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C. C. Porter · SciRah

Researcher profile · Semantic Scholar

C. C. Porter

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C. C. Porter — researcher profile on SciRah

h-index: 26
Works: 98
Citations: 2,887

Most-cited papers

Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia
L. Noetzli, Richard W. Lo, A. Lee-Sherick, M. Callaghan +24 more
2015Nature Genetics296 citations Open access
Semantic Scholar
STAT3-Mediated Autophagy Dependence Identifies Subtypes of Breast Cancer where Autophagy Inhibition can be Efficacious
P. Maycotte, Christy M. Gearheart, Rebecca A. Barnard, Suraj Aryal +7 more
2014Cancer Research176 citations Open access
Semantic Scholar
Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma
J. Kalish, L. Doros, L. Helman, R. Hennekam +12 more
2017Clinical Cancer Research172 citations Open access
Semantic Scholar
Irradiation Selects for p53-Deficient Hematopoietic Progenitors
Andriy Marusyk, C. C. Porter, Vadym Zaberezhnyy, J. DeGregori
2010PLoS Biology151 citations Open access
Semantic Scholar
Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition
Matias Casás-Selves, Jihye Kim, Zhi-Yong Zhang, B. Helfrich +7 more
2012Cancer Research136 citations Open access
Semantic Scholar
ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
Xi Luo, Simone K Feurstein, S. Mohan, C. C. Porter +30 more
2019Blood Advances129 citations Open access
Semantic Scholar
Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome
Katherine A. Waugh, Paula Araya, A. Pandey, Kimberly R. Jordan +19 more
2019Cell Reports124 citations Open access
Semantic Scholar
Inhibition of Wee1 sensitizes cancer cells to anti-metabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality
A. V. van Linden, Dmitry Baturin, James B. Ford, S. Fosmire +4 more
2013Molecular Cancer Therapeutics121 citations Open access
Semantic Scholar
MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
Courtney L. Jones, Christy M. Gearheart, S. Fosmire, C. Delgado-Martín +23 more
2015Blood110 citations Open access
Semantic Scholar
Recommendations for Childhood Cancer Screening and Surveillance in DNA Repair Disorders
M. Walsh, Vivian Y. Chang, W. Kohlmann, H. Scott +8 more
2017Clinical Cancer Research104 citations Open access
Semantic Scholar
Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions
C. C. Porter, T. Druley, A. Erez, R. Kuiper +8 more
2017Clinical Cancer Research93 citations Open access
Semantic Scholar
Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and novel therapeutic target in acute myeloid leukemia
C. C. Porter, Jihye Kim, S. Fosmire, Christy M. Gearheart +7 more
2012Leukemia79 citations Open access
Semantic Scholar
ATM and MET kinases are synthetic lethal with non-genotoxic activation of p53
Kelly D. Sullivan, Nuria Padilla-Just, R. Henry, C. C. Porter +6 more
2012Nature Chemical Biology74 citations Open access
Semantic Scholar
ETV6-Related Thrombocytopenia and Leukemia Predisposition.
J. Di Paola, C. C. Porter
2019Blood72 citations Open access
Semantic Scholar
Solution Characterization of the Extracellular Region of CD147 and Its Interaction with Its Enzyme Ligand Cyclophilin A
J. Schlegel, J. Redzic, C. C. Porter, V. Yurchenko +8 more
2009Journal of Molecular Biology72 citations Open access
Semantic Scholar
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia
Hope L. Mumme, Beena E. Thomas, Swati S. Bhasin, Upaasana Krishnan +15 more
2021Nature Communications66 citations Open access
Semantic Scholar
A small molecule inhibitor of WEE1, AZD1775, synergizes with olaparib by impairing homologous recombination and enhancing DNA damage and apoptosis in acute leukemia
Tamara B. Garcia, Jonathan C. Snedeker, Dmitry Baturin, L. Gardner +6 more
2017Molecular Cancer Therapeutics65 citations Open access
Semantic Scholar
Immune responses to influenza immunization in children receiving maintenance chemotherapy for acute lymphoblastic leukemia
C. C. Porter, K. Edwards, Yuwei Zhu, H. Frangoul
2004Pediatric Blood & Cancer65 citations
Semantic Scholar
Impaired DNA Replication within Progenitor Cell Pools Promotes Leukemogenesis
G. Bilousova, Andriy Marusyk, C. C. Porter, R. Cardiff +1 more
2005PLoS Biology60 citations Open access
Semantic Scholar
Germ line mutations associated with leukemias.
