Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

L. Schild · SciRah

Researcher profile · Semantic Scholar

L. Schild

Share profile

L. Schild — researcher profile on SciRah

h-index: 15
Works: 33
Citations: 2,082

Most-cited papers

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
J. Molenaar, J. Koster, D. Zwijnenburg, P. van Sluis +18 more
2012Nature870 citations Open access
Semantic Scholar
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
T. F. Eleveld, D. Oldridge, V. Bernard, J. Koster +42 more
2015Nature Genetics527 citations Open access
Semantic Scholar
Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe.
Fieke Lamers, I. V. D. van der Ploeg, L. Schild, M. E. Ebus +6 more
2011Endocrine-Related Cancer95 citations Open access
Semantic Scholar
Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours.
L. T. Bate-Eya, M. E. Ebus, J. Koster, I. den Hartog +7 more
2014European Journal of Cancer71 citations
Semantic Scholar
Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression.
Fieke Lamers, L. Schild, J. Koster, R. Versteeg +2 more
2012European Journal of Cancer69 citations Open access
Semantic Scholar
Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’
K. Langenberg, M. Meister, J. Bakhuizen, J. Boer +50 more
2022European Journal of Cancer64 citations Open access
Semantic Scholar
High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition
L. T. Bate-Eya, I. den Hartog, I. V. D. van der Ploeg, L. Schild +7 more
2016OncoTarget56 citations Open access
Semantic Scholar
RAS-MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma.
T. F. Eleveld, L. Schild, J. Koster, D. Zwijnenburg +7 more
2018Cancer Research54 citations Open access
Semantic Scholar
Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth.
Fieke Lamers, L. Schild, I. den Hartog, M. E. Ebus +6 more
2012European Journal of Cancer53 citations Open access
Semantic Scholar
Identification of BIRC6 as a novel intervention target for neuroblastoma therapy
Fieke Lamers, L. Schild, J. Koster, F. Speleman +6 more
2012BMC Cancer33 citations Open access
Semantic Scholar
Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies
Waleed M. Kholosy, M. Derieppe, F. van den Ham, K. Ober +12 more
2021Journal of Personalized Medicine31 citations Open access
Semantic Scholar
Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma
M. L. van den Boogaard, Rurika Oka, Anne Hakkert, L. Schild +14 more
2021Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy
Myrthala Moreno-Smith, A. Lakoma, Zaowen Chen, Ling Tao +13 more
2017Clinical Cancer Research26 citations Open access
Semantic Scholar
Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma
Josephine G. M. Strijker, Guillem Pascual-Pasto, Grant P. Grothusen, Yannine J. Kalmeijer +23 more
2024bioRxiv22 citations Open access
Semantic Scholar
High-throughput screening identifies idasanutlin as a resensitizing drug for venetoclax-resistant neuroblastoma cells
Lindy Vernooij, L. T. Bate-Eya, L. Alles, Jasmine Y. Lee +12 more
2021Molecular Cancer Therapeutics16 citations Open access
Semantic Scholar
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine
K. Langenberg, S. V. van Hooff, B. Koopmans, Josephine G. M. Strijker +35 more
2025European Journal of Cancer14 citations Open access
Semantic Scholar
The potential of PARP as a therapeutic target across pediatric solid malignancies
K. Keller, J. Koetsier, L. Schild, V. Amo-Addae +13 more
2023BMC Cancer14 citations Open access
Semantic Scholar
Combined targeting of the p53 and pRb pathway in neuroblastoma does not lead to synergistic responses.
Nil A. Schubert, L. Schild, Stijn van Oirschot, K. Keller +6 more
2020European Journal of Cancer12 citations Open access
Semantic Scholar
Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma
K. Keller, T. F. Eleveld, L. Schild, Kim van den Handel +11 more
