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Srinivas Somarowthu · SciRah

Researcher profile · Semantic Scholar

Srinivas Somarowthu

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Srinivas Somarowthu — researcher profile on SciRah

h-index: 17
Works: 41
Citations: 1,263

Most-cited papers

HOTAIR forms an intricate and modular secondary structure
Srinivas Somarowthu, M. Legiewicz, Isabel Chillón, M. Marcia +2 more
2015Molecules and Cells332 citations Open access
Semantic Scholar
Author Correction: Visualizing group II intron dynamics between the first and second steps of splicing
Jacopo Manigrasso, Isabel Chillón, V. Genna, Pietro Vidossich +4 more
2022Nature Communications213 citations Open access
Semantic Scholar
Visualizing the secondary and tertiary architectural domains of lncRNA RepA
Fei Liu, Srinivas Somarowthu, A. Pyle
2017Nature Chemical Biology115 citations Open access
Semantic Scholar
Native Purification and Analysis of Long RNAs
Isabel Chillón, M. Marcia, M. Legiewicz, Fei Liu +2 more
2015Methods in Enzymology67 citations Open access
Semantic Scholar
Visualizing group II intron dynamics between the first and second steps of splicing
Jacopo Manigrasso, Isabel Chillón, V. Genna, Pietro Vidossich +4 more
2020Nature Communications53 citations Open access
Semantic Scholar
High-performance prediction of functional residues in proteins with machine learning and computed input features.
Srinivas Somarowthu, Huyuan Yang, D. G. Hildebrand, M. Ondrechen
2011Biopolymers49 citations
Semantic Scholar
Phylogenetic analysis with improved parameters reveals conservation in lncRNA structures
R. Tavares, A. Pyle, Srinivas Somarowthu
2019Journal of Molecular Biology45 citations Open access
Semantic Scholar
Now on display: a gallery of group II intron structures at different stages of catalysis
M. Marcia, Srinivas Somarowthu, A. Pyle
2013Mobile DNA44 citations Open access
Semantic Scholar
A tale of two isomerases: compact versus extended active sites in ketosteroid isomerase and phosphoglucose isomerase.
Srinivas Somarowthu, Heather R. Brodkin, J. D'Aquino, D. Ringe +2 more
2011Biochemistry37 citations
Semantic Scholar
Bioinformatics Applications Note Structural Bioinformatics Pool Server: Machine Learning Application for Functional Site Prediction in Proteins
Srinivas Somarowthu, M. Ondrechen
37 citations
Semantic Scholar
Xist attenuates acute inflammatory response by female cells
Botros B. Shenoda, Sujay Ramanathan, Richa Gupta, Yu-Zhen Tian +6 more
2020Cellular and Molecular Life Sciences36 citations Open access
Semantic Scholar
Replication protein A binds RNA and promotes R-loop formation
O. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, A. Baranovskiy +3 more
2020Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Prediction of distal residue participation in enzyme catalysis
H. Brodkin, Nicholas A. DeLateur, Srinivas Somarowthu, Caitlyn L. Mills +4 more
2015Protein Science32 citations Open access
Semantic Scholar
Progress and current challenges in modeling large RNAs
Srinivas Somarowthu
2015Journal of Molecular Biology21 citations Open access
Semantic Scholar
Functional classification of protein 3D structures from predicted local interaction sites.
Ramya Parasuram, Joslynn S. Lee, Pengcheng Yin, Srinivas Somarowthu +1 more
2010Journal of Bioinformatics and Computational Biology21 citations
Semantic Scholar
Solving nucleic acid structures by molecular replacement: examples from group II intron studies
M. Marcia, Elisabeth Humphris-Narayanan, Kevin S. Keating, Srinivas Somarowthu +2 more
2013Acta Crystallographica Section D: Biological Crystallography20 citations Open access
Semantic Scholar
Protein function annotation with Structurally Aligned Local Sites of Activity (SALSAs)
Zhouxi Wang, Pengcheng Yin, Joslynn S. Lee, Ramya Parasuram +2 more
2013BMC Bioinformatics19 citations Open access
Semantic Scholar
The interplay of long noncoding RNAs and hepatitis B virus
Nima Sarfaraz, Srinivas Somarowthu, Michael Bouchard
2022Journal of Medical Virology17 citations
Semantic Scholar
Identifying Structural Domains and Conserved Regions in the Long Non-Coding RNA lncTCF7
Michael C. Owens, Sean C. Clark, Allison Yankey, Srinivas Somarowthu
2019International Journal of Molecular Sciences15 citations Open access
Semantic Scholar
Visualizing the ai5γ group IIB intron
Srinivas Somarowthu, M. Legiewicz, Kevin S. Keating, A. Pyle
