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D. Jenne · SciRah

Researcher profile · Semantic Scholar

D. Jenne

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D. Jenne — researcher profile on SciRah

h-index: 54
Works: 157
Citations: 15K

Most-cited papers

Lifeact: a versatile marker to visualize F-actin
J. Riedl, Á. Crevenna, K. Kessenbrock, J. Yu +8 more
2008Nature Methods2,280 citations Open access
Semantic Scholar
Netting neutrophils in autoimmune small-vessel vasculitis
K. Kessenbrock, M. Krumbholz, U. Schönermarck, W. Back +5 more
2009Nature Medicine1,658 citations Open access
Semantic Scholar
Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases
B. Korkmaz, M. Horwitz, D. Jenne, F. Gauthier
2010Pharmacological Reviews855 citations Open access
Semantic Scholar
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.
K. Kessenbrock, L. Fröhlich, M. Sixt, T. Lämmermann +7 more
2008Journal of Clinical Investigation405 citations Open access
Semantic Scholar
MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies
N. Molnarfi, Ulf Schulze-Topphoff, Martin S. Weber, J. Patarroyo +12 more
2013Journal of Experimental Medicine399 citations Open access
Semantic Scholar
Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis
A. Pröbstel, K. Dornmair, R. Bittner, P. Sperl +26 more
2011Neurology306 citations
Semantic Scholar
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis
M. Leppkes, C. Maueröder, S. Hirth, Stefanie Nowecki +19 more
2016Nature Communications214 citations Open access
Semantic Scholar
The NLRP3/ASC/Caspase‐1 axis regulates IL‐1β processing in neutrophils
A. Mankan, T. Dau, D. Jenne, V. Hornung
2012European Journal of Immunology197 citations
Semantic Scholar
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein
M. Spadaro, S. Winklmeier, E. Beltrán, C. Macrini +19 more
2018Annals of Neurology180 citations
Semantic Scholar
Global Substrate Profiling of Proteases in Human Neutrophil Extracellular Traps Reveals Consensus Motif Predominantly Contributed by Elastase
A. O'Donoghue, Ye Jin, G. Knudsen, N. Perera +4 more
2013PLoS ONE138 citations Open access
Semantic Scholar
Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases
M. C. Mayer, C. Breithaupt, M. Reindl, K. Schanda +13 more
2013Journal of Immunology138 citations Open access
Semantic Scholar
Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.
F. Loison, Hai-Yan Zhu, Kutay Karatepe, A. Kasorn +9 more
2014Journal of Clinical Investigation130 citations Open access
Semantic Scholar
Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis.
Jean-Paul Motta, L. Magne, D. Descamps, C. Rolland +16 more
2010Gastroenterology120 citations
Semantic Scholar
Therapeutic targeting of cathepsin C: from pathophysiology to treatment
B. Korkmaz, G. Caughey, I. Chapple, F. Gauthier +16 more
2018Pharmacology and Therapeutics116 citations Open access
Semantic Scholar
NSP4, an elastase-related protease in human neutrophils with arginine specificity
N. Perera, O. Schilling, Heike Kittel, Walter Back +2 more
2012Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer
B. Schoeps, Celina Eckfeld, O. Prokopchuk, Jan P. Böttcher +8 more
2021Cancer Research115 citations Open access
Semantic Scholar
Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program.
E. Fellows, S. Gil-Parrado, D. Jenne, F. Kurschus
2007Blood113 citations
Semantic Scholar
Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.
N. Guyot, Julien Wartelle, L. Malleret, A. Todorov +4 more
2014American Journal of Pathology112 citations Open access
Semantic Scholar
Tailor-made inflammation: how neutrophil serine proteases modulate the inflammatory response
K. Kessenbrock, T. Dau, D. Jenne
2010Journal of molecular medicine103 citations Open access
Semantic Scholar
NSP4 Is Stored in Azurophil Granules and Released by Activated Neutrophils as Active Endoprotease with Restricted Specificity
N. Perera, K. Wiesmüller, M. T. Larsen, B. Schacher +3 more
2013Journal of Immunology83 citations Open access
Semantic Scholar
Direct detection of antibody concentration and affinity in human serum using microscale thermophoresis.
Svenja Lippok, S. Seidel, S. Duhr, K. Uhland +3 more
2012Analytical Chemistry81 citations
Semantic Scholar
Delivery and therapeutic potential of human granzyme B
Florian C. Kurschus, D. Jenne
2010Immunological Reviews79 citations
Semantic Scholar
A Hydrophobic Patch on Proteinase 3, the Target of Autoantibodies in Wegener Granulomatosis, Mediates Membrane Binding via NB1 Receptors*
B. Korkmaz, A. Kuhl, B. Bayat, S. Santoso +1 more
2008Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Intravenous immunoglobulins contain naturally occurring antibodies that mimic antineutrophil cytoplasmic antibodies and activate neutrophils in a TNFalpha-dependent and Fc-receptor-independent way.
S. Jarius, P. Eichhorn, M. Albert, S. Wagenpfeil +5 more
2007Blood67 citations Open access
Semantic Scholar
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases*
Y. Hamon, Monika Lęgowska, V. Hervé, S. Dallet‐Choisy +12 more
