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J. K. Oeser · SciRah

Researcher profile · Semantic Scholar

J. K. Oeser

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J. K. Oeser — researcher profile on SciRah

h-index: 23
Works: 55
Citations: 1,639

Most-cited papers

Deletion of the Mouse Slc30a8 Gene Encoding Zinc Transporter-8 Results in Impaired Insulin Secretion
Lynley D. Pound, S. Sarkar, R. Benninger, Yingda Wang +10 more
2009Biochemical Journal185 citations Open access
Semantic Scholar
The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements.
Beth T. Vander Kooi, H. Onuma, J. K. Oeser, C. A. Svitek +4 more
2005Molecular Endocrinology153 citations
Semantic Scholar
Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein.
C. C. Martin, J. K. Oeser, C. A. Svitek, S. Hunter +2 more
2002Journal of Molecular Endocrinology106 citations
Semantic Scholar
Cloning and Characterization of the Human and Rat Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein (IGRP) Genes*
C. C. Martin, L. J. Bischof, B. Bergman, L. A. Hornbuckle +11 more
2001Journal of Biological Chemistry82 citations Open access
Semantic Scholar
G6PC2: A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion
Lynley D. Pound, J. K. Oeser, Tracy P. O'Brien, Yingda Wang +7 more
2013Diabetes79 citations Open access
Semantic Scholar
The Three Insulin Response Sequences in the Glucose-6-phosphatase Catalytic Subunit Gene Promoter Are Functionally Distinct*
Beth T. Vander Kooi, R. Streeper, C. A. Svitek, J. K. Oeser +2 more
2003Journal of Biological Chemistry76 citations Open access
Semantic Scholar
Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin.
H. Onuma, Beth T. Vander Kooi, Jared N. Boustead, J. K. Oeser +1 more
2006Molecular Endocrinology75 citations Open access
Semantic Scholar
Hepatocyte nuclear factor-4 alpha mediates the stimulatory effect of peroxisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1 alpha) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells.
Jared N. Boustead, Beth T. Stadelmaier, A. Eeds, Peter O. Wiebe +3 more
2003Biochemical Journal68 citations Open access
Semantic Scholar
Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype
Yingda Wang, C. C. Martin, J. K. Oeser, S. Sarkar +3 more
2007Diabetologia65 citations Open access
Semantic Scholar
Gluconeogenesis: Re-evaluating the FOXO1–PGC-1α connection
Marcia M. Schilling, J. K. Oeser, Jared N. Boustead, B. P. Flemming +1 more
2006Nature47 citations
Semantic Scholar
Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subunit-related protein (IGRP) gene expression.
C. C. Martin, C. A. Svitek, J. K. Oeser, Eva K. Henderson +2 more
2003Biochemical Journal43 citations Open access
Semantic Scholar
The Pancreatic Islet Beta Cell-Enriched Transcription Factor Pdx-1 Regulates Slc30a8 Gene Transcription Through an Intronic Enhancer
Lynley D. Pound, Y. Hang, S. Sarkar, Yingda Wang +7 more
2011Biochemical Journal37 citations Open access
Semantic Scholar
Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion.
Kristen E. Syring, Kayla A Boortz, J. K. Oeser, A. Ustione +6 more
2016Endocrinology36 citations Open access
Semantic Scholar
Protein Kinase A Phosphorylates Hepatocyte Nuclear Factor-6 and Stimulates Glucose-6-phosphatase Catalytic Subunit Gene Transcription*
R. Streeper, L. A. Hornbuckle, C. A. Svitek, Joshua K. Goldman +2 more
2001Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Multiple Functional Polymorphisms in the G6PC2 Gene Contribute to the Association with Higher Fasting Plasma Glucose Levels
D. A. Baerenwald, A. Bonnefond, N. Bouatia-Naji, B. P. Flemming +14 more
2013Diabetologia34 citations Open access
Semantic Scholar
Genetic and Functional Assessment of the Role of the rs13431652-A and rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated With Elevated Fasting Glucose Levels
N. Bouatia-Naji, A. Bonnefond, D. A. Baerenwald, M. Marchand +19 more
2010Diabetes34 citations Open access
Semantic Scholar
Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein.
Jared N. Boustead, C. C. Martin, J. K. Oeser, C. A. Svitek +3 more
2004Journal of Molecular Endocrinology28 citations Open access
