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I. Hecht · SciRah

Researcher profile · Semantic Scholar

I. Hecht

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I. Hecht — researcher profile on SciRah

h-index: 13
Works: 25
Citations: 621

Most-cited papers

Combinatorial signals by inflammatory cytokines and chemokines mediate leukocyte interactions with extracellular matrix
G. G. Vaday, Susanne Franitza, H. Schor, I. Hecht +4 more
2001Journal of Leukocyte Biology136 citations
Semantic Scholar
Discovery and Validation of Novel Peptide Agonists for G-protein-coupled Receptors*
R. Shemesh, A. Toporik, Zurit Levine, I. Hecht +9 more
2008Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis.
I. Hecht, L. Cahalon, R. Hershkoviz, A. Lahat +2 more
2003International Immunology71 citations
Semantic Scholar
A Novel Peptide Agonist of Formyl-Peptide Receptor-Like 1 (ALX) Displays Anti-Inflammatory and Cardioprotective Effects
I. Hecht, J. Rong, A. L. Sampaio, C. Hermesh +12 more
2009Journal of Pharmacology and Experimental Therapeutics63 citations
Semantic Scholar
Allicin inhibits SDF‐1α‐induced T cell interactions with fibronectin and endothelial cells by down‐regulating cytoskeleton rearrangement, Pyk‐2 phosphorylation and VLA‐4 expression
U. Sela, Sharon Ganor, I. Hecht, A. Brill +6 more
2004Immunology63 citations
Semantic Scholar
Halofuginone inhibits NF‐κB and p38 MAPK in activated T cells
M. Leiba, L. Cahalon, A. Shimoni, O. Lider +5 more
200640 citations Open access
Semantic Scholar
Heparin‐disaccharide affects T cells: inhibition of NF‐κB activation, cell migration, and modulation of intracellular signaling
I. Hecht, R. Hershkoviz, Shoham Shivtiel, T. Lapidot +3 more
2004Journal of Leukocyte Biology33 citations Open access
Semantic Scholar
ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses
I. Hecht, A. Toporik, Joseph R. Podojil, I. Vaknin +24 more
2018Journal of Immunology30 citations Open access
Semantic Scholar
BugSigDB captures patterns of differential abundance across a broad range of host-associated microbial signatures
L. Geistlinger, C. Mirzayi, F. Zohra, R. Azhar +17 more
2023Nature Biotechnology22 citations Open access
Semantic Scholar
ILDR2-Fc Is a Novel Regulator of Immune Homeostasis and Inducer of Antigen-Specific Immune Tolerance
Joseph R. Podojil, I. Hecht, Ming-Yi Chiang, I. Vaknin +5 more
2018Journal of Immunology22 citations Open access
Semantic Scholar
Halofuginone inhibits NF-kappaB and p38 MAPK in activated T cells.
M. Leiba, L. Cahalon, A. Shimoni, O. Lider +5 more
2006Journal of Leukocyte Biology18 citations
Semantic Scholar
Fibronectin-Associated Fas Ligand Rapidly Induces Opposing and Time-Dependent Effects on the Activation and Apoptosis of T Cells 1
A. Zanin-Zhorov, R. Hershkoviz, I. Hecht, L. Cahalon +1 more
2003Journal of Immunology16 citations Open access
Semantic Scholar
Disaccharides generated from heparan sulphate or heparin modulate chemokine‐induced T‐cell adhesion to extracellular matrix
R. Hershkoviz, H. Schor, A. Ariel, I. Hecht +3 more
2000Immunology16 citations Open access
Semantic Scholar
Multiomic evaluation of TEV-56278, a PD-1-targeted attenuated IL-2 molecule, in a human ex vivo tumor model and association with immune activation with enhanced effector CD8 T cell selectivity.
Ayala Tamir, Rukiye-Nazan Eraslan, E. O'Mara, G. Kumar +14 more
2025Journal of Clinical Oncology3 citations Open access
Semantic Scholar
Identification of novel immune checkpoints as targets for cancer immunotherapy
G. Rotman, O. Levy, A. Toporik, G. Cojocaru +16 more
2013Journal of Immunotherapy for Cancer3 citations Open access
Semantic Scholar
A novel peptide agonist of FPRL1 (ALX) displays anti-inflammatory and cardioprotective effects
I. Hecht, Rong Jiang, L. Andre, C. Sampaio +15 more
20083 citations
Semantic Scholar
BugSigDB: accelerating microbiome research through systematic comparison to published microbial signatures
L. Geistlinger, C. Mirzayi, F. Zohra, R. Azhar +17 more
2022medRxiv2 citations Open access
Semantic Scholar
CGEN-15001: a Novel B7-like regulator of immune homeostasis and inducer of Ag-specific tolerance
I. Hecht, G. Rotman, Ming-Yi Chiang, E. Neria +2 more
2017Journal of Immunology0 citations
Semantic Scholar
CGEN-15001, a Novel B7-like Protein, Controls Inflammation in a Translational Rheumatoid Arthritis (RA) Assay and Induces Treg Driven Long-Term Remission in an Autoimmune Disease Model
I. Hecht, A. Gilmour, C. Tange, D. McIntyre +8 more
20150 citations
Semantic Scholar
CGEN-15001, a Novel Immunomodulatory Fusion Protein of the B7 Family Induces Immune Tolerance and Shows Efficacy in Mouse Models of Rheumatoid Arthritis and Psoriasis.
I. Hecht, K. Mcnamee, A. Keren, Podojil +7 more
20140 citations
Semantic Scholar
Induction of immune tolerance by CGEN-15001, a novel immunomodulatory Fc fusion protein of the B7 family (THER5P.823)
I. Hecht, I. Vaknin, A. Oren, A. Toporik +9 more
2014Journal of Immunology0 citations
Semantic Scholar
Abstract B291: Identification of novel immune checkpoints and their implementation as mAb targets for cancer immunotherapy.
G. Cojocaru, O. Levy, A. Toporik, Liat Dassa +14 more
20130 citations
Semantic Scholar
OP0197 CGEN-15001, A Novel Negative Co-Stimulator Fusion Protein is Effective in the Collagen-Induced Arthritis Mouse Model of Rheumatoid Arthritis
I. Hecht, K. Mcnamee, I. Vaknin, A. Oren +4 more
20130 citations
Semantic Scholar
CellsEffects on the Activation and Apoptosis of T Induces Opposing and Time-Dependent Fibronectin-Associated Fas Ligand Rapidly
L. Cahalon, O. Lider, Alexandra Zanin-Zhorov, R. Hershkoviz +1 more
20030 citations
Semantic Scholar
Functional heterologous desensitization of T cell chemokine receptors CCR5 and CXCR4 ligand-induced desensitization of cellular signaling and chemotactic functions
I. Hecht, L. Cahalon, R. Hershkoviz, A. Lahat +2 more
20020 citations
Semantic Scholar

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O. Lider — researcher profile on SciRah
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