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Y. Nishimura · SciRah

Researcher profile · Semantic Scholar

Y. Nishimura

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Y. Nishimura — researcher profile on SciRah

h-index: 32
Works: 58
Citations: 5,290

Most-cited papers

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
J. Mattapallil, D. Douek, B. Hill, Y. Nishimura +2 more
2005Nature1,298 citations
Semantic Scholar
ANTIBODY MEDIATED IMMUNOTHERAPY OF MACAQUES CHRONICALLY INFECTED WITH SHIV SUPPRESSES VIREMIA
M. Shingai, Y. Nishimura, F. Klein, H. Mouquet +9 more
2013Nature484 citations Open access
Semantic Scholar
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques
M. Shingai, Olivia K. Donau, R. Plishka, A. Buckler-White +17 more
2014Journal of Experimental Medicine332 citations Open access
Semantic Scholar
A SINGLE INJECTION OF ANTI-HIV-1 ANTIBODIES PROTECTS AGAINST REPEATED SHIV CHALLENGES
R. Gautam, Y. Nishimura, A. Pegu, M. Nason +12 more
2016Nature311 citations Open access
Semantic Scholar
EARLY ANTIBODY THERAPY CAN INDUCE LONG LASTING IMMUNITY TO SHIV
Y. Nishimura, R. Gautam, Tae-Wook Chun, Reza Sadjadpour +15 more
2017Nature305 citations Open access
Semantic Scholar
Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization
I. Georgiev, N. Doria-Rose, Tongqing Zhou, Young Do Kwon +21 more
2013Science233 citations Open access
Semantic Scholar
Determination of a Statistically Valid Neutralization Titer in Plasma That Confers Protection against Simian-Human Immunodeficiency Virus Challenge following Passive Transfer of High-Titered Neutralizing Antibodies
Y. Nishimura, T. Igarashi, N. Haigwood, Reza Sadjadpour +4 more
2002Journal of Virology175 citations Open access
Semantic Scholar
Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses.
Y. Nishimura, T. Igarashi, Olivia K. Donau, A. Buckler-White +6 more
2004Proceedings of the National Academy of Sciences of the United States of America158 citations Open access
Semantic Scholar
Transfer of neutralizing IgG to macaques 6 h but not 24 h after SHIV infection confers sterilizing protection: Implications for HIV-1 vaccine development
Y. Nishimura, T. Igarashi, N. Haigwood, Reza Sadjadpour +5 more
2003Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
Resting naïve CD4+ T cells are massively infected and eliminated by X4-tropic simian–human immunodeficiency viruses in macaques
Y. Nishimura, Charles R. Brown, J. Mattapallil, T. Igarashi +5 more
2005Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection
Takuya Yamamoto, R. Lynch, R. Gautam, Rodrigo Matus-Nicodemos +15 more
2015Science Translational Medicine116 citations
Semantic Scholar
A single injection of crystallizable fragment domain- modified antibodies elicits durable protection from SHIV infection
R. Gautam, Y. Nishimura, Natalie Gaughan, A. Gazumyan +7 more
2018Nature Medicine112 citations Open access
Semantic Scholar
Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque
L. Walker, D. Sok, Y. Nishimura, Olivia K. Donau +11 more
2011Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Generation of the Pathogenic R5-Tropic Simian/Human Immunodeficiency Virus SHIVAD8 by Serial Passaging in Rhesus Macaques
Y. Nishimura, M. Shingai, R. Willey, Reza Sadjadpour +9 more
2010Journal of Virology90 citations Open access
Semantic Scholar
Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization
J. Francica, Zizhang Sheng, Zhen-Hai Zhang, Y. Nishimura +25 more
2015Nature Communications89 citations Open access
Semantic Scholar
Most rhesus macaques infected with the CCR5-tropic SHIVAD8 generate cross-reactive antibodies that neutralize multiple HIV-1 strains
M. Shingai, Olivia K. Donau, S. Schmidt, R. Gautam +9 more
2012Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
OF MICE, MACAQUES AND MEN: BROADLY NEUTRALIZING ANTIBODY IMMUNOTHERAPY FOR HIV-1
Y. Nishimura, Malcolma Martin
2017Cell Host and Microbe75 citations Open access
Semantic Scholar
Interspecies Transmission of Feline Immunodeficiency Virus from the Domestic Cat to the Tsushima Cat (Felis bengalensis euptilura) in the Wild
