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O. Lequin · SciRah

Researcher profile · Semantic Scholar

O. Lequin

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O. Lequin — researcher profile on SciRah

h-index: 31
Works: 123
Citations: 5,145

Most-cited papers

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease
E. Quévrain, M. A. Maubert, C. Michon, F. Chain +22 more
2015Gut760 citations Open access
Semantic Scholar
Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis
P. Belin, Marie-Hélène Le Du, Alistair J. Fielding, O. Lequin +10 more
2009Proceedings of the National Academy of Sciences of the United States of America197 citations Open access
Semantic Scholar
Different membrane behaviour and cellular uptake of three basic arginine-rich peptides.
A. Walrant, Isabelle Correia, Chen-Yu Jiao, O. Lequin +6 more
2011Biochimica et Biophysica Acta149 citations Open access
Semantic Scholar
Evidence that biosynthesis of the neurotoxic alkaloids anatoxin-a and homoanatoxin-a in the cyanobacterium Oscillatoria PCC 6506 occurs on a modular polyketide synthase initiated by L-proline.
A. Méjean, S. Mann, T. Maldiney, Gaëlle Vassiliadis +2 more
2009Journal of the American Chemical Society135 citations
Semantic Scholar
Tryptophan within basic peptide sequences triggers glycosaminoglycan‐dependent endocytosis
Cherine Bechara, Manjula Pallerla, Y. Zaltsman, F. Burlina +3 more
2013The FASEB Journal121 citations
Semantic Scholar
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
P. Karoyan, V. Vieillard, Luis Gómez-Morales, Estelle Odile +5 more
2021Communications Biology104 citations Open access
Semantic Scholar
Dermaseptin S9, an α-Helical Antimicrobial Peptide with a Hydrophobic Core and Cationic Termini†
O. Lequin, A. Ladram, Ludovic Chabbert, F. Bruston +5 more
2006102 citations
Semantic Scholar
Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1.
S. Asgatay, Christine Champion, G. Marloie, Thierry Drujon +10 more
2014Journal of Medicinal Chemistry90 citations Open access
Semantic Scholar
Comparison of penetratin and other homeodomain-derived cell-penetrating peptides: interaction in a membrane-mimicking environment and cellular uptake efficiency.
S. Balayssac, F. Burlina, O. Convert, G. Bolbach +2 more
2006Biochemistry84 citations
Semantic Scholar
N- and Cα-Methylation in Biologically Active Peptides: Synthesis, Structural and Functional Aspects
S. Sagan, P. Karoyan, O. Lequin, G. Chassaing +1 more
200483 citations
Semantic Scholar
Temporin-SHf, a New Type of Phe-rich and Hydrophobic Ultrashort Antimicrobial Peptide*
Feten Abbassi, O. Lequin, Christophe Piesse, N. Goasdoué +3 more
2010Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Membrane interactions of two arginine-rich peptides with different cell internalization capacities.
A. Walrant, Alexander Vogel, Isabelle Correia, O. Lequin +4 more
2012Biochimica et Biophysica Acta78 citations Open access
Semantic Scholar
Distribution of Pico- and Nanosecond Motions in Disordered Proteins from Nuclear Spin Relaxation
S. N. Khan, Cyril Charlier, R. Augustyniak, N. Salvi +5 more
2015Biophysical Journal73 citations Open access
Semantic Scholar
Mechanism of antibacterial action of dermaseptin B2: interplay between helix-hinge-helix structure and membrane curvature strain.
Cécile Galanth, Feten Abbassi, O. Lequin, J. Ayala-Sanmartin +3 more
2009Biochemistry72 citations
Semantic Scholar
Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation.
L. Caillon, O. Lequin, Lucie Khemtemourian
2013Biochimica et Biophysica Acta69 citations Open access
Semantic Scholar
Insight into the mechanism of action of temporin-SHa, a new broad-spectrum antiparasitic and antibacterial agent
Zahid Raja, Sónia André, Feten Abbassi, V. Humblot +8 more
2017PLoS ONE61 citations Open access
