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Alan Cheng · SciRah

Researcher profile · Semantic Scholar

Alan Cheng

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Alan Cheng — researcher profile on SciRah

h-index: 27
Works: 34
Citations: 12K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy
D. Klionsky, F. C. Abdalla, H. Abeliovich, Robert T. Abraham +496 more
20124,979 citations Open access
Semantic Scholar
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene.
M. Elchebly, P. Payette, Eva Michaliszyn, W. Cromlish +10 more
1999Science2,237 citations
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.
Alan Cheng, N. Uetani, P. Simoncic, Vikas P. Chaubey +4 more
2002Developmental Cell553 citations Open access
Semantic Scholar
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
K. Tsukiyama-Kohara, F. Poulin, M. Kohara, C. Demaria +9 more
2001Nature Medicine414 citations
Semantic Scholar
Changes in integrin expression during adipocyte differentiation.
Jun Liu, Stephanie M. DeYoung, Ming Zhang, Mei Zhang +2 more
2005Cell Metabolism192 citations Open access
Semantic Scholar
Coordinated action of protein tyrosine phosphatases in insulin signal transduction.
Alan Cheng, Nadia Dubé, F. Gu, M. Tremblay
2002European Journal of Biochemistry183 citations
Semantic Scholar
The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals.
Min Chen, Alan Cheng, Yi-Qing Chen, Anka Hymel +6 more
1997Proceedings of the National Academy of Sciences of the United States of America162 citations Open access
Semantic Scholar
Protein Tyrosine Phosphatase 1B Attenuates Growth Hormone-Mediated JAK2-STAT Signaling
F. Gu, Nadia Dubé, J. W. Kim, Alan Cheng +3 more
2003Molecular and Cellular Biology147 citations Open access
Semantic Scholar
The role of protein tyrosine phosphatase 1B in Ras signaling
Nadia Dubé, Alan Cheng, M. Tremblay
2004Proceedings of the National Academy of Sciences of the United States of America142 citations Open access
Semantic Scholar
Complex Effects of Naturally Occurring Mutations in the JAK3 Pseudokinase Domain: Evidence for Interactions between the Kinase and Pseudokinase Domains
Min Chen, Alan Cheng, F. Candotti, Yong-Jie Zhou +4 more
2000Molecular and Cellular Biology137 citations Open access
Semantic Scholar
Regulation of Insulin-Like Growth Factor Type I (IGF-I) Receptor Kinase Activity by Protein Tyrosine Phosphatase 1B (PTP-1B) and Enhanced IGF-I-Mediated Suppression of Apoptosis and Motility in PTP-1B-Deficient Fibroblasts
D. A. Buckley, Alan Cheng, P. Kiely, M. Tremblay +1 more
2002Molecular and Cellular Biology124 citations Open access
Semantic Scholar
A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action
Xiao-Wei Chen, Dara E. Leto, T. Xiong, Geng-Geng Yu +3 more
2011Molecular Biology of the Cell111 citations Open access
Semantic Scholar
Attenuation of Adhesion-dependent Signaling and Cell Spreading in Transformed Fibroblasts Lacking Protein Tyrosine Phosphatase-1B
Alan Cheng, Gurjeet S. Bal, B. Kennedy, M. Tremblay
2001Journal of Biological Chemistry103 citations Open access
Semantic Scholar
Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development.
Nadia Dubé, A. Bourdeau, Krista M. Heinonen, Alan Cheng +2 more
2005Cancer Research99 citations Open access
Semantic Scholar
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.
Alan Cheng, Mei Zhang, Matthew S. Gentry, C. Worby +2 more
2007Genes & Development98 citations Open access
Semantic Scholar
Biochemical and Clinical Aspects of Glycogen Storage Diseases
Sara S. Ellingwood, Alan Cheng
2018Journal of Endocrinology83 citations Open access
Semantic Scholar
Metabolic Crosstalk: Molecular Links Between Glycogen and Lipid Metabolism in Obesity
Binbin Lu, D. Bridges, Yemen Yang, Kaleigh Fisher +9 more
2014Diabetes83 citations Open access
Semantic Scholar
Protein-tyrosine Phosphatase 1B Deficiency Protects against Fas-induced Hepatic Failure*
V. Sangwan, G. Paliouras, Alan Cheng, Nadia Dubé +2 more
2006Journal of Biological Chemistry66 citations Open access
Semantic Scholar
CAP interacts with cytoskeletal proteins and regulates adhesion‐mediated ERK activation and motility
Mei Zhang, Jun Liu, Alan Cheng, Stephanie M. DeYoung +3 more
2006EMBO Journal62 citations Open access
Semantic Scholar
Modulation of insulin signaling by protein tyrosine phosphatases
M. Elchebly, Alan Cheng, M. Tremblay
2000Journal of molecular medicine61 citations
Semantic Scholar
Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5.
Irfan J. Lodhi, D. Bridges, Shian-Huey Chiang, Yanling Zhang +4 more
2008Molecular Biology of the Cell56 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Identification of CAP as a costameric protein that interacts with filamin C.
Mei Zhang, Jun Liu, Alan Cheng, Stephanie M. DeYoung +1 more
2007Molecular Biology of the Cell42 citations Open access
Semantic Scholar
Distinct mutations in the glycogen debranching enzyme found in glycogen storage disease type III lead to impairment in diverse cellular functions.
Alan Cheng, Mei Zhang, M. Okubo, K. Omichi +1 more
2009Human Molecular Genetics29 citations Open access
Semantic Scholar
Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma.
Mélanie J. Chagnon, M. Elchebly, N. Uetani, L. Dombrowski +4 more
2006Canadian Journal of Physiology and Pharmacology29 citations
Semantic Scholar
The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein–protein interactions
Yuanqi Zhu, Mei Zhang, A. Kelly, Alan Cheng
2014Bioscience Reports28 citations Open access
Semantic Scholar
BMP-9 dependent pathways required for the chondrogenic differentiation of pluripotent stem cells.
Alan Cheng, A. Gustafson, Christine E. Schaner Tooley, Mei Zhang
2016Differentiation; research in biological diversity18 citations
Semantic Scholar
More TORC for the gluconeogenic engine.
Alan Cheng, A. Saltiel
2006Bioessays17 citations Open access
Semantic Scholar
Regulation of the mouse protein targeting to glycogen (PTG) promoter by the FoxA2 forkhead protein and by 3',5'-cyclic adenosine 5'-monophosphate in H4IIE hepatoma cells.
Alan Cheng, Mei Zhang, S. Crosson, Zhao-Qin Bao +1 more
2006Endocrinology14 citations
Semantic Scholar
Loss of protein targeting to glycogen sensitizes human hepatocellular carcinoma cells towards glucose deprivation mediated oxidative stress and cell death
Rongqiang Yang, Mei Zhang, A. Gustafson, E. Wang +3 more
2015Bioscience Reports7 citations Open access
Semantic Scholar
Von Gierke’s Disease Adopts an Orphan (and Its Partner)
Alan Cheng, A. Saltiel
2009Science Signaling3 citations
Semantic Scholar
Protein Tyrosine Phosphatases as Therapeutic Targets
Alan Cheng, N. Uetani, C. Lampron, M. Tremblay
20053 citations
Semantic Scholar
A novel transgenic mouse model of lysosomal storage disorder.
S. Ortiz-Miranda, Rui Ji, Agata Jurczyk, Ken-Edwin Aryee +9 more
2016American Journal of Physiology - Gastrointestinal and Liver Physiology2 citations Open access
Semantic Scholar

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