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Mark S. Lechner · SciRah

Researcher profile · Semantic Scholar

Mark S. Lechner

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Mark S. Lechner — researcher profile on SciRah

h-index: 17
Works: 25
Citations: 2,659

Most-cited papers

Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation.
K. Ayyanathan, Mark S. Lechner, Peter Bell, G. Maul +5 more
2003Genes & Development375 citations Open access
Semantic Scholar
Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53‐mediated repression of transcription.
Mark S. Lechner, D. Mack, A. B. Finicle, T. Crook +2 more
1992EMBO Journal276 citations Open access
Semantic Scholar
Multiple Organ System Defects and Transcriptional Dysregulation in the Nipbl +/− Mouse, a Model of Cornelia de Lange Syndrome
S. Kawauchi, Anne L. Calof, Rosaysela Santos, Martha E. Lopez-Burks +11 more
2009PLoS Genetics264 citations Open access
Semantic Scholar
Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis.
Q. Vega, C. Worby, Mark S. Lechner, J. Dixon +1 more
1996Proceedings of the National Academy of Sciences of the United States of America252 citations Open access
Semantic Scholar
Inhibition of p53 DNA binding by human papillomavirus E6 proteins
Mark S. Lechner, L. Laimins
1994Journal of Virology243 citations Open access
Semantic Scholar
Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential
Mark S. Lechner, Gillian E. Begg, D. Speicher, F. Rauscher
2000Molecular and Cellular Biology219 citations Open access
Semantic Scholar
The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.
Mark S. Lechner, D. Schultz, D. Negorev, G. Maul +1 more
2005Biochemical and Biophysical Research Communications - BBRC207 citations
Semantic Scholar
The molecular basis of embryonic kidney development.
Mark S. Lechner, G. Dressler
1997Mechanisms of Development191 citations Open access
Semantic Scholar
The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1).
Mohammed Dehbi, M. Ghahremani, Mark S. Lechner, G. Dressler +1 more
1996Oncogene128 citations
Semantic Scholar
Phosphorylation of Pax2 by the c-Jun N-terminal Kinase and Enhanced Pax2-dependent Transcription Activation*
Yi Cai, Mark S. Lechner, D. Nihalani, Marc J. Prindle +2 more
2002Journal of Biological Chemistry89 citations Open access
Semantic Scholar
PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin.
Mark S. Lechner, I. Levitan, G. Dressler
2000Nucleic Acids Research85 citations Open access
Semantic Scholar
Mapping of Pax-2 Transcription Activation Domains*
Mark S. Lechner, G. Dressler
1996Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule.
D. Phippard, A. Heydemann, Mark S. Lechner, Li-Hui Lu +3 more
1998Hearing Research63 citations Open access
Semantic Scholar
Corrigendum: Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription (The EMBO Journal(1992)11(3045-3052))
Mark S. Lechner, D. Mack, A. B. Finicle, T. Crook +2 more
199253 citations
Semantic Scholar
Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion.
A. Inoue, Judith W. Hyle, Mark S. Lechner, J. Lahti
2008Mutation research36 citations
Semantic Scholar
Mammalian ChlR1 has a role in heterochromatin organization
A. Inoue, Judith W. Hyle, Mark S. Lechner, J. Lahti
2011Experimental Cell Research29 citations Open access
Semantic Scholar
Computational systems biology of aging
A. Kriete, Mark S. Lechner, Drew Clearfield, D. Bohmann
2011Wiley Interdisciplinary Reviews: Systems Biology and Medicine28 citations
Semantic Scholar
Human epithelial cells immortalized by SV40 retain differentiation capabilities in an in vitro raft system and maintain viral DNA extrachromosomally.
Mark S. Lechner, L. Laimins
1991Virology15 citations
Semantic Scholar
Phylogenetics from paralogs
Marc Hellmuth, N. Wieseke, Mark S. Lechner, Hans-Peter Lenhof +2 more
201414 citations
Semantic Scholar
Cell cycle dependent role of HDAC1 for proliferation control through modulating ribosomal DNA transcription
J. Meraner, Mark S. Lechner, Florian Schwarze, R. Gander +2 more
2008Cell Biology International9 citations
Semantic Scholar
In Vitro Phosphorylation and Acetylation of the Murine Pocket Protein Rb2/p130
M. Saeed, Florian Schwarze, A. Loidl, J. Meraner +2 more
2012PLoS ONE8 citations Open access
Semantic Scholar
Insights Into Cornelia de Lange Syndrome From the Nipbl-Mutant Mouse
Anne L. Calof, S. Kawauchi, Rosaysela Santos, Martha E. Lopez-Burks +8 more
20103 citations
Semantic Scholar
KAP-1 Corepressor Interaction Is Essential − Silencing : Direct Chromoshadow Domain Heterochromatin Protein 1-Mediated Gene Molecular Determinants for Targeting
Mark S. Lechner, Gillian E. Begg, D. Speicher, F. Rauscher
20001 citations
Semantic Scholar
Title Multiple organ system defects and transcriptional dysregulation in the Nipbl + /-mouse , a model of Cornelia de Lange syndrome
S. Kawauchi, Anne L. Calof, Rosaysela Santos, Martha E. Lopez-Burks +13 more
20090 citations
Semantic Scholar
Characterization of the NIPBL protein associated with Cornelia de Lange Syndrome
D. Keter, Mark S. Lechner, M. Howett, A. Saunders +2 more
20080 citations
Semantic Scholar

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