidazothiadiazole sulfonamide derivative for single photon emission computed tomography imaging targeting carbonic anhydrase-IX.
Shimpei Iikuni, Yuya Okada, Yoichi Shimizu, Hiroyuki Watanabe +1 more
2020Bioorganic & Medicinal Chemistry Letters11 citations
Semantic Scholar
Immuno-moodulin: a new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells.
G. Piras, L. Rattazzi, N. Paschalidis, S. Oggero +8 more
2020Brain, behavior, and immunity11 citations Open access
Semantic Scholar
Misery perfusion and amyloid deposition in atherosclerotic major cerebral artery disease
H. Yamauchi, S. Kagawa, Masaaki Takahashi, N. Oishi +2 more
2019NeuroImage: Clinical11 citations Open access
Semantic Scholar
Synthesis and Evaluation of 18F-Labeled Chalcone Analogue for Detection of α-Synuclein Aggregates in the Brain Using the Mouse Model.
Sho Kaide, Hiroyuki Watanabe, Shimpei Iikuni, M. Hasegawa +1 more
2022ACS Chemical Neuroscience10 citations
Semantic Scholar
Spatial Patterns of Amyloid Deposition in Patients with Chronic Focal or Diffuse Traumatic Brain Injury Using 18F-FPYBF-2 PET
S. Ubukata, N. Oishi, T. Higashi, S. Kagawa +8 more
2020Neuropsychiatric Disease and Treatment10 citations Open access
Semantic Scholar
Structure-Activity Relationships of Styrylquinoline and Styrylquinoxaline Derivatives as α-Synuclein Imaging Probes.
K. Nakagawa, Hiroyuki Watanabe, Sho Kaide, M. Ono
2022ACS Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Development of a novel radiotheranostic platform with a DOTA-based trifunctional chelating agent.
Kazuma Nakashima, Shimpei Iikuni, Hiroyuki Watanabe, M. Ono
2021Chemical Communications9 citations
Semantic Scholar
PET imaging and pharmacological therapy targeting carbonic anhydrase-IX high-expressing tumors using US2 platform based on bivalent ureidosulfonamide
Shimpei Iikuni, Hiroyuki Watanabe, Yoichi Shimizu, Y. Nakamoto +1 more
2020PLoS ONE9 citations Open access
Semantic Scholar
Synthesis and evaluation of 68Ga-labeled imidazothiadiazole sulfonamide derivatives for PET imaging of carbonic anhydrase-IX.
Kazuma Nakashima, Shimpei Iikuni, Yuya Okada, Hiroyuki Watanabe +3 more
2020Nuclear Medicine and Biology9 citations Open access
Semantic Scholar
Development of Technetium-99m-Labeled BODIPY-Based Probes Targeting Lipid Droplets Toward the Diagnosis of Hyperlipidemia-Related Diseases
Yoichi Shimizu, Keiichi Tanimura, Shimpei Iikuni, Hiroyuki Watanabe +2 more
2019Molecules9 citations Open access
Semantic Scholar
Synthesis and evaluation of novel two-photon fluorescence probes for in vivo imaging of amylin aggregates in the pancreas
Hiroyuki Watanabe, Y. Miki, Yoichi Shimizu, H. Saji +1 more
2019Dyes and pigments9 citations
Semantic Scholar
Development of a resonant-type microwave reactor and its application to the synthesis of PET radiopharmaceuticals
H. Kimura, Yusuke Yagi, Noriyuki Ohneda, Hiromichi Odajima +2 more
20189 citations
Semantic Scholar
Flumioxazin metabolism in pregnant animals and cell‐based protoporphyrinogen IX oxidase (PPO) inhibition assay of fetal metabolites in various animal species to elucidate the mechanism of the rat‐specific developmental toxicity
J. Abe, N. Isobe, K. Mikata, H. Nagahori +4 more
2018Toxicology and Applied Pharmacology9 citations
Semantic Scholar
Structure-Activity Relationships of Radioiodinated Benzoimidazopyridine Derivatives for Detection of Tau Pathology.
Sho Kaide, M. Ono, Hiroyuki Watanabe, Ayane Kitada +4 more
2018ACS Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Synthesis and Evaluation of Novel 111In-Labeled Picolinic Acid-Based Radioligands Containing an Albumin Binder for Development of a Radiotheranostic Platform.
Shimpei Iikuni, Yuta Tarumizu, Shohei Tsuchihashi, Takaki Ohara +2 more
2022Molecular Pharmaceutics8 citations
Semantic Scholar
Synthesis and Evaluation of Novel Technetium-99m-hydroxamamide Complex Based on Imidazothiadiazole Sulfonamide Targeting Carbonic Anhydrase-IX for Tumor Imaging.
Shimpei Iikuni, Anna Kitano, Hiroyuki Watanabe, Yoichi Shimizu +1 more
2020Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar

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