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H. Kitao · SciRah

Researcher profile · Semantic Scholar

H. Kitao

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H. Kitao — researcher profile on SciRah

h-index: 35
Works: 114
Citations: 3,674

Most-cited papers

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
M. Ishiai, H. Kitao, A. Smogorzewska, Junya Tomida +9 more
2008Nature Structural &Molecular Biology253 citations Open access
Semantic Scholar
Emergence of epidermal growth factor receptor T790M mutation during chronic exposure to gefitinib in a non small cell lung cancer cell line.
Atsuko Ogino, H. Kitao, Seiki Hirano, A. Uchida +6 more
2007Cancer Research180 citations
Semantic Scholar
Vimentin as a poor prognostic factor for triple-negative breast cancer
N. Yamashita, E. Tokunaga, H. Kitao, Yuichi Hisamatsu +6 more
2013Journal of Cancer Research and Clinical Oncology148 citations Open access
Semantic Scholar
DNA replication stress and cancer chemotherapy
H. Kitao, Makoto Iimori, Y. Kataoka, T. Wakasa +4 more
2017Cancer Science99 citations Open access
Semantic Scholar
Fanconi anemia: a disorder defective in the DNA damage response
H. Kitao, M. Takata
2011International journal of hematology89 citations
Semantic Scholar
Epithelial Paradox: Clinical Significance of Coexpression of E‐cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer
N. Yamashita, E. Tokunaga, Makoto Iimori, Yuka Inoue +5 more
2018Clinical Breast Cancer88 citations
Semantic Scholar
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.
Yu-Liang Wu, Joshua A. Sommers, A. Suhasini, T. Leonard +5 more
2010Blood73 citations Open access
Semantic Scholar
Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair
Koichi Sato, M. Ishiai, Kazue Toda, Satoshi Furukoshi +10 more
2012EMBO Journal71 citations Open access
Semantic Scholar
Chromosomal Instability Associated with Global DNA Hypomethylation is Associated with the Initiation and Progression of Esophageal Squamous Cell Carcinoma
H. Kawano, H. Saeki, H. Kitao, Y. Tsuda +8 more
2014Annals of Surgical Oncology70 citations Open access
Semantic Scholar
Discrimination of p53 immunohistochemistry-positive tumors by its staining pattern in gastric cancer
K. Ando, E. Oki, H. Saeki, Zhao Yan +8 more
2014Cancer Medicine68 citations Open access
Semantic Scholar
Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer
E. Tokunaga, Y. Nakashima, N. Yamashita, Yuichi Hisamatsu +6 more
2012Breast Cancer66 citations
Semantic Scholar
Oxidative DNA damage in human esophageal cancer: clinicopathological analysis of 8-hydroxydeoxyguanosine and its repair enzyme.
Nobuhide Kubo, M. Morita, Y. Nakashima, H. Kitao +6 more
2014Diseases of the esophagus64 citations Open access
Semantic Scholar
High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer
K. Ando, Y. Kakeji, H. Kitao, Makoto Iimori +8 more
2010Cancer Science63 citations Open access
Semantic Scholar
Expression of PD-L1 and HLA Class I in Esophageal Squamous Cell Carcinoma: Prognostic Factors for Patient Outcome
Shuhei Ito, S. Okano, M. Morita, H. Saeki +10 more
2016Annals of Surgical Oncology62 citations
Semantic Scholar
Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks
Kazuaki Matsuoka, Makoto Iimori, Shinichiro Niimi, H. Tsukihara +9 more
2015Molecular Cancer Therapeutics60 citations Open access
Semantic Scholar
Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer.
N. Yamashita, E. Tokunaga, H. Kitao, M. Hitchins +10 more
2015Clinical Breast Cancer52 citations
Semantic Scholar
