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Vik Meadows · SciRah

Researcher profile · Semantic Scholar

Vik Meadows

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Vik Meadows — researcher profile on SciRah

h-index: 19
Works: 61
Citations: 784

Most-cited papers

Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
M. Awoniyi, Jeremy R. Wang, Billy Ngo, Vik Meadows +19 more
2022Gut110 citations Open access
Semantic Scholar
The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators
L. Pham, L. Baiocchi, L. Kennedy, Keisaku Sato +8 more
2020Journal of Pineal Research56 citations Open access
Semantic Scholar
Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling
Vik Meadows, L. Kennedy, B. Ekser, Konstantina Kyritsi +10 more
2021Hepatology54 citations Open access
Semantic Scholar
Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet
L. Kennedy, Vik Meadows, A. Sybenga, J. Demieville +13 more
2021Hepatology51 citations Open access
Semantic Scholar
Mast cells (MCs) induce ductular reaction mimicking liver injury in mice via MC-derived TGF-β1 signaling
Konstantina Kyritsi, L. Kennedy, Vik Meadows, L. Hargrove +8 more
2020Hepatology39 citations Open access
Semantic Scholar
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC)
Tianhao Zhou, Konstantina Kyritsi, N. Wu, H. Francis +17 more
2019EBioMedicine36 citations Open access
Semantic Scholar
Biliary Epithelial Senescence in Liver Disease: There Will Be SASP
Vik Meadows, L. Baiocchi, Debjyoti Kundu, Keisaku Sato +7 more
2021Frontiers in Molecular Biosciences33 citations Open access
Semantic Scholar
Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice
Vik Meadows, L. Kennedy, L. Hargrove, J. Demieville +10 more
2019Biochimica et Biophysica Acta - Molecular Basis of Disease32 citations Open access
Semantic Scholar
Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes.
L. Kennedy, G. Carpino, Travis M. Owen, Ludovica Ceci +14 more
2022Journal of Hepatology29 citations
Semantic Scholar
Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases
Vik Meadows, L. Kennedy, Debjyoti Kundu, G. Alpini +1 more
2020Frontiers in Medicine29 citations Open access
Semantic Scholar
The Dynamic Interplay between Mast Cells, Aging/Cellular Senescence and Liver Disease.
Debjyoti Kundu, L. Kennedy, Vik Meadows, L. Baiocchi +2 more
2020Gene Expression26 citations Open access
Semantic Scholar
Inhibition of secretin/secretin receptor axis ameliorates non-alcoholic fatty liver disease phenotypes
Li-Xian Chen, N. Wu, L. Kennedy, H. Francis +12 more
2021Hepatology25 citations Open access
Semantic Scholar
p16 INK4A Drives Non-Alcoholic Fatty Liver Disease Phenotypes in High Fat Diet Fed Mice via Biliary E2F1/FOXO1/IGF-1 Signaling
Debjyoti Kundu, L. Kennedy, Tianhao Zhou, B. Ekser +13 more
2023Hepatology24 citations Open access
Semantic Scholar
Mast cells in liver disease progression: An update on current studies and implications
L. Pham, L. Kennedy, L. Baiocchi, Vik Meadows +8 more
2021Hepatology24 citations Open access
Semantic Scholar
The Functional Role of the Secretin/Secretin Receptor Signaling During Cholestatic Liver Injury
N. Wu, L. Baiocchi, Tianhao Zhou, L. Kennedy +17 more
2020Hepatology24 citations Open access
Semantic Scholar
FXR and NASH: an avenue for tissue-specific regulation
Zakiyah R. Henry, Vik Meadows, Grace L. Guo
2023Hepatology Communications23 citations Open access
Semantic Scholar
MT1 but not MT2 melatonin receptor knockout decreases biliary damage and liver fibrosis during cholestatic liver injury
N. Wu, G. Carpino, Ludovica Ceci, L. Baiocchi +14 more
2021Hepatology23 citations Open access
Semantic Scholar
Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease
Tianhao Zhou, Debjyoti Kundu, Jonathan Robles-Linares, Vik Meadows +7 more
2021Cells23 citations Open access
Semantic Scholar
Biliary damage and liver fibrosis are ameliorated in a novel mouse model lacking l-histidine decarboxylase/histamine signaling
L. Kennedy, Vik Meadows, J. Demieville, L. Hargrove +9 more
2020Laboratory Investigation21 citations Open access
Semantic Scholar
Molecular Mechanisms Linking Risk Factors to Cholangiocarcinoma Development
Ludovica Ceci, Tianhao Zhou, I. Lenci, Vik Meadows +12 more
