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R. Fontijn · SciRah

Researcher profile · Semantic Scholar

R. Fontijn

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R. Fontijn — researcher profile on SciRah

h-index: 28
Works: 64
Citations: 3,660

Most-cited papers

Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2).
R. Dekker, S. van Soest, R. Fontijn, Sonia Salamanca +4 more
2002Blood745 citations Open access
Semantic Scholar
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis.
L. Hawinkels, K. Zuidwijk, H. Verspaget, E. D. de Jonge-Muller +7 more
2008European Journal of Cancer225 citations
Semantic Scholar
Fluid shear stress stimulates incorporation of hyaluronan into endothelial cell glycocalyx.
M. Gouverneur, J. Spaan, H. Pannekoek, R. Fontijn +1 more
2006American Journal of Physiology. Heart and Circulatory Physiology208 citations
Semantic Scholar
Rosuvastatin Reduces Atherosclerosis Development Beyond and Independent of Its Plasma Cholesterol–Lowering Effect in APOE*3-Leiden Transgenic Mice: Evidence for Antiinflammatory Effects of Rosuvastatin
R. Kleemann, H. Princen, J. Emeis, J. Jukema +4 more
2003Circulation193 citations Open access
Semantic Scholar
Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes.
A. Horrevoets, R. Fontijn, A. V. van Zonneveld, C. D. de Vries +2 more
1999Blood181 citations
Semantic Scholar
The Human Kinesin-Like Protein RB6K Is under Tight Cell Cycle Control and Is Essential for Cytokinesis
R. Fontijn, B. Goud, A. Echard, F. Jollivet +3 more
2001Molecular and Cellular Biology174 citations Open access
Semantic Scholar
The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.
H. Monajemi, R. Fontijn, H. Pannekoek, A. Horrevoets
2002Genomics169 citations
Semantic Scholar
Monovalent nickel in hydrogenase from Chromatium vinosum
J. W. Van Der Zwaan, S. P. Albracht, R. Fontijn, E. C. Slater
1985FEBS Letters139 citations
Semantic Scholar
Domains involved in multimer assembly of von willebrand factor (vWF): multimerization is independent of dimerization.
J. Voorberg, R. Fontijn, J. V. Van Mourik, H. Pannekoek
1990EMBO Journal134 citations Open access
Semantic Scholar
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes
W. J. M. van de Ven, J. Voorberg, R. Fontijn, H. Pannekoek +4 more
1990Molecular Biology Reports118 citations
Semantic Scholar
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium.
R. Boon, T. Leyen, R. Fontijn, J. Fledderus +4 more
2010Blood110 citations Open access
Semantic Scholar
SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function.
R. Fontijn, O. Volger, J. Fledderus, A. Reijerkerk +2 more
2008American Journal of Physiology. Heart and Circulatory Physiology96 citations
Semantic Scholar
Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage.
R. Szulcek, C. Happé, N. Rol, R. Fontijn +15 more
2016American Journal of Respiratory and Critical Care Medicine90 citations Open access
Semantic Scholar
Distinctive expression of chemokines and transforming growth factor-beta signaling in human arterial endothelium during atherosclerosis.
O. Volger, J. Fledderus, N. Kisters, R. Fontijn +7 more
2007American Journal of Pathology81 citations Open access
Semantic Scholar
Spatial segregation of transport and signalling functions between human endothelial caveolae and lipid raft proteomes.
R. Sprenger, R. Fontijn, J. van Marle, H. Pannekoek +1 more
2006Biochemical Journal79 citations Open access
Semantic Scholar
Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Claudio Derada Troletti, R. Fontijn, E. Gowing, M. Charabati +8 more
2019Cell Death and Disease78 citations Open access
Semantic Scholar
EPR evidence for direct interaction of carbon monoxide with nickel in hydrogenase from Chromatium vinosum
J. W. Van Der Zwaan, S. P. Albracht, R. Fontijn, Y. B. M. Roelofs
198664 citations
Semantic Scholar
Molecular cloning of the rDNA of Saccharomyces rosei and comparison of its transcription initiation region with that of Saccharomyces carlsbergensis.
M. Verbeet, J. Klootwijk, H. van Heerikhuizen, R. Fontijn +2 more
1983Gene62 citations
Semantic Scholar
Endothelial CD81 is a marker of early human atherosclerotic plaques and facilitates monocyte adhesion.
J. Rohlena, O. Volger, J. V. van Buul, L. Hekking +6 more
2009Cardiovascular Research61 citations
Semantic Scholar
EPR Spectrum at 4, 9 and 35 GHz of hydrogenase from Chromatium vinosum. Direct evidence for spin-spin interaction between Ni(III) and the ironsulphur cluster
S. P. Albracht, J. W. Van Der Zwaan, R. Fontijn
198461 citations
Semantic Scholar
Galectin-2 Induces a Proinflammatory, Anti-Arteriogenic Phenotype in Monocytes and Macrophages
C. Yıldırım, D. Vogel, M. Hollander, J. Baggen +11 more
2015PLoS ONE60 citations Open access
Semantic Scholar
A new EPR signal of nickel in Methanobacterium thermoautotrophicum
S. P. Albracht, D. Ankel-Fuchs, J. W. Van Der Zwaan, R. Fontijn +1 more
198647 citations
Semantic Scholar
Direct evidence for sulphur as a ligand to nickel in hydrogenase: an EPR study of the enzyme from Wolinella succinogenes enriched in 33S
S. P. Albracht, A. Kröger, J. W. Van Der Zwaan, G. Unden +3 more
198646 citations
Semantic Scholar
Elevated monocyte-specific type I interferon signalling correlates positively with cardiac healing in myocardial infarct patients but interferon alpha application deteriorates myocardial healing in rats
E. N. ter Horst, P. Krijnen, N. Hakimzadeh, L. Robbers +15 more
2018Basic Research in Cardiology45 citations Open access
Semantic Scholar
Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells.
R. Boon, Carmen Urbich, A. Fischer, R. Fontijn +4 more
2011European Heart Journal45 citations
Semantic Scholar
Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy
A. Chakraborty, A. Kamermans, B. J. van Het Hof, Kitty C. M. Castricum +8 more
2018Brain : a journal of neurology42 citations Open access
Semantic Scholar
Limited contribution of claudin-5-dependent tight junction strands to endothelial barrier function.
R. Fontijn, J. Rohlena, J. van Marle, H. Pannekoek +1 more
2006European Journal of Cell Biology34 citations
Semantic Scholar
Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation
David Roig-Carles, Eduard Willms, R. Fontijn, Sarai Martinez-Pacheco +7 more
2021Pharmaceutics32 citations Open access
Semantic Scholar
Vascular Endothelial Growth Factor remains unchanged in cerebrospinal fluid of patients with Alzheimer’s disease and vascular dementia
A. Chakraborty, Madhurima Chatterjee, H. Twaalfhoven, M. del Campo Milan +5 more
2018Alzheimer's Research & Therapy28 citations Open access
Semantic Scholar
On the anomalous temperature behaviour of the EPR signal of monovalent nickel in hydrogenase.
J. W. Van Der Zwaan, S. P. Albracht, R. Fontijn, P. Mul
1987European Journal of Biochemistry28 citations
Semantic Scholar
Expression of Nitric Oxide-Transporting Aquaporin-1 Is Controlled by KLF2 and Marks Non-Activated Endothelium In Vivo
R. Fontijn, O. Volger, T. C. van der Pouw Kraan, A. Doddaballapur +4 more
2015PLoS ONE24 citations Open access
Semantic Scholar
Destruction and reconstitution of the activity of hydrogenase from Chromatium vinosum
S. P. Albracht, R. Fontijn, J. W. Van Der Zwaan
198524 citations
Semantic Scholar
A conserved sequence element is present around the transcription initiation site for RNA polymerase A in Saccharomycetoideae.
M. Verbeet, J. Klootwijk, H. van Heerikhuizen, R. Fontijn +2 more
1984Nucleic Acids Research23 citations Open access
Semantic Scholar
Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner.
Claudio Derada Troletti, Melissa A. Lopes Pinheiro, M. Charabati, E. Gowing +7 more
2017Brain, behavior, and immunity22 citations
Semantic Scholar
Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Claudio Derada Troletti, R. Fontijn, E. Gowing, M. Charabati +8 more
2019Cell Death and Disease19 citations Open access
Semantic Scholar
Adipose tissue-derived stromal cells acquire endothelial-like features upon reprogramming with SOX18.
R. Fontijn, J. Favre, B. Naaijkens, Elisa Meinster +8 more
2014Stem Cell Research18 citations Open access
Semantic Scholar
Evolution of yeast ribosomal DNA: Molecular cloning of the rDNA units of Kluyveromyces lactis and Hansenula wingei and their comparison with the rDNA units of other Saccharomycetoideae
M. Verbeet, H. van Heerikhuizen, J. Klootwijk, R. Fontijn +1 more
2004Molecular and General Genetics MGG17 citations
Semantic Scholar
Hemostasis, Thrombosis, and Vascular Biology Vascular Endothelial Genes That Are Responsive to Tumor Necrosis Factor-␣ in Vitro Are Expressed in Atherosclerotic Lesions, including Inhibitor of Apoptosis Protein-1, Stannin, and Two Novel Genes
A. Horrevoets, R. Fontijn, A. V. van Zonneveld, C. D. de Vries +2 more
199814 citations
Semantic Scholar
Profiling the unique protective properties of intracranial arterial endothelial cells
D. Hermkens, Olga C G Stam, N. D. de Wit, R. Fontijn +6 more
2019Acta Neuropathologica Communications12 citations Open access
Semantic Scholar
Palmitic acid increases pro-oxidant adaptor protein p66Shc expression and affects vascularization factors in angiogenic mononuclear cells: Action of resveratrol.
J. Favre, C. Yıldırım, T. Leyen, Weena J. Y. Chen +11 more
2015Vascular pharmacology9 citations
Semantic Scholar
IFN-β affects the angiogenic potential of circulating angiogenic cells by activating calpain 1.
C. Yıldırım, J. Favre, E. Weijers, R. Fontijn +6 more
2015American Journal of Physiology. Heart and Circulatory Physiology6 citations Open access
Semantic Scholar
2P-0562 Rosuvastatin reduces atherosclerosis development beyond and independently of its plasma cholesterol-lowering effect in APOE∗3-Leiden transgenic mice. Evidence for anti-inflammatory effects of rosuvastatin
L. Havekes, R. Kleemann, J. Emeis, R. Fontijn +3 more
20031 citations
Semantic Scholar
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)
Hans Pannekoek, A. Horrevoets, R. Dekker, S. van Soest +4 more
20021 citations
Semantic Scholar
CHAPTER 5 Delayed microvascular shear adaptation in Pulmonary Arterial Hypertension : role of Platelet Endothelial Cell Adhesion Molecul-1 cleavage
R. Szulcek, C. Happé, N. Rol, R. Fontijn +15 more
20160 citations
Semantic Scholar
Chapter 6 Diaphanous Related Formin 2 ( DRF 2 ) is Essential for KLF 2-induced Resistance of Endothelial Cells to Flow
E. Valent, R. Fontijn, T. Leyen, R. Szulcek +4 more
20160 citations
Semantic Scholar
Hydrocortisone and M-CSF promote in vitro education of pro-angiogenic monocytes
C. Yıldırım, J. Favre, J. Baggen, R. Fontijn +5 more
20150 citations
Semantic Scholar
Time-resolved study of endothelial shear-responsiveness in pulmonary arterial hypertension
R. Szulcek, C. Happé, N. Rol, R. Fontijn +7 more
20150 citations
Semantic Scholar
provides a high-throughput alternative to in vivo enhancer analyses Single site-specific integration targeting coupled with embryonic stem cell differentiation
R. Rosenberg, J. Kuivenhoven, Valerie Evans, A. Hatzopoulos +16 more
20150 citations
Semantic Scholar
Galectin-2 skews monocyte/macrophages to a pro-inflammatory, anti-arteriogenic phenotype
C. Yıldırım, D. Vogel, M. Hollander, J. Baggen +13 more
20140 citations
Semantic Scholar
Abstract 530: Impaired Ability of Pulmonary Microvascular, but Not Macrovascular, Endothelial Cells From Patients With Pulmonary Arterial Hypertension to Respond to High Shear Stress
R. Szulcek, R. Fontijn, J. V. van Bezu, Anton Vonk Noordegraaf +3 more
2014Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar

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