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Takashi Takeshita · SciRah

Researcher profile · Semantic Scholar

Takashi Takeshita

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Takashi Takeshita — researcher profile on SciRah

h-index: 18
Works: 78
Citations: 1,249

Most-cited papers

The ubiquitin E3 ligase activity of BRCA1 and its biological functions
Wenwen Wu, Ayaka Koike, Takashi Takeshita, T. Ohta
2008Cell Division136 citations Open access
Semantic Scholar
Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence
Aiko Sueta, Yutaka Yamamoto, Mai Tomiguchi, Takashi Takeshita +2 more
2017OncoTarget120 citations Open access
Semantic Scholar
Droplet digital polymerase chain reaction assay for screening of ESR1 mutations in 325 breast cancer specimens.
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Toko Inao +4 more
2015Translational Research: The Journal of Laboratory and Clinical Medicine72 citations
Semantic Scholar
Prognostic role of PIK3CA mutations of cell‐free DNA in early‐stage triple negative breast cancer
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Toko Inao +4 more
2015Cancer Science66 citations Open access
Semantic Scholar
Clinical significance of monitoring ESR1 mutations in circulating cell-free DNA in estrogen receptor positive breast cancer patients
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Toko Inao +4 more
2016OncoTarget61 citations Open access
Semantic Scholar
Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mai Tomiguchi +4 more
2017OncoTarget58 citations Open access
Semantic Scholar
Late recurrence of breast cancer is associated with pro-cancerous immune microenvironment in the primary tumor
Takashi Takeshita, Li Yan, M. Asaoka, O. Rashid +1 more
2019Scientific Reports54 citations Open access
Semantic Scholar
Clinical significance of plasma cell-free DNA mutations in PIK3CA, AKT1, and ESR1 gene according to treatment lines in ER-positive breast cancer
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mai Tomiguchi +3 more
2018Molecular Cancer51 citations Open access
Semantic Scholar
Fibroblast growth factor receptor‐1 protein expression is associated with prognosis in estrogen receptor‐positive/human epidermal growth factor receptor‐2‐negative primary breast cancer
Mai Tomiguchi, Yutaka Yamamoto, M. Yamamoto-Ibusuki, L. Goto‐Yamaguchi +7 more
2016Cancer Science47 citations Open access
Semantic Scholar
High expression of polo-like kinase 1 is associated with TP53 inactivation, DNA repair deficiency, and worse prognosis in ER positive Her2 negative breast cancer.
Takashi Takeshita, M. Asaoka, E. Katsuta, Sara J. Photiadis +3 more
2019American journal of translational research46 citations
Semantic Scholar
Comparison of ESR1 Mutations in Tumor Tissue and Matched Plasma Samples from Metastatic Breast Cancer Patients
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mai Tomiguchi +4 more
2017Translational Oncology45 citations Open access
Semantic Scholar
Lenvatinib, an oral multi-kinases inhibitor, -associated hypertension: Potential role of vascular endothelial dysfunction.
D. Sueta, Koichi Suyama, Aiko Sueta, N. Tabata +11 more
2017Atherosclerosis43 citations
Semantic Scholar
High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer
E. Katsuta, Li Yan, Takashi Takeshita, Kerry-Ann McDonald +3 more
2019International Journal of Molecular Sciences41 citations Open access
Semantic Scholar
An Integrative Analysis of PIK3CA Mutation, PTEN, and INPP4B Expression in Terms of Trastuzumab Efficacy in HER2-Positive Breast Cancer
Aiko Sueta, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mitsuhiro Hayashi +3 more
2014PLoS ONE36 citations Open access
Semantic Scholar
The localization of HER4 intracellular domain and expression of its alternately-spliced isoforms have prognostic significance in ER+ HER2- breast cancer
Saori Fujiwara, Mutsuko Yamamoto-Ibusuk, Yutaka Yamamoto, Satoko Yamamoto +5 more
2014OncoTarget30 citations Open access
Semantic Scholar
C6ORF97-ESR1 breast cancer susceptibility locus: influence on progression and survival in breast cancer patients
M. Yamamoto-Ibusuki, Yutaka Yamamoto, Saori Fujiwara, Aiko Sueta +5 more
2014European Journal of Human Genetics29 citations Open access
Semantic Scholar
Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents
Takashi Takeshita, Wenwen Wu, Ayaka Koike, M. Fukuda +1 more
2009Cancer Chemotherapy and Pharmacology25 citations Open access
Semantic Scholar
Therapeutic predictors of neoadjuvant endocrine therapy response in estrogen receptor-positive breast cancer with reference to optimal gene expression profiling
