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F. Lardon · SciRah

Researcher profile · Semantic Scholar

F. Lardon

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F. Lardon — researcher profile on SciRah

h-index: 49
Works: 220
Citations: 7,518

Most-cited papers

The potential and controversy of targeting STAT family members in cancer.
Y. Verhoeven, Sam Tilborghs, J. Jacobs, J. De Waele +9 more
2020Seminars in Cancer Biology322 citations Open access
Semantic Scholar
A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma.
Laure Sorber, K. Zwaenepoel, V. Deschoolmeester, G. Roeyen +3 more
2017Journal of Molecular Diagnostics192 citations Open access
Semantic Scholar
CD70: An emerging target in cancer immunotherapy.
J. Jacobs, V. Deschoolmeester, K. Zwaenepoel, C. Rolfo +5 more
2015Pharmacology and Therapeutics186 citations Open access
Semantic Scholar
The CD70-CD27 axis in oncology: the new kids on the block
T. Flieswasser, Astrid Van Den Eynde, J. V. Van Audenaerde, J. De Waele +6 more
2022Journal of experimental & clinical cancer research : CR176 citations Open access
Semantic Scholar
Circulating cell-free nucleic acids and platelets as a liquid biopsy in the provision of personalized therapy for lung cancer patients.
Laure Sorber, K. Zwaenepoel, V. Deschoolmeester, P. V. Van Schil +4 more
2017Lung Cancer143 citations
Semantic Scholar
Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells
J. Van Loenhout, T. Flieswasser, Laurie Freire Boullosa, J. De Waele +12 more
2019Cancers105 citations Open access
Semantic Scholar
Spotlight on Volasertib: Preclinical and Clinical Evaluation of a Promising Plk1 Inhibitor
J. Van den Bossche, F. Lardon, V. Deschoolmeester, I. De Pauw +5 more
2016Medicinal research reviews (Print)104 citations
Semantic Scholar
A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy
J. De Waele, Tias Verhezen, S. van der Heijden, Z. Berneman +4 more
2021Journal of experimental & clinical cancer research : CR103 citations Open access
Semantic Scholar
IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts
Astrid Van Den Eynde, Laura Gehrcken, Tias Verhezen, Ho-Wa Lau +23 more
2024Journal of Hematology & Oncology95 citations Open access
Semantic Scholar
Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol
Laure Sorber, K. Zwaenepoel, J. Jacobs, K. De Winne +10 more
2019Cancers94 citations Open access
Semantic Scholar
Cellular senescence in cancer: clinical detection and prognostic implications
A. Domen, C. Deben, Jasper Verswyvel, T. Flieswasser +4 more
2022Journal of experimental & clinical cancer research : CR88 citations Open access
Semantic Scholar
TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value.
C. Deben, V. Deschoolmeester, F. Lardon, C. Rolfo +1 more
2016Critical reviews in oncology/hematology87 citations
Semantic Scholar
Immune Checkpoint Modulation in Colorectal Cancer: What's New and What to Expect
J. Jacobs, E. Smits, F. Lardon, P. Pauwels +1 more
2015Journal of Immunological Research72 citations Open access
Semantic Scholar
OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening
C. Deben, Edgar Cardenas De La Hoz, Maxim Le Compte, P. V. Van Schil +10 more
2021bioRxiv71 citations Open access
Semantic Scholar
RANK/RANKL signaling inhibition may improve the effectiveness of checkpoint blockade in cancer treatment.
P. V. van Dam, Y. Verhoeven, X. Trinh, A. Wouters +5 more
2019Critical reviews in oncology/hematology70 citations Open access
Semantic Scholar
Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma
J. Van Loenhout, Laurie Freire Boullosa, D. Quatannens, J. De Waele +10 more
2021Cells66 citations Open access
Semantic Scholar
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer
C. Deben, A. Wouters, K. O. de Beeck, J. Van den Bossche +8 more
2015OncoTarget65 citations Open access
Semantic Scholar
Interleukin-15 stimulates natural killer cell-mediated killing of both human pancreatic cancer and stellate cells
J. V. Van Audenaerde, J. De Waele, E. Marcq, J. Van Loenhout +9 more
2017OncoTarget63 citations Open access
Semantic Scholar
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation
J. Jacobs, V. Deschoolmeester, K. Zwaenepoel, T. Flieswasser +10 more
2018Oncoimmunology59 citations Open access
Semantic Scholar
APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.
C. Deben, F. Lardon, A. Wouters, Ken Op de Beeck +7 more
2016Cancer Letters59 citations
Semantic Scholar
Recent insights in the PI3K/Akt pathway as a promising therapeutic target in combination with EGFR‐targeting agents to treat head and neck squamous cell carcinoma
Hannah Zaryouh, I. De Pauw, H. Baysal, M. Peeters +3 more
2021Medicinal research reviews (Print)58 citations Open access
Semantic Scholar
Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer
J. Jacobs, K. Zwaenepoel, C. Rolfo, J. Van den Bossche +8 more
2015OncoTarget58 citations Open access
Semantic Scholar
Decreased expression of ABAT and STC2 hallmarks ER‐positive inflammatory breast cancer and endocrine therapy resistance in advanced disease
M. Jansen, Leen Sas, A. Sieuwerts, C. Van Cauwenberghe +19 more
2015Molecular Oncology57 citations Open access
Semantic Scholar
Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer
A. Domen, D. Quatannens, S. Zanivan, C. Deben +11 more
2021Cancers55 citations Open access
Semantic Scholar
Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress
C. Deben, V. Deschoolmeester, J. De Waele, J. Jacobs +7 more
2018Cancers55 citations Open access
Semantic Scholar
In vitro and in vivo investigations on the antitumour activity of Chelidonium majus.
Rica Capistrano I, A. Wouters, F. Lardon, C. Gravekamp +2 more
2015Phytomedicine54 citations Open access
