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Xu-Tong Sun · SciRah

Researcher profile · Semantic Scholar

Xu-Tong Sun

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Xu-Tong Sun — researcher profile on SciRah

h-index: 25
Works: 70
Citations: 1,447

Most-cited papers

Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Hai-Yang Tang, A. Babicheva, Kimberly M. McDermott, Yali Gu +19 more
2017American Journal of Physiology - Lung cellular and Molecular Physiology154 citations Open access
Semantic Scholar
Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells
R. Rafikov, Xu-Tong Sun, O. Rafikova, Mary Louise Meadows +5 more
2015Redox Biology98 citations Open access
Semantic Scholar
Minor proteins and enzymes of the Drosophila eggshell matrix.
M. Fakhouri, Maggie Elalayli, Dan Sherling, J. D. Hall +4 more
2006Developmental Biology72 citations Open access
Semantic Scholar
Critical role of Brg1 member of the SWI/SNF chromatin remodeling complex during neurogenesis and neural crest induction in zebrafish
B. Eroglu, Guang-Hu Wang, Na-Xin Tu, Xu-Tong Sun +1 more
2006Developmental Dynamics71 citations Open access
Semantic Scholar
Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase.
Xu-Tong Sun, Sanjiv Kumar, Shruti Sharma, S. Aggarwal +11 more
2014American Journal of Respiratory Cell and Molecular Biology69 citations Open access
Semantic Scholar
LPS‐induced Acute Lung Injury Involves NF‐&kgr;B‐mediated Downregulation of SOX18
Christine M. Gross, M. Kellner, Ting Wang, Qing Lu +17 more
2017American Journal of Respiratory Cell and Molecular Biology68 citations Open access
Semantic Scholar
Down‐regulation of WNK1 protein kinase in neural progenitor cells suppresses cell proliferation and migration
Xu-Tong Sun, Luo-Yi Gao, Robert K. Yu, G. Zeng
2006Journal of Neurochemistry65 citations Open access
Semantic Scholar
The mitochondrial redistribution of eNOS is involved in lipopolysaccharide induced inflammasome activation during acute lung injury
Hui Wang, Xu-Tong Sun, Qing Lu, E. Zemskov +5 more
2021Redox Biology52 citations Open access
Semantic Scholar
Disruption of Endothelial Cell Mitochondrial Bioenergetics in Lambs with Increased Pulmonary Blood Flow
Xu-Tong Sun, Shruti Sharma, S. Fratz, Sanjiv Kumar +11 more
2013Antioxidants and Redox Signaling48 citations Open access
Semantic Scholar
Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism
Qing Lu, V. Harris, R. Rafikov, Xu-Tong Sun +2 more
2015Redox Biology47 citations Open access
Semantic Scholar
Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics
Qing Lu, E. Zemskov, Xu-Tong Sun, Hui Wang +11 more
2020Redox Biology44 citations Open access
Semantic Scholar
PPAR-γ Regulates Carnitine Homeostasis and Mitochondrial Function in a Lamb Model of Increased Pulmonary Blood Flow
Shruti Sharma, Xu-Tong Sun, R. Rafikov, Sanjiv Kumar +6 more
2012PLoS ONE44 citations Open access
Semantic Scholar
Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity.
Sanjiv Kumar, Xu-Tong Sun, S. Wedgwood, S. Black
2008American Journal of Physiology - Lung cellular and Molecular Physiology44 citations Open access
Semantic Scholar
L-Carnitine Preserves Endothelial Function in a Lamb Model of Increased Pulmonary Blood Flow
Shruti Sharma, A. Aramburo, R. Rafikov, Xu-Tong Sun +9 more
2013Pediatric Research42 citations Open access
Semantic Scholar
TGF-β1 attenuates mitochondrial bioenergetics in pulmonary arterial endothelial cells via the disruption of carnitine homeostasis
Xu-Tong Sun, Qing Lu, M. Yegambaram, Sanjiv Kumar +5 more
2020Redox Biology40 citations Open access
Semantic Scholar
Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation.
Jason T. Boehme, Xu-Tong Sun, K. Tormos, Wen-Hui Gong +8 more
2016American Journal of Physiology. Heart and Circulatory Physiology38 citations Open access
Semantic Scholar
Asymmetric Dimethylarginine Induces Endothelial Nitric-oxide Synthase Mitochondrial Redistribution through the Nitration-mediated Activation of Akt1*
