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N. Hanssen · SciRah

Researcher profile · Semantic Scholar

N. Hanssen

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N. Hanssen — researcher profile on SciRah

h-index: 22
Works: 44
Citations: 1,862

Most-cited papers

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes
M. Kraakman, M. Lee, A. Al-sharea, D. Dragoljevic +17 more
2017Journal of Clinical Investigation196 citations Open access
Semantic Scholar
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype.
N. Hanssen, K. Wouters, M. Huijberts, M. Gijbels +10 more
2014European Heart Journal171 citations Open access
Semantic Scholar
Plasma Advanced Glycation End Products Are Associated With Incident Cardiovascular Events in Individuals With Type 2 Diabetes: A Case-Cohort Study With a Median Follow-up of 10 Years (EPIC-NL)
N. Hanssen, J. Beulens, S. van Dieren, J. Scheijen +5 more
2014Diabetes146 citations Open access
Semantic Scholar
Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study.
J. Scheijen, N. Hanssen, M. V. van Greevenbroek, C. V. D. van der Kallen +3 more
2017Clinical Nutrition134 citations Open access
Semantic Scholar
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis
Michelle C. Flynn, M. Kraakman, C. Tikellis, ManKS. Lee +22 more
2020Circulation Research117 citations Open access
Semantic Scholar
Plasma Levels of Advanced Glycation Endproducts and Pentosidine Are not Independently Associated With Cardiovascular Disease in Individuals With or Without Type 2 Diabetes: The Hoorn and CODAM Studies
N. Hanssen, L. Engelen, Isabel Ferreira, J. Scheijen +7 more
2013117 citations
Semantic Scholar
Small intestinal permeability is increased in diarrhoea predominant IBS, while alterations in gastroduodenal permeability in all IBS subtypes are largely attributable to confounders
Z. Mujagić, S. Ludidi, D. Keszthelyi, M. Hesselink +6 more
2014Alimentary Pharmacology and Therapeutics114 citations
Semantic Scholar
Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases
C. Teunis, M. Nieuwdorp, N. Hanssen
2022Metabolites105 citations Open access
Semantic Scholar
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes
N. Hanssen, J. Westerink, J. Scheijen, Y. van der Graaf +2 more
2018Diabetes Care89 citations Open access
Semantic Scholar
Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study
N. Hanssen, J. Scheijen, A. Jorsal, H. Parving +4 more
2017Diabetes75 citations Open access
Semantic Scholar
Post–Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study
D. E. Maessen, N. Hanssen, J. Scheijen, C. V. D. van der Kallen +3 more
2015Diabetes Care75 citations Open access
Semantic Scholar
Associations Between the Ankle-Brachial Index and Cardiovascular and All-Cause Mortality Are Similar in Individuals Without and With Type 2 Diabetes
N. Hanssen, M. Huijberts, C. Schalkwijk, G. Nijpels +2 more
2012Diabetes Care59 citations Open access
Semantic Scholar
Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids.
M. V. D. Van den Eynde, J. Geleijnse, J. Scheijen, N. Hanssen +5 more
2018Journal of NutriLife58 citations Open access
Semantic Scholar
The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1
M. V. van Eupen, M. Schram, H. Colhoun, N. Hanssen +6 more
2013Diabetologia55 citations Open access
Semantic Scholar
Methylglyoxal and glyoxalase I in atherosclerosis.
N. Hanssen, C. Stehouwer, C. Schalkwijk
2014Biochemical Society Transactions47 citations
Semantic Scholar
Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease
N. Hanssen, C. Stehouwer, C. Schalkwijk
2019Current opinion in nephrology and hypertension43 citations
Semantic Scholar
Energy restriction and Roux-en-Y gastric bypass reduce postprandial α-dicarbonyl stress in obese women with type 2 diabetes
D. E. Maessen, N. Hanssen, M. Lips, J. Scheijen +4 more
2016Diabetologia38 citations Open access
Semantic Scholar
Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial?
N. Hanssen, K. Jandeleit-Dahm
2019Diabetes & vascular disease research32 citations Open access
Semantic Scholar
Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE-/- mice with or without diabetes.
N. Hanssen, O. Brouwers, M. Gijbels, K. Wouters +7 more
2014Cardiovascular Research27 citations Open access
Semantic Scholar
Associations between presence of diabetes, mortality and fracture type in individuals with a hip fracture.
B. Spaetgens, S. Brouns, A. Linkens, M. Poeze +5 more
2022Diabetes Research and Clinical Practice23 citations Open access
Semantic Scholar
Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study.
N. Hanssen, J. Scheijen, A. Houben, M. V. D. van de Waarenburg +10 more
2020Diabetes & Metabolism23 citations Open access
Semantic Scholar
Residual β-Cell Function Is Associated With Longer Time in Range in Individuals With Type 1 Diabetes
Coco M. Fuhri Snethlage, T. Mcdonald, Richard A. Oram, Pleun de Groen +12 more
2023Diabetes Care22 citations Open access
Semantic Scholar
Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes.
