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J. Yau · SciRah

Researcher profile · Semantic Scholar

J. Yau

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J. Yau — researcher profile on SciRah

h-index: 36
Works: 81
Citations: 4,357

Most-cited papers

Postnatal Handling Increases the Expression of cAMP-Inducible Transcription Factors in the Rat Hippocampus: The Effects of Thyroid Hormones and Serotonin
M. Meaney, J. Diorio, D. Francis, S. Weaver +3 more
2000Journal of Neuroscience273 citations Open access
Semantic Scholar
5'-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events.
J. McCormick, V. Lyons, M. Jacobson, J. Noble +8 more
2000Molecular Endocrinology268 citations Open access
Semantic Scholar
11β-Hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics
T. Sandeep, J. Yau, Alasdair M. J. MacLullich, J. Noble +3 more
2004249 citations Open access
Semantic Scholar
Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments
J. Yau, J. Noble, C. Kenyon, C. Hibberd +3 more
2001Proceedings of the National Academy of Sciences of the United States of America226 citations Open access
Semantic Scholar
Cloning and production of antisera to human placental 11 beta-hydroxysteroid dehydrogenase type 2.
Roger W. Brown, K. E. Chapman, Y. Kotelevtsev, J. Yau +8 more
1996Biochemical Journal209 citations Open access
Semantic Scholar
Glucocorticoids, hippocampal corticosteroid receptor gene expression and antidepressant treatment: relationship with spatial learning in young and aged rats.
J. Yau, T. Olsson, R. G. M. Morris, M. Meaney +1 more
1995Neuroscience186 citations
Semantic Scholar
Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia
M. Lai, K. Horsburgh, S. Bae, Roderick N. Carter +8 more
2007European Journal of Neuroscience163 citations
Semantic Scholar
11 beta-hydroxysteroid dehydrogenase in vascular smooth muscle and heart: implications for cardiovascular responses to glucocorticoids.
B. Walker, J. Yau, L. Brett, J. Seckl +3 more
1991Endocrinology145 citations
Semantic Scholar
Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11β-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice
J. Yau, K. McNair, J. Noble, D. Brownstein +6 more
2007Journal of Neuroscience136 citations Open access
Semantic Scholar
Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease.
J. Yau, S. Rasmuson, Ruth Andrew, M. Graham +5 more
2003Neuroscience127 citations
Semantic Scholar
11β-hydroxysteroid dehydrogenase type 1 expression is increased in the aged mouse hippocampus and parietal cortex and causes memory impairments
M. Holmes, Roderick N. Carter, J. Noble, Shruti S. Chitnis +5 more
2010Journal of Neuroscience111 citations Open access
Semantic Scholar
Chronic Treatment with the Antidepressant Amitriptyline Prevents Impairments in Water Maze Learning in Aging Rats
J. Yau, J. Noble, C. Hibberd, W. Rowe +3 more
2002Journal of Neuroscience107 citations Open access
Semantic Scholar
Glucocorticoids and the ageing hippocampus
C. Hibberd, J. Yau, J. Seckl
2000Journal of Anatomy107 citations
Semantic Scholar
Cholestenoic acids regulate motor neuron survival via liver X receptors.
S. Theofilopoulos, William J. Griffiths, P. J. Crick, Shan-Zheng Yang +32 more
2014Journal of Clinical Investigation105 citations Open access
Semantic Scholar
Partial deficiency or short-term inhibition of 11β-hydroxysteroid dehydrogenase type 1 improves cognitive function in ageing mice
K. Sooy, S. Webster, J. Noble, M. Binnie +3 more
2010Journal of Neuroscience102 citations Open access
Semantic Scholar
Impact of adrenalectomy on 5-HT6 and 5-HT7 receptor gene expression in the rat hippocampus.
