K. Tieu

Most-cited papers

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
C. Vives-Bauzá, Chun Zhou, Yong Huang, M. Cui +14 more
2009Proceedings of the National Academy of Sciences of the United States of America1,664 citations Open access
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Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease
Du Wu, V. Jackson-Lewis, M. Vila, K. Tieu +5 more
2002Journal of Neuroscience1,214 citations Open access
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Glutathione dysregulation and the etiology and progression of human diseases
N. Ballatori, Suzanne M Krance, S. Notenboom, Shujie Shi +2 more
2009Biological chemistry1,041 citations Open access
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Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
N. Goldman, M. Chen, T. Fujita, Q. Xu +14 more
2010Nature Neuroscience845 citations Open access
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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
P. Teismann, K. Tieu, D. Choi, Du Wu +5 more
2003Proceedings of the National Academy of Sciences of the United States of America674 citations Open access
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NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
Du Wu, P. Teismann, K. Tieu, M. Vila +3 more
2003Proceedings of the National Academy of Sciences of the United States of America646 citations Open access
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A guide to neurotoxic animal models of Parkinson's disease.
K. Tieu
2011Cold Spring Harbor Perspectives in Medicine481 citations Open access
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Microglial exosomes facilitate α-synuclein transmission in Parkinson's disease.
Min Guo, Jian Wang, Yanxin Zhao, Yiwei Feng +4 more
2020Brain : a journal of neurology471 citations Open access
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D-β-Hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
K. Tieu, C. Perier, C. Caspersen, P. Teismann +7 more
2003469 citations Open access
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Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP
William T. Dauer, N. Kholodilov, M. Vila, A. Trillat +13 more
2002Proceedings of the National Academy of Sciences of the United States of America428 citations Open access
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The role of glial cells in Parkinson's disease
M. Vila, V. Jackson-Lewis, Christelle Guégan, Chu-Wu Du +4 more
2001Current Opinion in Neurology347 citations
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Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage.
C. Perier, K. Tieu, Christelle Guégan, C. Caspersen +6 more
2005Proceedings of the National Academy of Sciences of the United States of America316 citations Open access
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Pathogenic role of glial cells in Parkinson's disease
P. Teismann, K. Tieu, O. Cohen, D. Choi +5 more
2003Movement Disorders291 citations
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PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease
Fang Du, Qing Yu, Shi-Jun Yan, Gang Hu +6 more
2017Brain : a journal of neurology283 citations Open access
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Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity
D. Lovatt, Qi-Wu Xu, Wei Liu, T. Takano +4 more
2012Proceedings of the National Academy of Sciences of the United States of America283 citations Open access
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MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
S. Przedborski, K. Tieu, C. Perier, M. Vila
2004Journal of Bioenergetics and Biomembranes282 citations
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Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice
D. Choi, S. Pennathur, C. Perier, K. Tieu +7 more
2005Journal of Neuroscience271 citations Open access
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Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
P. Rappold, M. Cui, J. Grima, Rebecca Z. Fan +5 more
2014Nature Communications231 citations Open access
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Astrocytes and Therapeutics for Parkinson's Disease
P. Rappold, K. Tieu
2010Neurotherapeutics226 citations Open access
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Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1*
M. Cui, Xiangna Tang, W. V. Christian, Y. Yoon +1 more
2010Journal of Biological Chemistry214 citations Open access
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The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway
M. Cui, Radha V. Aras, W. V. Christian, P. Rappold +7 more
2009Proceedings of the National Academy of Sciences of the United States of America212 citations Open access
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Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3
P. Rappold, M. Cui, A. Chesser, J. Tibbett +5 more
2011Proceedings of the National Academy of Sciences of the United States of America211 citations Open access
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COX‐2 and Neurodegeneration in Parkinson's Disease
P. Teismann, M. Vila, D. Choi, K. Tieu +3 more
2003Annals of the New York Academy of Sciences191 citations
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Nitric Oxide and Reactive Oxygen Species in Parkinson's Disease
K. Tieu, H. Ischiropoulos, S. Przedborski
2003IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology188 citations Open access
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Metabolic reprogramming, oxidative stress, and pulmonary hypertension
Marissa D Pokharel, David P. Marciano, P. Fu, M. Franco +5 more
2023Redox Biology137 citations Open access
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Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease
Simone Bido, F. Soria, Rebecca Z. Fan, E. Bézard +1 more
2017Scientific Reports135 citations Open access
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Exosomes in Parkinson Disease
J. Pinnell, Mei Cui, K. Tieu
2020Journal of Neurochemistry123 citations Open access
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Silencing of the Pink1 Gene Expression by Conditional RNAi Does Not Induce Dopaminergic Neuron Death in Mice
Hongxia Zhou, B. Falkenburger, J. Schulz, K. Tieu +2 more
2007International Journal on Biological Sciences101 citations Open access
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Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin
Youngnam N. Jin, Yanxun V. Yu, Soner Gundemir, Chulman Jo +3 more
2013PLoS ONE99 citations Open access
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Tipping Points and Endogenous Determinants of Nigrostriatal Degeneration by MPTP.