2022Cancers13 citations Open access
Semantic Scholar
H2 histamine receptor Vivo-Morpholino treatment ameliorates large bile duct damage in mice deficient in ATP binding cassette subfamily B member 4 (Abcb4-/-) via down-regulation of cAMP/ERK signaling.
L. Kennedy, Vik Meadows, Konstantina Kyritsi, L. Pham +10 more
2020American Journal of Pathology13 citations Open access
Semantic Scholar
RETRACTED: The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling
Romina Mancinelli, Ludovica Ceci, L. Kennedy, H. Francis +14 more
2022Cells12 citations Open access
Semantic Scholar
Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?
L. Baiocchi, I. Lenci, M. Milana, L. Kennedy +8 more
2021Cells11 citations Open access
Semantic Scholar
Loss of Apical Sodium Bile Acid Transporter Disrupts Bile Acid Circulation and Reduces Biliary Damage in Cholangitis.
Vik Meadows, Corinn N. Marakovits, B. Ekser, Debjyoti Kundu +16 more
2022American Journal of Physiology - Gastrointestinal and Liver Physiology10 citations
Semantic Scholar
Alcoholic liver disease and mast cells: What's your gut got to do with it?
Julie Ann Tolefree, A. J. Garcia, Jenee Farrell, Vik Meadows +6 more
2019Liver Research10 citations Open access
Semantic Scholar
Mast cells selectively target large cholangiocytes during biliary injury via H2HR‐mediated cAMP/pERK1/2 signaling
Tianhao Zhou, Vik Meadows, Debjyoti Kundu, Konstantina Kyritsi +11 more
2022Hepatology Communications9 citations Open access
Semantic Scholar
Knockout of the tachykinin receptor 1 in the Mdr2-/- mouse model of primary sclerosing cholangitis reduces biliary damage and liver fibrosis.
Ludovica Ceci, H. Francis, Tianhao Zhou, Thao Giang +16 more
2020American Journal of Pathology9 citations Open access
Semantic Scholar
FXR Friend-ChIPs in the Enterohepatic System
Vik Meadows, Zhen-Ning Yang, Veronia Basaly, Grace L. Guo
2023Seminars in liver disease (Print)7 citations Open access
Semantic Scholar
Doublecortin-Like Kinase Protein 1 in Cholangiocarcinoma: Is This the Biomarker and Target We Have Been Looking For?
Vik Meadows, H. Francis
2020Hepatology4 citations Open access
Semantic Scholar
Amelioration of Large Bile Duct Damage by Histamine-2 Receptor Vivo-Morpholino Treatment
L. Kennedy, Vik Meadows, Konstantina Kyritsi, L. Pham +10 more
4 citations
Semantic Scholar
Sa380 KNOCKDOWN OF P16 IMPROVES MAST CELL (MC)-MEDIATED BILIARY SENESCENCE AND NAFLD PHENOTYPES IN A DIET-INDUCED RODENT MODEL
Debjyoti Kundu, L. Kennedy, Vik Meadows, Tianhao Zhou +6 more
20212 citations
Semantic Scholar
MicroRNAs and cholangiocarcinoma: elucidating the effects of tiny giants
Vik Meadows, H. Francis
2018AME Medical Journal2 citations Open access
Semantic Scholar
RETRACTED: Mancinelli et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells 2022, 11, 1591
Romina Mancinelli, Ludovica Ceci, L. Kennedy, Heather Francis +14 more
2026Cells0 citations
Semantic Scholar
Microbiome Targeted Therapies for Primary Sclerosing Cholangitis.
Matthew D. Carson, Vik Meadows, Kari Nejak-Bowen
2026Seminars in liver disease (Print)0 citations Open access
Semantic Scholar
Retraction: Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2-/- mice and human cholangiocarcinoma tumorigenesis.
L. Kennedy, L. Hargrove, J. Demieville, Walker Karstens +10 more
2025Hepatology0 citations
Semantic Scholar
Tu1297: MELATONIN RECEPTOR 1A (MT1) KNOCKOUT DECREASES BILIARY DAMAGE AND LIVER STEATOSIS VIA DOWNREGULATION OF MIR-200B IN HIGH FAT DIET (HFD) MODEL OF NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)
Li-Xian Chen, L. Kennedy, Ludovica Ceci, B. Ekser +11 more
2022Gastroenterology0 citations
Semantic Scholar
The protective effects of estrogen on biliary and liver damage are independent of ER‐β signaling in female Mdr2‐/‐ mice
Travis M. Owen, Konstantina Kyritsi, Li-Xian Chen, Ludovica Ceci +5 more
2022The FASEB Journal0 citations
Semantic Scholar
Tu1316: CROMOLYN SODIUM AMELIORATES MAST CELL(MC)-MEDIATED HEPATIC DAMAGE IN A MURINE MODEL OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)
Debjyoti Kundu, Vik Meadows, Tianhao Zhou, L. Kennedy +5 more
2022Gastroenterology0 citations
Semantic Scholar
