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I. Vlodavsky · SciRah

Researcher profile · Semantic Scholar

I. Vlodavsky

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I. Vlodavsky — researcher profile on SciRah

h-index: 104
Works: 553
Citations: 34K

Most-cited papers

Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior
S. Bandari, A. Purushothaman, V. Ramani, Garrett J. Brinkley +7 more
2017Matrix Biology211 citations Open access
Semantic Scholar
The Potential of Low Molecular Weight Heparin to Mitigate Cytokine Storm in Severe COVID‐19 Patients: A Retrospective Cohort Study
Chen Shi, Cong Wang, Han-Xiang Wang, Chao Yang +9 more
2020Clinical and Translational Science201 citations Open access
Semantic Scholar
Parabacteroides produces acetate to alleviate heparanase-exacerbated acute pancreatitis through reducing neutrophil infiltration
Yuan-Yuan Lei, Li Tang, Shuang Liu, Shi-Ping Hu +11 more
2021Microbiome184 citations Open access
Semantic Scholar
Proteases and glycosidases on the surface of exosomes: Newly discovered mechanisms for extracellular remodeling
R. Sanderson, S. Bandari, I. Vlodavsky
2017Matrix Biology162 citations Open access
Semantic Scholar
Opposing functions of heparanase-1 and heparanase-2 in cancer progression
I. Vlodavsky, Miriam Gross-Cohen, Marina Weissmann, N. Ilan +1 more
2017TIBS -Trends in Biochemical Sciences. Regular ed123 citations Open access
Semantic Scholar
Extracellular matrix-based cancer targeting.
Nikos Karamanos, Z. Piperigkou, A. Passi, M. Götte +2 more
2021Trends in Molecular Medicine112 citations Open access
Semantic Scholar
Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds
C. D. Mohan, Swetha Hari, Habbanakuppe D. Preetham, S. Rangappa +7 more
2019iScience91 citations Open access
Semantic Scholar
Heparanase-enhanced Shedding of Syndecan-1 and Its Role in Driving Disease Pathogenesis and Progression
Sunil Rangarajan, J. R. Richter, R. Richter, S. Bandari +3 more
2020Journal of Histochemistry and Cytochemistry75 citations Open access
Semantic Scholar
COVID‐19‐induced endotheliitis: emerging evidence and possible therapeutic strategies
E. Calabretta, J. Moraleda, M. Iacobelli, R. Jara +11 more
2021British Journal of Haematology71 citations Open access
Semantic Scholar
Forty Years of Basic and Translational Heparanase Research
I. Vlodavsky, N. Ilan, R. Sanderson
2020Advances in Experimental Medicine and Biology50 citations Open access
Semantic Scholar
The heparanase inhibitor PG545 is a potent anti-lymphoma drug: Mode of action.
Marina Weissmann, U. Bhattacharya, S. Feld, E. Hammond +2 more
2019Matrix Biology47 citations
Semantic Scholar
Specific Inhibition of Heparanase by Glycopolymer with Well-Defined Sulfation Pattern Prevents Breast Cancer Metastasis in Mice
Ravi S. Loka, E. Sletten, Uri Barash, I. Vlodavsky +1 more
2018ACS Applied Materials and Interfaces47 citations Open access
Semantic Scholar
Involvement of Heparanase in the Pathogenesis of Mesothelioma: Basic Aspects and Clinical Applications
Uri Barash, M. Lapidot, Y. Zohar, C. Loomis +11 more
2018Journal of the National Cancer Institute46 citations Open access
Semantic Scholar
Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity
C. Baburajeev, C. D. Mohan, S. Rangappa, Daniel J. Mason +6 more
2017BMC Cancer45 citations Open access
Semantic Scholar
Involvement of heparanase in the pathogenesis of acute kidney injury: nephroprotective effect of PG545
Z. Abassi, S. Hamoud, Ahmad Hassan, I. Khamaysi +13 more
2017OncoTarget42 citations Open access
Semantic Scholar
Clinical observations of low molecular weight heparin in relieving inflammation in COVID-19 patients: A retrospective cohort study
Chen Shi, Cong Wang, Han-Xiang Wang, Chao Yang +9 more
2020medRxiv40 citations Open access
Semantic Scholar
Helicobacter pylori-Induced Heparanase Promotes H. pylori Colonization and Gastritis
Li Tang, Bo Tang, Yuan-Yuan Lei, Min Yang +6 more
