Donglei Liu

Most-cited papers

1. The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration.

   C. Adams, K. Anderson, G. Artman, J. Bizec +31 more

   2018Journal of Medicinal Chemistry35 citations Open access

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2. Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration.

   E. Meredith, N. Mainolfi, Stephen H Poor, Yubin Qiu +25 more

   2015Journal of Medicinal Chemistry28 citations Open access

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3. Structure-based design and pre-clinical characterization of selective and orally bioavailable Factor XIa inhibitors: Demonstrating the power of an integrated S1 protease family approach.

   E. Lorthiois, James Roache, David Barnes-Seeman, E. Altmann +51 more

   2020Journal of Medicinal Chemistry19 citations Open access

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4. Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.

   R. Karki, J. Powers, N. Mainolfi, K. Anderson +24 more

   2019Journal of Medicinal Chemistry14 citations Open access

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5. The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma.

   T. Ehara, C. Adams, Douglas E Bevan, N. Ji +17 more

   2018Journal of Medicinal Chemistry12 citations

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6. MiR‐223‐3p affects the proliferation and apoptosis of HCAECs in Kawasaki disease by regulating the expression of FOXP3

   Ronghao Zheng, Jing Xie, Weijie Li, Jianping Shang +12 more

   2023Immunity, Inflammation and Disease8 citations Open access

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7. Syntheses of 1-Substituted-3-aminopyrazoles.

   Nan Ji, E. Meredith, Donglei Liu, C. Adams +6 more

   20117 citations

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8. One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC)

   G. Artman, Catherine Solovay, C. Adams, Diaz Brian +15 more

   20106 citations

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9. Sulfoximines as Secondary Sulfonamide Isosteres: Paradoxical Impact on Solubility and Plasma Protein Binding.

   S. M. King, Ming Qian, Will Sii Hong Lau, Cristian Draghici +13 more

   2026Journal of Medicinal Chemistry2 citations

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10. A Method to Determine the Safe Time for High Waxy Crude Pipeline With Uncertainty

    Bo Xu, Qing Miao, H. Lan, Yan Feng +1 more

    20121 citations

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11. Two Unusual Phenyl Derivatives from Pathogen-Infected Solanum tuberosum with Antifungal Activity

    Liang-Yan Liu, Jun Han, Yong Shen, Yanglu Li +2 more

    2018Chemistry of Natural Compounds0 citations

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12. Two Unusual Phenyl Derivatives from Pathogen-Infected Solanum tuberosum with Antifungal Activity

    Liang-Yan Liu, Jun Han, Yong Shen, Yanglu Li +2 more

    2018Chemistry of Natural Compounds0 citations

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13. Title Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration

    Nello Mainol, Stephen H Poor, Yubin Qiu, K. Miranda +25 more

    20180 citations

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