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M. Hasegawa · SciRah

Researcher profile · Semantic Scholar

M. Hasegawa

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M. Hasegawa — researcher profile on SciRah

h-index: 93
Works: 381
Citations: 36K

Most-cited papers

Structure-based Classification of Tauopathies
Yang Shi, Wen-Juan Zhang, Yang Yang, A. Murzin +23 more
2021Nature721 citations Open access
Semantic Scholar
Structures of α-Synuclein Filaments from Multiple System Atrophy
M. Schweighauser, Yang Shi, A. Tarutani, F. Kametani +11 more
2020Nature656 citations Open access
Semantic Scholar
Novel tau filament fold in corticobasal degeneration
Wen-Juan Zhang, A. Tarutani, K. Newell, A. Murzin +11 more
2020Nature467 citations Open access
Semantic Scholar
Structures of α-synuclein filaments from human brains with Lewy pathology
Yang Yang, Yang Shi, M. Schweighauser, Xianjun Zhang +16 more
2022Nature415 citations Open access
Semantic Scholar
Structure of pathological TDP-43 filaments from ALS with FTLD
Diana Arseni, M. Hasegawa, A. Murzin, F. Kametani +3 more
2021Nature285 citations Open access
Semantic Scholar
LATE-NC staging in routine neuropathologic diagnosis: an update
P. Nelson, Edward B. Lee, M. Cykowski, I. Alafuzoff +46 more
2022Acta Neuropathologica156 citations Open access
Semantic Scholar
Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy
S. Lövestam, M. Schweighauser, T. Matsubara, S. Murayama +8 more
2021FEBS Open Bio115 citations Open access
Semantic Scholar
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes
Aysegul Dilsizoglu Senol, M. Samarani, S. Syan, Carlos M. A. Guardia +7 more
2021PLoS Biology108 citations Open access
Semantic Scholar
The basis of clinicopathological heterogeneity in TDP-43 proteinopathy
Ito Kawakami, T. Arai, M. Hasegawa
2019Acta Neuropathologica105 citations Open access
Semantic Scholar
Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy
S. Lövestam, M. Schweighauser, S. Murayama, Yuko Saito +8 more
2020103 citations Open access
Semantic Scholar
Imaging α-synuclein pathologies in animal models and patients with Parkinson’s and related diseases
H. Endo, M. Ono, Yuhei Takado, K. Matsuoka +30 more
2020bioRxiv101 citations Open access
Semantic Scholar
The Wnt/Ca2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes
Jessica Y. Vargas, F. Loría, Yuan-Ju Wu, G. Córdova +7 more
2019EMBO Journal87 citations Open access
Semantic Scholar
Comparison of Common and Disease-Specific Post-translational Modifications of Pathological Tau Associated With a Wide Range of Tauopathies
F. Kametani, Mari Yoshida, T. Matsubara, S. Murayama +8 more
2020Frontiers in Neuroscience74 citations Open access
Semantic Scholar
Mutations in CHCHD2 cause α-synuclein aggregation.
Aya Ikeda, Kenya Nishioka, Hong-Rui Meng, M. Takanashi +20 more
2019Human Molecular Genetics66 citations
Semantic Scholar
Ultrastructural and biochemical classification of pathogenic tau, α-synuclein and TDP-43
A. Tarutani, T. Adachi, H. Akatsu, Y. Hashizume +7 more
2022Acta Neuropathologica58 citations Open access
Semantic Scholar
α-synuclein strains that cause distinct pathologies differentially inhibit proteasome
G. Suzuki, Sei Imura, M. Hosokawa, R. Katsumata +4 more
2020bioRxiv57 citations Open access
Semantic Scholar
LATE to the PART-y
K. Josephs, I. Mackenzie, M. Frosch, E. Bigio +18 more
2019Brain : a journal of neurology56 citations Open access
Semantic Scholar
Cryo‐EM structures of tau filaments from SH‐SY5Y cells seeded with brain extracts from cases of Alzheimer's disease and corticobasal degeneration
A. Tarutani, S. Lövestam, Xianjun Zhang, A. Kotecha +8 more