Y. Nishimura, Y. Goto, K. Yoneda, Y. Endo +12 more
1999Journal of Virology74 citations Open access
Semantic Scholar
Short- and Long-Term Clinical Outcomes in Rhesus Monkeys Inoculated with a Highly Pathogenic Chimeric Simian/Human Immunodeficiency Virus
Y. Endo, T. Igarashi, Y. Nishimura, C. Buckler +4 more
2000Journal of Virology71 citations Open access
Semantic Scholar
Unique Pathology in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques Is Consistent with a Pathogenesis Distinct from That of Classical AIDS
Charles R. Brown, M. Czapiga, Juraj Kabat, Q. Dang +4 more
2007Journal of Virology68 citations Open access
Semantic Scholar
Noninvasive in vivo imaging of CD4 cells in simian-human immunodeficiency virus (SHIV)-infected nonhuman primates.
M. Di Mascio, C. Paik, J. Carrasquillo, J. Maeng +11 more
2009Blood65 citations Open access
Semantic Scholar
Sequential immunization of macaques elicits heterologous, neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env
A. Escolano, H. Gristick, R. Gautam, A. T. DeLaitsch +24 more
2021Science Translational Medicine58 citations Open access
Semantic Scholar
Loss of Naïve Cells Accompanies Memory CD4+ T-Cell Depletion during Long-Term Progression to AIDS in Simian Immunodeficiency Virus-Infected Macaques
Y. Nishimura, T. Igarashi, A. Buckler-White, C. Buckler +8 more
2006Journal of Virology56 citations Open access
Semantic Scholar
Rapid and Irreversible CD4+ T-Cell Depletion Induced by the Highly Pathogenic Simian/Human Immunodeficiency Virus SHIVDH12R Is Systemic and Synchronous
T. Igarashi, Charles R. Brown, R. Byrum, Y. Nishimura +7 more
2002Journal of Virology54 citations Open access
Semantic Scholar
Pathogenicity and Mucosal Transmissibility of the R5-Tropic Simian/Human Immunodeficiency Virus SHIVAD8 in Rhesus Macaques: Implications for Use in Vaccine Studies
R. Gautam, Y. Nishimura, Wendy R. Lee, Olivia K. Donau +9 more
2012Journal of Virology52 citations Open access
Semantic Scholar
Immunotherapy during the acute SHIV infection of macaques confers long-term suppression of viremia
Y. Nishimura, Olivia K. Donau, Joana Dias, S. Ferrando-Martínez +8 more
2020Journal of Experimental Medicine51 citations Open access
Semantic Scholar
Genetic heterogeneity of env gene of feline immunodeficiency virus obtained from multiple districts in Japan.
Y. Nishimura, Y. Goto, H. Pang, Y. Endo +5 more
1998Virus Research49 citations
Semantic Scholar
High frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections
Y. Nishimura, Reza Sadjadpour, J. Mattapallil, T. Igarashi +5 more
2009Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Neutralizing Antibody Titers Conferring Protection to Macaques from a Simian/Human Immunodeficiency Virus Challenge Using the TZM-bl Assay
R. Willey, M. Nason, Y. Nishimura, D. Follmann +1 more
2010AIDS Research and Human Retroviruses44 citations Open access
Semantic Scholar
Association of Progressive CD4+ T Cell Decline in SIV Infection with the Induction of Autoreactive Antibodies
T. Kuwata, Y. Nishimura, Sonya Whitted, I. Ourmanov +6 more
2009PLoS Pathogens39 citations Open access
Semantic Scholar
CD8+ and CD20+ Lymphocytes Cooperate To Control Acute Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys: Modulation by Major Histocompatibility Complex Genotype
H. Mao, B. Lafont, T. Igarashi, Y. Nishimura +5 more
2005Journal of Virology38 citations Open access
Semantic Scholar
Expansion of CD8alpha+beta- cells in cats infected with feline immunodeficiency virus.
M. Shimojima, T. Miyazawa, M. Kohmoto, Y. Ikeda +4 more
1998Journal of General Virology37 citations Open access
Semantic Scholar
Association of Plasma Viral RNA Load with Prognosis in Cats Naturally Infected with Feline Immunodeficiency Virus
Y. Goto, Y. Nishimura, K. Baba, T. Mizuno +4 more
2002Journal of Virology31 citations Open access
Semantic Scholar
Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic
H. Imamichi, T. Igarashi, T. Imamichi, Olivia K. Donau +6 more
