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T. Mace · SciRah

Researcher profile · Semantic Scholar

T. Mace

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T. Mace — researcher profile on SciRah

h-index: 34
Works: 94
Citations: 3,811

Most-cited papers

IL-6 and PD-L1 antibody blockade combination therapy reduces tumor progression in murine models of pancreatic cancer
T. Mace, Reena Shakya, Jason R. Pitarresi, Benjamin J. Swanson +13 more
2016Gut473 citations Open access
Semantic Scholar
Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
T. Mace, Zeenath Ameen, Amy L. Collins, Sylwia E. Wojcik +8 more
2013Cancer Research383 citations Open access
Semantic Scholar
Nitric Oxide Production by Myeloid Derived Suppressor Cells Plays a Role in Impairing Fc Receptor-Mediated Natural Killer Cell Function.
Andrew Stiff, P. Trikha, Bethany L. Mundy-Bosse, Elizabeth L. McMichael +20 more
2018Clinical Cancer Research206 citations Open access
Semantic Scholar
Myeloid-derived suppressor cells express Bruton’s tyrosine kinase and can be depleted in tumor bearing hosts by ibrutinib treatment
Andrew Stiff, P. Trikha, R. Wesolowski, K. Kendra +20 more
2016Cancer Research176 citations Open access
Semantic Scholar
Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma.
A. Noonan, M. Farren, S. Geyer, Ying Huang +16 more
2016Molecular Therapy161 citations Open access
Semantic Scholar
Generation of monocyte-derived tumor-associated macrophages using tumor-conditioned media provides a novel method to study tumor-associated macrophages in vitro
B. Benner, Luke Scarberry, L. Suarez-Kelly, M. Duggan +10 more
2019Journal of Immunotherapy for Cancer149 citations Open access
Semantic Scholar
Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
S. B. Gomez-Chou, A. Świdnicka-Siergiejko, Niharika Badi, M. Chavez-Tomar +16 more
2017Cancer Research135 citations Open access
Semantic Scholar
Differentiation of CD8+ T cells into effector cells is enhanced by physiological range hyperthermia
T. Mace, Ling-Wen Zhong, C. Kilpatrick, E. Zynda +4 more
2011Journal of Leukocyte Biology107 citations Open access
Semantic Scholar
Effector CD8+ T cell IFN-γ production and cytotoxicity are enhanced by mild hyperthermia
T. Mace, Ling-Wen Zhong, Kathleen M Kokolus, E. Repasky
2012International Journal of Hyperthermia102 citations Open access
Semantic Scholar
Hypoxia-Driven Immunosuppression: A new reason to use thermal therapy in the treatment of cancer?
Chen-Ting Lee, T. Mace, E. Repasky
2010International Journal of Hyperthermia91 citations Open access
Semantic Scholar
Hypoxia induces the overexpression of MicroRNA-21 in pancreatic cancer cells
T. Mace, Amy L. Collins, Sylwia E. Wojcik, C. Croce +2 more
2013Journal of Surgical Research87 citations Open access
Semantic Scholar
CD200 promotes immunosuppression in the pancreatic tumor microenvironment
F. Choueiry, Molly A. Torok, Reena Shakya, Kriti Agrawal +14 more
2020Journal for ImmunoTherapy of Cancer86 citations Open access
Semantic Scholar
Systemic immune activity predicts overall survival in treatment naïve patients with metastatic pancreatic cancer
M. Farren, T. Mace, S. Geyer, S. Mikhail +8 more
2015Clinical Cancer Research84 citations Open access
Semantic Scholar
Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines
Matthew A. Bill, C. Nicholas, T. Mace, Jonathan P. Etter +10 more
2012PLoS ONE84 citations Open access
Semantic Scholar
Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo
Hannah M. Komar, Gregory L. Serpa, Claire Kerscher, Erin Schwoegl +9 more
2017Scientific Reports83 citations Open access
Semantic Scholar
Elevation in Body Temperature to Fever Range Enhances and Prolongs Subsequent Responsiveness of Macrophages to Endotoxin Challenge