J. Yau, J. Noble, Judith Widdowson, J. Seckl
1997Brain Research. Molecular Brain Research98 citations
Semantic Scholar
The effect of adrenalectomy on 5-hydroxytryptamine and corticosteroid receptor subtype messenger RNA expression in rat hippocampus.
M. C. Holmes, J. Yau, K. French, J. Seckl
1995Neuroscience96 citations
Semantic Scholar
Local amplification of glucocorticoids in the aging brain and impaired spatial memory
J. Yau, J. Seckl
2012Front. Ag. Neurosci.92 citations Open access
Semantic Scholar
Acute restraint stress increases 5-HT7 receptor mRNA expression in the rat hippocampus.
J. Yau, J. Noble, J. Seckl
2001Neuroscience Letters79 citations
Semantic Scholar
Continuous blockade of brain mineralocorticoid receptors impairs spatial learning in rats.
J. Yau, J. Noble, J. Seckl
1999Neuroscience Letters76 citations
Semantic Scholar
11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics.
T. Sandeep, J. Yau, Alasdair M. J. MacLullich, J. Noble +3 more
2004Proceedings of the National Academy of Sciences of the United States of America75 citations
Semantic Scholar
Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture.
M. Lai, James A. McCormick, K. Chapman, P. Kelly +2 more
2003Neuroscience73 citations
Semantic Scholar
11β-Hydroxysteroid Dehydrogenase Type 1 Deficiency Prevents Memory Deficits with Aging by Switching from Glucocorticoid Receptor to Mineralocorticoid Receptor-Mediated Cognitive Control
J. Yau, J. Noble, J. Seckl
2011Journal of Neuroscience68 citations Open access
Semantic Scholar
11 Beta-hydroxysteroid dehydrogenases in the brain: two enzymes two roles.
M. Holmes, J. Yau, Y. Kotelevtsev, J. Mullins +1 more
2003Annals of the New York Academy of Sciences57 citations
Semantic Scholar
The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats.
J. Yau, C. Hibberd, J. Noble, J. Seckl
2002Brain Research. Molecular Brain Research57 citations
Semantic Scholar
Cognitive and disease-modifying effects of 11ß-hydroxysteroid dehydrogenase type 1 inhibition in male Tg2576 mice, a model of Alzheimer's disease
K. Sooy, J. Noble, A. Mcbride, M. Binnie +5 more
201554 citations
Semantic Scholar
11β‐Hydroxysteroid Dehydrogenases in the Brain
M. C. Holmes, J. Yau, Y. Kotelevtsev, J. Mullins +1 more
200351 citations
Semantic Scholar
Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin.
J. Yau, J. Noble, J. Seckl
1997Neuroscience51 citations
Semantic Scholar
Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice
J. Yau, Nicola Wheelan, J. Noble, B. Walker +4 more
2015Neurobiology of Aging50 citations Open access
Semantic Scholar
The Antidepressant Desipramine Requires the ABCB1 (Mdr1)-Type p-Glycoprotein to Upregulate the Glucocorticoid Receptor in Mice
J. Yau, J. Noble, Sarah Thomas, R. Kerwin +4 more
2007Neuropsychopharmacology47 citations
Semantic Scholar
11 beta-Hydroxysteroid dehydrogenase in the rat ovary: high expression in the oocyte.
R. Benediktsson, J. Yau, S. Low, L. Brett +3 more
1992Journal of Endocrinology47 citations
Semantic Scholar
Chronic 3,4-methylenedioxymethamphetamine administration decreases glucocorticoid and mineralocorticoid receptor, but increases 5-hydroxytryptamine1C receptor gene expression in the rat hippocampus.
J. Yau, P. A. Kelly, J. Sharkey, J. Seckl
1994Neuroscience45 citations
Semantic Scholar
Short-term administration of fluoxetine and venlafaxine decreases corticosteroid receptor mRNA expression in the rat hippocampus.
J. Yau, J. Noble, C. Hibberd, J. Seckl
2001Neuroscience Letters42 citations
Semantic Scholar
Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl₂: hippocampal signal enhancement without disruption of hippocampus-dependent behavior.