2022Frontiers in Oncology10 citations Open access
Semantic Scholar
Two opposing gene expression patterns within ATRX aberrant neuroblastoma
Michael R. van Gerven, L. Schild, Jennemiek van Arkel, B. Koopmans +8 more
2022bioRxiv9 citations Open access
Semantic Scholar
MEK inhibition causes BIM stabilization and increased sensitivity to BCL-2 family member inhibitors in RAS-MAPK-mutated neuroblastoma
T. F. Eleveld, Lindy Vernooij, L. Schild, B. Koopmans +12 more
2023Frontiers in Oncology7 citations Open access
Semantic Scholar
Loss of p16INK4a in neuroblastoma cells induces shift to an immature state with mesenchymal characteristics and increases sensitivity to EGFR inhibitors
Nil A. Schubert, S. V. van Hooff, L. Schild, K. Ober +14 more
2021bioRxiv3 citations Open access
Semantic Scholar
New therapeutic targets in the intrinsic apoptotic pathway in neuroblastoma
Fieke Lamers, L. Schild, I. den Hartog, M. E. Ebus +6 more
20122 citations
Semantic Scholar
Corrigendum to “Implementation of paediatric precision oncology into clinical practice: The individualized therapies for children with cancer program ‘iTHER’” [Eur J Cancer 175 (2022) 311–325]
K. Langenberg, M. T. Meister, J. Bakhuizen, J. Boer +50 more
2025European Journal of Cancer1 citations Open access
Semantic Scholar
MEK inhibition causes Bim stabilization and sensitivity to Bcl2 family member inhibitors in RAS-MAPK mutated neuroblastoma
T. F. Eleveld, Lindy Vernooij, L. Schild, B. Koopmans +8 more
2020bioRxiv1 citations Open access
Semantic Scholar
Abstract A31: Activation of the RAS-MAPK pathway in primary neuroblastoma tumors is associated with poor prognosis
T. F. Eleveld, L. Schild, M. E. Ebus, P. van Sluis +5 more
20161 citations
Semantic Scholar
Abstract 2980: Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
D. Oldridge, T. F. Eleveld, V. Bernard, Jan Koster +41 more
20151 citations
Semantic Scholar
A Common Genomic Denominator for Neuroblastoma and Differentiated Thyroid Carcinoma? A Case Series in Children.
S. Clement, J. Koster, R. Kuiper, G. Tytgat +7 more
2022Clinics in oncology0 citations Open access
Semantic Scholar
Abstract A49: Combined targeting of the p53 and pRb pathway in neuroblastoma
Nil A. Schubert, L. Schild, Stijn van Oirschot, K. Keller +6 more
20200 citations
Semantic Scholar
Abstract B09: MCL-1 inhibition improves ABT199 efficacy for BCL-2-dependent neuroblastoma
L. T. Bate-Eya, I. den Hartog, I. V. D. van der Ploeg, L. Schild +5 more
20160 citations
Semantic Scholar
Abstract B41: Whole genome sequencing identifies tumor evolution events in relapse neuroblastoma
T. F. Eleveld, L. Schild, J. Koster, D. Zwijnenburg +6 more
20140 citations
Semantic Scholar
L04.05 TARGETED DRUG DEVELOPMENT IN PEDIATRIC CANCER DESPITE A LOW FREQUENCY OF TUMOR DRIVING MUTATIONS
J. Molenaar, J. Koster, M. E. Ebus, D. Zwijnenburg +6 more
20130 citations Open access
Semantic Scholar
New therapeutic targets in the intrinsic apoptotic pathway in neuroblastoma
Fieke Lamers, L. Schild, J. Koster, F. Speleman +5 more
20120 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Molenaar×31
Invite
J. Molenaar — researcher profile on SciRah
J. Koster×20
Invite
J. Koster — researcher profile on SciRah
R. Versteeg×20
Invite
R. Versteeg — researcher profile on SciRah
M. E. Ebus×16
Invite
M. E. Ebus — researcher profile on SciRah

×15

Invite

H. Caron — researcher profile on SciRah

Invite

M. Dolman — researcher profile on SciRah

D. Zwijnenburg×10

Invite

D. Zwijnenburg — researcher profile on SciRah

P. van Sluis×9

Invite

P. van Sluis — researcher profile on SciRah

Invite

B. Koopmans — researcher profile on SciRah

E. M. Westerhout×8

Invite

E. M. Westerhout — researcher profile on SciRah

T. F. Eleveld×8

Invite

T. F. Eleveld — researcher profile on SciRah

Fieke Lamers×7

Invite

Fieke Lamers — researcher profile on SciRah