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Harald Hartweger · SciRah

Researcher profile · Semantic Scholar

Harald Hartweger

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Harald Hartweger — researcher profile on SciRah

h-index: 13
Works: 42
Citations: 3,055

Most-cited papers

Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals
D. Robbiani, C. Gaebler, Frauke Muecksch, Julio C. C. Lorenzi +42 more
2020Nature1,856 citations Open access
Semantic Scholar
Antibody affinity shapes the choice between memory and germinal center B cell fates
Charlotte Viant, G. H. J. Weymar, A. Escolano, Spencer T. Chen +4 more
2020Cell207 citations Open access
Semantic Scholar
Protein amounts of the MYC transcription factor determine germinal center B cell division capacity
Shlomo Finkin, Harald Hartweger, Thiago Y. Oliveira, Ervin E. Kara +1 more
2019Immunity157 citations Open access
Semantic Scholar
Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals
D. Robbiani, C. Gaebler, Frauke Muecksch, Julio C. C. Lorenzi +42 more
2020bioRxiv142 citations Open access
Semantic Scholar
HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells
Harald Hartweger, A. McGuire, Marcel Horning, Justin J. Taylor +7 more
2019Journal of Experimental Medicine109 citations Open access
Semantic Scholar
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope
C. Barnes, H. Gristick, N. Freund, A. Escolano +6 more
2018Nature Communications107 citations Open access
Semantic Scholar
Anti–HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity
P. Dosenovic, Ervin E. Kara, Anna-Klara Pettersson, A. McGuire +5 more
2018Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Dynamic Regulation of Tfh Selection During the Germinal Center Reaction
Julia Merkenschlager, Shlomo Finkin, Victor A. Ramos, Julia Kraft +9 more
2021Nature85 citations Open access
Semantic Scholar
Continuous Germinal Center Invasion Contributes to the Diversity of the Immune Response
Thomas Hägglöf, M. Cipolla, Maximilian Loewe, Spencer T. Chen +10 more
2022Cell82 citations Open access
Semantic Scholar
Regulated somatic hypermutation enhances antibody affinity maturation
Julia Merkenschlager, Andrew G. T. Pyo, G. S. Silva Santos, Dennis J. Schaefer-Babajew +5 more
2025Nature48 citations Open access
Semantic Scholar
Distinct gene expression by expanded clones of quiescent memory CD4+ T cells harboring intact latent HIV-1 proviruses
G. H. J. Weymar, Y. Bar-On, Thiago Y. Oliveira, C. Gaebler +7 more
2022bioRxiv36 citations Open access
Semantic Scholar
Anti-idiotypic antibodies elicit anti-HIV-1–specific B cell responses
P. Dosenovic, Anna-Klara Pettersson, A. Wall, E. S. Thientosapol +13 more
2019Journal of Experimental Medicine26 citations Open access
Semantic Scholar
CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals
H. Gristick, Harald Hartweger, Maximilian Loewe, Jelle van Schooten +27 more
2022bioRxiv24 citations Open access
Semantic Scholar
B cell–intrinsic requirement for WNK1 kinase in antibody responses in mice
D. Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham +7 more
2023Journal of Experimental Medicine13 citations Open access
Semantic Scholar
Gene Editing of Primary Rhesus Macaque B Cells
Harald Hartweger, R. Gautam, Y. Nishimura, Fabian Schmidt +5 more
2023Journal of Visualized Experiments10 citations Open access
Semantic Scholar
Antibody-mediated diversification of primary and secondary humoral immune responses
Dennis J. Schaefer-Babajew, Laurine Binet, G. S. Silva Santos, Chiara Ruprecht +12 more
2026Journal of Experimental Medicine6 citations Open access
Semantic Scholar
Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes
H. Gristick, Harald Hartweger, Yoshiaki Nishimura, E. Gavor +11 more
2025Journal of Experimental Medicine6 citations Open access
Semantic Scholar
B lymphocyte protein factories produced by hematopoietic stem cell gene editing.
Harald Hartweger, Chiara Ruprecht, Kai-Hui Yao, P. Laffont +25 more
2026Science5 citations Open access
Semantic Scholar
WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses
Joshua Biggs O'May, Lesley Vanes, Leonard L. de Boer, D. A. Lewis +6 more
2023bioRxiv5 citations Open access
Semantic Scholar
Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates
Lachlan P. Deimel, Yoshiaki Nishimura, G. S. Silva Santos, Viren A. Baharani +11 more
2025Cell Reports4 citations Open access
Semantic Scholar
Tissue-specific clonal selection and differentiation of CD4+ T cells during infection