Stewart J. Jackson, Rosalind Hussey, M. Jansen, Gavin D. Merrifield +4 more
2011Behavioural Brain Research39 citations
Semantic Scholar
Obese Zucker rats have reduced mineralocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type 1 expression in hippocampus-implications for dysregulation of the hypothalamic-pituitary-adrenal axis in obesity.
C. Mattsson, M. Lai, J. Noble, Eoin F. McKinney +3 more
2003Endocrinology39 citations Open access
Semantic Scholar
Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning.
R. Sarabdjitsingh, Ming Zhou, J. Yau, Scott P. Webster +4 more
2014Neuropharmacology38 citations Open access
Semantic Scholar
Decreased NGFI-A gene expression in the hippocampus of cognitively impaired aged rats.
J. Yau, Tommy Olsson, R. G. Morris, J. Noble +1 more
1996Brain Research. Molecular Brain Research36 citations
Semantic Scholar
Central 6-hydroxydopamine lesions decrease mineralocorticoid, but not glucocorticoid receptor gene expression in the rat hippocampus.
J. Yau, J. Seckl
1992Neuroscience Letters34 citations
Semantic Scholar
Medial septal cholinergic lesions increase hippocampal mineralocorticoid and glucocorticoid receptor messenger RNA expression.
J. Yau, R. C. Dow, G. Fink, J. Seckl
1992Brain Research33 citations
Semantic Scholar
Hippocampal corticosteroid receptor mRNA expression and spatial learning in the aged Wistar rat.
J. Yau, R. Morris, J. Seckl
1994Brain Research32 citations
Semantic Scholar
Short-term inhibition of 11-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice
Nicola Wheelan, S. Webster, C. Kenyon, S. Caughey +4 more
201531 citations
Semantic Scholar
Decreased Npas4 and Arc mRNA Levels in the Hippocampus of Aged Memory‐Impaired Wild‐Type But Not Memory Preserved 11β‐HSD1 Deficient Mice
Jing Qiu, D. R. Dunbar, J. Noble, Carolynn Cairns +5 more
2016Journal of neuroendocrinology30 citations Open access
Semantic Scholar
11β-HYDROXYSTEROID DEHYDROGENASES: A NOVEL CONTROL OF GLUCOCORTICOID ACTION IN THE BRAIN
J. Seckl, J. Yau, M. Holmes
200230 citations
Semantic Scholar
Serotonin receptor subtype gene expression in the hippocampus of aged rats following chronic amitriptyline treatment.
J. Yau, Tommy Olsson, J. Noble, J. Seckl
1999Brain Research. Molecular Brain Research30 citations
Semantic Scholar
Central Administration of a Cytochrome P450-7B Product 7α-Hydroxypregnenolone Improves Spatial Memory Retention in Cognitively Impaired Aged Rats
J. Yau, J. Noble, M. Graham, J. Seckl
2006Journal of Neuroscience29 citations Open access
Semantic Scholar
11β-hydroxysteroid dehydrogenase type I in the brain; thickening the glucocorticoid soup
J. Yau, J. Seckl
2001Molecular Psychiatry28 citations
Semantic Scholar
Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine.
J. Yau, J. Noble, K. Chapman, J. Seckl
2004Brain Research. Molecular Brain Research26 citations
Semantic Scholar
Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats
A. Him, A. Johnston, J. Yau, J. Seckl +1 more
2001NeuroReport24 citations
Semantic Scholar
Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids
Nicola Wheelan, C. Kenyon, Anjanette P. Harris, Carolynn Cairns +3 more
2018Psychoneuroendocrinology23 citations Open access
Semantic Scholar
Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease
K. Sooy, J. Noble, Andrew McBride, M. Binnie +4 more
2015Endocrinology22 citations Open access
Semantic Scholar

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J. Seckl×9
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M. Meaney — researcher profile on SciRah