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A. Webb · SciRah

Researcher profile · Semantic Scholar

A. Webb

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A. Webb — researcher profile on SciRah

h-index: 48
Works: 133
Citations: 8,785

Most-cited papers

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
J. Hildebrand, M. Tanzer, I. Lucet, S. Young +16 more
2014Proceedings of the National Academy of Sciences of the United States of America578 citations Open access
Semantic Scholar
CIS is a potent checkpoint in NK cell–mediated tumor immunity
Rebecca B Delconte, T. B. Kolesnik, L. Dagley, J. Rautela +28 more
2016Nature Immunology348 citations
Semantic Scholar
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
S. Masters, V. Lagou, I. Jéru, P. Baker +28 more
2016Science Translational Medicine285 citations Open access
Semantic Scholar
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
E. Petrie, J. Sandow, Annette V. Jacobsen, Brian J. Smith +15 more
2018Nature Communications174 citations Open access
Semantic Scholar
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
Jaclyn S. Pearson, Cristina Giogha, S. Mühlen, U. Nachbur +19 more
2017Nature Microbiology174 citations Open access
Semantic Scholar
VDAC2 enables BAX to mediate apoptosis and limit tumor development
Hui-San Chin, Mark Li, I. Tan, R. Ninnis +23 more
2018Nature Communications171 citations Open access
Semantic Scholar
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
S. Hogg, Olga Motorna, L. Cluse, Timothy M. Johanson +38 more
2021Molecules and Cells156 citations Open access
Semantic Scholar
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
U. Nachbur, Che Stafford, Aleksandra Bankovacki, Y. Zhan +24 more
2015Nature Communications139 citations Open access
Semantic Scholar
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
J. Le Nours, N. Gherardin, Sri H. Ramarathinam, W. Awad +31 more
2019Science129 citations
Semantic Scholar
Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood.
Yi Ju, Hannah G. Kelly, L. Dagley, A. Reynaldi +12 more
2020ACS Nano106 citations Open access
Semantic Scholar
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.
E. Petrie, J. Sandow, Wil I. L. Lehmann, L. Liang +15 more
2019Cell Reports105 citations Open access
Semantic Scholar
Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase
A. Seidi, Linden S Muellner-Wong, Esther Rajendran, Edwin T. Tjhin +6 more
2018eLife103 citations Open access
Semantic Scholar
Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography
Andrew D. Foers, S. Chatfield, L. Dagley, Benjamin J Scicluna +5 more
2018Journal of Extracellular Vesicles103 citations Open access
Semantic Scholar
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.
M. Tanzer, Anne Tripaydonis, A. Webb, S. Young +6 more
2015Biochemical Journal97 citations
Semantic Scholar
RIPLET, and not TRIM25, is required for endogenous RIG‐I‐dependent antiviral responses
T. Hayman, A. Hsu, T. B. Kolesnik, L. Dagley +14 more
2019Immunology and Cell Biology95 citations
Semantic Scholar
Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
W. Wong, Rick K. Huang, Sébastien Menant, C. Hong +17 more
2018Nature91 citations
Semantic Scholar
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
Sarah E. Garnish, Y. Meng, A. Koide, J. Sandow +15 more
2021Nature Communications90 citations Open access
Semantic Scholar
The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation
S. Vijayaraj, R. Feltham, M. Rashidi, Daniel Frank +12 more
2021Nature Communications84 citations Open access
Semantic Scholar
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
E. Petrie, R. Birkinshaw, A. Koide, E. Denbaum +14 more
2020Proceedings of the National Academy of Sciences of the United States of America83 citations Open access
Semantic Scholar
Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.
Alessandro D. Uboldi, J. McCoy, M. Blume, M. Gerlic +10 more
2015Cell Host and Microbe82 citations Open access
Semantic Scholar
Cytotoxic T cells swarm by homotypic chemokine signalling
J. L. Galeano Niño, Sophie V. Pageon, Szun S. Tay, Feyza Colakoglu +19 more
2020eLife78 citations Open access
Semantic Scholar
Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
M. Stutz, S. Ojaimi, C. Allison, Simon P. Preston +7 more
2017Cell Death and Differentiation78 citations Open access
Semantic Scholar
Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling
L. Kedzierski, Michelle D. Tate, A. Hsu, T. B. Kolesnik +18 more
2017eLife75 citations Open access
Semantic Scholar
Oligomerization-driven MLKL ubiquitylation antagonises necroptosis
Zi-Kou Liu, L. Dagley, K. Shield-Artin, S. Young +13 more
2021bioRxiv69 citations Open access
Semantic Scholar
ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism
S. T. Boyle, V. Poltavets, Jasreen Kular, Natasha T. Pyne +14 more
2020Nature Cell Biology67 citations
Semantic Scholar
Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems
Christian M. Harding, M. R. Pulido, Gisela Di Venanzio, Rachel L. Kinsella +4 more
2017Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
Alessandro D. Uboldi, Mary-Louise Wilde, Emily McRae, R. J. Stewart +11 more
2018bioRxiv62 citations Open access
Semantic Scholar
BAK core dimers bind lipids and can be bridged by them
A. Cowan, N. A. Smith, J. Sandow, E. Kapp +14 more
2020Nature Structural & Molecular Biology60 citations
Semantic Scholar
The Cellular Redox Environment Alters Antigen Presentation*
Jonathan A. Trujillo, N. Croft, Nadine L. Dudek, R. Channappanavar +10 more
2014Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics.
L. Dagley, Giuseppe Infusini, Rune H Larsen, J. Sandow +1 more
2019Journal of Proteome Research57 citations
Semantic Scholar
Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte
Danushka S. Marapana, L. Dagley, J. Sandow, T. Nebl +8 more
2018Nature Microbiology57 citations
Semantic Scholar
Therapeutic blockade of Activin-A improves NK cell function and anti-tumor immunity
J. Rautela, L. Dagley, I. Schuster, S. Hediyeh-zadeh +12 more
2018bioRxiv54 citations Open access
Semantic Scholar
Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii
M. Coffey, L. Dagley, Simona Seizova, E. Kapp +5 more
2018mBio53 citations Open access
Semantic Scholar
BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association.
M. Dengler, A. Robin, L. Gibson, Mark Li +6 more
2019Cell Reports51 citations Open access
Semantic Scholar
The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD)
Nichollas E. Scott, Cristina Giogha, Georgina L Pollock, C. Kennedy +4 more
2017Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine
J. Sandow, A. Rainczuk, Giuseppe Infusini, Ming Y. Makanji +9 more
2018PROTEOMICS - Clinical Applications48 citations Open access
Semantic Scholar
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
M. V. van Delft, Stephane Chappaz, Yelena Khakham, C. Bui +32 more
2019Nature Chemical Biology46 citations
Semantic Scholar
How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
Yibin Xu, N. S. Kirk, Hari Venugopal, M. Margetts +6 more
2020Structure44 citations Open access
Semantic Scholar
Ensemble Properties of Bax Determine Its Function.
A. Robin, S. Iyer, R. Birkinshaw, J. Sandow +7 more
2018Structure44 citations Open access
Semantic Scholar
Proteomic analysis of extracellular vesicles reveals an immunogenic cargo in rheumatoid arthritis synovial fluid
Andrew D. Foers, L. Dagley, S. Chatfield, A. Webb +4 more
2020Clinical & Translational Immunology35 citations Open access
Semantic Scholar
Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation.
Sarah G. Paule, Sophea Heng, N. Samarajeewa, Ying Li +11 more
2021Human Reproduction33 citations Open access
Semantic Scholar
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
Y. Lim, Dylan De Bellis, J. Sandow, Luisa Capalbo +5 more
2020bioRxiv30 citations Open access
Semantic Scholar
Idiopathic infertility in women is associated with distinct changes in proliferative phase uterine fluid proteins†
Harriet C. Fitzgerald, J. Evans, N. Johnson, Giuseppe Infusini +5 more
2018Biology of Reproduction28 citations
Semantic Scholar
Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair
J. Evans, Giuseppe Infusini, J. McGovern, L. Cuttle +8 more
2018The FASEB Journal28 citations Open access
Semantic Scholar
Dynamic reconfiguration of pro‐apoptotic BAK on membranes
J. Sandow, I. Tan, A. S. Huang, S. Masaldan +11 more
2021EMBO Journal26 citations Open access
Semantic Scholar
Therapeutic blockade of activin-A improves NK cell function and antitumor immunity
J. Rautela, L. Dagley, C. De Oliveira, I. Schuster +13 more
2019Science Signaling26 citations Open access
Semantic Scholar
MsImpute: Estimation of Missing Peptide Intensity Data in Label-Free Quantitative Mass Spectrometry
S. Hediyeh-zadeh, A. Webb, Melissa J. Davis
2023Molecular & Cellular Proteomics25 citations Open access
Semantic Scholar
Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death
Lin Liu, J. Sandow, D. L. Leslie Pedrioli, A. Samson +15 more
2022Science Advances23 citations Open access
Semantic Scholar
Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation
Natalie J Foot, Macarena B. Gonzalez, Kelly M. Gembus, P. Fonseka +7 more
2021Journal of Extracellular Vesicles22 citations Open access
Semantic Scholar
Role of salt bridges in the dimer interface of 14-3-3ζ in dimer dynamics, N-terminal α-helical order, and molecular chaperone activity
J. Woodcock, Katy L Goodwin, J. Sandow, C. Coolen +5 more
2017Journal of Biological Chemistry22 citations Open access
Semantic Scholar

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