L. Goto‐Yamaguchi, M. Yamamoto-Ibusuki, Yutaka Yamamoto, Yoshitaka Fujiki +4 more
2018Breast Cancer Research and Treatment23 citations
Semantic Scholar
Prevalence of ESR1 E380Q mutation in tumor tissue and plasma from Japanese breast cancer patients
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Aiko Sueta +4 more
2017BMC Cancer17 citations Open access
Semantic Scholar
The Impact of Immunofunctional Phenotyping on the Malfunction of the Cancer Immunity Cycle in Breast Cancer
Takashi Takeshita, T. Torigoe, Li Yan, Jing-Li Huang +2 more
2020Cancers16 citations Open access
Semantic Scholar
Differential role of MACC1 expression and its regulation of the HGF/c‑Met pathway between breast and colorectal cancer.
Aiko Sueta, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mitsuhiro Hayashi +4 more
2015International Journal of Oncology15 citations Open access
Semantic Scholar
Clinical significance of androgen receptor and its phosphorylated form in breast cancer.
Takashi Takeshita, Y. Omoto, M. Yamamoto-Ibusuki, Yutaka Yamamoto +1 more
2013Endocrine-Related Cancer15 citations Open access
Semantic Scholar
Clinical Implications of Occult Metastases and Isolated Tumor Cells in Sentinel and Non-Sentinel Lymph Nodes in Early Breast Cancer Patients: Serial Step Section Analysis with Long-Term Follow-Up
Takashi Takeshita, H. Tsuda, T. Moriya, Tamio Yamasaki +8 more
2012Annals of Surgical Oncology15 citations
Semantic Scholar
Impact of systemic dexamethasone administration on oral mucositis induced by anthracycline-containing regimens in breast cancer treatment
Y. Saito, Y. Takekuma, Takashi Takeshita, T. Oshino +1 more
2022Scientific Reports14 citations Open access
Semantic Scholar
Clinical Relevance of Estrogen Reactivity in the Breast Cancer Microenvironment
Takashi Takeshita, Y. Tokumaru, M. Oshi, Rong-Rong Wu +6 more
2021Frontiers in Oncology14 citations Open access
Semantic Scholar
Development of a Machine Learning-Based Prognostic Model for Hormone Receptor-Positive Breast Cancer Using Nine-Gene Expression Signature
Takashi Takeshita, H. Iwase, Rong-Rong Wu, Danya Ziazadeh +2 more
2023World Journal of Oncology13 citations Open access
Semantic Scholar
Transcriptomic and functional pathway features were associated with survival after pathological complete response to neoadjuvant chemotherapy in breast cancer.
Takashi Takeshita, Yan Li, Xuan Peng, S. Kimbung +4 more
2020American Journal of Cancer Research12 citations
Semantic Scholar
APOBEC3B gene expression as a novel predictive factor for pathological complete response to neoadjuvant chemotherapy in breast cancer
Yoshitaka Fujiki, Yutaka Yamamoto, Aiko Sueta, M. Yamamoto-Ibusuki +4 more
2018OncoTarget11 citations Open access
Semantic Scholar
Factors involved in early lenvatinib dose reduction: a retrospective analysis
Koichi Suyama, Mai Tomiguchi, Takashi Takeshita, Aiko Sueta +4 more
2018Medical Oncology10 citations
Semantic Scholar
Severe Hypertriglyceridemia Induced by Docetaxel: A Novel Case Report
Y. Saito, Y. Takekuma, Takashi Takeshita, M. Sugawara
2021Case Reports in Oncology8 citations Open access
Semantic Scholar
HER2 Gene Amplification in ER-positive HER2 Immunohistochemistry 0 or 1+ Breast Cancer With Early Recurrence
H. Yamashita, N. Ishida, Y. Hatanaka, K. Hagio +6 more
2020Anticancer Research8 citations Open access
Semantic Scholar
ESR1 and PIK3CA mutational status in serum and plasma from metastatic breast cancer patients: A comparative study
Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki, Mai Tomiguchi +2 more
2018Cancer Biomarkers8 citations Open access
Semantic Scholar
High dose of dexamethasone attenuates docetaxel-induced fluid retention in breast cancer treatment
Y. Saito, Ryota Kanno, Y. Takekuma, Takashi Takeshita +2 more
2023Scientific Reports7 citations Open access
Semantic Scholar
Dexamethasone dose-dependently prevents taxane-associated acute pain syndrome in breast cancer treatment
Y. Saito, Y. Takekuma, Takashi Takeshita, T. Oshino +1 more
2023Supportive Care in Cancer7 citations Open access
Semantic Scholar
Analysis of plasma HER2 copy number in cell-free DNA of breast cancer patients: a comparison with HER2 extracellular domain protein level in serum
Qui Shi, Takashi Takeshita, Aiko Sueta, Mai Tomiguchi +5 more
2021Breast Cancer7 citations
Semantic Scholar
Impact of clinical targeted sequencing on endocrine responsiveness in estrogen receptor-positive, HER2-negative metastatic breast cancer
K. Hagio, T. Amano, H. Hayashi, Takashi Takeshita +7 more
2021Scientific Reports7 citations Open access
Semantic Scholar