2013Nucleic Acids Research13 citations Open access
Semantic Scholar
Covariation analysis with improved parameters reveals conservation in lncRNA structures
R. Tavares, A. Pyle, Srinivas Somarowthu
2018bioRxiv12 citations Open access
Semantic Scholar
Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity
G. Han, J. Ko, C. Farr, M. Deller +12 more
2011Proteins: Structure, Function, and Bioinformatics12 citations Open access
Semantic Scholar
Purification and Structural Characterization of the Long Noncoding RNAs.
Allison Yankey, Sean C. Clark, Michael C. Owens, Srinivas Somarowthu
2021Methods in molecular biology6 citations
Semantic Scholar
Decoding the lncRNA World: Comprehensive Approaches to lncRNA Structure and Interactome Studies
Mihyun Oh, B. Lee, Srinivas Somarowthu
2026Cells5 citations
Semantic Scholar
A novel partnership between lncTCF7 and SND1 regulates the expression of the TCF7 gene via recruitment of the SWI/SNF complex
Allison Yankey, Mihyun Oh, B. Lee, Tisha Kalpesh Desai +1 more
2024Scientific Reports4 citations Open access
Semantic Scholar
LncRNA SChLAP1 promotes cancer cell proliferation and invasion via its distinct structural domains and conserved regions
Mihyun Oh, R. N. Kadam, Z. Charania, Srinivas Somarowthu
2025bioRxiv3 citations
Semantic Scholar
LncRNA SChLAP1 Promotes Cancer Cell Proliferation and Invasion Via Its Distinct Structural Domains and Conserved Regions
Mihyun Oh, R. N. Kadam, Z. Charania, Srinivas Somarowthu
2025Journal of Molecular Biology2 citations Open access
Semantic Scholar
The Liver-Enriched Long Non-Coding RNA FAM99A Suppresses Tumorigenesis through Negative Regulation of Protein Synthesis
Nima Sarfaraz, R. Kaur, Sky Harper, Lilly Oni +2 more
2025bioRxiv1 citations Open access
Semantic Scholar
Deletion of the MALAT1 RNA 3’ end Promotes Transcript Decay and Inhibits Proliferation in Gastric and Breast Cancer Cells
Aramis Cortes-Arias, Valeria Valdes, Marcelo Muñoz-González, D. Leiva +11 more
2026bioRxiv0 citations Open access
Semantic Scholar
Transcriptional Profiling of Commonly Used Liver Cancer Cell Lines Reveals Disease-Specific Modeling Potential and Authentication Concerns
Nima Sarfaraz, Gail L. Rosen, T. Winkler, R. Patel +2 more
2025bioRxiv0 citations Open access
Semantic Scholar
Female-specific Long Non-coding RNA Xist-E3 Ligase Interactions Regulate Acute Inflammatory Pain In Females
Jason R. Wickman, Richa Gupta, Sujay Ramanathan, Botros B. Shenoda +5 more
2025Journal of Pain0 citations Open access
Semantic Scholar
Structural characterization of the Long Non‐Coding RNA SChLAP1
Mihyun Oh, Srinivas Somarowthu
2022The FASEB Journal0 citations
Semantic Scholar
Author Correction: Visualizing group II intron dynamics between the first and second steps of splicing
Jacopo Manigrasso, Isabel Chillón, V. Genna, Pietro Vidossich +4 more
2022Nature Communications0 citations Open access
Semantic Scholar
Visualizing group II intron dynamics between the first and second steps of splicing
Jacopo Manigrasso, Isabel Chillón, V. Genna, Pietro Vidossich +4 more
2020Nature Communications0 citations Open access
Semantic Scholar
Abstract IA25: Regulatory control of lincRNA function through formation of complex RNA structural motifs
Isabel Chillón, Srinivas Somarowthu, Fei Liu, A. Pyle
20160 citations
Semantic Scholar
Computational prediction and validation of putative ketosteroid isomerase (KSI) structural genomics proteins
Nicholas A. DeLateur, Srinivas Somarowthu, Colleen Shea, MarkVic Naniong +2 more
20130 citations
Semantic Scholar
Prediction and experimental verification of compact versus extended enzyme active sites: a tale of two isomerases.
Srinivas Somarowthu
20110 citations
Semantic Scholar
Exploring the effects of lncRNA FAM99B in hepatocellular carcinoma
T. Campbell, Srinivas Somarowthu
0 citations
Semantic Scholar
Structural and functional dissection of the oncogenic lncRNA SChLAP1
Mihyun Oh, Srinivas Somarowthu
0 citations
Semantic Scholar
Investigating the mechanism of lncRNA SChLAP1 in prostate cancer
Zoe Coutu, Srinivas Somarowthu
0 citations
Semantic Scholar
Optimization of the electroporation procedure for OG1RF Enterococcus faecalis to study VanRS_B activation using VanRS_B-GFP reporter construct
Temidayo Adegbenro, Srinivas Somarowthu
0 citations Open access
Semantic Scholar

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