Chen-Ting Lee, Ling-Wen Zhong, T. Mace, E. Repasky
2012PLoS ONE82 citations Open access
Semantic Scholar
Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced pro-inflammatory cytokines and immune suppressive cells
G. Lesinski, P. Reville, T. Mace, G. Young +8 more
2015Cancer Prevention Research77 citations Open access
Semantic Scholar
Circulating myeloid derived suppressor cells increase in patients undergoing neo-adjuvant chemotherapy for breast cancer
R. Wesolowski, M. Duggan, Andrew Stiff, J. Markowitz +14 more
2017Cancer Immunology and Immunotherapy70 citations Open access
Semantic Scholar
A Phase 1 Trial of Single Agent Reolysin in Patients with Relapsed Multiple Myeloma
D. Sborov, G. Nuovo, Andrew Stiff, T. Mace +7 more
2014Clinical Cancer Research70 citations Open access
Semantic Scholar
Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function
T. Mace, M. Ware, Samantha A. King, S. Loftus +8 more
2019Scientific Reports61 citations Open access
Semantic Scholar
Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.
M. Capitano, Michael J. Nemeth, T. Mace, Christi T Salisbury-Ruf +3 more
2012Blood48 citations Open access
Semantic Scholar
Bioactive compounds or metabolites from black raspberries modulate T lymphocyte proliferation, myeloid cell differentiation and Jak/STAT signaling
T. Mace, Samantha A. King, Zeenath Ameen, O. Elnaggar +7 more
2014Cancer Immunology and Immunotherapy47 citations Open access
Semantic Scholar
Serum Albumin: Early Prognostic Marker of Benefit for Immune Checkpoint Inhibitor Monotherapy But Not Chemoimmunotherapy
Yi-Zhen Guo, Lai Wei, Sandip H. Patel, G. Lopez +18 more
2022Clinical Lung Cancer46 citations Open access
Semantic Scholar
Pancreatic cancer-associated stellate cells
T. Mace, M. Bloomston, G. Lesinski
2013Oncoimmunology44 citations Open access
Semantic Scholar
Regulation of Cellular Immunity by Activating Transcription Factor 4
Debasmita Mukherjee, Lena Bercz, Molly A. Torok, T. Mace
2020Immunology Letters43 citations Open access
Semantic Scholar
Circulating Interleukin-6 is Associated with Disease Progression, but not Cachexia in Pancreatic Cancer
M. Ramsey, E. Talbert, D. Ahn, T. Bekaii-Saab +17 more
2018Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]43 citations Open access
Semantic Scholar
Pancreatic Cancer-Induced Cachexia and Relevant Mouse Models
Sally E. Henderson, Neil Makhijani, T. Mace
2018Pancreas42 citations Open access
Semantic Scholar
Dietary α-mangostin, a xanthone from mangosteen fruit, exacerbates experimental colitis and promotes dysbiosis in mice
F. Gutierrez-orozco, J. Thomas-Ahner, Lisa D. Berman-Booty, J. Galley +7 more
2014Molecular Nutrition & Food Research42 citations Open access
Semantic Scholar
Ultraviolet Light B-Mediated Inhibition of Skin Catalase Activity Promotes Gr-1+CD11b+ Myeloid Cell Expansion
Nicholas J. Sullivan, K. Tober, E. M. Burns, Jonathan S. Schick +6 more
2011Journal of Investigative Dermatology41 citations Open access
Semantic Scholar
Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression
Debasmita Mukherjee, S. Chakraborty, Lena Bercz, L. D'Alesio +15 more
2023iScience37 citations Open access
Semantic Scholar
An IL-15-based super agonist ALT-803 enhances the NK cell response to cetuximab-treated squamous cell carcinoma of the head and neck
Ashley Pinette, Elizabeth L. McMichael, Nicholas B. Courtney, M. Duggan +6 more
2019Cancer Immunology and Immunotherapy36 citations Open access
Semantic Scholar
Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia
Jason R. Pitarresi, Xin Liu, Sudarshana M. Sharma, M. Cuitiño +20 more
2016Neoplasia35 citations Open access
Semantic Scholar
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner
M. Ware, M. Phillips, Christopher W McQuinn, Mohammad Y. Zaidi +17 more