R. Rafikov, O. Rafikova, S. Aggarwal, Christine M. Gross +4 more
2012Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Oxygen Glucose Deprivation in Rat Hippocampal Slice Cultures Results in Alterations in Carnitine Homeostasis and Mitochondrial Dysfunction
Thomas F. Rau, Qing Lu, Shruti Sharma, Xu-Tong Sun +7 more
2012PLoS ONE35 citations Open access
Semantic Scholar
RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury
Ting Wang, M. Yegambaram, Christine M. Gross, Xu-Tong Sun +7 more
2020Redox Biology31 citations Open access
Semantic Scholar
PRESERVING MITOCHONDRIAL FUNCTION PREVENTS THE PROTEASOMAL DEGRADATION OF GTP CYCLOHYDROLASE I
Shruti Sharma, Xu-Tong Sun, Sanjiv Kumar, R. Rafikov +7 more
2012Free Radical Biology & Medicine31 citations Open access
Semantic Scholar
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.
Xu-Tong Sun, S. Fratz, Shruti Sharma, Ya-Li Hou +14 more
2011American Journal of Respiratory Cell and Molecular Biology29 citations Open access
Semantic Scholar
Hydrogen Peroxide Decreases Endothelial Nitric Oxide Synthase Promoter Activity through the Inhibition of Sp1 Activity
Sanjiv Kumar, Xu-Tong Sun, D. Wiseman, Jing-Yi Tian +3 more
2009DNA and Cell Biology28 citations Open access
Semantic Scholar
SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics
S. Sangam, Xu-Tong Sun, Tae-Hwi Schwantes-An, M. Yegambaram +25 more
2023American Journal of Respiratory and Critical Care Medicine26 citations Open access
Semantic Scholar
Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling
Rebecca Johnson Kameny, S. Datar, Jason B. Boehme, Catherine J. Morris +12 more
2019American Journal of Respiratory Cell and Molecular Biology26 citations Open access
Semantic Scholar
Purification and characterization of a putative vitellogenin from the ovary of amphioxus (Branchiostoma belcheri tsingtaunese).
Xu-Tong Sun, Shi-Cui Zhang
2001Comparative Biochemistry and Physiology Part B Comparative Biochemistry25 citations
Semantic Scholar
Immunohistochemical localization of vitellogenin in the hepatic diverticulum of the amphioxus Branchiostoma belcheri tsingtauense, with implications for the origin of the liver
Lihau Han, Shi-Cui Zhang, Yong-Jun Wang, Xu-Tong Sun
200624 citations
Semantic Scholar
Ca2+/Calmodulin-Dependent Protein Kinase II Contributes to Hypoxic Ischemic Cell Death in Neonatal Hippocampal Slice Cultures
Qing Lu, V. Harris, Xu-Tong Sun, Ya-Li Hou +1 more
2013PLoS ONE22 citations Open access
Semantic Scholar
RESEARCH ARTICLE Ion Channels and Transporters in Lung Function and Disease Capsaicin-induced Ca 2 (cid:2) signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH
Shanshan Song, Ramon Ayon, Aya Yamamura, H. Yamamura +13 more
201721 citations
Semantic Scholar
Role of Carnitine Acetyl Transferase in Regulation of Nitric Oxide Signaling in Pulmonary Arterial Endothelial Cells
Shruti Sharma, Xu-Tong Sun, Saurabh Agarwal, R. Rafikov +3 more
2012International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
Nitration-mediated activation of the small GTPase RhoA stimulates cellular glycolysis through enhanced mitochondrial fission.
Qing Lu, Xu-Tong Sun, Manivannan Yegambran, Wojciech Ornatowski +10 more
2023Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Estradiol increases guanosine 5'-triphosphate cyclohydrolase expression via the nitric oxide-mediated activation of cyclic adenosine 5'-monophosphate response element binding protein.
Xu-Tong Sun, Sanjiv Kumar, Jing-Yi Tian, S. Black
2009Endocrinology15 citations Open access
Semantic Scholar
GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP.
Sanjiv Kumar, Xu-Tong Sun, Shruti Sharma, S. Aggarwal +3 more
2009American Journal of Physiology - Lung cellular and Molecular Physiology14 citations Open access
Semantic Scholar
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury
Sanjiv Kumar, Xu-Tong Sun, S. Noonepalle, Qing Lu +17 more
