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T. Shingaki · SciRah

Researcher profile · Semantic Scholar

T. Shingaki

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T. Shingaki — researcher profile on SciRah

h-index: 13
Works: 38
Citations: 633

Most-cited papers

Assessment of the First and Second Generation Antihistamines Brain Penetration and Role of P-Glycoprotein
T. Obradović, Glenn Dobson, T. Shingaki, Thomas Kungu +1 more
2007Pharmaceutical Research79 citations
Semantic Scholar
Transnasal delivery of methotrexate to brain tumors in rats: a new strategy for brain tumor chemotherapy.
T. Shingaki, Daisuke Inoue, Tomoyuki Furubayashi, Toshiyasu Sakane +3 more
2010Molecular Pharmaceutics72 citations
Semantic Scholar
Evaluation of Oatp and Mrp2 Activities in Hepatobiliary Excretion Using Newly Developed Positron Emission Tomography Tracer [11C]Dehydropravastatin in Rats
T. Shingaki, Tadayuki Takashima, Ryosuke Ijuin, Xuan Zhang +11 more
2013Journal of Pharmacology and Experimental Therapeutics52 citations
Semantic Scholar
Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse
T. Shingaki, W. Hume, Tadayuki Takashima, Yumiko Katayama +7 more
2015Pharmaceutical Research39 citations
Semantic Scholar
Imaging of Gastrointestinal Absorption and Biodistribution of an Orally Administered Probe Using Positron Emission Tomography in Humans
T. Shingaki, Tadayuki Takashima, Y. Wada, Masaaki Tanaka +6 more
2012Clinical pharmacology and therapy39 citations
Semantic Scholar
Visualization and Quantitative Assessment of the Brain Distribution of Insulin through Nose-to-Brain Delivery Based on the Cell-Penetrating Peptide Noncovalent Strategy.
N. Kamei, T. Shingaki, Yousuke Kanayama, Misa Tanaka +4 more
2016Molecular Pharmaceutics38 citations
Semantic Scholar
The synthesis and biodistribution of [(11)C]metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1) in vivo.
W. Hume, T. Shingaki, Tadayuki Takashima, Yoshinobu Hashizume +7 more
2013Bioorganic & Medicinal Chemistry37 citations Open access
Semantic Scholar
Efficacy and safety of once-weekly tirzepatide in Japanese patients with obesity disease (SURMOUNT-J): a multicentre, randomised, double-blind, placebo-controlled phase 3 trial.
T. Kadowaki, A. Kiyosue, T. Shingaki, Tomonori Oura +1 more
2025The Lancet Diabetes and Endocrinology35 citations
Semantic Scholar
Dynamic analysis of fluid distribution in the gastrointestinal tract in rats: positron emission tomography imaging after oral administration of nonabsorbable marker, [(18)F]Deoxyfluoropoly(ethylene glycol).
Tadayuki Takashima, T. Shingaki, Yumiko Katayama, Emi Hayashinaka +12 more
2013Molecular Pharmaceutics33 citations
Semantic Scholar
The transnasal delivery of 5-fluorouracil to the rat brain is enhanced by acetazolamide (the inhibitor of the secretion of cerebrospinal fluid).
T. Shingaki, I. Hidalgo, Tomoyuki Furubayashi, H. Katsumi +3 more
2009International journal of pharmaceutics30 citations
Semantic Scholar
In vitro evaluation of the ciliary beat frequency of the rat nasal epithelium using a high-speed digital imaging system.
Daisuke Inoue, Tomoyuki Furubayashi, K. Ogawara, Toshikiro Kimura +8 more
2013Biological and Pharmaceutical Bulletin24 citations Open access
Semantic Scholar
Nasal delivery of P-gp substrates to the brain through the nose-brain pathway.
T. Shingaki, I. Hidalgo, Tomoyuki Furubayashi, Toshiyasu Sakane +3 more
2011Drug Metabolism and Pharmacokinetics24 citations
Semantic Scholar
Dynamic Analysis of GI Absorption and Hepatic Distribution Processes of Telmisartan in Rats Using Positron Emission Tomography