R. Parsa, Helder C. Assis, Tiago B. R. de Castro, Gabriella Lima Dos Reis +4 more
2026Nature Immunology3 citations Open access
Semantic Scholar
B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes.
Pengcheng Zhou, Harald Hartweger, Andrew J. MacLean, Victor A. Ramos +5 more
2026Immunity3 citations Open access
Semantic Scholar
Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes
H. Gristick, Harald Hartweger, Yoshiaki Nishimura, E. Gavor +11 more
2025bioRxiv3 citations
Semantic Scholar
Tissue-specific clonal selection and differentiation of CD4+ T cells during infection
R. Parsa, Helder C. Assis, Tiago B. R. de Castro, Gabriella Lima dos Reis +4 more
2025bioRxiv3 citations Open access
Semantic Scholar
Continuous germinal center invasion contributes to the diversity of the immune response.
Thomas Hägglöf, M. Cipolla, Maximilian Loewe, Spencer T. Chen +11 more
2024Cell3 citations Open access
Semantic Scholar
CRISPR comes a-knock-in to reprogram antibodies in vivo
Harald Hartweger, M. Nussenzweig
2022Nature Biotechnology3 citations
Semantic Scholar
B Lymphocyte Protein Factories produced by Hematopoietic Stem Cell Gene Editing
Harald Hartweger, Chiara Ruprecht, Kai-Hui Yao, P. Laffont +25 more
2026bioRxiv2 citations Open access
Semantic Scholar
B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes
Pengcheng Zhou, Harald Hartweger, Andrew J. MacLean, Victor A. Ramos +5 more
2025bioRxiv2 citations
Semantic Scholar
Biophysical properties of IgD determine thresholds for self-tolerance and selection into germinal centers
Lachlan P. Deimel, Ryan A. Brady, A. Goychuk, G. S. Silva Santos +14 more
2026bioRxiv1 citations Open access
Semantic Scholar
Clonal Expansion and Diversification of Germinal Center and Memory B Cell Responses to Booster Immunization in Primates
Lachlan P. Deimel, Yoshiaki Nishimura, G. S. Silva Santos, Viren A. Baharani +11 more
2025bioRxiv1 citations Open access
Semantic Scholar
Engineering HIV Immunogens to Elicit IOMA-like Antibodies Targeting the CD4 Binding Site
H. Gristick, Jelle van Schooten, Harald Hartweger, M. Abernathy +5 more
20181 citations
Semantic Scholar
Resolving the Functional Significance of BRCA1 RING Domain Missense Substitutions
D. Robbiani, C. Gaebler, Frauke Muecksch, Julio C. C. Lorenzi +42 more
2016bioRxiv1 citations Open access
Semantic Scholar
One-step generation of TCR knock-in mice targeted to the TCRβ locus results in functional mature T lymphocytes
Jana Bilanovic, Juliana Bortolatto, Susu Duan, Valgerdur Bjørnsdottir +11 more
2026bioRxiv0 citations Open access
Semantic Scholar
Mechanisms of antibody-mediated enhancement of immune responses.
M. Cipolla, Andrew J. MacLean, Brianna Hernandez, G. S. Silva Santos +7 more
2026Journal of Experimental Medicine0 citations
Semantic Scholar
One-step generation of T-cell receptor knock-in mice in the TCRβ locus
Jana Bilanovic, Juliana Bortolatto, Susu Duan, Valgerdur Bjørnsdottir +11 more
2026EMBO Journal0 citations Open access
Semantic Scholar
B cells sustain tumor-specific CD4 T cells to promote response to PD-1 targeted therapy
A. Vaidya, Étienne Humblin, Nataliya Prokhnevska, Verena van der Heide +19 more
2026bioRxiv0 citations Open access
Semantic Scholar
Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses
M. Cipolla, Andrew J. MacLean, Brianna Hernandez, G. S. Silva Santos +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
Antibody Mediated Diversification of Primary and Secondary Immune Responses
Dennis J. Schaefer-Babajew, L. Binet, G. S. Silva Santos, Chiara Ruprecht +11 more
2025bioRxiv0 citations
Semantic Scholar
Abstract B113: Protective serum responses by CRISPR/Cas9-edited primary B cells expressing antibodies of choice
Harald Hartweger, M. Jankovic, M. Nussenzweig
2019Novel Vaccine Platforms and Combinations0 citations
Semantic Scholar
Antigen-specific humoral immune responses by CRISPR/Cas9-edited B cells
Harald Hartweger, A. McGuire, Marcel Horning, Justin J. Taylor +7 more
2019bioRxiv0 citations Open access
Semantic Scholar
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope
C. Barnes, H. Gristick, N. Freund, A. Escolano +6 more
2018Nature Communications0 citations Open access
Semantic Scholar
Abstract B144: Elucidating germinal center B cell metabolic states and their influence on selection
Harald Hartweger, Shlomo Finkin, M. Nussenzweig
20160 citations
Semantic Scholar

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