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G. Han · SciRah

Researcher profile · Semantic Scholar

G. Han

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G. Han — researcher profile on SciRah

h-index: 58
Works: 248
Citations: 18K

Most-cited papers

Crystal structures of agonist-bound human cannabinoid receptor CB1
T. Hua, K. Vemuri, S. Nikas, R. Laprairie +16 more
2017Nature430 citations Open access
Semantic Scholar
Structure of a nanobody-stabilized active state of the kappa opioid receptor
T. Che, S. Majumdar, Saheem A. Zaidi, P. Ondachi +20 more
2018Cell331 citations Open access
Semantic Scholar
Crystal Structure of the Human Cannabinoid Receptor CB2
Xiao-Ting Li, T. Hua, K. Vemuri, Jo-Hao Ho +20 more
2019Cell329 citations Open access
Semantic Scholar
Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists
Yi Zheng, L. Qin, N. V. Ortiz Zacarías, H. D. de Vries +15 more
2016Nature274 citations Open access
Semantic Scholar
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology
Yao Peng, J. McCorvy, K. Harpsøe, K. Lansu +22 more
2018Cell235 citations Open access
Semantic Scholar
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
Gaojie Song, De-Hua Yang, Yu-Xia Wang, C. de Graaf +18 more
2017Nature214 citations
Semantic Scholar
Structural Basis for Selectivity and Diversity in Angiotensin II Receptors
Haitao Zhang, G. Han, A. Batyuk, A. Ishchenko +22 more
2017Nature203 citations Open access
Semantic Scholar
Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor
M. Eddy, Ming-Yue Lee, Zhang-Guo Gao, K. White +9 more
2017Cell200 citations Open access
Semantic Scholar
Structural insights into lipid and ligand regulation of serotonin receptors
B. Stauch, L. Johansson, J. McCorvy, N. Patel +23 more
2019Nature196 citations Open access
Semantic Scholar
Structure of the full-length glucagon class B G protein-coupled receptor
Hao-Nan Zhang, Anna Qiao, De-Hua Yang, Lin-Lin Yang +29 more
2017Nature192 citations Open access
Semantic Scholar
Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling
K. White, M. Eddy, Zhang-Guo Gao, G. Han +6 more
2018Structure177 citations Open access
Semantic Scholar
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV
Yi Zheng, G. Han, R. Abagyan, Beili Wu +4 more
2017Immunity148 citations Open access
Semantic Scholar
Structural basis of ligand recognition and self-activation of orphan GPR52
Xi Lin, Ming-Yue Li, Ni Wang, Yi-Ran Wu +12 more
2020Nature143 citations
Semantic Scholar
Structural basis of the activation of a metabotropic GABA receptor
H. Shaye, A. Ishchenko, J. Lam, G. Han +6 more
2020Nature124 citations Open access
Semantic Scholar
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
T. Claff, Jing Yu, Véronique Blais, N. Patel +15 more
2019Science Advances120 citations Open access
Semantic Scholar
XFEL structures of the human MT2 melatonin receptor reveal basis of subtype selectivity
L. Johansson, B. Stauch, J. McCorvy, G. Han +20 more
2019Nature120 citations Open access
Semantic Scholar
Full-length human GLP-1 receptor structure without orthosteric ligands
Fan Wu, Lin-Lin Yang, K. Hang, M. Laursen +11 more
2020Nature Communications115 citations Open access
Semantic Scholar
Structural basis of GABA reuptake inhibition
Zenia Motiwala, N. G. Aduri, H. Shaye, G. Han +4 more
2022Nature109 citations Open access
Semantic Scholar
Crystal structure of the Frizzled 4 receptor in a ligand-free state
Shifan Yang, Yi-Ran Wu, Ting-Hai Xu, P. de Waal +21 more
2018Nature107 citations
Semantic Scholar
Native phasing of x-ray free-electron laser data for a G protein–coupled receptor
A. Batyuk, L. Galli, A. Ishchenko, G. Han +23 more
2016Science Advances106 citations Open access
Semantic Scholar
Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding
Jing Yu, L. Gimenez, C. C. Hernandez, Yi-Ran Wu +15 more
2020Science105 citations Open access
Semantic Scholar
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand
Xianjun Zhang, Fei Zhao, Yi-Ran Wu, Jun Yang +17 more
2017Nature Communications101 citations Open access
Semantic Scholar
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs
A. Luginina, A. Gusach, E. Marin, A. Mishin +22 more
2019Science Advances99 citations Open access
Semantic Scholar
Structural basis for signal recognition and transduction by platelet-activating-factor receptor
C. Cao, Q. Tan, Chan-Juan Xu, Lingli He +18 more
2018Nature Structural & Molecular Biology67 citations
Semantic Scholar
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
A. Ishchenko, D. Wacker, M. Kapoor, Ai Zhang +10 more