2021Frontiers in Immunology39 citations Open access
Semantic Scholar
Biology of the Heparanase–Heparan Sulfate Axis and Its Role in Disease Pathogenesis
I. Vlodavsky, Uri Barash, Hien M. Nguyen, Shi-Ming Yang +1 more
2021Seminars in Thrombosis and Hemostasis39 citations Open access
Semantic Scholar
The Role of Heparanase in the Pathogenesis of Acute Pancreatitis: A Potential Therapeutic Target
I. Khamaysi, Preeti Singh, S. Nasser, H. Awad +9 more
2017Scientific Reports39 citations Open access
Semantic Scholar
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo
C. de Boer, Z. Armstrong, Vincent A. J. Lit, Uri Barash +14 more
2022Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Heparanase promotes glioma progression via enhancing CD24 expression
Uri Barash, A. Spyrou, Pei Liu, Euvgeni Vlodavsky +7 more
2019International Journal of Cancer37 citations Open access
Semantic Scholar
Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.
Nathaniel Lal, Amy P Chiu, Fu-Long Wang, Da-Hai Zhang +5 more
2017American Journal of Physiology. Heart and Circulatory Physiology37 citations
Semantic Scholar
Heparanase expression upregulates platelet adhesion activity and thrombogenicity
H. Cui, Ying-xia Tan, C. Österholm, Xiao Zhang +3 more
2016OncoTarget37 citations Open access
Semantic Scholar
Heparanase and chemotherapy synergize to drive macrophage activation and enhance tumor growth
U. Bhattacharya, Lilach Gutter-Kapon, T. Kan, I. Boyango +8 more
2019Cancer Research35 citations Open access
Semantic Scholar
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth
A. Spyrou, Soumi Kundu, Lulu Haseeb, Di Yu +6 more
2017Molecular Cancer Therapeutics34 citations
Semantic Scholar
Targeting heparanase to the mammary epithelium enhances mammary gland development and promotes tumor growth and metastasis.
I. Boyango, Uri Barash, L. Fux, I. Naroditsky +2 more
2017Matrix Biology33 citations
Semantic Scholar
Heparanase accelerates obesity-associated breast cancer progression.
E. Hermano, Rachel Goldberg, A. Rubinstein, Amir Sonnenblick +8 more
2019Cancer Research31 citations Open access
Semantic Scholar
Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy.
O. Zubkova, Yassir A. Ahmed, S. Guimond, Sophia-Louise Noble +7 more
2018ACS Chemical Biology29 citations Open access
Semantic Scholar
Supersulfated low-molecular weight heparin synergizes with IGF1R/IR inhibitor to suppress synovial sarcoma growth and metastases.
G. Cassinelli, Laura Dal Bo, E. Favini, D. Cominetti +10 more
2018Cancer Letters29 citations
Semantic Scholar
Heparanase—A single protein with multiple enzymatic and nonenzymatic functions
I. Vlodavsky, Yasmin Kayal, Maram Hilwi, Soaad Soboh +2 more
2023Proteoglycan Research28 citations Open access
Semantic Scholar
Syndecan-1 deficiency promotes tumor growth in a murine model of colitis-induced colon carcinoma
Adi Binder Gallimidi, G. Nussbaum, E. Hermano, Barak Weizman +4 more
2017PLoS ONE28 citations Open access
Semantic Scholar
Significance of host heparanase in promoting tumor growth and metastasis
Gan-Lin Zhang, Lilach Gutter-Kapon, N. Ilan, Tahira Batool +9 more
2020Matrix Biology27 citations Open access
Semantic Scholar
The Heparanase Inhibitor PG545 Attenuates Colon Cancer Initiation and Growth, Associating with Increased p21 Expression
Preeti Singh, A. Blatt, S. Feld, Y. Zohar +7 more
2017Neoplasia23 citations Open access
Semantic Scholar
New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis
Uri Barash, S. Rangappa, C. D. Mohan, Divakar Vishwanath +4 more
2021Cancers22 citations Open access
Semantic Scholar
Heparanase-The Message Comes in Different Flavors.
N. Ilan, U. Bhattacharya, Uri Barash, I. Boyango +3 more
2020Advances in Experimental Medicine and Biology20 citations
Semantic Scholar
Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression
Charlotte B. Jendresen, A. Digre, H. Cui, Xiao Zhang +3 more
2019Scientific Reports20 citations Open access
Semantic Scholar
Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease
Xiao Zhang, P. O'Callaghan, Hong-Lian Li, Ying-xia Tan +7 more
2021Acta Neuropathologica Communications19 citations Open access
Semantic Scholar
Identification of strong intron enhancer in the heparanase gene: effect of functional rs4693608 variant on HPSE enhancer activity in hematological and solid malignancies
O. Ostrovsky, A. H. Grushchenko-Polaq, Katia Beider, M. Mayorov +4 more
2018Oncogenesis19 citations Open access
Semantic Scholar
Prognostic significance of heparanase expression in primary and metastatic breast carcinoma
O. Vornicova, I. Naroditsky, I. Boyango, S. S. Shachar +4 more
2017OncoTarget19 citations Open access
Semantic Scholar
Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides
Sanyong Zhu, Jiayi Li, Ravi S. Loka, Zhenfeng Song +3 more
2020Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Syndecan-1-Dependent Regulation of Heparanase Affects Invasiveness, Stem Cell Properties, and Therapeutic Resistance of Caco2 Colon Cancer Cells
S. Katakam, Paride Pelucchi, Cinzia Cocola, R. Reinbold +3 more
2020Frontiers in Oncology18 citations Open access
Semantic Scholar
Is host heparanase required for the rapid spread of heparan sulfate binding viruses?
M. Khanna, C. Ranasinghe, Anna M. Browne, Jin-Ping Li +2 more
2019Virology18 citations Open access
Semantic Scholar
Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3
Ibrahim Knani, Preeti Singh, Miriam Gross-Cohen, S. Aviram +4 more
2021Matrix Biology17 citations Open access
Semantic Scholar
Heparanase 2 (Hpa2) attenuates tumor growth by inducing Sox2 expression.
Miriam Gross-Cohen, Yifat Yanku, Ofra Kessler, Uri Barash +5 more
2021Matrix Biology17 citations
Semantic Scholar
Heparanase 2 (Hpa2) attenuates the growth of pancreatic carcinoma.
Yasmin Kayal, Preeti Singh, I. Naroditsky, N. Ilan +1 more
2021Matrix Biology17 citations
Semantic Scholar
Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival
A. Agelidis, B. Turturice, R. Suryawanshi, Tejabhiram Yadavalli +15 more
2020bioRxiv16 citations Open access
Semantic Scholar
Heparanase protects the heart against chemical or ischemia/reperfusion injury.
Fu-Long Wang, T. Pulinilkunnil, S. Flibotte, C. Nislow +3 more
2019Journal of Molecular and Cellular Cardiology16 citations
Semantic Scholar
Overexpression of heparanase attenuated TGF‐β‐stimulated signaling in tumor cells
Tahira Batool, Jian-Ping Fang, Uri Barash, A. Moustakas +2 more
2017FEBS Open Bio16 citations Open access
Semantic Scholar
Heparin–Superparamagnetic Iron Oxide Nanoparticles for Theranostic Applications
Nicolò Massironi, M. Colombo, C. Cosentino, Luisa Fiandra +7 more
2022Molecules15 citations Open access
Semantic Scholar
Role of heparanase 2 (Hpa2) in gastric cancer
Jing-Jing Liu, Ibrahim Knani, Miriam Gross-Cohen, Jia-Xi Hu +5 more
2021Neoplasia15 citations Open access
Semantic Scholar

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N. Ilan×21
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N. Ilan — researcher profile on SciRah
Uri Barash×15
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Uri Barash — researcher profile on SciRah
Jin-Ping Li×11
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Jin-Ping Li — researcher profile on SciRah
R. Sanderson×9
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I. Boyango — researcher profile on SciRah

Miriam Gross-Cohen×6

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Miriam Gross-Cohen — researcher profile on SciRah

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E. Hammond — researcher profile on SciRah

Preeti Singh×5

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Preeti Singh — researcher profile on SciRah

Shi-Ming Yang×4

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S. Bandari — researcher profile on SciRah

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Li Tang — researcher profile on SciRah

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