Stefan Schildknecht, D. D. Di Monte, R. Pape, K. Tieu +1 more
2017TIPS - Trends in Pharmacological Sciences88 citations
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D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease
Soyeon Lim, A. Chesser, J. Grima, P. Rappold +3 more
2011PLoS ONE85 citations Open access
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Mitochondria: A Common Target for Genetic Mutations and Environmental Toxicants in Parkinson’s Disease
M. Helley, J. Pinnell, Carolina Sportelli, K. Tieu
2017Frontiers in Genetics83 citations Open access
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Differential effects of staurosporine and retinoic acid on the vulnerability of the SH‐SY5Y neuroblastoma cells: Involvement of Bcl‐2 and p53 proteins
K. Tieu, D. Zuo, Peter H. Yu
1999Journal of Neuroscience Research72 citations
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L‐3‐hydroxyacyl‐CoA dehydrogenase II protects in a model of Parkinson's disease
K. Tieu, C. Perier, M. Vila, C. Caspersen +6 more
2004Annals of Neurology57 citations
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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition
Rebecca Z. Fan, Min Guo, Shou-Qing Luo, Mei Cui +1 more
2019Acta Neuropathologica Communications53 citations Open access
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Manganese-Induced Parkinsonism: Evidence from Epidemiological and Experimental Studies
R. Lucchini, K. Tieu
2023Biomolecules42 citations Open access
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Free radical and nitric oxide toxicity in Parkinson's disease.
S. Przedborski, V. Jackson-Lewis, M. Vila, Chu-Wu Du +4 more
2003Advances in neurology40 citations
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Neurosteroid transport by the organic solute transporter OSTα-OSTβ
Fang Fang, W. V. Christian, Sadie G. Gorman, M. Cui +3 more
2010Journal of Neurochemistry39 citations Open access
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Glial cell response: A pathogenic factor in Parkinson’s disease
Du Wu, K. Tieu, O. Cohen, D. Choi +4 more
2002Journal of Neurovirology30 citations
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Microglial exosomes facilitate a -synuclein transmission in Parkinson’s disease
Min Guo, Jian Wang, Yanxin Zhao, Yiwei Feng +4 more
202025 citations
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Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Microglia from APOE Targeted Replacement Mice
Isha Mhatre-Winters, A. Eid, Yoonhee Han, K. Tieu +1 more
2022International Journal of Molecular Sciences23 citations Open access
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PINK 1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer ’ s disease
Fang Du, Qing Yu, Shi-Jun Yan, Gang Hu +6 more
201722 citations
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Inhibition of 6-hydroxydopamine-induced p53 expression and survival of neuroblastoma cells following interaction with astrocytes.
K. Tieu, P. Ashe, D. Zuo, Peter H. Yu
2001Neuroscience21 citations
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A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
Rebecca Z. Fan, Carolina Sportelli, Yanhao Lai, S. Salehe +5 more
2024Molecular Neurodegeneration18 citations Open access
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Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission.
Qing Lu, Xu-Tong Sun, Manivannan Yegambran, Wojciech Ornatowski +10 more
2023Journal of Biological Chemistry18 citations Open access
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Sex and APOE Genotype Alter the Basal and Induced Inflammatory States of Primary Astrocytes from Humanized Targeted Replacement Mice
Isha Mhatre-Winters, A. Eid, Yoonhee Han, K. Tieu +1 more
2023ASN Neuro17 citations Open access
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Loss of SOX18/CLAUDIN5 disrupts the pulmonary endothelial barrier in ventilator-induced lung injury
A. Garcia-Flores, Christine M. Gross, E. Zemskov, Qing Lu +3 more
2022Frontiers in Physiology15 citations Open access
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Local anesthetics induce autophagy in young permanent tooth pulp cells
H. Zhuang, D. Hu, Donald Singer, Jemma Victoria Walker +7 more
2015Cell Death Discovery14 citations Open access
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Neural Cell Adhesion Molecules
K. Tieu, P. Yu
199913 citations
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Cultured Astrocytes do not Release Adenosine during Hypoxic Conditions
T. Fujita, E. Williams, Tina K. Jensen, N. Smith +3 more
2012Journal of Cerebral Blood Flow and Metabolism9 citations Open access
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