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Karol Szczepanek · SciRah

Researcher profile · Semantic Scholar

Karol Szczepanek

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Karol Szczepanek — researcher profile on SciRah

h-index: 19
Works: 40
Citations: 2,393

Most-cited papers

Function of Mitochondrial Stat3 in Cellular Respiration
J. Węgrzyn, Ramesh Potla, Y. Chwae, N. B. Sepuri +22 more
2009Science1,033 citations Open access
Semantic Scholar
Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species*
Karol Szczepanek, Qun Chen, Marta Derecka, Fadi N. Salloum +7 more
2011Journal of Biological Chemistry226 citations Open access
Semantic Scholar
Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727*
Qi-Fang Zhang, V. Raje, V. Yakovlev, A. Yacoub +11 more
2013Journal of Biological Chemistry181 citations Open access
Semantic Scholar
Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy due to Pulmonary Arterial Hypertension
J. Gómez-Arroyo, S. Mizuno, Karol Szczepanek, B. Van Tassell +12 more
2012Circulation: Heart Failure167 citations Open access
Semantic Scholar
Cytoprotection by the Modulation of Mitochondrial Electron Transport Chain: The Emerging Role of Mitochondrial STAT3
Karol Szczepanek, Qun Chen, A. Larner, E. Lesnefsky
2011Mitochondrion (Amsterdam. Print)121 citations Open access
Semantic Scholar
Multi-Tasking: Nuclear Transcription Factors with Novel Roles in the Mitochondria
Karol Szczepanek, E. Lesnefsky, A. Larner
2012Trends in Cell Biology111 citations Open access
Semantic Scholar
Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity
Marta Derecka, A. Górnicka, Sergei B Koralov, Karol Szczepanek +20 more
2012Cell Metabolism98 citations Open access
Semantic Scholar
Integrated analyses of murine breast cancer models reveal critical parallels with human disease
J. Rennhack, B. To, Matthew R. Swiatnicki, Caleb Dulak +11 more
2019Nature Communications54 citations Open access
Semantic Scholar
Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury
Karol Szczepanek, Ai-Jun Xu, Ying Hu, Jeremy Thompson +5 more
2015Basic Research in Cardiology45 citations
Semantic Scholar
Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury.
Ai-Jun Xu, Karol Szczepanek, Michael Maceyka, Thomas Ross +8 more
2014American Journal of Physiology - Cell Physiology45 citations Open access
Semantic Scholar
The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes
J. Sisler, Magdalena Morgan, V. Raje, Rebecca C. Grande +9 more
2015PLoS ONE40 citations Open access
Semantic Scholar
Electron flow into cytochrome c coupled with reactive oxygen species from the electron transport chain converts cytochrome c to a cardiolipin peroxidase: role during ischemia-reperfusion
Hema S. Aluri, D. Simpson, J. Allegood, Ying Hu +4 more
2014Biochimica et Biophysica Acta38 citations Open access
Semantic Scholar
Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: Role of complex I inhibition vs. depolarization of inner mitochondrial membrane
Thomas Ross, Karol Szczepanek, E. Bowler, Ying Hu +3 more
2013Biochimica et Biophysica Acta37 citations Open access
Semantic Scholar
Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia.
G. Collet, K. Szade, W. Nowak, Krzysztof Klimkiewicz +16 more
2016Cancer Letters31 citations Open access
Semantic Scholar
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations
Melissa A. Pegues, Karol Szczepanek, Faruk G. Sheikh, Seth G Thacker +6 more
2021Pharmaceutical Research24 citations Open access
Semantic Scholar
Cardioprotection by modulation of mitochondrial respiration during ischemia-reperfusion: role of apoptosis-inducing factor.
Ai-Jun Xu, Karol Szczepanek, Ying Hu, E. Lesnefsky +1 more
2013Biochemical and Biophysical Research Communications - BBRC23 citations
Semantic Scholar
The genomic landscape of metastasis in treatment-naïve breast cancer models
Christina Ross, Karol Szczepanek, Maxwell P. Lee, H. Yang +3 more
2019bioRxiv21 citations Open access
Semantic Scholar
The Role of Tyk2 in Regulation of Breast Cancer Growth
Qi-Fang Zhang, J. Sturgill, Maciej Kmieciak, Karol Szczepanek +13 more
2011Journal of Interferon and Cytokine Research20 citations Open access
Semantic Scholar
Differential binding of hyaluronan on the surface of tissue-specific endothelial cell lines.
Karol Szczepanek, C. Kieda, J. Cichy
