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A. Hatzopoulos · SciRah

Researcher profile · Semantic Scholar

A. Hatzopoulos

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A. Hatzopoulos — researcher profile on SciRah

h-index: 49
Works: 127
Citations: 8,477

Most-cited papers

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Ischemic Heart Failure: The FOCUS-CCTRN Trial
E. Perin, J. Willerson, C. Pepine, T. Henry +39 more
2012Journal of the American Medical Association (JAMA)491 citations Open access
Semantic Scholar
Effect of Intracoronary Delivery of Autolologous Bone Marrow Mononuclear Cells Two to Three Weeks Following Acute Myocardial Infarction on Left-Ventricular Function: The LateTIME Randomized Trial
J. Traverse, T. Henry, S. Ellis, C. Pepine +41 more
2011Journal of the American Medical Association (JAMA)442 citations Open access
Semantic Scholar
Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial
J. Traverse, T. Henry, C. Pepine, J. Willerson +43 more
2012Journal of the American Medical Association (JAMA)421 citations Open access
Semantic Scholar
Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition
Omonigho Aisagbonhi, M. Rai, S. Ryzhov, Nicklaus P Atria +2 more
2011Disease Models & Mechanisms301 citations Open access
Semantic Scholar
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.
Holger Diez, Andreas Fischer, A. Winkler, Cheng-Jun Hu +3 more
2007Experimental Cell Research228 citations
Semantic Scholar
Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells
Ji-Jun Hao, M. A. Daleo, Clare K. Murphy, Paul B. Yu +5 more
2008PLoS ONE220 citations Open access
Semantic Scholar
Adherent Platelets Recruit and Induce Differentiation of Murine Embryonic Endothelial Progenitor Cells to Mature Endothelial Cells In Vitro
H. Langer, A. May, Karin Daub, U. Heinzmann +8 more
2006Circulation Research208 citations Open access
Semantic Scholar
Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation
Bing-Ruo Wu, Yi-Dong Wang, Wendy Lui, Melissa M Langworthy +4 more
2011Circulation Research167 citations Open access
Semantic Scholar
Thymosin β4 Is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell–Mediated Cardioprotection
R. Hinkel, Chiraz El-Aouni, Tonia Olson, J. Horstkotte +12 more
2008Circulation164 citations Open access
Semantic Scholar
Biologic properties of endothelial progenitor cells and their potential for cell therapy.
P. Young, D. Vaughan, A. Hatzopoulos
2007Progress in cardiovascular diseases142 citations Open access
Semantic Scholar
Stem cell therapy for cardiac repair: benefits and barriers
Steven J Joggerst, A. Hatzopoulos
2009Expert Reviews in Molecular Medicine138 citations Open access
Semantic Scholar
Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium
N. Salomonis, P. Dexheimer, L. Omberg, Robin Schroll +19 more
2016Stem Cell Reports115 citations Open access
Semantic Scholar
Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population
Wen-Der Wang, D. Melville, Mercedes Montero-Balaguer, A. Hatzopoulos +1 more
2011Developmental Biology111 citations Open access
Semantic Scholar
Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis
E. Karantzali, H. Schulz, O. Hummel, N. Hubner +2 more
2008Genome Biology105 citations Open access
Semantic Scholar
Cardiac repair and regeneration: the Rubik’s cube of cell therapy for heart disease
K. Boudoulas, A. Hatzopoulos
2009Disease Models & Mechanisms99 citations Open access
Semantic Scholar
Adriamycin nephropathy: a failure of endothelial progenitor cell-induced repair.
Kaoru Yasuda, H. Park, B. Ratliff, F. Addabbo +3 more
2010American Journal of Pathology92 citations Open access
Semantic Scholar
The Origin of Matrix-Producing Cells that Contribute to Aortic Fibrosis in Hypertension
Jing Wu, K. R. Montaniel, Mohamed A. Saleh, Liang Xiao +8 more
2015HYPERTENSION87 citations Open access
Semantic Scholar
Rationale and Design for TIME: A Phase-II, Randomized, Double-Blind, Placebo-Controlled Pilot Trial Evaluating the Safety and Effect of Timing of Administration of Bone Marrow Mononuclear Cells Following Acute Myocardial Infarction
J. Traverse, T. Henry, D. Vaughan, S. Ellis +21 more
2009American Heart Journal77 citations Open access
Semantic Scholar
The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis
D. Melville, Mercedes Montero-Balaguer, D. Levic, Kevin M. Bradley +3 more
2011Disease Models & Mechanisms71 citations Open access
Semantic Scholar
Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.
Heike Beck, Matthias Semisch, C. Culmsee, N. Plesnila +1 more
2008American Journal of Pathology71 citations Open access
Semantic Scholar
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A
Manolis Gialitakis, A. Kretsovali, Charalampos G Spilianakis, L. Kravariti +4 more
2006Nucleic Acids Research66 citations Open access
Semantic Scholar
Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis
David T. Paik, M. Rai, S. Ryzhov, Lehanna N Sanders +4 more
2015Circulation Research65 citations Open access
Semantic Scholar
The FunGenES Database: A Genomics Resource for Mouse Embryonic Stem Cell Differentiation
H. Schulz, Raivo Kolde, P. Adler, I. Aksoy +31 more
2009PLoS ONE64 citations Open access
Semantic Scholar
Molecular, phenotypic, and sample-associated data to describe pluripotent stem cell lines and derivatives
Kenneth M. Daily, Shan-Nan-Ho J. Sui, L. Schriml, P. Dexheimer +19 more
2017Scientific Data61 citations Open access
Semantic Scholar
LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction.
J. Traverse, T. Henry, D. Vaughan, S. Ellis +22 more
2010Texas Heart Institute Journal61 citations
Semantic Scholar
Adenosine Receptor-Mediated Adhesion of Endothelial Progenitors to Cardiac Microvascular Endothelial Cells
S. Ryzhov, N. V. Solenkova, Anna E. Goldstein, M. Lamparter +8 more
2008Circulation Research59 citations Open access
Semantic Scholar
Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling
Terri T. Ni, Eric J. Rellinger, A. Mukherjee, L. Stephens +8 more
2011Chemistry and Biology57 citations Open access
Semantic Scholar
The TIME Trial - Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis
J. Traverse, T. Henry, C. Pepine, J. Willerson +16 more
2017Circulation Research56 citations Open access
Semantic Scholar
Combinatorial Polymer Electrospun Matrices Promote Physiologically-Relevant Cardiomyogenic Stem Cell Differentiation
M. Gupta, Joel M. Walthall, R. Venkataraman, S. W. Crowder +9 more
2011PLoS ONE56 citations Open access
Semantic Scholar
Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis
B. Fioret, J. Heimfeld, David T. Paik, A. Hatzopoulos
2014Cell Reports55 citations Open access
Semantic Scholar
Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent.
B. Ratliff, T. Ghaly, Philip Brudnicki, Kaoru Yasuda +5 more
2010AJP - Renal Physiology54 citations Open access
Semantic Scholar
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway
V. Tanwar, Jeffery B. Bylund, Jianyong Hu, Jingbo Yan +9 more
2014Stem Cells53 citations Open access
Semantic Scholar
Bone morphogenetic protein signaling in inflammation
David H Wu, A. Hatzopoulos
2019Experimental biology and medicine52 citations Open access
Semantic Scholar
The BMP Antagonist Gremlin 2 Limits Inflammation After Myocardial Infarction
Lehanna N Sanders, J. Schoenhard, Mohamed A. Saleh, A. Mukherjee +8 more
2016Circulation Research49 citations Open access
Semantic Scholar
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm
Iris I. Müller, D. Melville, V. Tanwar, Witold Rybski +8 more
2012Disease Models & Mechanisms49 citations Open access
Semantic Scholar
Cadherin-11 Blockade Reduces Inflammation-driven Fibrotic Remodeling and Improves Outcomes After Myocardial Infarction
A. Schroer, M. Bersi, Cynthia R. Clark, Qin-Kun Zhang +6 more
2019bioRxiv48 citations Open access
Semantic Scholar
Rationale and Design for the Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells for Patients with Chronic Ischemic Heart Disease and Left Ventricular Dysfunction Trial (FOCUS)
J. Willerson, E. Perin, S. Ellis, C. Pepine +22 more
2010American Heart Journal43 citations Open access
Semantic Scholar
Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling after Myocardial Infarction
J. Snider, Lance A. Riley, Noah T. Mallory, M. Bersi +8 more
2021Circulation38 citations Open access
Semantic Scholar
NF κB Activation in Embryonic Endothelial Progenitor Cells Enhances Neovascularization via PSGL‐1 Mediated Recruitment: Novel Role for LL37
A. Pfosser, Chiraz El-Aouni, I. Pfisterer, M. Dietz +11 more
2009Stem Cells38 citations
Semantic Scholar
Platelet-induced differentiation of endothelial progenitor cells.
H. Langer, A. May, D. Vestweber, H. D. de Boer +2 more
2007Seminars in Thrombosis and Hemostasis37 citations
Semantic Scholar
Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases
M. Hammon, M. Herrmann, O. Bleiziffer, G. Pryymachuk +12 more
2011Journal of Cellular and Molecular Medicine36 citations Open access
Semantic Scholar
T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix
O. Bleiziffer, R. Horch, M. Hammon, A. Arkudas +7 more
2008Journal of Cellular and Molecular Medicine35 citations Open access
Semantic Scholar
Continuous Antagonism by Dkk1 Counter Activates Canonical Wnt Signaling and Promotes Cardiomyocyte Differentiation of Embryonic Stem Cells
M. Rai, Joel M. Walthall, Jianyong Hu, A. Hatzopoulos
2012Stem Cells and Development30 citations Open access
Semantic Scholar
Stem Cell Therapy: Pieces of the Puzzle
J. Schoenhard, A. Hatzopoulos
2009Journal of Cardiovascular Translational Research27 citations Open access
Semantic Scholar
Endothelial Progenitor Cells Augment Collateralization and Hemodynamic Rescue in a Model of Chronic Cerebral Ischemia
N. Hecht, U. Schneider, M. Czabanka, M. Vinci +3 more
2014Journal of Cerebral Blood Flow and Metabolism26 citations Open access
Semantic Scholar
Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits
Chitra Basu, Presley L. Cannon, Cassandra P. Awgulewitsch, Cristi L. Galindo +2 more
2024Scientific Reports22 citations Open access
Semantic Scholar
Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2
Jeffery B. Bylund, L. T. Trinh, Cassandra P. Awgulewitsch, David T. Paik +8 more
2017Stem Cells and Development21 citations Open access
Semantic Scholar
Egr-1 Induces DARPP-32 Expression in Striatal Medium Spiny Neurons via a Conserved Intragenic Element
Serene Keilani, Samira Chandwani, G. Dolios, A. Bogush +6 more
2012Journal of Neuroscience21 citations Open access
Semantic Scholar
Neuregulin-1β regulation of embryonic endothelial progenitor cell survival.
R. Safa, Xu-Yang Peng, Laura Pentassuglia, C. Lim +7 more
2011American Journal of Physiology. Heart and Circulatory Physiology21 citations Open access
Semantic Scholar
B‐Raf‐mediated signaling pathway regulates T cell development
Hirotake Tsukamoto, A. Irie, S. Senju, A. Hatzopoulos +2 more
2008European Journal of Immunology19 citations Open access
Semantic Scholar

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