2016Free Radical Biology & Medicine13 citations Open access
Semantic Scholar
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
Xu-Tong Sun, M. Kellner, A. Desai, Ting Wang +11 more
2016American Journal of Respiratory Cell and Molecular Biology11 citations Open access
Semantic Scholar
Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system
Xiao-Min Wu, Xu-Tong Sun, Shruti Sharma, Qing Lu +5 more
2020Nitric oxide10 citations Open access
Semantic Scholar
Endothelin-1 acutely increases nitric oxide production via the calcineurin mediated dephosphorylation of Caveolin-1.
M. Yegambaram, Sanjiv Kumar, Xiao-Min Wu, Qing Lu +8 more
2023Nitric oxide7 citations
Semantic Scholar
Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation
Jason T. Boehme, Xu-Tong Sun, Q. Lu, Jubilee Barton +7 more
2023Nitric oxide4 citations Open access
Semantic Scholar
Ion Channels and Transporters in Lung Function and Disease Capsaicin-induced Ca 2 signaling is enhanced via upregulated TRPV 1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH
Shanshan Song, Ramon Ayon, A. Yamamura, H. Yamamura +13 more
20173 citations
Semantic Scholar
An ascidian RING finger gene is specifically expressed in a single cell of larval ocellus.
Xu-Tong Sun, M. Okuyama, K. Miyazaki, Shi-Cui Zhang +1 more
2003Gene2 citations
Semantic Scholar
Abstract 14973: Upregulated Sphingosine-1-Phosphate Receptor 3 Disrupts Endothelial Cell Barrier and Mitochondrial Network Dynamics
Jialin Wu, Ying Liang, Xu-Tong Sun, Qing Lu +3 more
2022Circulation1 citations
Semantic Scholar
Optimized scandium doping in Al₂Mo₃O₁₂ with NP co-doped carbon coating for enhanced low-temperature lithium storage
De-Heng Li, Xu-Tong Sun, Hao Li, De-Xiang Xin +6 more
2026Journal of Energy Storage0 citations Open access
Semantic Scholar
Synergistic effect of carbon and MnO2 coated Na3V2(PO4)2F3 cathode for high-performance sodium-ion batteries
Jia-Qi Pan, Shaokang Guo, Xingyu Ni, Xu-Tong Sun +5 more
2026Journal of Energy Storage0 citations Open access
Semantic Scholar
Autophagy plays a key role in hyper-proliferative phenotype in pulmonary vascular diseases
Wojciech Ornatowski, Qing Lu, Xu-Tong Sun, A. Flores +6 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
Role Of Mitochondrial ROS and HIF Signaling in the Metabolic Reprogramming Associated with Increased Sox18 Expression
M. Yegambaram, Xu-Tong Sun, Qing Lu, A. Flores +7 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
Abstract 13625: Autophagy Plays a Key Role in the Loss of Nitric Oxide Signaling and Endothelial Dysfunction in Pulmonary Vascular Diseases
Ying Liang, Wojciech Ornatowski, Qing Lu, Xu-Tong Sun +7 more
2022Circulation0 citations
Semantic Scholar
VILI Induced Nitration of RhoA Disrupts Mitochondrial Function Through Increased Generation of Reactive Oxygen Species
A. Flores, Qing Lu, Xu-Tong Sun, S. Black
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
The anti-apoptotic protein, Survivin induces a shift in endothelial cell in carbon metabolism through a mitochondrial-ROS-dependent increase in HIF-1a signaling
Qing Lu, Xu-Tong Sun, Jamie E. Soto, Haiwei Gu +6 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
Increased Mitochondrial Fission Induces a Warburg Phenotype Via the Hydrogen Peroxide Mediated inhibition of Prolyl Hydroxylase 2 (PHD2) in Pulmonary Arterial Endothelial Cells
Xu-Tong Sun, M. Yegambaram, Qing Lu, A. Flores +4 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
Mitochondrial redistribution of eNOS is regulated by CHIP mediated disruption of Dimerization
Xu-Tong Sun, Santiago Moreno, M. Yegambaram, Qing Lu +5 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar
NAMPT induces Mitochondrial and Barrier Dysfunction in Pulmonary Endothelial Cells
Marissa D Pokharel, A. Flores, Qing Lu, Xu-Tong Sun +3 more
2022Free Radical Biology & Medicine0 citations
Semantic Scholar

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