Semantic Scholar
Characterization of the mouse islet-specific glucose-6-phosphatase catalytic subunit-related protein gene promoter by in situ footprinting: correlation with fusion gene expression in the islet-derived betaTC-3 and hamster insulinoma tumor cell lines.
L. J. Bischof, C. C. Martin, C. A. Svitek, Beth T. Stadelmaier +5 more
2001Diabetes28 citations
Semantic Scholar
Deletion of the Gene Encoding the Ubiquitously Expressed Glucose-6-phosphatase Catalytic Subunit-related Protein (UGRP)/Glucose-6-phosphatase Catalytic Subunit-β Results in Lowered Plasma Cholesterol and Elevated Glucagon*
Yingda Wang, J. K. Oeser, Chun-Mei Yang, S. Sarkar +7 more
2006Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Pancreatic Islet Beta Cell-Specific Deletion of G6pc2 Reduces Fasting Blood Glucose
Karin J. Bosma, Mohsin Rahim, Kritika Singh, S. Goleva +12 more
2020Journal of Molecular Endocrinology26 citations Open access
Semantic Scholar
Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ.
L. A. Hornbuckle, Carrie A Everett, C. C. Martin, Stephanie S Gustavson +5 more
2004American Journal of Physiology. Endocrinology and Metabolism26 citations
Semantic Scholar
Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection.
Marcia M. Schilling, J. K. Oeser, Jared N. Boustead, B. P. Flemming +1 more
2006Nature25 citations
Semantic Scholar
Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo.
L. A. Hornbuckle, D. Edgerton, Julio E. Ayala, C. A. Svitek +5 more
2001American Journal of Physiology. Endocrinology and Metabolism23 citations
Semantic Scholar
Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1
D. P. Claxton, Emily M. Overway, J. K. Oeser, R. M. O'Brien +1 more
2021Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Foxa2 and MafA Regulate Islet-specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein (IGRP/G6PC2) Gene Expression
C. C. Martin, B. P. Flemming, Yingda Wang, J. K. Oeser +1 more
2008Journal of Molecular Endocrinology19 citations Open access
Semantic Scholar
Long-Range Enhancers Are Required to Maintain Expression of the Autoantigen Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein in Adult Mouse Islets In Vivo
Yingda Wang, B. P. Flemming, C. C. Martin, S. Allen +4 more
2008Diabetes19 citations Open access
Semantic Scholar
Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells
Mohsin Rahim, Arya Y. Nakhe, Deveena R. Banerjee, Emily M. Overway +8 more
2022Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Differential Regulation of Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein Gene Transcription by Pax-6 and Pdx-1*
C. C. Martin, J. K. Oeser, R. M. O'Brien
2004Journal of Biological Chemistry17 citations Open access
Semantic Scholar
G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.
Kayla A Boortz, Kristen E. Syring, Rebecca A. Lee, C. Dai +4 more
2016Endocrinology16 citations Open access
Semantic Scholar
G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to Stress.
Kayla A Boortz, Kristen E. Syring, C. Dai, Lynley D. Pound +6 more
2016Endocrinology16 citations Open access
Semantic Scholar
Characterization of the Human SLC30A8 Promoter and Intronic Enhancer
Lynley D. Pound, S. Sarkar, S. Cauchi, Yingda Wang +5 more
2011Journal of Molecular Endocrinology16 citations Open access
Semantic Scholar
G 6 PC 2 A Negative Regulator of Basal Glucose-Stimulated Insulin Secretion
Lynley D. Pound, J. K. Oeser, O. TracyP., Brien +8 more
201215 citations
Semantic Scholar
Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice
J. K. Oeser, V. Parekh, Yingda Wang, Naresh K. Jegadeesh +7 more
2011Diabetes14 citations Open access
Semantic Scholar
Potential Positive and Negative Consequences of ZnT8 Inhibition
Kristen E. Syring, Karin J. Bosma, S. Goleva, Kritika Singh +7 more
2020Journal of Endocrinology13 citations Open access
Semantic Scholar
The proximal islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen promoter is sufficient to initiate but not maintain transgene expression in mouse islets in vivo.
C. Frigeri, C. C. Martin, C. A. Svitek, J. K. Oeser +3 more
2004Diabetes13 citations Open access
Semantic Scholar
Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose
Emily M. Overway, Karin J. Bosma, D. P. Claxton, J. K. Oeser +5 more
2021Journal of Biological Chemistry12 citations Open access
Semantic Scholar
G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting
Karin J. Bosma, Mohsin Rahim, J. K. Oeser, O. McGuinness +2 more
2020Molecular Metabolism12 citations Open access
Semantic Scholar
Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.
Julio E. Ayala, Jared N. Boustead, Stacey C. Chapman, C. A. Svitek +3 more
2004Journal of Molecular Endocrinology12 citations Open access
Semantic Scholar
Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1α
Marcia M. Schilling, J. K. Oeser, Joshua K. Chandy, B. P. Flemming +2 more
2008Diabetologia11 citations Open access
Semantic Scholar
Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression
Kayla A Boortz, Kristen E. Syring, Lynley D. Pound, Yingda Wang +2 more
2016PLoS ONE10 citations Open access
Semantic Scholar
Accessory Elements, Flanking DNA Sequence, and Promoter Context Play Key Roles in Determining the Efficacy of Insulin and Phorbol Ester Signaling through the Malic Enzyme and Collagenase-1 AP-1 Motifs*
Julio E. Ayala, R. Streeper, C. A. Svitek, Joshua K. Goldman +2 more
2002Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Effects of G6pc2 Deletion on Body Weight and Cholesterol in Mice
Kayla A Boortz, Kristen E. Syring, Lynley D. Pound, Huan Mo +5 more
2017Journal of Molecular Endocrinology7 citations Open access
Semantic Scholar
Insulin and Epidermal Growth Factor Suppress Basal Glucose-6-Phosphatase Catalytic Subunit Gene Transcription Through Overlapping but Distinct Mechanisms
H. Onuma, J. K. Oeser, Bryce A. Nelson, Yingda Wang +4 more
2009Biochemical Journal7 citations Open access
Semantic Scholar
Evidence That Evolution of the Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 Drives Variations in Pancreatic Islet Zinc Content in Multiple Species
Karin J. Bosma, Kristen E. Syring, J. K. Oeser, J. Lee +3 more
2019Journal of Molecular Evolution5 citations Open access
Semantic Scholar
Identiﬁcation and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein
C. C. Martin, J. K. Oeser, C. A. Svitek, S. Hunter +2 more
5 citations
Semantic Scholar
The Diabetes Susceptibility Gene SLC30A8 that Encodes the Zinc Transporter ZnT8 is a Pseudogene in Guinea Pigs Potentially Contributing to Low Guinea Pig Islet Zinc Content
Kristen E. Syring, Karin J. Bosma, J. K. Oeser, M. Shiota +1 more
2018Journal of Molecular Evolution4 citations Open access
Semantic Scholar
Biochemical and Metabolic Characterization of a G6PC2 Inhibitor
Emily M. Hawes, Mohsin Rahim, Zeinab Haratipour, Abigail R. Orun +7 more
2024Biochimie3 citations Open access
Semantic Scholar
Hepatocyte nuclear factor-4 a mediates the stimulatory effect of peroxisome proliferator-activated receptor c co-activator-1 a (PGC-1 a ) on glucose-6-phosphatase catalytic subunit gene transcription in H4IIE cells
Jared N. Boustead, Beth T. Stadelmaier, A. Eeds, Peter O. Wiebe +3 more
3 citations
Semantic Scholar
Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model
Richard M. O'Brien, Emily M. Hawes, D. P. Claxton, J. K. Oeser
2023Bioscience Reports2 citations Open access
Semantic Scholar
G6PC1 and G6PC2 Influence Glucose-6-Phosphate Flux but not 11β-Hydroxysteroid Dehydrogenase Type 1 Activity
Emily M. Hawes, Kayla A Boortz, J. K. Oeser, Margaret L. O'Rourke +1 more
2023Journal of Molecular Endocrinology1 citations Open access
Semantic Scholar

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R. M. O'Brien×39
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C. A. Svitek×16
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Yingda Wang×12
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J. Hutton×12
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O. McGuinness×11

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Lynley D. Pound×9

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Kristen E. Syring×9

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Jared N. Boustead×7

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