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M. Ikegami · SciRah

Researcher profile · Semantic Scholar

M. Ikegami

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M. Ikegami — researcher profile on SciRah

h-index: 82
Works: 443
Citations: 21K

Most-cited papers

MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation.
S. Madala, S. Schmidt, C. Davidson, M. Ikegami +2 more
2012American Journal of Respiratory Cell and Molecular Biology155 citations Open access
Semantic Scholar
LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice.
James P. Bridges, M. Ikegami, Lauren L. Brilli, Xue-Ni Chen +2 more
2010Journal of Clinical Investigation147 citations Open access
Semantic Scholar
C/EBPα is required for lung maturation at birth
Prithy C. Martis, J. Whitsett, Yan Xu, Anne-Karina T. Perl +2 more
2006141 citations Open access
Semantic Scholar
Bubble continuous positive airway pressure enhances lung volume and gas exchange in preterm lambs.
J. Pillow, N. Hillman, T. Moss, G. Polglase +4 more
2007American Journal of Respiratory and Critical Care Medicine137 citations Open access
Semantic Scholar
IL-1 mediates pulmonary and systemic inflammatory responses to chorioamnionitis induced by lipopolysaccharide.
S. Kallapur, I. Nitsos, T. Moss, G. Polglase +6 more
2009American Journal of Respiratory and Critical Care Medicine135 citations Open access
Semantic Scholar
Kruppel-like factor 5 is required for perinatal lung morphogenesis and function
Hua-Jing Wan, Feng-Ming Luo, S. Wert, Liqian Zhang +5 more
2008Development125 citations Open access
Semantic Scholar
Ibuprofen-Induced Patent Ductus Arteriosus Closure: Physiologic, Histologic, and Biochemical Effects on the Premature Lung
D. Mccurnin, S. Seidner, Ling-Yi L. Chang, N. Waleh +8 more
2008Pediatrics101 citations
Semantic Scholar
EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.
W. Hardie, C. Davidson, M. Ikegami, G. Leikauf +4 more
2008American Journal of Physiology - Lung cellular and Molecular Physiology99 citations
Semantic Scholar
Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates.
T. Sakagami, D. Beck, K. Uchida, Takuji Suzuki +13 more
2010American Journal of Respiratory and Critical Care Medicine98 citations Open access
Semantic Scholar
Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
T. Korfhagen, T. L. Le Cras, C. Davidson, S. Schmidt +3 more
2009American Journal of Respiratory Cell and Molecular Biology98 citations Open access
Semantic Scholar
Experimental amniotic fluid infection in sheep: effects of Ureaplasma parvum serovars 3 and 6 on preterm or term fetal sheep.
T. Moss, C. Knox, S. Kallapur, I. Nitsos +4 more
2008American Journal of Obstetrics and Gynecology88 citations Open access
Semantic Scholar
C/EBPalpha is required for lung maturation at birth.
Prithy C. Martis, J. Whitsett, Yan Xu, Anne-Karina T. Perl +2 more
2006Development88 citations
Semantic Scholar
Positive End-Expiratory Pressure and Tidal Volume During Initial Ventilation of Preterm Lambs
G. Polglase, N. Hillman, J. Pillow, F. Cheah +6 more
2008Pediatric Research85 citations Open access
Semantic Scholar
Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs.
E. Kuypers, J. Collins, B. Kramer, G. Ofman +10 more
2012American Journal of Physiology - Lung cellular and Molecular Physiology83 citations Open access
Semantic Scholar
Improved lung growth and function through hypoxia‐inducible factor in primate chronic lung disease of prematurity
Tiina M. Asikainen, Ling-Yi L. Chang, J. Coalson, B. K. Schneider +9 more
2006The FASEB Journal80 citations
Semantic Scholar
GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium.
H. Kida, M. Mucenski, A. R. Thitoff, T. L. Le Cras +4 more
2008American Journal of Pathology77 citations Open access
Semantic Scholar
Toll-Like Receptors and Agonist Responses in the Developing Fetal Sheep Lung
N. Hillman, T. Moss, I. Nitsos, B. Kramer +4 more
2008Pediatric Research76 citations
Semantic Scholar
Transcriptional Programs Controlling Perinatal Lung Maturation