2017Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Structural insight into apelin receptor-G protein stoichiometry
Yang Yue, Lier Liu, Lijie Wu, Yi-Ran Wu +15 more
2022Nature Structural & Molecular Biology61 citations
Semantic Scholar
Toward G protein-coupled receptor structure-based drug design using X-ray lasers
A. Ishchenko, B. Stauch, G. Han, A. Batyuk +14 more
2019IUCrJ58 citations Open access
Semantic Scholar
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor
M. Audet, K. White, B. Breton, B. Zarzycka +15 more
2018Nature Chemical Biology51 citations Open access
Semantic Scholar
Structural Basis of the Diversity of Adrenergic Receptors.
L. Qu, Qingtong Zhou, Yueming Xu, Yu Guo +8 more
2019Cell Reports44 citations Open access
Semantic Scholar
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
Lu Xu, Bo Chen, Hannes Schihada, Shane C. Wright +11 more
2021Cell Research38 citations Open access
Semantic Scholar
XFEL crystal structure of human melatonin receptor MT2 (H208A) in complex with 2-phenylmelatonin
L. Johansson, B. Stauch, J. McCorvy, G. Han +16 more
201938 citations
Semantic Scholar
Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma
R. Perryman, Alexander Renziehausen, H. Shaye, Androniki D. Kostagianni +20 more
2022Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
Structural insights into the molecular mechanisms of myasthenia gravis and their therapeutic implications
K. Noridomi, Go Watanabe, M. N. Hansen, G. Han +1 more
2017eLife29 citations Open access
Semantic Scholar
Structural insights into the human niacin receptor HCA2-Gi signalling complex
Yang Yang, H. Kang, R. Gao, Jingjing Wang +17 more
2023Nature Communications24 citations Open access
Semantic Scholar
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor
A. Shiriaeva, D. Park, Gyudong Kim, Yoonji Lee +13 more
2022Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α2C Adrenergic Receptor.
Xiaoyu Chen, Yueming Xu, L. Qu, Lijie Wu +21 more
2019Cell Reports23 citations Open access
Semantic Scholar
A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure
Jack C Li, Fariborz Nastertorabi, Weimin Xuan, G. Han +2 more
2019ACS Chemical Biology23 citations Open access
Semantic Scholar
Structural insights on ligand recognition at the human leukotriene B4 receptor 1
N. Michaelian, A. Sadybekov, É. Besserer-Offroy, G. Han +11 more
2021Nature Communications22 citations Open access
Semantic Scholar
Generation of an Orthogonal Protein-Protein Interface with a Noncanonical Amino Acid.
Minseob Koh, F. Nasertorabi, G. Han, R. Stevens +1 more
2017Journal of the American Chemical Society22 citations
Semantic Scholar
The activation mechanism and antibody binding mode for orphan GPR20
Xi Lin, Shan Jiang, Yi-Ran Wu, Xiaohu Wei +8 more
2023Cell Discovery20 citations Open access
Semantic Scholar
“An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli”
Claudio Zambaldo, Minseob Koh, F. Nasertorabi, G. Han +3 more
2020Bioorganic & Medicinal Chemistry17 citations Open access
Semantic Scholar
High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists.
Raphaël Bolteau, R. Duroux, Amélie Laversin, Brandon Vreulz +11 more
2022European journal of medicinal chemistry15 citations Open access
Semantic Scholar
Publisher Correction: Structural basis of ligand recognition at the human MT1 melatonin receptor
B. Stauch, L. Johansson, J. McCorvy, N. Patel +23 more
2019Nature15 citations Open access
Semantic Scholar
Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase
Ming-Yue Lee, J. Geiger, A. Ishchenko, G. Han +10 more
2020IUCrJ14 citations Open access
Semantic Scholar
Publisher Correction: Structural basis of GABA reuptake inhibition
Zenia Motiwala, N. G. Aduri, H. Shaye, G. Han +4 more
2022Nature3 citations Open access
Semantic Scholar
A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure.
Jack C Li, F. Nasertorabi, Weimin Xuan, G. Han +2 more
2020ACS Chemical Biology3 citations
Semantic Scholar
Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor
Tao Che, S. Majumdar, Saheem A. Zaidi, C. Kormos +20 more
20183 citations
Semantic Scholar
Advances in Structure Determination of G Protein-Coupled Receptors by SFX
B. Stauch, L. Johansson, A. Ishchenko, G. Han +2 more
20182 citations
Semantic Scholar
XFEL beta2 AR structure by ligand exchange from Alprenolol to Carazolol.
A. Ishchenko, B. Stauch, G. Han, A. Batyuk +14 more
20191 citations
Semantic Scholar
Crystal structure of the active delta opioid receptor in complex with the small molecule agonist DPI-287
T. Claff, Jing Yu, Véronique Blais, N. Patel +14 more
20191 citations
Semantic Scholar

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