2008Acta Biochimica Polonica20 citations Open access
Semantic Scholar
Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury.
Karol Szczepanek, J. Allegood, Hema S. Aluri, Ying Hu +2 more
2016Biochimica et Biophysica Acta17 citations
Semantic Scholar
Metastasis-specific gene expression in autochthonous and allograft mouse mammary tumor models: stratification and identification of targetable signatures.
Christina Ross, Karol Szczepanek, Maxwell P. Lee, H. Yang +7 more
2019Molecular Cancer Research14 citations Open access
Semantic Scholar
A deficiency of apoptosis inducing factor (AIF) in Harlequin mouse heart mitochondria paradoxically reduces ROS generation during ischemia-reperfusion
Qun Chen, Karol Szczepanek, Ying Hu, Jeremy Thompson +1 more
2014Frontiers in Physiology14 citations Open access
Semantic Scholar
Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells
V. Raje, Marta Derecka, Marc T. Cantwell, Jeremy A. Meier +6 more
2016Endocrinology11 citations Open access
Semantic Scholar
Targeting metastatic breast cancer: problems and potential
Sarah K. Deasy, Karol Szczepanek, K. Hunter
2015F1000 faculty reviews4 citations Open access
Semantic Scholar
Deficiency of Apoptosis Inducing Factor (AIF) decreases complex I activity and increases the ROS generation in isolated cardiac mitochondria
Karol Szczepanek, Ying Hu, E. Lesnefsky, Qun Chen
20133 citations
Semantic Scholar
Integrated sequence and gene expression analysis of mouse models of breast cancer reveals critical events with human parallels
J. Rennhack, Matthew R. Swiatnicki, Yueqi Zhang, Caralynn Li +7 more
2018bioRxiv2 citations Open access
Semantic Scholar
247 : Stat1 inhibits mitochondrial biogenesis
J. Sisler, M. Szeląg, V. Raje, Marta Derecka +3 more
20131 citations
Semantic Scholar
Metabolic Remodeling In Right Ventricular Failure Is Associated With Abnormal Mitochondrial Biogenesis
J. Gómez-Arroyo, Karol Szczepanek, A. Syed, L. Farkas +6 more
2012Asian Test Symposium1 citations
Semantic Scholar
372 A novel function of STAT3 in cellular respiration
J. Węgrzyn, Ramesh Potla, Y. Chwae, Qi-Fang Zhang +10 more
20081 citations
Semantic Scholar
Abstract B28: Identification of breast cancer metastasis promoting genes by next generation sequencing
Karol Szczepanek, K. Hunter
20160 citations
Semantic Scholar
Absence of microRNA-155 augments cardiac injury during ischemia–reperfusion
Karol Szczepanek, Jeremy Thompson, Ying Hu, Ai-Jun Xu +3 more
20150 citations
Semantic Scholar
Impaired tafazzin‐mediated remodeling of cardiolipin does not enhance susceptibility to ischemia and reperfusion injury (960.1)
Karol Szczepanek, J. Allegood, Hema S. Aluri, Ying Hu +2 more
20140 citations
Semantic Scholar
Abstract 18290: Mitochondrial-Targeted Overexpression of Transcriptionally Inactive STAT3 in the Heart Reduces Infarct Size and Improves Contractile Recovery Following Ischemia and Reperfusion
Karol Szczepanek, Ai-Jun Xu, Ying Hu, Qun Chen +1 more
2013Circulation0 citations
Semantic Scholar
Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right
E. Lesnefsky, H. Bogaard, N. Voelkel, Kraskauskas +13 more
20130 citations
Semantic Scholar
The JAK kinase Tyk2 and the Signal Transducer and Activator of Transcription 3 (Stat3) are required for Brown Adipose Tissue Differentiation
A. Larner, Marta Derecka, A. Górnicka, Karol Szczepanek +4 more
20120 citations
Semantic Scholar
Partial inhibition of complex I does not prevent reverse flow-induced ROS generation
Thomas Ross, Karol Szczepanek, Ying Hu, Qun Chen +1 more
20120 citations
Semantic Scholar
Blockade of electron transport before ischemia provides an additive protection in bcl-2 overexpressor mice following prolonged ischemia–reperfusion
Ai-Jun Xu, Karol Szczepanek, Ying Hu, Qun Chen +1 more
20120 citations
Semantic Scholar
Mitochondrial overexpression of transcriptionally inactive STAT3 in the heart prtects respiratory complex I against ischemia-induced damage
Karol Szczepanek
20100 citations
Semantic Scholar
The role of Stat1 in regulation of mitochondrial gene expression
J. Sisler, M. Szeląg, Ramesh Potla, Qi-Fang Zhang +12 more
20100 citations
Semantic Scholar
VCU Scholars Compass VCU Scholars Compass
J. Sisler, Magdalena Morgan, V. Raje, Rebecca C. Grande +9 more
0 citations
Semantic Scholar

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