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D. Felsing · SciRah

Researcher profile · Semantic Scholar

D. Felsing

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D. Felsing — researcher profile on SciRah

h-index: 11
Works: 28
Citations: 243

Most-cited papers

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models.
Clinton E. Canal, D. Felsing, Yue Liu, Wan-Ying Zhu +4 more
2015ACS Chemical Neuroscience38 citations
Semantic Scholar
Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction
D. Felsing, Noelle C. Anastasio, J. Miszkiel, S. Gilbertson +2 more
2018PLoS ONE28 citations Open access
Semantic Scholar
A Novel Aminotetralin-Type Serotonin (5-HT) 2C Receptor-Specific Agonist and 5-HT2A Competitive Antagonist/5-HT2B Inverse Agonist with Preclinical Efficacy for Psychoses
Clinton E. Canal, D. Morgan, D. Felsing, Krishnakanth Kondabolu +4 more
2014Journal of Pharmacology and Experimental Therapeutics25 citations Open access
Semantic Scholar
Maternal Opioid Exposure Culminates in Perturbed Murine Neurodevelopment and Hyperactive Phenotype in Adolescence
Caitlin R. Schlagal, Tiffany J. Dunn, Pei Xu, D. Felsing +9 more
2021Neuroscience23 citations Open access
Semantic Scholar
Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics
D. Felsing, M. Jain, John A. Allen
2019Current Topics in Medicinal Chemistry23 citations Open access
Semantic Scholar
Discovery of Potent and Brain-Penetrant GPR52 Agonist that Suppresses Psychostimulant Behavior
Ping-Yuan Wang, D. Felsing, Hai-Ying Chen, S. Stutz +4 more
2020Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists.
Ping-Yuan Wang, D. Felsing, Hai-Ying Chen, Sweta R. Raval +2 more
2019ACS Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Synthesis of novel 5-substituted-2-aminotetralin analogs: 5-HT1A and 5-HT7 G protein-coupled receptor affinity, 3D-QSAR and molecular modeling.
Charles K. Perry, Austen B. Casey, D. Felsing, Rajender Vemula +6 more
2019Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
Small‐Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models
Catherine M. Sampson, James M. Kasper, D. Felsing, Sweta R. Raval +7 more
2018Pharmacology Research & Perspectives14 citations Open access
Semantic Scholar
Evaluation of Lorcaserin as an Anticonvulsant in Juvenile Fmr1 Knockout Mice
Tanishka S. Saraf, D. Felsing, J. Armstrong, R. Booth +1 more
2021Epilepsy Research13 citations Open access
Semantic Scholar
Ligand-directed serotonin 5-HT2C receptor desensitization and sensitization
D. Felsing, Clinton E. Canal, R. Booth
2019European Journal of Pharmacology13 citations Open access
Semantic Scholar
Discovery of 3-((4-Benzylpyridin-2-yl)amino)benzamides as Potent GPR52 G Protein-Biased Agonists
Ryan E. Murphy, Ping-Yuan Wang, Saghir Ali, Hudson R. Smith +4 more
2024Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
Retraction of "Synthesis and Pharmacological Evaluation of Noncatechol G Protein Biased and Unbiased Dopamine D1 Receptor Agonists".
Ping-Yuan Wang, D. Felsing, Hai-Ying Chen, Sweta R. Raval +2 more
2022ACS Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
Functionally selective dopamine D1 receptor endocytosis and signaling by catechol and non-catechol agonists
Ashley N. Nilson, D. Felsing, Ping-Yuan Wang, Manish K. Jain +2 more
2025Biochemistry1 citations Open access
Semantic Scholar
Functionally selective dopamine D1 receptor endocytosis and signaling by catechol and non-catechol agonists
Ashley N. Nilson, D. Felsing, Ping-Yuan Wang, Manish K. Jain +2 more
2024bioRxiv1 citations Open access
Semantic Scholar
β-Arrestins Mediate Rapid 5-HT2A Receptor Endocytosis to Control the Efficacy and Kinetics of Serotonin and Psychedelic Hallucinogen Signaling
Hudson R. Smith, D. Felsing, A. Nilson, J. Allen
2023Neuropharmacology1 citations Open access
Semantic Scholar
Bi‐directional cAMP signaling crosstalk between dopamine D2 receptors and the constitutively active orphan receptor GPR52
Ryan E. Murphy, D. Felsing, John Allen
2021The FASEB Journal1 citations Open access
Semantic Scholar
Heterocyclic G protein-coupled receptor 52 (GPR52) agonists
Jia Zhou, John A. Allen, Ping-Yuan Wang, D. Felsing
20201 citations
Semantic Scholar
Homology Modeling Inspired Synthesis of 5-HT2A Receptor Inhibitors: A Diazepine Analogue of the Atypical Antipsychotic JL13.
Enrico Mongeau, Geng-Yang Yuan, Zachary Minden, S. Waldron +4 more
2017Central Nervous System Agents in Medicinal Chemistry1 citations
Semantic Scholar
Discovery of an Allosteric Agonist for Schizophrenia Risk Gene GPR52 with Antipsychotic Activity
Ryan E. Murphy, D. Felsing, Nolan M. Dvorak, F. Laezza +2 more
2023Neuropharmacology0 citations Open access
Semantic Scholar
Structure Activity Relationships of Novel GPR52 Agonists that Suppress Psychostimulant Behavior
D. Felsing, Ping-Yuan Wang, Ryan E. Murphy, Jia Zhou +1 more
2021The FASEB Journal0 citations
Semantic Scholar
CRISPR/Cas9‐mediated knockout of G proteins and β‐arrestins defines their specific but interdependent roles in dopamine D1 receptor signaling
M. Jain, Ashely N. Nilson, D. Felsing, A. Inoue +1 more
2021The FASEB Journal0 citations
Semantic Scholar
Drug Discovery Targeting Serotonin G Protein-Coupled Receptors in the Treatment of Neuropsychiatric Disorders
D. Felsing
20160 citations
Semantic Scholar
Erratum: An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models (ACS Chemical Neuroscience (2015) 6:7 (1259-1270) (DOI:10.1021/acschemneuro.5b00099)
Clinton E. Canal, D. Felsing, Yue Liu, Wan-Ying Zhu +4 more
20150 citations
Semantic Scholar
Correction to an orally active phenylaminotetralin-chemotype serotonin 5-HT7 and 5-HT1A receptor partial agonist that corrects motor stereotypy in mouse models.
Clinton E. Canal, D. Felsing, Yue Liu, Wan-Ying Zhu +4 more
2015ACS Chemical Neuroscience0 citations
Semantic Scholar
A novel 5HT2 modulator as a potential antipsychotic medication
D. Morgan, Krishnakanth Kondabolu, C. Ajufo, P. Orza +7 more
20140 citations
Semantic Scholar
Correction to “A Novel Aminotetralin-Type Serotonin (5-HT) 2C Receptor-Specific Agonist and 5-HT2A Competitive Antagonist/5-HT2B Inverse Agonist with Preclinical Efficacy for Psychoses”
Clinton E. Canal, Drake Morgan, D. Felsing, Krishnakanth Kondabolu +4 more
2014Journal of Pharmacology and Experimental Therapeutics0 citations Open access
Semantic Scholar
Development of novel serotonin 7‐targeting compounds based on the 2‐dimethylaminotetralin scaffold (1059.13)
Clinton E. Canal, D. Felsing, Wan-Ying Zhu, Yue Liu +2 more
20140 citations
Semantic Scholar

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Ping-Yuan Wang×8
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Ryan E. Murphy×5

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