2002Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Molecular cloning of equine interleukin-1α and -β cDNAs
H. Kato, T. Ohashi, Noriko Nakamura, Y. Nishimura +4 more
199527 citations
Semantic Scholar
The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells
M. Shingai, Sarah Welbourn, J. Brenchley, P. Acharya +7 more
2015PLoS Pathogens25 citations Open access
Semantic Scholar
CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals
H. Gristick, Harald Hartweger, Maximilian Loewe, Jelle van Schooten +27 more
2022bioRxiv24 citations Open access
Semantic Scholar
Early Control of Highly Pathogenic Simian Immunodeficiency Virus/Human Immunodeficiency Virus Chimeric Virus Infections in Rhesus Monkeys Usually Results in Long-Lasting Asymptomatic Clinical Outcomes
T. Igarashi, Y. Endo, Y. Nishimura, C. Buckler +6 more
2003Journal of Virology23 citations Open access
Semantic Scholar
Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor
Y. Nishimura, J. N. Francis, Olivia K. Donau, Eric Jesteadt +6 more
2020Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Emergence of gp120 V3 Variants Confers Neutralization Resistance in an R5 Simian-Human Immunodeficiency Virus-Infected Macaque Elite Neutralizer That Targets the N332 Glycan of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein
Reza Sadjadpour, Olivia K. Donau, M. Shingai, A. Buckler-White +4 more
2013Journal of Virology16 citations Open access
Semantic Scholar
A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch
Zi-Jun Wang, C. Barnes, R. Gautam, J. C. Cetrulo Lorenzi +15 more
2020bioRxiv14 citations Open access
Semantic Scholar
Initiation of Antiretroviral Therapy 48 Hours after Infection with Simian Immunodeficiency Virus Potently Suppresses Acute-Phase Viremia and Blocks the Massive Loss of Memory CD4+ T Cells but Fails To Prevent Disease
M. Kubo, Y. Nishimura, M. Shingai, Wendy R. Lee +5 more
2009Journal of Virology13 citations Open access
Semantic Scholar
Recombination-Mediated Changes in Coreceptor Usage Confer an Augmented Pathogenic Phenotype in a Nonhuman Primate Model of HIV-1-Induced AIDS
Y. Nishimura, M. Shingai, Wendy R. Lee, Reza Sadjadpour +7 more
2011Journal of Virology11 citations Open access
Semantic Scholar
Gene Editing of Primary Rhesus Macaque B Cells
Harald Hartweger, R. Gautam, Y. Nishimura, Fabian Schmidt +5 more
2023Journal of Visualized Experiments10 citations Open access
Semantic Scholar
Molecular cloning and sequencing of feline stromal cell‐derived factor‐1α and β
Y. Nishimura, T. Miyazawa, Y. Ikeda, Y. Izumiya +5 more
199810 citations
Semantic Scholar
The Acute HIV Infection: Implications For Intervention, Prevention and Development of an Effective AIDS Vaccine
Y. Nishimura, Malcolma Martin
2011Current Opinion in Virology9 citations Open access
Semantic Scholar
Although Macrophage-Tropic Simian/Human Immunodeficiency Viruses Can Exhibit a Range of Pathogenic Phenotypes, a Majority of Isolates Induce No Clinical Disease in Immunocompetent Macaques
T. Igarashi, Olivia K. Donau, H. Imamichi, Y. Nishimura +6 more
2007Journal of Virology6 citations Open access
Semantic Scholar
Genomic structure of the bovine mb-1 gene encoding the Ig-alpha subunit of the B cell antigen receptor complex.
H. Youn, K. Cho, Y. Nishimura, R. Goitsuka +3 more
1997Veterinary Immunology and Immunopathology6 citations
Semantic Scholar
Concordance of immunological events between intrarectal and intravenous SHIVAD8-EO infection when assessed by Fiebig-equivalent staging.
Joana Dias, G. Fabozzi, Kylie March, M. Asokan +12 more
2021Journal of Clinical Investigation5 citations Open access
Semantic Scholar
Molecular cloning and sequencing of feline stromal cell-derived factor-1 alpha and beta.
Y. Nishimura, T. Miyazawa, Y. Ikeda, Y. Izumiya +5 more
1998European journal of immunogenetics5 citations
Semantic Scholar

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A. Buckler-White×25
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T. Igarashi — researcher profile on SciRah

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