2023bioRxiv54 citations Open access
Semantic Scholar
Tau and TDP-43 accumulation of the basal nucleus of Meynert in individuals with cerebral lobar infarcts or hemorrhage
H. Hatsuta, M. Takao, Akane Nogami, A. Uchino +8 more
2019Acta Neuropathologica Communications44 citations Open access
Semantic Scholar
Human tauopathy-derived tau strains determine the substrates recruited for templated amplification
A. Tarutani, Haruka Miyata, T. Nonaka, K. Hasegawa +7 more
2021Brain : a journal of neurology35 citations Open access
Semantic Scholar
Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging.
Sho Kaide, Hiroyuki Watanabe, Yoichi Shimizu, Shimpei Iikuni +4 more
2020ACS Chemical Neuroscience34 citations
Semantic Scholar
Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration.
Y. Riku, Y. Iwasaki, Shinsuke Ishigaki, A. Akagi +12 more
2022Brain : a journal of neurology33 citations Open access
Semantic Scholar
TDP‐43 Proteinopathy Presenting with Typical Symptoms of Parkinson's Disease
Rika Yamashita, Goichi Beck, Yuki Yonenobu, Kimiko Inoue +5 more
2022Movement Disorders33 citations
Semantic Scholar
Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body
Shiori Awa, G. Suzuki, Masami Masuda-Suzukake, T. Nonaka +2 more
2022Scientific Reports33 citations Open access
Semantic Scholar
Early-life stress induces the development of Alzheimer's disease pathology via angiopathy.
Tomoko Tanaka, S. Hirai, M. Hosokawa, T. Saito +4 more
2020Experimental Neurology33 citations
Semantic Scholar
Tau isoform expression and phosphorylation in marmoset brains
Govinda Sharma, Anni Huo, Taeko Kimura, Seiji Shiozawa +11 more
2019Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Structurally Distinct α-Synuclein Fibrils Induce Robust Parkinsonian Pathology
H. Hayakawa, R. Nakatani, K. Ikenaka, C. Aguirre +10 more
2019Movement Disorders32 citations Open access
Semantic Scholar
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy
Chao-xiu Qi, M. Hasegawa, Masaki Takao, M. Sakai +8 more
2023bioRxiv31 citations Open access
Semantic Scholar
Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model.
Taisuke Kato, Riichiroh Manabe, H. Igarashi, F. Kametani +26 more
2021Journal of Clinical Investigation30 citations Open access
Semantic Scholar
Phosphorylated and aggregated TDP-43 with seeding properties are induced upon mutant Huntingtin (mHtt) polyglutamine expression in human cellular models
L. Coudert, T. Nonaka, E. Bernard, M. Hasegawa +2 more
2019Cellular and Molecular Life Sciences30 citations Open access
Semantic Scholar
Tau Filaments from Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) adopt the CTE Fold
Chao-xiu Qi, Bert M. Verheijen, Y. Kokubo, Yang Shi +15 more
2023bioRxiv27 citations Open access
Semantic Scholar
Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms.
M. Hosokawa, Masami Masuda-Suzukake, H. Shitara, Aki Shimozawa +6 more
2021Brain : a journal of neurology25 citations Open access
Semantic Scholar
Distinct phosphorylation profiles of tau in brains of patients with different tauopathies.
N. Samimi, Govinda Sharma, Taeko Kimura, T. Matsubara +11 more
2021Neurobiology of Aging24 citations Open access
Semantic Scholar
Prion-like properties of assembled TDP-43.
T. Nonaka, M. Hasegawa
2019Current Opinion in Neurobiology24 citations Open access
Semantic Scholar
Effect of L-DOPA/Benserazide on Propagation of Pathological α-Synuclein
Aki Shimozawa, Yuuki Fujita, Hiromi Kondo, Yu Takimoto +4 more
2019Frontiers in Neuroscience24 citations Open access
Semantic Scholar
Intracellular dynamics of Ataxin-2 in the human brains with normal and frontotemporal lobar degeneration with TDP-43 inclusions