M. Kataoka, Tadayuki Takashima, T. Shingaki, Yoshinobu Hashidzume +8 more
2012Pharmaceutical Research17 citations
Semantic Scholar
Efficacy and safety of subgroup analysis stratified by baseline HbA1c in a Japanese phase 3 study of dulaglutide 0.75 mg compared with insulin glargine in patients with type 2 diabetes.
Shizuka Kaneko, Tomonori Oura, A. Matsui, T. Shingaki +1 more
2017Endocrine journal13 citations Open access
Semantic Scholar
Transnasal delivery of anticancer drugs to the brain tumor : A new strategy for brain tumor chemotherapy
T. Shingaki, Toshiyasu Sakane, S. Yamashita, H. Sezaki +2 more
199913 citations Open access
Semantic Scholar
Key factors for overcoming psychological insulin resistance: A qualitative study in Japanese people with type 2 diabetes.
Kentaro Okazaki, Noriyuki Takahashi, T. Shingaki, M. Perez-Nieves +1 more
2022Primary Care Diabetes10 citations Open access
Semantic Scholar
Visualization of drug translocation in the nasal cavity and pharmacokinetic analysis on nasal drug absorption using positron emission tomography in the rat.
T. Shingaki, Yumiko Katayama, Takayoshi Nakaoka, Satsuki Irie +12 more
2016European journal of pharmaceutics and biopharmaceutics10 citations
Semantic Scholar
Real-world cross-sectional study evaluating patient characteristics, disease burden, and treatment approaches in people with obesity disease in Japan
Tomohiro Tanaka, Taisuke Kojima, Swathi Pathadka, Swarna Khare +3 more
2025Current Medical Research and Opinion9 citations Open access
Semantic Scholar
Long-term safety and effectiveness of biosimilar insulin glargine in Japanese patients with diabetes mellitus in routine clinical practice: results of a post-marketing safety study
T. Shingaki, Kentaro Taki, Momoha Koyanagi, S. Nagaoka +4 more
2020Current Medical Research and Opinion9 citations Open access
Semantic Scholar
Successful Healthcare Provider Strategies to Overcome Psychological Insulin Resistance in Japanese Patients with Type 2 Diabetes
Kentaro Okazaki, T. Shingaki, Z. Cai, M. Perez-Nieves +1 more
2019Diabetes Therapy9 citations Open access
Semantic Scholar
Extension of recovery time from fatigue by repeated rest with short‐term sleep during continuous fatigue load: Development of chronic fatigue model
A. Kanzaki, T. Okauchi, Di Hu, T. Shingaki +4 more
2016Journal of Neuroscience Research8 citations
Semantic Scholar
Efficacy and safety of once‐weekly tirzepatide in Japanese participants with type 2 diabetes who have obesity or overweight: Subpopulation analysis of the SURMOUNT‐2 trial
Toshimasa Yamauchi, Taro Asakura, T. Shingaki, Tomonori Oura +1 more
2025Diabetes, obesity and metabolism7 citations Open access
Semantic Scholar
Treatment satisfaction, safety, and effectiveness of biosimilar insulin glargine is comparable in patients with type 2 diabetes mellitus after switching from insulin glargine or insulin degludec: a post-marketing safety study
Kentaro Taki, Momoha Koyanagi, S. Nagaoka, T. Shingaki
2020Current Medical Research and Opinion7 citations
Semantic Scholar
Association of baseline characteristics with clinical outcomes of tirzepatide treatment in Japanese patients with obesity disease: A subgroup analysis of the SURMOUNT‐J trial
Koutaro Yokote, Yasushi Fukushima, T. Shingaki, Tomonori Oura +1 more
2025Diabetes, obesity and metabolism6 citations Open access
Semantic Scholar
Similar Intrapatient Blood Glucose Variability with LY2963016 and Lantus® Insulin Glargine in Patients with Type 1 (T1D) or Type 2 Diabetes, Including a Japanese T1D Subpopulation
Hiroshi Nishiyama, T. Shingaki, Yumi Suzuki, L. Ilag
2018Diabetes Therapy5 citations Open access
Semantic Scholar
Exploration of Antiemetics for Osteoporosis Therapy-Induced Nausea and Vomiting Using PET Molecular Imaging Analysis to Gastrointestinal Pharmacokinetics
T. Shingaki, Yumiko Katayama, Takayoshi Nakaoka, Tadayuki Takashima +6 more
2016Pharmaceutical Research4 citations
Semantic Scholar
Clinical and Humanistic Burden of Adult Obesity in Asia–Pacific: A Systematic Literature Review
E. Artime, Sarah Zimner-Rapuch, Roger Chen, Qiu-He Ji +7 more
2025Advances in Therapy3 citations Open access
Semantic Scholar
Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT‐1 Trial
Yasushi Ishigaki, Masamichi Yamada, T. Shingaki, Tomonori Oura +1 more
2026Obesity1 citations Open access
Semantic Scholar
Real-World Weight Loss Outcomes by Obesity Management Approaches in Japan: Descriptive Findings from the J-ORBIT Database Linked to Electronic Medical Records (J-ORBIT2)
Yushi Hirota, Seiji Nishikage, S. Osaga, A. Singh +5 more
2026Diabetes Therapy0 citations Open access
Semantic Scholar
Experience with Tirzepatide and Weight Management During and After a Clinical Trial in Japanese Patients with Obesity Disease: A Qualitative Study
A. Kiyosue, Manaka Sato, Zhihong Cai, Yasushi Fukushima +7 more
2026Advances in Therapy0 citations Open access
Semantic Scholar
Tirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial
Takumi Kitamoto, M. Yoshino, T. Shingaki, Tomonori Oura +2 more
2026Current Medical Research and Opinion0 citations Open access
Semantic Scholar
Medical costs attributable to obesity and obesity-related health disorders in a Japanese population using JMDC claims database.
Taisuke Kojima, S. Osaga, T. Aranishi, H. Fukuda +1 more
2026Journal of Medical Economics0 citations Open access
Semantic Scholar
Changes in Abdominal Adiposity and Associations With Metabolic Health Markers Following Tirzepatide in Japanese Participants With Obesity Disease: Results From the SURMOUNT-J Study.
Hironori Waki, Eiji Kaneyuki, T. Shingaki, Tomonori Oura +2 more
2026Endocrine Practice0 citations Open access
Semantic Scholar
Effect of Tirzepatide on Health‐Related Quality of Life in Japanese Patients With Obesity Disease: Patient‐Reported Outcomes From the SURMOUNT‐J Study
Hiroaki Masuzaki, Hirotaka Nagashima, T. Shingaki, Tomonori Oura +1 more
2026Diabetes, obesity and metabolism0 citations Open access
Semantic Scholar
Efficacy and safety of subgroup analysis stratified by baseline HbA 1 c in a Japanese phase 3 study of dulaglutide 0 . 75 mg compared with insulin glargine in patients with type 2 diabetes
Shizuka Kaneko, Tomonori Oura, T. Shingaki
20170 citations
Semantic Scholar
Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse
T. Shingaki, W. Hume, Tadayuki Takashima, Yumiko Katayama +7 more
2015Pharmaceutical Research0 citations
Semantic Scholar
Application of Molecular Imaging Technology for Innovative Drug Development Targeting to Brain
Yousuke Kanayama, T. Shingaki, H. Onoe, Yasuyoshi Watanabe
20130 citations Open access
Semantic Scholar
Evaluation of Oatp and Mrp2 Activities in Hepatobiliary Excretion Using Newly Developed Positron Emission Tomography (pet) Tracer, [ 11 C]dehydropravastatin, in Rats the Number of Supplemental Videos: 1 the Number of Words in the Discussion: 1,471 (word Limit: 1,500)
T. Shingaki, Tadayuki Takashima, Ryosuke Ijuin, Xuan Zhang +13 more
0 citations
Semantic Scholar

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