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M. Edin · SciRah

Researcher profile · Semantic Scholar

M. Edin

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M. Edin — researcher profile on SciRah

h-index: 47
Works: 164
Citations: 6,016

Most-cited papers

CYP450-derived oxylipins mediate inflammatory resolution
D. Gilroy, M. Edin, R. D. De Maeyer, J. Bystrom +5 more
2016Proceedings of the National Academy of Sciences of the United States of America143 citations Open access
Semantic Scholar
Metabolic reprogramming through fatty acid transport protein 1 (FATP1) regulates macrophage inflammatory potential and adipose inflammation
A. Johnson, Yuanyuan Qin, A. Cozzo, A. Freemerman +17 more
2016Molecular Metabolism123 citations Open access
Semantic Scholar
Vascular Actions of 20-HETE
Samantha L. Hoopes, V. Garcia, M. Edin, M. Schwartzman +1 more
2015Prostaglandins & other lipid mediators118 citations Open access
Semantic Scholar
Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia
M. Edin, Behin Gholipour Hamedani, A. Gruzdev, Joan P. Graves +9 more
2018Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis
Weicang Wang, Jun Yang, M. Edin, Yu-Xin Wang +20 more
2019Cancer Research70 citations Open access
Semantic Scholar
Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis
Yan Gong, Z. Shao, Z. Fu, M. Edin +11 more
2016EBioMedicine69 citations Open access
Semantic Scholar
Sinus surgery is associated with a decrease in aspirin-induced reaction severity in AERD patients
E. Jerschow, M. Edin, Yu-Ling Chi, Beth Hurst +16 more
2018Journal of Allergy and Clinical Immunology: In Practice62 citations Open access
Semantic Scholar
Aspirin inhibits the production of proangiogenic 15(S)-HETE by platelet cyclooxygenase-1
F. Rauzi, Nicholas S. Kirkby, M. Edin, J. Whiteford +3 more
2016The FASEB Journal52 citations Open access
Semantic Scholar
Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study[S]
A. Oni-Orisan, M. Edin, J. A. Lee, Michael A. Wells +9 more
2016Journal of Lipid Research50 citations Open access
Semantic Scholar
Good or bad: Application of RAAS inhibitors in COVID-19 patients with cardiovascular comorbidities
J. J. Wang, M. Edin, D. Zeldin, Chen-Ze Li +2 more
2020Pharmacology and Therapeutics49 citations Open access
Semantic Scholar
Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry
N. Schebb, N. Kampschulte, G. Hagn, Kathrin Plitzko +91 more
2025Science Signaling47 citations Open access
Semantic Scholar
Proteome and functional decline as platelets age in the circulation
Harriet E. Allan, Melissa A. Hayman, S. Marcone, M. Chan +9 more
2021bioRxiv46 citations Open access
Semantic Scholar
Cytochrome P450 oxidase 2C inhibition adds to ω-3 long-chain polyunsaturated fatty acids protection against retinal and choroidal neovascularization
Yan Gong, Z. Fu, M. Edin, Chi-Hsiu Liu +15 more
2016Arteriosclerosis, Thrombosis and Vascular Biology45 citations Open access
Semantic Scholar
Inflammation and oxidative stress as mediators of the impacts of environmental exposures on human pregnancy: Evidence from oxylipins
B. Welch, E. McNell, M. Edin, K. Ferguson
2022Pharmacology and Therapeutics43 citations
Semantic Scholar
Role of Linoleic Acid-Derived Oxylipins in Cancer
M. Edin, C. Duval, Guodong Zhang, D. Zeldin
2020Cancer Metastasis Review39 citations Open access
Semantic Scholar
Plasma 15-hydroxyeicosatetraenoic acid predicts treatment outcomes in aspirin-exacerbated respiratory disease
E. Jerschow, M. Edin, T. Pelletier, W. Abuzeid +13 more
2017Journal of Allergy and Clinical Immunology: In Practice39 citations Open access
Semantic Scholar
Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization
Eiichi Hasegawa, Saori Inafuku, L. Mulki, Y. Okunuki +15 more