Yan Xu, Yanhua Wang, V. Besnard, M. Ikegami +5 more
2012PLoS ONE75 citations Open access
Semantic Scholar
Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size.
James P. Bridges, Marie-Gabrielle Ludwig, Matthias Mueller, Bernd Kinzel +4 more
2013American Journal of Respiratory Cell and Molecular Biology70 citations Open access
Semantic Scholar
Deletion of Scap in Alveolar Type II Cells Influences Lung Lipid Homeostasis and Identifies a Compensatory Role for Pulmonary Lipofibroblasts*
V. Besnard, S. Wert, M. Stahlman, A. Postle +3 more
2009Journal of Biological Chemistry67 citations Open access
Semantic Scholar
SP-B and SP-C Containing New Synthetic Surfactant for Treatment of Extremely Immature Lamb Lung
A. Sato, M. Ikegami
2012PLoS ONE64 citations Open access
Semantic Scholar
Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis.
T. L. Le Cras, T. Korfhagen, C. Davidson, S. Schmidt +4 more
2010American Journal of Pathology63 citations Open access
Semantic Scholar
Calcineurin/Nfat signaling is required for perinatal lung maturation and function.
V. Davé, Tawanna Childs, Yan Xu, M. Ikegami +6 more
2006Journal of Clinical Investigation60 citations Open access
Semantic Scholar
Surfactant protein-D and surfactant inhibit endotoxin-induced pulmonary inflammation.
M. Ikegami, Elizabeth A. Scoville, Shawn N. Grant, T. Korfhagen +3 more
2007Chest58 citations
Semantic Scholar
Activation of Sterol-response Element-binding Proteins (SREBP) in Alveolar Type II Cells Enhances Lipogenesis Causing Pulmonary Lipotoxicity*
L. Plantier, V. Besnard, Yan Xu, M. Ikegami +4 more
2012Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.
V. Besnard, Yohei Matsuzaki, J. Clark, Yan Xu +7 more
2010American Journal of Physiology - Lung cellular and Molecular Physiology57 citations Open access
Semantic Scholar
Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells
Yan Xu, M. Ikegami, Yanhua Wang, Yohei Matsuzaki +1 more
2007BMC Genomics57 citations Open access
Semantic Scholar
Correction of Pulmonary Abnormalities in Sftpd-/- Mice Requires the Collagenous Domain of Surfactant Protein D*
P. Kingma, Liqian Zhang, M. Ikegami, K. Hartshorn +2 more
2006Journal of Biological Chemistry57 citations Open access
Semantic Scholar
Foxm1 Transcription Factor Is Critical for Proliferation and Differentiation of Clara Cells during Development of Conducting Airways
V. Ustiyan, S. Wert, M. Ikegami, I-Ching Wang +3 more
2012Developmental Biology55 citations Open access
Semantic Scholar
Surfactant protein-d inhibits lung inflammation caused by ventilation in premature newborn lambs.
A. Sato, J. Whitsett, R. Scheule, M. Ikegami
2010American Journal of Respiratory and Critical Care Medicine55 citations Open access
Semantic Scholar
An MRI system for imaging neonates in the NICU: initial feasibility study
Jean A. Tkach, N. Hillman, A. Jobe, W. Loew +11 more
2012Pediatric Radiology52 citations
Semantic Scholar
STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury.
M. Ikegami, A. Falcone, J. Whitsett
2008Journal of applied physiology52 citations
Semantic Scholar
Genomic Profile of Matrix and Vasculature Remodeling in TGF-α–Induced Pulmonary Fibrosis
W. Hardie, T. Korfhagen, M. Sartor, A. Prestridge +9 more
200752 citations Open access
Semantic Scholar
Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis.
S. Madala, T. Korfhagen, S. Schmidt, C. Davidson +6 more
2014American Journal of Physiology - Lung cellular and Molecular Physiology51 citations Open access
Semantic Scholar
Intratracheal recombinant surfactant protein d prevents endotoxin shock in the newborn preterm lamb.
M. Ikegami, Karen Carter, Kimberly A. Bishop, A. Yadav +4 more
2006American Journal of Respiratory and Critical Care Medicine49 citations Open access
Semantic Scholar
Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis.
S. Madala, R. Edukulla, S. Schmidt, C. Davidson +2 more
2014American Journal of Respiratory Cell and Molecular Biology47 citations Open access
Semantic Scholar
STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells.