2016Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Lung Protection by Cathepsin C Inhibition: A New Hope for COVID-19 and ARDS?
B. Korkmaz, A. Lesner, S. Marchand-Adam, Celia Moss +1 more
2020Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity
V. Romero, E. Fellows, D. Jenne, Felipe Andrade
2009Cell Death and Differentiation61 citations
Semantic Scholar
Autosomal dominant myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7 is caused by a DES mutation
C. Hedberg, A. Melberg, A. Kuhl, D. Jenne +1 more
2012European Journal of Human Genetics56 citations Open access
Semantic Scholar
Common coding variant in SERPINA1 increases the risk for large artery stroke
R. Malik, T. Dau, M. Gonik, Anirudh Sivakumar +28 more
2017Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases
C. Guarino, Y. Hamon, Cécile Croix, A. Lamort +15 more
2017Biochemical Pharmacology54 citations
Semantic Scholar
Features of MOG required for recognition by patients with MOG antibody-associated disorders.
C. Macrini, R. Gerhards, S. Winklmeier, L. Bergmann +10 more
2021Brain : a journal of neurology53 citations Open access
Semantic Scholar
Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis)
B. Korkmaz, A. Lesner, Stéphanie Letast, Yassir K. Mahdi +7 more
2013Seminars in Immunopathology53 citations Open access
Semantic Scholar
Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis
F. Kurschus, E. Fellows, Elisabeth Stegmann, D. Jenne
2008Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Neutrophils Require SHP1 To Regulate IL-1β Production and Prevent Inflammatory Skin Disease
B. Croker, Rowena S. Lewis, Jeffery J Babon, J. Mintern +6 more
2011Journal of Immunology50 citations Open access
Semantic Scholar
Childhood overgrowth in patients with common NF1 microdeletions
M. Spiegel, K. Oexle, D. Horn, E. Windt +9 more
2005European Journal of Human Genetics49 citations
Semantic Scholar
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing
N. Kessler, S. Viehmann, Calvin Krollmann, Karola Mai +23 more
2022bioRxiv47 citations Open access
Semantic Scholar
Cathepsin c inhibition as a potential treatment strategy in cancer.
B. Korkmaz, A. Lamort, R. Domain, C. Beauvillain +6 more
2021Biochemical Pharmacology39 citations Open access
Semantic Scholar
Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.
B. Korkmaz, A. Lesner, M. Wysocka, A. Giełdoń +6 more
2019Biochemical Pharmacology37 citations Open access
Semantic Scholar
Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia
Seda Seren, L. Derian, I. Keleş, A. Guillon +9 more
2021European Respiratory Journal36 citations Open access
Semantic Scholar
New Selective Peptidyl Di(chlorophenyl) Phosphonate Esters for Visualizing and Blocking Neutrophil Proteinase 3 in Human Diseases*
C. Guarino, Monika Lęgowska, C. Epinette, C. Kellenberger +12 more
2014Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Discrimination and Variable Impact of ANCA Binding to Different Surface Epitopes on Proteinase 3, the Wegener’s Autoantigen
Francisco Silva, A. Hummel, D. Jenne, U. Specks
2010Journal of Autoimmunity35 citations Open access
Semantic Scholar
Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
B. Korkmaz, A. Lesner, C. Guarino, M. Wysocka +5 more
2016Pharmacological Reviews34 citations Open access
Semantic Scholar
Pathogenicity of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody in Granulomatosis With Polyangiitis: Implications as Biomarker and Future Therapies
J. Granel, B. Korkmaz, D. Nouar, S. Weiss +3 more
2021Frontiers in Immunology31 citations Open access
Semantic Scholar
Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome
C. Morrone, N. Smirnova, A. Jeridi, N. Kneidinger +6 more
2020European Respiratory Journal30 citations Open access
Semantic Scholar
Preservation with α1-antitrypsin improves primary graft function of murine lung transplants
Jessica Götzfried, N. Smirnova, C. Morrone, B. Korkmaz +3 more
2018The Journal of Heart and Lung Transplantation30 citations Open access
Semantic Scholar
Mapping of Conformational Epitopes on Human Proteinase 3, the Autoantigen of Wegener’s Granulomatosis
A. Kuhl, B. Korkmaz, B. Utecht, A. Kniepert +3 more
2010Journal of Immunology27 citations Open access
Semantic Scholar
Analysis of urinary cathepsin C for diagnosing Papillon–Lefèvre syndrome
Y. Hamon, Monika Lęgowska, P. Fergelot, S. Dallet‐Choisy +32 more
2016The FEBS Journal22 citations Open access
Semantic Scholar
A Monoclonal Antibody (MCPR3-7) Interfering with the Activity of Proteinase 3 by an Allosteric Mechanism*
Lisa C Hinkofer, S. Seidel, B. Korkmaz, Francisco Silva +4 more
2013Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: corroboration and narrowing of the critical region on 10q22.3
A. Kuhl, A. Melberg, E. Meinl, G. Nürnberg +3 more
2008European Journal of Human Genetics22 citations
Semantic Scholar
University of Birmingham Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis
Seda Seren, Maha Abouzaid, Claudia Eulenberg-Gustavus, J. Hirschfeld +30 more
201820 citations
Semantic Scholar

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S. Dallet‐Choisy

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