Semantic Scholar
Clinically Relevant Chemotherapeutics Have the Ability to Induce Immunogenic Cell Death in Non-Small Cell Lung Cancer
T. Flieswasser, J. Van Loenhout, Laurie Freire Boullosa, Astrid Van Den Eynde +6 more
2020Cells50 citations Open access
Semantic Scholar
The Right Partner in Crime: Unlocking the Potential of the Anti-EGFR Antibody Cetuximab via Combination With Natural Killer Cell Chartering Immunotherapeutic Strategies
H. Baysal, I. De Pauw, Hannah Zaryouh, M. Peeters +4 more
2021Frontiers in Immunology48 citations Open access
Semantic Scholar
Specialized Blood Collection Tubes for Liquid Biopsy: Improving the Pre-analytical Conditions
Laure Sorber, K. Zwaenepoel, J. Jacobs, K. De Winne +9 more
2019Molecular Diagnosis & Therapy44 citations
Semantic Scholar
Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade
J. De Waele, E. Marcq, J. V. Van Audenaerde, J. Van Loenhout +13 more
2018Oncoimmunology42 citations Open access
Semantic Scholar
Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines
I. De Pauw, F. Lardon, J. Van den Bossche, H. Baysal +6 more
2018Molecular Oncology41 citations Open access
Semantic Scholar
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer
Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, Felicia Rodrigues Fortes +12 more
2023npj Precision Oncology39 citations Open access
Semantic Scholar
Cetuximab-induced natural killer cell cytotoxicity in head and neck squamous cell carcinoma cell lines: investigation of the role of cetuximab sensitivity and HPV status
H. Baysal, I. De Pauw, Hannah Zaryouh, J. De Waele +7 more
2020British Journal of Cancer39 citations Open access
Semantic Scholar
Prognostic implications of cellular senescence in resected non-small cell lung cancer
A. Domen, C. Deben, I. De Pauw, Christophe Hermans +15 more
2021Translational Lung Cancer Research36 citations Open access
Semantic Scholar
Targeting hedgehog signaling in pancreatic ductal adenocarcinoma.
D. Quatannens, Y. Verhoeven, P. V. van Dam, F. Lardon +5 more
2022Pharmacology and Therapeutics34 citations
Semantic Scholar
Novel combination immunotherapy for pancreatic cancer: potent anti‐tumor effects with CD40 agonist and interleukin‐15 treatment
J. V. Van Audenaerde, E. Marcq, B. von Scheidt, Ashleigh S. Davey +12 more
2020Clinical & Translational Immunology30 citations Open access
Semantic Scholar
RANK-RANKL Signaling in Cancer of the Uterine Cervix: A Review
P. V. van Dam, Y. Verhoeven, J. Jacobs, A. Wouters +10 more
2019International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
Deep sequencing of the TP53 gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of TP53 variants
C. Deben, J. Van den Bossche, N. Van Der Steen, F. Lardon +9 more
2017Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine29 citations Open access
Semantic Scholar
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
Carolien Boeckx, L. Blockx, K. O. de Beeck, Ridha Limame +7 more
2015American Journal of Cancer Research28 citations
Semantic Scholar
Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers
Laurie Freire Boullosa, J. Van Loenhout, T. Flieswasser, Christophe Hermans +8 more
2023Antioxidants26 citations Open access
Semantic Scholar
The effect of local non‐thermal plasma therapy on the cancer‐immunity cycle in a melanoma mouse model
A. Lin, J. De Backer, D. Quatannens, B. Cuypers +11 more
2022Bioengineering & Translational Medicine26 citations Open access
Semantic Scholar
In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53
J. Van den Bossche, C. Deben, I. De Pauw, H. Lambrechts +9 more
2019Molecular Oncology26 citations Open access
Semantic Scholar
The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines
Carolien Boeckx, J. Van den Bossche, I. De Pauw, M. Peeters +3 more
2015BMC Research Notes25 citations Open access
Semantic Scholar
The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma
Mohammad Krayem, Malak Sabbah, Ahmad Najem, A. Wouters +7 more
2019Cancers22 citations Open access
Semantic Scholar
Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition
C. Deben, L. F. Boullosa, Felicia Rodrigues Fortes, Edgar Cardenas De La Hoz +12 more
2024Journal of experimental & clinical cancer research : CR21 citations Open access
Semantic Scholar
The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An In Vitro Study on a Novel Combination Strategy
Hannah Zaryouh, I. De Pauw, H. Baysal, P. Pauwels +4 more
2021Frontiers in Oncology18 citations Open access
Semantic Scholar
Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines
I. De Pauw, A. Wouters, J. Van den Bossche, V. Deschoolmeester +5 more
2017Cancer Biotherapy and Radiopharmaceuticals18 citations
Semantic Scholar
The prognostic impact of the immune signature in head and neck squamous cell carcinoma
H. Baysal, V. Siozopoulou, Hannah Zaryouh, Christophe Hermans +12 more
2022Frontiers in Immunology17 citations Open access
Semantic Scholar
Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis.
Maxim Le Compte, Edgar Cardenas De La Hoz, Sofía Peeters, E. Smits +7 more
2022Journal of Visualized Experiments17 citations
Semantic Scholar
Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases.
P. Beckers, M. Versteegh, T. V. van Brakel, J. Braun +14 more
2019Annals of Thoracic Surgery17 citations Open access
Semantic Scholar

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M. Peeters×28
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M. Peeters — researcher profile on SciRah
P. Pauwels×26
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C. Deben×21
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J. Jacobs — researcher profile on SciRah

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