Mast Cell (MC)‐Induced Cholestasis is Dependent on Apical Sodium Bile Acid Transporter (ASBT) Expression
Vik Meadows, Debjyoti Kundu, Tianhao Zhou, Travis M. Owen +6 more
2022The FASEB Journal0 citations
Semantic Scholar
Mast Cells Contribute to Hepatic Neurokinin1 Receptor Signaling, Subsequent Biliary Damage and Peribiliary Fibrosis Via TGF‐β1 Signaling in MDR2‐/‐ Mouse Model of Primary Scelrosing Cholangitis
Debjyoti Kundu, Tianhao Zhou, Vik Meadows, L. Kennedy +5 more
2022The FASEB Journal0 citations
Semantic Scholar
Mo1264: INHIBITION OF TRANSFORMING GROWTH FACTOR BETA 1 (TGFβ1) BY VIVO-MORPHOLINO (VM) AMELIORATES CHOLESTASIS IN THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC)
Li-Xian Chen, Tianhao Zhou, Debjyoti Kundu, Vik Meadows +7 more
2022Gastroenterology0 citations
Semantic Scholar
377: INHIBITION OF IL-33/ST2 SIGNALING REDUCES MAST CELL (MC)-INDUCED BILIARY DAMAGE AND PHENOTYPES OF PRIMARY SCLEROSING CHOLANGITIS (PSC) IN MDR2 MICE
Tianhao Zhou, Debjyoti Kundu, L. Kennedy, Vik Meadows +7 more
2022Gastroenterology0 citations
Semantic Scholar
85 MAST CELLS REGULATE CHOLESTATIC LIVER INJURY AND INTESTINAL BILE ACID SIGNALING VIA MODIFICATION OF FXR/FGF15 AXIS
Vik Meadows, L. Kennedy, Debjyoti Kundu, Konstantina Kyritsi +7 more
20210 citations
Semantic Scholar
ASBT Vivo‐Morpholino Decreases Hepatic Mast Cell, Fibrosis and Biliary Senescence in Mdr2‐/‐ Mice
Vik Meadows, H. Francis
2021The FASEB Journal0 citations
Semantic Scholar
86 LONG-TERM SECRETIN TREATMENT RESTORES THE DUCTULO-CANALICULAR JUNCTIONS (DCJ) AND AMELIORATES BILIARY DAMAGE AND LIVER FIBROSIS IN A MODEL OF LATE-STAGE PRIMARY BILIARY CHOLANGITIS (PBC).
L. Kennedy, G. Carpino, Ludovica Ceci, H. Francis +11 more
20210 citations
Semantic Scholar
87 DIFFERENTIAL EFFECTS OF MELATONIN AND IL-33/ST-2/NFκB SIGNALING ON MAST CELL-INDUCED PRIMARY SCLEROSING CHOLANGITIS (PSC)
Li-Xian Chen, L. Pham, L. Kennedy, Wenjun Zhang +9 more
20210 citations
Semantic Scholar
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSC
M. Awoniyi, Jeremy R. Wang, Billy Ngo, Vik Meadows +17 more
2021bioRxiv0 citations Open access
Semantic Scholar
693 CROSSTALK SIGNALING BETWEEN MAST CELLS, HISTAMINE AND STIMULATOR OF INTERFERON GENE (STING/TMEM173) PROMOTES CHOLANGIOCARCINOMA (CCA) TUMORIGENESIS
Konstantina Kyritsi, Tianhao Zhou, L. Kennedy, Vik Meadows +9 more
20200 citations
Semantic Scholar
319 TREATMENT WITH MELATONIN OR DARK THERAPY DECREASES MAST CELL (MC) ACTIVATION BY DOWNREGULATION OF MIR-200B-DEPENDENT HISTAMINE (HA) SIGNALING IN MDR2-/- MICE: A NOVEL SCENARIO FOR PSC MANAGEMENT
Li-Xian Chen, N. Wu, S. Glaser, Ludovica Ceci +8 more
20200 citations
Semantic Scholar
Sa1493 COORDINATED REGULATION OF SENSORY INNERVATION AND MAST CELL ACTIVATION CONTRIBUTES TO BILIARY DAMAGE AND HEPATIC FIBROSIS
Debjyoti Kundu, Vik Meadows, L. Kennedy, Ludovica Ceci +7 more
20200 citations
Semantic Scholar

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H. Francis×46
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H. Francis — researcher profile on SciRah
L. Kennedy×42
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L. Kennedy — researcher profile on SciRah
G. Alpini×41
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G. Alpini — researcher profile on SciRah
Konstantina Kyritsi×30
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Konstantina Kyritsi — researcher profile on SciRah

×29

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Debjyoti Kundu — researcher profile on SciRah

Tianhao Zhou×27

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Tianhao Zhou — researcher profile on SciRah

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S. Glaser — researcher profile on SciRah

Ludovica Ceci×24

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Ludovica Ceci — researcher profile on SciRah

Li-Xian Chen×21

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Li-Xian Chen — researcher profile on SciRah

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N. Wu — researcher profile on SciRah

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B. Ekser — researcher profile on SciRah

L. Baiocchi×11

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L. Baiocchi — researcher profile on SciRah