Clinical features of lenvatinib treatment in elderly patients with advanced thyroid cancer
Koichi Suyama, Saori Fujiwara, Takashi Takeshita, Aiko Sueta +4 more
2017Molecular and clinical oncology7 citations Open access
Semantic Scholar
Impact of systemic dexamethasone dosage on docetaxel-induced oral mucositis in patients with breast cancer
Y. Saito, Y. Takekuma, Takashi Takeshita, T. Oshino +1 more
2023Scientific Reports6 citations Open access
Semantic Scholar
Fulvestrant plus palbociclib in advanced or metastatic hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer after fulvestrant monotherapy: Japan Breast Cancer Research Group-M07 (FUTURE trial)
Kenichi Watanabe, N. Niikura, Y. Kikawa, Marilyn K Oba +13 more
2023Breast Cancer Research and Treatment6 citations Open access
Semantic Scholar
New evidence about thyroid cancer prevalence: prevalence of thyroid cancer in younger and middle-aged Japanese population.
S. Kikuchi, Takashi Takeshita, H. Shibata, K. Hase +1 more
2013Endocrine journal6 citations Open access
Semantic Scholar
Impact of reducing day 1 dexamethasone dose in anthracycline-containing regimens on acute gastrointestinal symptoms associated with breast cancer treatment
Y. Saito, Y. Takekuma, Takashi Takeshita, M. Sugawara
2021Scientific Reports5 citations Open access
Semantic Scholar
Risk Factor Analysis for the Occurrence of Severe Adverse Effects in Eribulin Treatment
Y. Saito, Y. Takekuma, Takashi Takeshita, T. Noguchi +5 more
2022Anticancer Research4 citations
Semantic Scholar
Influence of Dose Reduction of Prophylactic Dexamethasone on Chemotherapy-induced Nausea and Anorexia in Patients Under 55 Years Old Treated With Anthracycline-containing Regimens
Y. Saito, Y. Takekuma, Takashi Takeshita, M. Sugawara
2022Anticancer Research4 citations
Semantic Scholar
[Interstitial Pneumonia Caused by Olaparib during Treatment of Breast Cancer-A Case Report].
Haruna Suzuki, T. Oshino, K. Hagio, Takashi Takeshita +1 more
2020Gan to kagaku ryoho. Cancer & chemotherapy4 citations
Semantic Scholar
dPCR Mutational Analyses in Cell-Free DNA: A Comparison with Tissues.
Takashi Takeshita, H. Iwase
2019Methods in molecular biology4 citations
Semantic Scholar
PTIP Associated protein 1, PA1, Is an Independent Prognostic Factor for Lymphnode Negative Breast Cancer
Takashi Takeshita, M. Yamamoto-Ibusuki, Yutaka Yamamoto, Y. Omoto +4 more
2013PLoS ONE4 citations Open access
Semantic Scholar
Immunohistochemical analysis in ethinylestradiol-treated breast cancers after prior long-term estrogen-deprivation therapy
Y. Omoto, Takashi Takeshita, Yutaka Yamamoto, M. Yamamoto-Ibusuki +5 more
2015SpringerPlus3 citations Open access
Semantic Scholar
Evaluation of a novel medical device for pegfilgrastim administration
T. Aruga, H. Doihara, Y. Yanagita, T. Ishida +11 more
2022Cancer Science2 citations Open access
Semantic Scholar
Differential role of MACC 1 expression and its regulation of the HGF / c ‐ Met pathway between breast and colorectal cancer
Aiko Sueta, Yutaka Yamamoto, MUTSUkO YAMAMOTO-IBUSUkI, Mitsuhiro Hayashi +4 more
20152 citations
Semantic Scholar
Abstract P3-04-15: Ethinylestradiol treatment downregulates ER and upregulates PgR; Immunohistochemical analysis in postmenopausal breast cancer tissues after prior long-term estrogen-deprivation therapy
H. Iwase, Y. Omoto, Takashi Takeshita, M. Yamamoto-Ibusuki +4 more
20152 citations
Semantic Scholar

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H. Iwase×27
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H. Iwase — researcher profile on SciRah
Yutaka Yamamoto×26
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Yutaka Yamamoto — researcher profile on SciRah
Aiko Sueta×23
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Aiko Sueta — researcher profile on SciRah
M. Yamamoto-Ibusuki×22
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Mai Tomiguchi — researcher profile on SciRah

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Y. Omoto — researcher profile on SciRah

Saori Fujiwara×9

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Mitsuhiro Hayashi×8

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Mitsuhiro Hayashi — researcher profile on SciRah

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Y. Saito — researcher profile on SciRah

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Y. Takekuma — researcher profile on SciRah

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K. Takabe — researcher profile on SciRah

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T. Oshino — researcher profile on SciRah