2017Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis
Joan P. Graves, A. Gruzdev, J. Bradbury, Laura M. DeGraff +2 more
2017Drug Metabolism And Disposition35 citations Open access
Semantic Scholar
Pre-diagnostic serum levels of fatty acid metabolites and risk of ovarian cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial.
M. Hada, M. Edin, P. Hartge, Fred B. Lih +3 more
2018Cancer Epidemiology, Biomarkers and Prevention34 citations Open access
Semantic Scholar
Deficiency of Soluble Epoxide Hydrolase Protects Cardiac Function Impaired by LPS-Induced Acute Inflammation
V. Samokhvalov, K. Jamieson, Ahmed M. Darwesh, H. Keshavarz-Bahaghighat +5 more
2019Frontiers in Pharmacology32 citations Open access
Semantic Scholar
Characterization of the Cytochrome P450 Epoxyeicosanoid Pathway in Non-alcoholic Steatohepatitis
M. A. Wells, Kimberly C. Vendrov, M. Edin, B. Ferslew +9 more
2016Prostaglandins & other lipid mediators29 citations Open access
Semantic Scholar
sEH promotes macrophage phagocytosis and lung clearance of Streptococcus pneumoniae.
Hong Li, J. Bradbury, M. Edin, Joan P. Graves +8 more
2021Journal of Clinical Investigation28 citations Open access
Semantic Scholar
Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M
J. Mitchell, Rebecca B. M. Knowles, Nicholas S. Kirkby, D. M. Reed +8 more
2018Circulation Research28 citations Open access
Semantic Scholar
Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis
Nicholas S. Kirkby, J. Raouf, B. Ahmetaj-Shala, Bin Liu +11 more
2019Cardiovascular Research26 citations Open access
Semantic Scholar
Effect of Soluble Epoxide Hydrolase on the Modulation of Coronary Reactive Hyperemia: Role of Oxylipins and PPARγ
Ahmad Hanif, M. Edin, D. Zeldin, C. Morisseau +1 more
2016PLoS ONE26 citations Open access
Semantic Scholar
Multi-tissue profiling of oxylipins reveal a conserved up-regulation of epoxide:diol ratio that associates with white adipose tissue inflammation and liver steatosis in obesity
Charlotte Hateley, Antoni Olona, Laura Halliday, M. Edin +14 more
2024EBioMedicine24 citations Open access
Semantic Scholar
Soluble Epoxide Hydrolase Deficiency Attenuates Lipotoxic Cardiomyopathy via Upregulation of AMPK-mTORC Mediated Autophagy
Lu-Yun Wang, Da-Qiang Zhao, Liang-Qiu Tang, Huihui Li +12 more
2020Journal of Molecular and Cellular Cardiology24 citations Open access
Semantic Scholar
Epoxide hydrolase 3 (Ephx3) gene disruption reduces ceramide linoleate epoxide hydrolysis and impairs skin barrier function
M. Edin, Haruto Yamanashi, W. Boeglin, Joan P. Graves +4 more
2020Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Contribution of alveolar type II cell‐derived cyclooxygenase‐2 to basal airway function, lung inflammation, and lung fibrosis
Jennifer Cheng, Ryan T. Dackor, J. Bradbury, G. Li +10 more
2016The FASEB Journal23 citations Open access
Semantic Scholar
Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation
Joan P. Graves, A. Gruzdev, J. Bradbury, Laura M. DeGraff +5 more
2015Drug Metabolism And Disposition22 citations Open access
Semantic Scholar
Expression of Cyp2c/Cyp2j subfamily members and oxylipin levels during LPS‐induced inflammation and resolution in mice
Joan P. Graves, J. Bradbury, A. Gruzdev, Hong Li +4 more
2019The FASEB Journal21 citations Open access
Semantic Scholar
LPS potentiates insulin-driven hypoglycemic shock
J. Hagar, M. Edin, Fred B. Lih, Lance R. Thurlow +4 more
2017Journal of Immunology21 citations Open access
Semantic Scholar
CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid
Jianan Zhang, Jun Yang, C. Duval, M. Edin +22 more
2023The FASEB Journal18 citations Open access
Semantic Scholar
Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis
Antoni Olona, Ximena Terra, J. Ko, Carme Grau-Bové +11 more
2018Molecular Metabolism18 citations Open access
Semantic Scholar
Deletion of soluble epoxide hydrolase enhances coronary reactive hyperemia in isolated mouse heart: role of oxylipins and PPARγ.
Ahmad Hanif, M. Edin, D. Zeldin, C. Morisseau +1 more
2016American Journal of Physiology. Regulatory Integrative and Comparative Physiology18 citations Open access
Semantic Scholar
Increased Perfluorooctanesulfonate (PFOS) Toxicity and Accumulation Is Associated with Perturbed Prostaglandin Metabolism and Increased Organic Anion Transport Protein (OATP) Expression
Lanie A Williams, Matthew Hamilton, M. Edin, Fred B. Lih +4 more
2024Toxics17 citations Open access
Semantic Scholar
Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice
Samantha L. Hoopes, A. Gruzdev, M. Edin, Joan P. Graves +5 more
2017PLoS ONE17 citations Open access
Semantic Scholar
TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation
Hong Li, J. Bradbury, M. Edin, A. Gruzdev +11 more
2024Journal of Clinical Investigation16 citations Open access
Semantic Scholar
Regulation of cardiovascular biology by microsomal epoxide hydrolase
M. Edin, D. Zeldin
2021Toxicological Research16 citations Open access
Semantic Scholar
Sex- and Isoform-Specific Mechanism of Neuroprotection by Transgenic Expression of P450 Epoxygenase in Vascular Endothelium
J. Jia, C. Davis, Wenri H. Zhang, M. Edin +11 more
2016Experimental Neurology16 citations Open access
Semantic Scholar
Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids
M. Edin, Fred B. Lih, B. Hammock, S. Thomson +2 more
2020Cells15 citations Open access
Semantic Scholar
Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin
M. Crescente, P. Armstrong, Nicholas S. Kirkby, M. Edin +12 more
2020The FASEB Journal14 citations Open access
Semantic Scholar
Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice
Ahmad Hanif, M. Edin, D. Zeldin, C. Morisseau +2 more
2017PLoS ONE14 citations Open access
Semantic Scholar
Vascular Endothelial Over-Expression of Human Soluble Epoxide Hydrolase (Tie2-sEH Tr) Attenuates Coronary Reactive Hyperemia in Mice: Role of Oxylipins and ω-Hydroxylases
Ahmad Hanif, M. Edin, D. Zeldin, C. Morisseau +2 more
2017PLoS ONE13 citations Open access
Semantic Scholar
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury
K. Jamieson, Ahmed M. Darwesh, Deanna K. Sosnowski, Hao Zhang +9 more
2021International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Disruption of Ephx2 in cardiomyocytes but not endothelial cells improves functional recovery after ischemia-reperfusion in isolated mouse hearts
M. Edin, A. Gruzdev, J. Bradbury, Joan P. Graves +4 more
2023Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins
S. Thomson, M. Edin, Fred B. Lih, Michael Davies +5 more
2015Biochemical and Biophysical Research Communications - BBRC11 citations Open access
Semantic Scholar
Cytochrome P450 oxidase 2J inhibition suppresses choroidal neovascularization in mice
Yan Gong, Yohei Tomita, M. Edin, Anli Ren +7 more
2022Metabolism: Clinical and Experimental10 citations Open access
Semantic Scholar
Identification of a homozygous recessive variant in PTGS1 resulting in a congenital aspirin-like defect in platelet function
M. Chan, Melissa A. Hayman, S. Sivapalaratnam, M. Crescente +21 more
2020Haematologica10 citations Open access
Semantic Scholar
Cardioprotective effect of 19,20-epoxydocosapentaenoic acid (19,20-EDP) in ischaemic injury involves direct activation of mitochondrial sirtuin 3
Ahmed M. Darwesh, Liye Fang, T. Altamimi, K. Jamieson +17 more
2024Cardiovascular Research9 citations
Semantic Scholar

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