N. Hanssen, M. Teraa, J. Scheijen, M. V. D. van de Waarenburg +4 more
2020Diabetes Care20 citations Open access
Semantic Scholar
Apoptotic ablation of platelets reduces atherosclerosis in mice with diabetes
M. Lee, M. Kraakman, D. Dragoljevic, N. Hanssen +12 more
2021Arteriosclerosis, Thrombosis and Vascular Biology16 citations Open access
Semantic Scholar
Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice.
N. Hanssen, C. Tikellis, R. Pickering, D. Dragoljevic +9 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie13 citations Open access
Semantic Scholar
Diet-induced weight loss reduces postprandial dicarbonyl stress in abdominally obese men: Secondary analysis of a randomized controlled trial.
M. V. D. Van den Eynde, Yvo H. A. M. Kusters, A. J. Houben, J. Scheijen +8 more
2021Clinical Nutrition13 citations Open access
Semantic Scholar
Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE).
M. V. D. Van den Eynde, L. Streese, A. J. Houben, C. Stehouwer +4 more
2020Clinical science11 citations Open access
Semantic Scholar
Recent advances in glucose-lowering treatment to reduce diabetic kidney disease
N. Hanssen, N. Russell, M. Cooper
2015Expert Opinion on Pharmacotherapy7 citations
Semantic Scholar
Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study
Kim Maasen, N. Hanssen, C. V. D. van der Kallen, C. Stehouwer +2 more
2021Antioxidants6 citations Open access
Semantic Scholar
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3‐deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub‐study
M. Piazza, N. Hanssen, F. Persson, J. Scheijen +7 more
2020Diabetic Medicine6 citations Open access
Semantic Scholar
Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies.
N. Hanssen, L. Engelen, Isabel Ferreira, J. Scheijen +7 more
2013Journal of Clinical Endocrinology and Metabolism4 citations Open access
Semantic Scholar
27-OR: Residual Beta-Cell Function Associates with Lower Glycaemic Variability and More Time in Range in Individuals with Type 1 Diabetes
Coco Fuhri Snethage, T. Mcdonald, E. Rampanelli, Pleun de Groen +7 more
2023Diabetes1 citations
Semantic Scholar
Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma
M. Piazza, N. Hanssen, J. Scheijen, M. Vd Waarenburg +5 more
2022Journal of Human Hypertension1 citations
Semantic Scholar
Is there a diminishing return of prior glycaemic control?
N. Hanssen, M. Cooper
2014The Lancet Diabetes and Endocrinology1 citations
Semantic Scholar
Plasma advanced glycation end products are not associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies
N. Hanssen, L. Engelen, Isabel Ferreira, J. Scheijen +7 more
20121 citations
Semantic Scholar
1313-P: The Prevalences of NAFLD and Liver Fibrosis Are High in Individuals with Type 1 Diabetes and Increase with Disease Progression
Coco Fuhri Snethage, A. Meijnikman, Pleun de Groen, Cengiz Callender +5 more
2023Diabetes0 citations
Semantic Scholar
ATORVASTATIN LOWERS 68GA-DOTATATE UPTAKE ACROSS THE CARDIO-HEMATOPOIETIC AXIS IN TYPE 2 DIABETES
R. Oostveen, Y. Kaiser, M. Ståhle, N. Nurmohamed +9 more
2023Journal of the American College of Cardiology0 citations Open access
Semantic Scholar
Abstract 232: Transient Intermittent Hyperglycemia Promotes Myelopoiesis and Accelerates Atherosclerosis in an S100A8/A9-RAGE Dependent Manner
Michelle C. Flynn, Michael Kraakman, ManKS. Lee, Christos Tikellis +9 more
2019Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Methylglyoxal, the glyoxalase pathway and advanced glycation endproducts in type 2 diabetes and cardiovasculair disease
N. Hanssen
20150 citations
Semantic Scholar
Abstract 698: Increases Reticulated Platelets due to Enhanced Proliferation and Expansion of Bone Marrow Megakaryocyte Progenitors Accelerates Atherosclerosis in Diabetes
M. Kraakman, D. Dragoljevic, N. Hanssen, K. Jandeleit-Dahm +8 more
20150 citations
Semantic Scholar
Response to Comment on: Hanssen et al. Associations Between the Ankle-Brachial Index and Cardiovascular and All-Cause Mortality Are Similar in Individuals Without and With Type 2 Diabetes: Nineteen-Year Follow-Up of a Population-Based Cohort Study. Diabetes Care 2012;35:1731–1735
N. Hanssen, M. Huijberts, C. Schalkwijk, G. Nijpels +2 more
2013Diabetes Care0 citations Open access
Semantic Scholar
PS1 - 1. Levels of Advanced Glycation Endproducts in carotid atherosclerotic plaques of individuals with and without diabetes correlate with characteristics of rupture-prone lesions
N. Hanssen, K. Wouters, M. Huijberts, M. Gijbels +9 more
2012Nederlands Tijdschrift voor Diabetologie0 citations
Semantic Scholar
PS3 - 18. Advanced glycation endproducts in atherosclerotic plaques: no further increase in patients with diabetes
N. Hanssen, C. Stehouwer, M. Huijberts, M. Brownlee +3 more
20110 citations
Semantic Scholar
Urinary D-lactate levels are increased in type 2 diabetic patients and are inversely associated with ankle arm index: The CODAM study
N. Hanssen, J. Scheijen, M. Huijberts, Isabel Ferreira +6 more
20100 citations
Semantic Scholar

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