Semantic Scholar
Rapid Synthesis of New DNMT Inhibitors Derivatives of Procainamide
L. Halby, Christine Champion, C. Sénamaud-Beaufort, Sophie Ajjan +11 more
2012ChemBioChem58 citations
Semantic Scholar
Biophysical Investigation of the Membrane-Disrupting Mechanism of the Antimicrobial and Amyloid-Like Peptide Dermaseptin S9
L. Caillon, J. Killian, O. Lequin, Lucie Khemtemourian
2013PLoS ONE47 citations Open access
Semantic Scholar
Solution structure and model membrane interactions of temporins-SH, antimicrobial peptides from amphibian skin. A NMR spectroscopy and differential scanning calorimetry study.
Feten Abbassi, Cécile Galanth, M. Amiche, Kazuko Saito +6 more
2008Biochemistry43 citations
Semantic Scholar
Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121
M. Fonvielle, Marie-Hélène Le Du, O. Lequin, A. Lecoq +6 more
2013Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Designed Glycopeptidomimetics Disrupt Protein-Protein Interactions Mediating Amyloid β-Peptide Aggregation and Restore Neuroblastoma Cell Viability.
J. Kaffy, D. Brinet, J. Soulier, Isabelle Correia +11 more
2016Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
3-Substituted Prolines: From Synthesis to Structural Applications, from Peptides to Foldamers
C. Mothes, C. Caumes, A. Guez, Héloise Boullet +7 more
2013Molecules36 citations Open access
Semantic Scholar
Sugar-based peptidomimetics inhibit amyloid β-peptide aggregation.
Bertrand Dorgeret, Lucie Khemtemourian, Isabelle Correia, J. Soulier +2 more
2011European journal of medicinal chemistry33 citations
Semantic Scholar
Dermaseptin S9, an alpha-helical antimicrobial peptide with a hydrophobic core and cationic termini.
O. Lequin, A. Ladram, Ludovic Chabbert, F. Bruston +5 more
2006Biochemistry31 citations Open access
Semantic Scholar
Investigating the role of GXXXG motifs in helical folding and self-association of plasticins, Gly/Leu-rich antimicrobial peptides.
L. Carlier, P. Joanne, Lucie Khemtemourian, C. Lacombe +3 more
2015Biophysical Chemistry29 citations
Semantic Scholar
Cholesterol modulates the interaction of the islet amyloid polypeptide with membranes
L. Caillon, Luminita Duma, O. Lequin, Lucie Khemtemourian
2014Molecular membrane biology26 citations Open access
Semantic Scholar
Incorporation of Non-canonical Amino Acids into 2,5-Diketopiperazines by Cyclodipeptide Synthases.
Nicolas Canu, P. Belin, R. Thai, Isabelle Correia +4 more
2018Angewandte Chemie25 citations
Semantic Scholar
Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure-Activity Relationship Studies.
Thomas Denèfle, Héloise Boullet, L. Herbi, C. Newton +14 more
2016Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Methods to determine slow diffusion coefficients of biomolecules. Applications to Engrailed 2, a partially disordered protein
R. Augustyniak, F. Ferrage, R. Paquin, O. Lequin +1 more
2011Journal of Biomolecular NMR24 citations Open access
Semantic Scholar
High affinity Grb2-SH3 domain ligand incorporating Cbeta-substituted prolines in a Sos-derived decapeptide.
Y. Jacquot, I. Broutin, Emeric Miclet, Magali Nicaise +7 more
2007Bioorganic & Medicinal Chemistry24 citations Open access
Semantic Scholar
CX3CL1 homo-oligomerization drives cell-to-cell adherence
M. Ostuni, P. Hermand, E. Saindoy, N. Guillou +12 more
2020Scientific Reports22 citations Open access
Semantic Scholar
Structure-activity relationships of sugar-based peptidomimetics as modulators of amyloid β-peptide early oligomerization and fibrillization.
J. Kaffy, D. Brinet, J. Soulier, Lucie Khemtemourian +4 more
2014European journal of medicinal chemistry22 citations
Semantic Scholar
Ligand-directed modification of active Matrix Metalloproteases: New activity-based probes with no photolabile group.
M. Kamińska, P. Bruyat, C. Malgorn, M. Doladilhe +12 more
2021Angewandte Chemie20 citations Open access
Semantic Scholar
Investigation of homeodomain membrane translocation properties: insights from the structure determination of engrailed-2 homeodomain in aqueous and membrane-mimetic environments.
L. Carlier, S. Balayssac, F. Cantrelle, Lucie Khemtemourian +3 more
2013Biophysical Journal20 citations Open access
Semantic Scholar
(R)‐α‐trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillation
Alexandra Botz, V. Gasparik, Emmanuelle Devillers, Anais R. F. Hoffmann +5 more
2015Biopolymers18 citations
Semantic Scholar
Antibody Recognition in multiple sclerosis and rett syndrome using a collection of linear and cyclic N‐glucosylated antigenic probes
F. Real-Fernández, M. Di Pisa, G. Rossi, N. Auberger +11 more
2015Biopolymers18 citations
Semantic Scholar
Chiral "basket handle" binaphthyl porphyrins: synthesis, catalytic epoxidation and NMR conformational studies
E. Rose, E. Gallo, Nicolas Raoul, Léa Bouché +3 more
201018 citations
Semantic Scholar
A single mutation on the human amyloid polypeptide modulates fibril growth and affects the mechanism of amyloid-induced membrane damage.
Anais R. F. Hoffmann, M. S. Saravanan, O. Lequin, J. Killian +1 more
2018Biochimica et Biophysica Acta - Biomembranes17 citations Open access
Semantic Scholar
Access to novel amino trifluoromethyl cyclopropane carboxylic acid derivatives
Massaba Keita, Rocco De Bona, Mickaël Dos Santos, O. Lequin +3 more
201317 citations
Semantic Scholar
What can be learnt from the comparison of multiscale brownian dynamics simulations, nuclear magnetic resonance and light scattering experiments on charged micelles?
V. Dahirel, B. Ancian, M. Jardat, G. Mériguet +2 more
201016 citations
Semantic Scholar
An hACE2 peptide mimic blocks SARS-CoV-2 Pulmonary Cell Infection
P. Karoyan, V. Vieillard, Estelle Odile, A. Denis +5 more
2020bioRxiv15 citations Open access
Semantic Scholar
Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches
Jerzy Witwinowski, M. Moutiez, Matthieu Coupet, Isabelle Correia +11 more
2019Scientific Reports15 citations Open access
Semantic Scholar
Novel Matrix Metalloproteinase 12 selective radiotracers for vascular molecular imaging
Jakub Toczek, Thomas Bordenave, K. Gona, Hye-Yeong Kim +10 more
2019Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif.
L. Carlier, A. Haase, Monica Y. Burgos Zepeda, E. Dassa +1 more
2012Journal of Structural Biology14 citations
Semantic Scholar
Biophysical studies of the interaction between calmodulin and the R²⁸⁷-T³¹¹ region of human estrogen receptor α reveals an atypical binding process.
L. Carlier, C. Byrne, Emeric Miclet, S. Bourgoin-Voillard +6 more
2012Biochemical and Biophysical Research Communications - BBRC14 citations
Semantic Scholar
Substituted Prolines: Syntheses and Applications in Structure—Activity Relationship Studies of Biologically Active Peptides
P. Karoyan, S. Sagan, O. Lequin, Jean Quancard +2 more
200614 citations
Semantic Scholar
Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor.
S. Sagan, Jean Quancard, O. Lequin, P. Karoyan +2 more
2005Chemistry and Biology14 citations Open access
Semantic Scholar
Characterization of the High-Affinity Drug Ligand Binding Site of Mouse Recombinant TSPO
Soria Iatmanen-Harbi, Lucile Sénicourt, V. Papadopoulos, O. Lequin +1 more
2019International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli
F. le Chevalier, Isabelle Correia, L. Mathéron, M. Babin +5 more
2020Microbial Cell Factories12 citations Open access
Semantic Scholar
Glaser oxidative coupling on peptides: stabilization of β-turn structure via a 1,3-butadiyne constraint.
N. Auberger, M. Di Pisa, M. Larregola, G. Chassaing +5 more
2014Bioorganic & Medicinal Chemistry12 citations
Semantic Scholar

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