Mortalin is a prognostic factor of gastric cancer with normal p53 function
K. Ando, E. Oki, Yan Zhao, Ayae Ikawa-Yoshida +7 more
2014Gastric Cancer52 citations Open access
Semantic Scholar
Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer
R. Nakanishi, Jun Harada, M. Tuul, Yan Zhao +7 more
2013International Journal of Clinical Oncology48 citations
Semantic Scholar
Activation of downstream epidermal growth factor receptor (EGFR) signaling provides gefitinib‐resistance in cells carrying EGFR mutation
A. Uchida, Seiki Hirano, H. Kitao, Atsuko Ogino +7 more
2007Cancer Science48 citations Open access
Semantic Scholar
Functional Interplay between BRCA2/FancD1 and FancC in DNA Repair*
H. Kitao, Kazuhiko Yamamoto, Nobuko Matsushita, Mioko Ohzeki +2 more
2006Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Molecular mechanisms regulating the hormone sensitivity of breast cancer
E. Tokunaga, Yuichi Hisamatsu, Kimihiro Tanaka, N. Yamashita +4 more
2014Cancer Science43 citations Open access
Semantic Scholar
Copy-Neutral Loss of Heterozygosity at the p53 Locus in Carcinogenesis of Esophageal Squamous Cell Carcinomas Associated with p53 Mutations
H. Saeki, H. Kitao, Keiji Yoshinaga, Tomonori Nakanoko +4 more
2011Clinical Cancer Research43 citations
Semantic Scholar
High expression of the Notch ligand Jagged‐1 is associated with poor prognosis after surgery for colorectal cancer
M. Sugiyama, E. Oki, Y. Nakaji, S. Tsutsumi +13 more
2016Cancer Science42 citations Open access
Semantic Scholar
Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability
Makoto Iimori, Sugiko Watanabe, Shinichi Kiyonari, Kazuaki Matsuoka +5 more
2016Nature Communications41 citations Open access
Semantic Scholar
The Q Motif of Fanconi Anemia Group J Protein (FANCJ) DNA Helicase Regulates Its Dimerization, DNA Binding, and DNA Repair Function*
Yu-Liang Wu, Joshua A. Sommers, Jason A. Loiland, H. Kitao +3 more
2012Journal of Biological Chemistry40 citations Open access
Semantic Scholar
A requirement of FancL and FancD2 monoubiquitination in DNA repair
S. Seki, Mioko Ohzeki, A. Uchida, Seiki Hirano +8 more
2007Genes to Cells40 citations Open access
Semantic Scholar
Impact of Expression of Vimentin and Axl in Breast Cancer.
Kimihiro Tanaka, E. Tokunaga, Yuka Inoue, N. Yamashita +6 more
2016Clinical Breast Cancer37 citations Open access
Semantic Scholar
Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent–induced mitotic arrest
Y. Tsuda, Makoto Iimori, Y. Nakashima, R. Nakanishi +6 more
2017Scientific Reports36 citations Open access
Semantic Scholar
Prognostic impact of MutT homolog‐1 expression on esophageal squamous cell carcinoma
Shingo Akiyama, H. Saeki, Y. Nakashima, Makoto Iimori +6 more
2016Cancer Medicine35 citations Open access
Semantic Scholar
Podoplanin is expressed at the invasive front of esophageal squamous cell carcinomas and is involved in collective cell invasion
Y. Nakashima, Keiji Yoshinaga, H. Kitao, K. Ando +8 more
2013Cancer Science35 citations Open access
Semantic Scholar
Contribution of Aurora-A and -B expression to DNA aneuploidy in gastric cancers
K. Honma, R. Nakanishi, Tomonori Nakanoko, K. Ando +6 more
2014Surgery today (Print)34 citations
Semantic Scholar
Gastric Cancer Patients with High PLK1 Expression and DNA Aneuploidy Correlate with Poor Prognosis
Hajime Otsu, Makoto Iimori, K. Ando, H. Saeki +7 more
2016Oncology30 citations Open access
Semantic Scholar
The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis
Shinichi Kiyonari, Makoto Iimori, Kazuaki Matsuoka, Sugiko Watanabe +10 more
2015Molecular Cancer Therapeutics27 citations
Semantic Scholar
ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity.
Yoshihiko Fujinaka, Kazuaki Matsuoka, Makoto Iimori, M. Tuul +10 more
2012DNA Repair27 citations
Semantic Scholar
Rad9, Rad17, TopBP1 and Claspin Play Essential Roles in Heat-Induced Activation of ATR Kinase and Heat Tolerance
M. Tuul, H. Kitao, Makoto Iimori, Kazuaki Matsuoka +5 more
2013PLoS ONE26 citations Open access
Semantic Scholar
Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion.
H. Kitao, M. Kimura, Kazuhiko Yamamoto, Hidetaka Seo +4 more
2008International Immunology25 citations
Semantic Scholar
A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair
S. Bharti, Joshua A. Sommers, Sanket Awate, M. Bellani +14 more
2018Nucleic Acids Research23 citations Open access
Semantic Scholar
The antibodies against 5-bromo-2′-deoxyuridine specifically recognize trifluridine incorporated into DNA
H. Kitao, Y. Morodomi, Shinichiro Niimi, M. Kiniwa +8 more
2016Scientific Reports23 citations Open access
Semantic Scholar
PARP and CSB modulate the processing of transcription-mediated DNA strand breaks.
Akiko Sakai, Ryo Sakasai, Y. Kakeji, H. Kitao +1 more
2012Genes & Genetic Systems21 citations Open access
Semantic Scholar
Activation of the FA pathway mediated by phosphorylation and ubiquitination.
M. Ishiai, Koichi Sato, Junya Tomida, H. Kitao +2 more
2017Mutation research20 citations
Semantic Scholar
FANCJ Expression Predicts the Response to 5-Fluorouracil-Based Chemotherapy in MLH1-Proficient Colorectal Cancer
R. Nakanishi, H. Kitao, Yoshihiko Fujinaka, N. Yamashita +6 more
2012Annals of Surgical Oncology20 citations
Semantic Scholar
MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites
Sugiko Watanabe, Makoto Iimori, David Virya Chan, E. Hara +2 more
2018Scientific Reports19 citations Open access
Semantic Scholar
Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women
E. Tokunaga, N. Yamashita, Kimihiro Tanaka, Yuka Inoue +5 more
2016PLoS ONE19 citations Open access
Semantic Scholar
FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells
H. Kitao, I. Nanda, Ryuichi P. Sugino, A. Kinomura +6 more
2011Genes to Cells19 citations Open access
Semantic Scholar
Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.
Yan Zhao, K. Ando, E. Oki, Ayae Ikawa-Yoshida +6 more
2014Anticancer Research18 citations
Semantic Scholar
High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers
E. Tokunaga, Satoko Okada, N. Yamashita, S. Akiyoshi +4 more
2012Breast Cancer17 citations
Semantic Scholar
The Fanconi anemia pathway: insights from somatic cell genetics using DT40 cell line.
M. Takata, M. Ishiai, H. Kitao
2009Mutation research17 citations
Semantic Scholar
DNA Replication Stress Induced by Trifluridine Determines Tumor Cell Fate According to p53 Status
Y. Kataoka, Makoto Iimori, R. Fujisawa, Tomomi Morikawa-Ichinose +8 more
2019Molecular Cancer Research16 citations Open access
Semantic Scholar
Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level
Y. Kataoka, Makoto Iimori, Shinichiro Niimi, H. Tsukihara +5 more
2019Scientific Reports16 citations Open access
Semantic Scholar
Thymidine Kinase 1 Loss Confers Trifluridine Resistance without Affecting 5-Fluorouracil Metabolism and Cytotoxicity
Keitaro Edahiro, Makoto Iimori, T. Kobunai, Tomomi Morikawa-Ichinose +8 more
2018Molecular Cancer Research16 citations Open access
Semantic Scholar

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