2023JCI Insight34 citations Open access
Semantic Scholar
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth
Jason R. Pitarresi, Xin Liu, Alex Avendano, K. Thies +28 more
2018Life Science Alliance34 citations Open access
Semantic Scholar
A Multi-Center, Single Arm, Phase Ib study of Pembrolizumab (MK-3475) in Combination with Chemotherapy for Patients with Advanced Colorectal Cancer: HCRN GI14-186
C. Herting, M. Farren, Y. Tong, Zi-Yue Liu +10 more
2021Cancer Immunology and Immunotherapy33 citations Open access
Semantic Scholar
Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through Both Tumor Extrinsic and Intrinsic Activities
E. Talbert, Jennifer Yang, T. Mace, M. Farren +11 more
2016Molecular Cancer Therapeutics32 citations Open access
Semantic Scholar
The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells
S. M. D. del Campo, Kala M. Levine, Bethany L. Mundy-Bosse, V. Grignol +21 more
2015Journal of Immunology32 citations Open access
Semantic Scholar
A role for the thermal environment in defining co-stimulation requirements for CD4+ T cell activation
E. Zynda, Melissa J. Grimm, Min Yuan, Ling-Wen Zhong +6 more
2015Cell Cycle30 citations Open access
Semantic Scholar
Nucleoside transporters and immunosuppressive adenosine signaling in the tumor microenvironment: Potential therapeutic opportunities
T. Kaur, Brenna Weadick, T. Mace, Kajal Desai +2 more
2022Pharmacology and Therapeutics28 citations Open access
Semantic Scholar
Lipocalin-2 Expression and Function in Pancreatic Diseases
Kristyn Gumpper, Andrew W. Dangel, Valentina Pita-Grisanti, S. Krishna +6 more
2020Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]26 citations Open access
Semantic Scholar
β-Sitosterol modulates TLR4 receptor expression and intracellular MyD88-dependent pathway activation in J774A.1 murine macrophages.
M. Valerio, H. Minderman, T. Mace, A. B. Awad
2013Cellular Immunology26 citations
Semantic Scholar
Murine cancer cachexia models replicate elevated catabolic pembrolizumab clearance in humans
A. Castillo, T. Vu, Sophia G. Liva, Min Chen +14 more
2021JCSM Rapid Communications20 citations Open access
Semantic Scholar
Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
W. Fisher, Z. Cruz-Monserrate, Amy L. McElhany, G. Lesinski +24 more
2018Pancreas20 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy
Steven H Sun, Colin D Angell, Himanshu Savardekar, D. Sundi +16 more
2023Cancer Immunology and Immunotherapy16 citations Open access
Semantic Scholar
The Potential of the Tumor Microenvironment to Influence Apo2L/TRAIL Induced Apoptosis
T. Mace, Nariyuke Yamane, Jinrong Cheng, B. Hylander +1 more
2006Immunological Investigations16 citations
Semantic Scholar
Exploratory analysis of immune checkpoint receptor expression by circulating T cells and tumor specimens in patients receiving neo-adjuvant chemotherapy for operable breast cancer
R. Wesolowski, Andrew Stiff, Dionisia Quiroga, Christopher W McQuinn +18 more
2020BMC Cancer15 citations Open access
Semantic Scholar
Pancreatic cancer stem cells in patient pancreatic xenografts are sensitive to drozitumab, an agonistic antibody against DR5
J. Eng, T. Mace, Rohit Sharma, Danielle Y. F. Twum +7 more
2016Journal of Immunotherapy for Cancer14 citations Open access
Semantic Scholar
Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancer
T. Mace, Reena Shakya, O. Elnaggar, K. Wilson +9 more
2015OncoTarget14 citations Open access
Semantic Scholar
A Phase I Study of High-Dose Interleukin-2 With Sorafenib in Patients With Metastatic Renal Cell Carcinoma and Melanoma
P. Monk, E. Lam, A. Mortazavi, K. Kendra +8 more
2014Journal of immunotherapy13 citations Open access
Semantic Scholar

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