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K. Bzymek · SciRah

Researcher profile · Semantic Scholar

K. Bzymek

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K. Bzymek — researcher profile on SciRah

h-index: 15
Works: 63
Citations: 662

Most-cited papers

Biochemistry of the Initial Steps of Mycothiol Biosynthesis*
G. Newton, P. Ta, K. Bzymek, R. C. Fahey
2006Journal of Biological Chemistry76 citations Open access
Semantic Scholar
Co-catalytic metallopeptidases as pharmaceutical targets.
R. Holz, K. Bzymek, S. Swierczek
2003Current Opinion in Chemical Biology62 citations
Semantic Scholar
The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition.
W. Desmarais, David Bienvenue, K. Bzymek, R. Holz +2 more
2002Structure57 citations Open access
Semantic Scholar
Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies
J. Donaldson, C. Zer, K. Avery, K. Bzymek +2 more
2013Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Two translation products of Yersinia yscQ assemble to form a complex essential to type III secretion
K. Bzymek, B. Hamaoka, P. Ghosh
2012Biochemistry51 citations Open access
Semantic Scholar
The Catalytic Role of Glutamate 151 in the Leucine Aminopeptidase from Aeromonas proteolytica*
K. Bzymek, R. Holz
2004Journal of Biological Chemistry51 citations Open access
Semantic Scholar
The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus
F. Hillmann, K. Bagramyan, M. Straßburger, T. Heinekamp +5 more
2016Scientific Reports37 citations Open access
Semantic Scholar
Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design
T. Riley, H. Chou, R.-T. Hu, K. Bzymek +8 more
2021Frontiers in Immunology34 citations Open access
Semantic Scholar
The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica
W. Desmarais, David Bienvenue, K. Bzymek, G. Petsko +2 more
2006JBIC Journal of Biological Inorganic Chemistry32 citations Open access
Semantic Scholar
Mycothiol Import by Mycobacterium smegmatis and Function as a Resource for Metabolic Precursors and Energy Production
K. Bzymek, G. Newton, P. Ta, R. C. Fahey
2007Journal of Bacteriology28 citations Open access
Semantic Scholar
Role of α-Asp181, β-Asp192, and γ-Asp190 in the Distinctive Subunits of Human NAD-Specific Isocitrate Dehydrogenase†
K. Bzymek, R. Colman
200725 citations
Semantic Scholar
RWD Domain as an E2 (Ubc9)-Interaction Module*
A. Alontaga, Nigus D. Ambaye, Yi-Jia Li, R. Vega +5 more
2015Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica.
K. Bzymek, Ventris M. D'Souza, Guan-Jin Chen, Heidi J. Campbell +2 more
2004Protein Expression and Purification19 citations
Semantic Scholar
Rational selection of building blocks for the assembly of bispecific antibodies
D. Gong, T. Riley, K. Bzymek, A. R. Correia +6 more
2021mAbs17 citations Open access
Semantic Scholar
Mechanically interlocked functionalization of monoclonal antibodies
K. Bzymek, James W. Puckett, C. Zer, Jun Xie +8 more
2018Nature Communications15 citations Open access
Semantic Scholar
Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica.
K. Bzymek, A. Moulin, S. Swierczek, D. Ringe +3 more
2005Biochemistry15 citations
Semantic Scholar
Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica.
K. Bzymek, S. Swierczek, B. Bennett, R. Holz
2005Inorganic Chemistry11 citations
Semantic Scholar
Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A
C. Zer, K. Avery, Kassondra Meyer, Leah H Goodstein +3 more
2017Protein engineering, design & selection : PEDS9 citations Open access
Semantic Scholar
Development of a High Affinity, Non-covalent Biologic to Add Functionality to Fabs
K. Avery, C. Zer, K. Bzymek, John C. Williams
2015Scientific Reports9 citations Open access
Semantic Scholar
Cyclization strategies of meditopes: affinity and diffraction studies of meditope–Fab complexes
K. Bzymek, Yue-Long Ma, Kendra A. Avery, D. Horne +1 more
2016Acta Crystallographica Section F Structural Biology Communications8 citations Open access
Semantic Scholar
Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase.
K. Bzymek, R. Colman
2007Biochemistry8 citations
Semantic Scholar
Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
Jeremy D. King, Yue-Long Ma, Yi-Chui Kuo, K. Bzymek +8 more
2018Bioconjugate chemistry7 citations Open access
Semantic Scholar
Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope–Fab complexes
K. Bzymek, Kendra A. Avery, Yue-Long Ma, D. Horne +1 more
2016Acta Crystallographica Section F Structural Biology Communications6 citations Open access
Semantic Scholar
Meditope–Fab interaction: threading the hole
K. Bzymek, Yue-Long Ma, K. Avery, D. Horne +1 more
2017Acta Crystallographica Section F Structural Biology Communications3 citations Open access
Semantic Scholar
Observation of an E2 (Ubc9)-homodimer by crystallography
A. Alontaga, Nigus D. Ambaye, Yi-Jia Li, R. Vega +5 more
2016Data in Brief3 citations Open access
Semantic Scholar
Structure of rituximab Fab
K. Bzymek, J. Williams
20142 citations
Semantic Scholar
Kinetic, Spectroscopic, and X-ray Crystallographic Characterization of the Functional E151H Aminopeptidase from <em>Aeromonas proteolytica</em>
K. Bzymek, A. Moulin, S. Swierczek
20200 citations
Semantic Scholar
MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT IN COMPLEX WITH (Ac) CQFDA(PH)2STRRLRCGGSK
K. Bzymek, K. Avery, C. Zer, John C. Williams
20180 citations
Semantic Scholar
Trastuzumab Fab v3 in complex with CQFDLSTRRLKC
K. Bzymek, J. D. King, J. Williams
20180 citations
Semantic Scholar
STRUCTURE OF MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT
K. Bzymek, K. Avery, C. Zer, John C. Williams
20180 citations
Semantic Scholar
Trastuzumab Fab v3 with 5-diphenyl meditope variant
K. Bzymek, J. D. King, J. Williams
20180 citations
Semantic Scholar
Trastuzumab Fab v3 in complex with 5-phenyl meditope variant
K. Bzymek, J. D. King, J. Williams
20180 citations
Semantic Scholar
Structure of cetuximab with aminoheptanoic acid-linked N-(3-hydroxypropyl)-L-arginine meditope variant
K. Bzymek, J. Williams
20170 citations
Semantic Scholar
Structure of cetuximab with aminoheptanoic acid-linked N-carboxyethylarginine meditope variant
K. Bzymek, J. Williams
20170 citations
Semantic Scholar
Cetuximab Fab in complex with Arg8Cir meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with aminoheptanoic acid-linked meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Crystal structure of peroxiredoxin Asp f3
K. Bzymek, John C. Williams, T. Hong, K. Bagramyan +1 more
20160 citations
Semantic Scholar
Cetuximab Fab in complex with 3-bromophenylalanine meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with CQYDLSTRRLKC
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with CQFDLSTRRLRCGGSK meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with cyclic beta-alanine-linked meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with amidated meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with linear meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with L5Y meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with CQA(Ph)2DLSTRRLKC peptide
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with CQFDA(Ph)2STRRLKC
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Structure of cetuximab Fab with cyclic F3Q variant of the meditope
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with 4-bromophenylalanine meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with L10Q meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar
Cetuximab Fab in complex with F3H meditope variant
K. Bzymek, J. Williams
20160 citations
Semantic Scholar

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