C. C. Porter
2016Hematology. American Society of Hematology. Education Program50 citations Open access
Semantic Scholar
Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia
Miyoung Lee, Jamie A. G. Hamilton, G. Talekar, Anthony J. Ross +10 more
2022Nature Communications42 citations Open access
Semantic Scholar
TARGETING DEVELOPMENTAL PATHWAYS IN CHILDREN WITH CANCER: WHAT PRICE SUCCESS?
L. Gore, J. DeGregori, C. C. Porter
2013The Lancet Oncology40 citations Open access
Semantic Scholar
Vincristine induced peripheral neuropathy potentiated by voriconazole in a patient with previously undiagnosed CMT1X
C. C. Porter, A. Carver, Edythe A. Albano
2009Pediatric Blood & Cancer40 citations
Semantic Scholar
Influenza Immunization Practices Among Pediatric Oncologists
C. C. Porter, K. Poehling, R. Hamilton, H. Frangoul +1 more
2003Journal of pediatric hematology/oncology38 citations
Semantic Scholar
Engineered Cytokines for Cancer and Autoimmune Disease Immunotherapy
Biaggio Uricoli, Lacey A Birnbaum, Priscilla Do, J. Kelvin +6 more
2021Advanced Healthcare Materials37 citations Open access
Semantic Scholar
Interleukin‐37 improves T‐cell‐mediated immunity and chimeric antigen receptor T‐cell therapy in aged backgrounds
Jamie A. G. Hamilton, Miyoung Lee, Rae Hunter, Raira S. Ank +11 more
2021Aging Cell31 citations Open access
Semantic Scholar
Stopping Leukemia in Its Tracks: Should Preemptive Hematopoietic Stem-Cell Transplantation be Offered to Patients at Increased Genetic Risk for Acute Myeloid Leukemia?
Kayla V Hamilton, Luke D. Maese, Jonathan M Marron, M. Pulsipher +2 more
2019Journal of Clinical Oncology25 citations
Semantic Scholar
Small Molecule Therapeutics Inhibition of Wee 1 Sensitizes Cancer Cells to Antimetabolite Chemotherapeutics In Vitro and In Vivo , Independent of p 53 Functionality
A. V. van Linden, Dmitry Baturin, James B. Ford, S. Fosmire +4 more
201324 citations
Semantic Scholar
Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.
C. C. Porter, J. DeGregori
2008Blood22 citations Open access
Semantic Scholar
IFN-γ alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils
Michael A. Ellison, Christy M. Gearheart, C. C. Porter, D. Ambruso
2017PLoS ONE21 citations Open access
Semantic Scholar
Posttransplant Hodgkin lymphoma preceded by polymorphic posttransplant lymphoproliferative disorder: report of a pediatric case and review of the literature.
G. Gheorghe, Edythe A. Albano, C. C. Porter, L. Mcgavran +4 more
2007Journal of pediatric hematology/oncology21 citations
Semantic Scholar
ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes
Marlie H. Fisher, Gregory D. Kirkpatrick, Brett M. Stevens, Courtney L. Jones +11 more
2020JCI Insight20 citations Open access
Semantic Scholar
Macrocytic Anemia In Lesch-Nyhan Disease and its Variants
H. Çakmaklı, R. Torres, A. Menendez, G. Yalcin-Cakmakli +3 more
2018Genetics in Medicine20 citations Open access
Semantic Scholar
Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine
Tamara B. Garcia, S. Fosmire, C. C. Porter
2017Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis20 citations Open access
Semantic Scholar
Increased HDAC Activity and c-MYC Expression Mediate Acquired Resistance to WEE1 Inhibition in Acute Leukemia
Tamara B. Garcia, Rizvan C. Uluisik, A. V. van Linden, Kenneth L. Jones +3 more
2020Frontiers in Oncology18 citations Open access
Semantic Scholar
Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care
R. Summers, S. Castellino, C. C. Porter, T. MacDonald +13 more
2022JCO Precision Oncology15 citations
Semantic Scholar
A genome-wide loss-of-function screen identifies SLC26A2 as a novel mediator of TRAIL resistance
L. Dimberg, C. Towers, K. Behbakht, Taylor J. Hotz +6 more
2017Molecular Cancer Research15 citations Open access
Semantic Scholar
Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1+ leukemia
L. Gardner, Jelena Klawitter, M. Gregory, Vadym Zaberezhnyy +7 more
2014American journal of hematology/oncology15 citations Open access
Semantic Scholar
The relative fitness of hematopoietic progenitors influences leukemia progression
C. C. Porter, Dmitry Baturin, R. Choudhary, James DeGregori
2011Leukemia15 citations Open access
Semantic Scholar
Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors
