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D. Mirelman · SciRah

Researcher profile · Semantic Scholar

D. Mirelman

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D. Mirelman — researcher profile on SciRah

h-index: 51
Works: 180
Citations: 8,905

Most-cited papers

Antimicrobial properties of allicin from garlic.
S. Ankri, D. Mirelman
1999Microbes and infection1,264 citations Open access
Semantic Scholar
The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins.
A. Rabinkov, T. Miron, L. Konstantinovski, M. Wilchek +2 more
1998Biochimica et Biophysica Acta493 citations
Semantic Scholar
Effect of Purified Allicin, the Major Ingredient ofFreshly Crushed Garlic, on Cancer Cell Proliferation
K. Hirsch, M. Danilenko, J. Giat, T. Miron +5 more
2000Nutrition and Cancer267 citations
Semantic Scholar
Entamoeba histolytica cysteine proteinases with interleukin‐1 beta converting enzyme (ICE) activity cause intestinal inflammation and tissue damage in amoebiasis
Zhi Zhang, Lei Wang, Karl B. Seydel, E. Li +3 more
2000Molecular Microbiology148 citations
Semantic Scholar
Antimalarial Activity of Allicin, a Biologically Active Compound from Garlic Cloves
A. Coppi, Melissa A Cabinian, D. Mirelman, Photini Sinnis
2006Antimicrobial Agents and Chemotherapy143 citations
Semantic Scholar
Comparison of use of enzyme-linked immunosorbent assay-based kits and PCR amplification of rRNA genes for simultaneous detection of Entamoeba histolytica and E. dispar
D. Mirelman, Y. Nuchamowitz, T. Stolarsky
1997Journal of Clinical Microbiology142 citations Open access
Semantic Scholar
An ex-vivo Human Intestinal Model to Study Entamoeba histolytica Pathogenesis
D. Bansal, P. Avé, S. Kernéis, P. Frileux +9 more
2009PLoS Neglected Tropical Diseases141 citations Open access
Semantic Scholar
Transcriptional Silencing of an Amoebapore Gene in Entamoeba histolytica: Molecular Analysis and Effect on Pathogenicity
R. Bracha, Y. Nuchamowitz, D. Mirelman
2003Eukaryotic Cell134 citations Open access
Semantic Scholar
Antisense Inhibition of Expression of Cysteine Proteinases Affects Entamoeba histolytica-Induced Formation of Liver Abscess in Hamsters
S. Ankri, T. Stolarsky, R. Bracha, F. Padilla-Vaca +1 more
1999Infection and Immunity134 citations Open access
Semantic Scholar
The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats.
A. Elkayam, D. Mirelman, E. Peleg, M. Wilchek +4 more
2003American Journal of Hypertension125 citations Open access
Semantic Scholar
A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates.
T. Miron, Irina Shin, Guy Feigenblat, L. Weiner +3 more
2002Analytical Biochemistry119 citations
Semantic Scholar
Antisense inhibition of expression of cysteine proteinases does not affect Entamoeba histolytica cytopathic or haemolytic activity but inhibits phagocytosis
S. Ankri, T. Stolarsky, D. Mirelman
1998Molecular Microbiology118 citations Open access
Semantic Scholar
Antisense inhibition of amoebapore expression in Entamoeba histolytica causes a decrease in amoebic virulence
R. Bracha, Y. Nuchamowitz, M. Leippe, D. Mirelman
1999Molecular Microbiology112 citations Open access
Semantic Scholar
The major surface antigens of Entamoeba histolytica trophozoites are GPI-anchored proteophosphoglycans.
S. Moody-Haupt, J. Patterson, D. Mirelman, M. McConville
2000Journal of Molecular Biology111 citations
Semantic Scholar
The Antiatherogenic Effect of Allicin: Possible Mode of Action
Ayelet Gonen, D. Harats, A. Rabinkov, T. Miron +7 more
2006Pathobiology (Basel)110 citations
Semantic Scholar
Antisense inhibition of expression of the light subunit (35 kDa) of the Gal/GalNac lectin complex inhibits Entamoeba histolytica virulence
S. Ankri, F. Padilla-Vaca, T. Stolarsky, L. A. Koole +2 more
1999Molecular Microbiology110 citations Open access
Semantic Scholar
Transcriptional Silencing of Multiple Genes in Trophozoites of Entamoeba histolytica
R. Bracha, Y. Nuchamowitz, M. Anbar, D. Mirelman
2006PLoS Pathogens107 citations Open access
Semantic Scholar
Allicin up-regulates cellular glutathione level in vascular endothelial cells
Limor Horev-Azaria, Shlomit Eliav, Nira Izigov, S. Pri-Chen +7 more
2009European Journal of Nutrition95 citations
Semantic Scholar
Alliin Lyase (Alliinase) from Garlic (Allium sativum)
Aharon Rabimkov, Xiao-Zhu Zhu, G. Grafi, G. Galili +1 more
1994Applied Biochemistry and Biotechnology91 citations
Semantic Scholar
Down Regulation of Entamoeba histolytica Virulence by Monoxenic Cultivation with Escherichia coli O55 Is Related to a Decrease in Expression of the Light (35-Kilodalton) Subunit of the Gal/GalNAc Lectin
F. Padilla-Vaca, S. Ankri, R. Bracha, L. A. Koole +1 more
1999Infection and Immunity88 citations Open access
Semantic Scholar
Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis.
Yona Shadkchan, Einav Shemesh, D. Mirelman, T. Miron +3 more
2004Journal of Antimicrobial Chemotherapy87 citations
Semantic Scholar
A novel mechanism of neuroprotection: Blood glutamate grabber
J. Castillo, M. Loza, D. Mirelman, J. Bréa +3 more
2016Journal of Cerebral Blood Flow and Metabolism84 citations Open access
Semantic Scholar
Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras.
M. Patya, Muayad A. Zahalka, A. Vanichkin, A. Rabinkov +5 more
2004International Immunology84 citations Open access
Semantic Scholar
Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery.
T. Miron, M. Mironchik, D. Mirelman, M. Wilchek +1 more
2003Molecular Cancer Therapeutics78 citations
Semantic Scholar
Stress by Heat Shock Induces Massive Down Regulation of Genes and Allows Differential Allelic Expression of the Gal/GalNAc Lectin in Entamoeba histolytica
Christian Weber, G. Guigon, C. Bouchier, L. Frangeul +6 more
2006Eukaryotic Cell76 citations Open access
Semantic Scholar
Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.
F. Arditti, A. Rabinkov, T. Miron, Y. Reisner +3 more
2005Molecular Cancer Therapeutics76 citations
Semantic Scholar
Progress in research on Entamoeba histolytica pathogenesis.
J. Ackers, D. Mirelman
2006Current Opinion in Microbiology72 citations
Semantic Scholar
Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism
Young-Ah Lee, Y. Nam, A. Min, Kyeong Ah Kim +4 more
2014Parasite71 citations Open access
Semantic Scholar
Increased expression of the major cysteine proteinases by stable episomal transfection underlines the important role of EhCP5 for the pathogenicity of Entamoeba histolytica.
Manuela Tillack, N. Nowak, H. Lotter, R. Bracha +3 more
2006Molecular and biochemical parasitology (Print)71 citations
Semantic Scholar
Downregulation of an Entamoeba histolytica Rhomboid Protease Reveals Roles in Regulating Parasite Adhesion and Phagocytosis
Leigh A. Baxt, Elena Rastew, R. Bracha, D. Mirelman +1 more
2010Eukaryotic Cell70 citations Open access
Semantic Scholar
Expression of Amoebapores Is Required for Full Expression of Entamoeba histolytica Virulence in Amebic Liver Abscess but Is Not Necessary for the Induction of Inflammation or Tissue Damage in Amebic Colitis
Xiaochung Zhang, Zhi Zhang, D. Alexander, R. Bracha +2 more
2004Infection and Immunity69 citations Open access
Semantic Scholar
Two structures of alliinase from Alliium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor.
L. Shimon, A. Rabinkov, Irina Shin, T. Miron +3 more
2007Journal of Molecular Biology67 citations
Semantic Scholar
Allicin inhibits cell polarization, migration and division via its direct effect on microtubules.
M. Prager-Khoutorsky, I. Goncharov, A. Rabinkov, D. Mirelman +2 more
2007Cell Motility and the Cytoskeleton66 citations
Semantic Scholar
Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation.
Darcy M. Moncada, K. Keller, S. Ankri, D. Mirelman +1 more
2006Gastroenterology64 citations Open access
Semantic Scholar
Allicin inhibits SDF‐1α‐induced T cell interactions with fibronectin and endothelial cells by down‐regulating cytoskeleton rearrangement, Pyk‐2 phosphorylation and VLA‐4 expression
U. Sela, Sharon Ganor, I. Hecht, A. Brill +6 more
2004Immunology63 citations
Semantic Scholar
The effects of allicin and enalapril in fructose-induced hyperinsulinemic hyperlipidemic hypertensive rats.
A. Elkayam, D. Mirelman, E. Peleg, M. Wilchek +4 more
2001American Journal of Hypertension63 citations
Semantic Scholar
Asexual reproduction: 'Midwives' assist dividing amoebae
D. Biron, P. Libros, Dror Sagi, D. Mirelman +1 more
2001Nature55 citations
Semantic Scholar
Entamoeba histolytica expressing a dominant negative N-truncated light subunit of its gal-lectin are less virulent.
Uriel Katz, S. Ankri, T. Stolarsky, Y. Nuchamowitz +1 more
2002Molecular Biology of the Cell48 citations Open access
Semantic Scholar
Virulent and avirulent Entamoeba histolytica and E. dispar differ in their cell surface phosphorylated glycolipids
S. Moody, S. Becker, Y. Nuchamowitz, D. Mirelman
1997Parasitology48 citations
Semantic Scholar
Involvement of a Short Interspersed Element in Epigenetic Transcriptional Silencing of the Amoebapore Gene in Entamoeba histolytica
M. Anbar, R. Bracha, Y. Nuchamowitz, Yan Li +2 more
2005Eukaryotic Cell43 citations Open access
Semantic Scholar
Proteolysis of Enteric Cell Villin by Entamoeba histolytica Cysteine Proteinases*
T. Lauwaet, M. Oliveira, B. Callewaert, G. D. de Bruyne +6 more
2003Journal of Biological Chemistry42 citations Open access
Semantic Scholar
A virulence attenuated amoebapore-less mutant of Entamoeba histolytica and its interaction with host cells.
S. Bujanover, Uriel Katz, R. Bracha, D. Mirelman
2003International Journal of Parasitology39 citations
Semantic Scholar
Glutamate oxaloacetate transaminase: A new key in the dysregulation of glutamate in migraine patients
F. Campos, T. Sobrino, M. Pérez-Mato, X. Rodríguez-Osorio +4 more
2013Cephalalgia38 citations
Semantic Scholar
Thiol‐disulfide organization in alliin lyase (alliinase) from garlic (Allium sativum)
L. Weiner, Irina Shin, L. Shimon, T. Miron +4 more
2008Protein Science36 citations Open access
Semantic Scholar
Entamoeba histolytica Schaudinn, 1903 and Entamoeba dispar Brumpt, 1925: Differences in their Cell Surfaces and in the Bacteria-containing Vacuoles
P. Pimenta, L. S. Diamond, D. Mirelman
2002Journal of Eukaryotic Microbiology35 citations
Semantic Scholar
Alliinase (alliin lyase) from garlic (Alliium sativum) is glycosylated at ASN146 and forms a complex with a garlic mannose-specific lectin
A. Rabinkov, M. Wilchek, D. Mirelman
1995Glycoconjugate Journal35 citations
Semantic Scholar
Conjugates of daidzein-alliinase as a targeted pro-drug enzyme system against ovarian carcinoma
Elena Appel, A. Rabinkov, M. Neeman, F. Kohen +1 more
2011Journal of drug targeting (Print)34 citations
Semantic Scholar
Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome.
P. Ernsberger, Janean Johnson, T. Rosenthal, D. Mirelman +1 more
2007American Journal of Hypertension33 citations Open access
Semantic Scholar
Epigenetic transcriptional gene silencing in Entamoeba histolytica: insight into histone and chromatin modifications
Maya Huguenin, R. Bracha, T. Chookajorn, D. Mirelman
2009Parasitology29 citations
Semantic Scholar
Therapy of Murine Pulmonary Aspergillosis with Antibody-Alliinase Conjugates and Alliin
Elena Appel, A. Vallon-Eberhard, A. Rabinkov, O. Brenner +6 more
2009Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar

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