Yohei Matsuzaki, V. Besnard, J. Clark, Yan Xu +3 more
2008American Journal of Respiratory Cell and Molecular Biology45 citations Open access
Semantic Scholar
Surfactant protein-D regulates the postnatal maturation of pulmonary surfactant lipid pool sizes.
M. Ikegami, Shawn N. Grant, T. Korfhagen, R. Scheule +1 more
2009Journal of applied physiology43 citations
Semantic Scholar
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.
W. Hardie, T. Korfhagen, M. Sartor, A. Prestridge +9 more
2007American Journal of Respiratory Cell and Molecular Biology41 citations
Semantic Scholar
Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.
E. Kramer, G. Deutsch, M. Sartor, W. Hardie +3 more
2007American Journal of Physiology - Lung cellular and Molecular Physiology40 citations
Semantic Scholar
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia.
Yan Xu, C. Saegusa, Angelica Schehr, Shawn N. Grant +2 more
2009American Journal of Physiology - Lung cellular and Molecular Physiology39 citations Open access
Semantic Scholar
Conditional Hypoxia Inducible Factor-1α Induction in Embryonic Pulmonary Epithelium Impairs Maturation and Augments Lymphangiogenesis
James P. Bridges, Sui Lin, M. Ikegami, J. Shannon
2011Developmental Biology38 citations Open access
Semantic Scholar
CCAAT/Enhancer-Binding Protein-α Suppresses Lung Tumor Development in Mice through the p38α MAP Kinase Pathway
A. Sato, N. Yamada, Y. Ogawa, M. Ikegami
2013PLoS ONE36 citations Open access
Semantic Scholar
Pulmonary surfactant surface tension influences alveolar capillary shape and oxygenation.
M. Ikegami, T. Weaver, Shawn N. Grant, J. Whitsett
2009American Journal of Respiratory Cell and Molecular Biology36 citations Open access
Semantic Scholar
IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lung.
S. Kallapur, T. Moss, R. Auten, I. Nitsos +6 more
2009American Journal of Physiology - Lung cellular and Molecular Physiology36 citations Open access
Semantic Scholar
Ureaplasma colonization of amniotic fluid and efficacy of antenatal corticosteroids for preterm lung maturation in sheep
T. Moss, I. Nitsos, C. Knox, G. Polglase +4 more
2009American Journal of Obstetrics and Gynecology35 citations Open access
Semantic Scholar
IL-1α Causes Lung Inflammation and Maturation by Direct Effects on Preterm Fetal Lamb Lungs
I. Sosenko, S. Kallapur, I. Nitsos, T. Moss +3 more
2006Pediatric Research35 citations
Semantic Scholar
Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice
S. Madala, Melissa D. Maxfield, C. Davidson, S. Schmidt +4 more
2011Pulmonary Medicine31 citations Open access
Semantic Scholar
Inhibitors of inflammation and endogenous surfactant pool size as modulators of lung injury with initiation of ventilation in preterm sheep
N. Hillman, S. Kallapur, J. Pillow, I. Nitsos +3 more
2010Respiratory Research31 citations Open access
Semantic Scholar
Stat3 Is Required for Cytoprotection of the Respiratory Epithelium during Adenoviral Infection1
Yohei Matsuzaki, Yan Xu, M. Ikegami, V. Besnard +4 more
2006Journal of Immunology31 citations
Semantic Scholar

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Yan Xu×13
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W. Hardie×10
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S. Kallapur — researcher profile on SciRah

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C. Davidson — researcher profile on SciRah

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I. Nitsos — researcher profile on SciRah

T. Korfhagen×9

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T. Korfhagen — researcher profile on SciRah

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T. Moss — researcher profile on SciRah

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A. Jobe — researcher profile on SciRah

T. L. Le Cras×7

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T. L. Le Cras — researcher profile on SciRah

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V. Besnard — researcher profile on SciRah