Ryohei Watanabe, Shinji Higashi, T. Nonaka, Ito Kawakami +6 more
2020Acta Neuropathologica Communications23 citations Open access
Semantic Scholar
Tau Protein and Frontotemporal Dementias.
M. Goedert, M. Spillantini, B. Falcon, Wen-Juan Zhang +4 more
2021Advances in Experimental Medicine and Biology22 citations
Semantic Scholar
Nasal vaccine delivery attenuates brain pathology and cognitive impairment in tauopathy model mice
Hiroki Takeuchi, K. Imamura, Bin Ji, Kayoko Tsukita +16 more
2020npj Vaccines21 citations Open access
Semantic Scholar
Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: An immunohistochemical analysis in autopsy cases including cases treated with aggressive antiviral therapies
Hiroaki Miyahara, A. Akagi, Y. Riku, J. Sone +7 more
2022Brain Pathology18 citations Open access
Semantic Scholar
Phosphorylation of α-synuclein at T64 results in distinct oligomers and exerts toxicity in models of Parkinson’s disease
Hideaki Matsui, S. Ito, Hideki Matsui, J. Ito +18 more
2023Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology.
Sho Kaide, Hiroyuki Watanabe, Shimpei Iikuni, M. Hasegawa +2 more
2021ACS Chemical Neuroscience17 citations
Semantic Scholar
Tau progression in single severe frontal traumatic brain injury in human brains.
Yasushi Okamura, Ito Kawakami, Katsushige Watanabe, Kenichi Oshima +4 more
2019Journal of Neurological Sciences17 citations
Semantic Scholar
Distinct tau folds initiate templated seeding and alter the post-translational modification profile
A. Tarutani, F. Kametani, Marina Tahira, Yuko Saito +6 more
2023Brain : a journal of neurology15 citations Open access
Semantic Scholar
Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy
Yuki Yonenobu, Goichi Beck, Kansuke Kido, N. Maeda +10 more
2023Neuropathology (Kyoto. 1993)15 citations
Semantic Scholar
Factors associated with development and distribution of granular/fuzzy astrocytes in neurodegenerative diseases
Tomoko Miki, O. Yokota, Takashi Haraguchi, H. Ishizu +6 more
2020Brain Pathology15 citations Open access
Semantic Scholar
Structure of NFT: Biochemical Approach.
M. Hasegawa
2019Advances in Experimental Medicine and Biology15 citations
Semantic Scholar
Co-morbidity of progressive supranuclear palsy and amyotrophic lateral sclerosis: a clinical-pathological case report
K. Fujita, T. Matsubara, Ryosuke Miyamoto, H. Sumikura +12 more
2019BMC Neurology15 citations Open access
Semantic Scholar
Age-Dependent Formation of TMEM106B Amyloid Filaments in Human Brain
M. Schweighauser, Diana Arseni, Melissa Huang, S. Lövestam +25 more
2021bioRxiv14 citations Open access
Semantic Scholar
Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice
Masami Masuda-Suzukake, G. Suzuki, M. Hosokawa, T. Nonaka +2 more
2020Brain Communications13 citations Open access
Semantic Scholar
Globular glial tauopathy Type I presenting with behavioral variant frontotemporal dementia
M. Hirano, S. Iritani, Hiroshige Fujishiro, Youta Torii +9 more
2020Neuropathology (Kyoto. 1993)13 citations
Semantic Scholar

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S. Murayama×15
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Yuko Saito×13
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M. Goedert×12
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A. Tarutani×10

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K. Hasegawa — researcher profile on SciRah

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B. Ghetti — researcher profile on SciRah

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A. Murzin — researcher profile on SciRah

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Yang Shi — researcher profile on SciRah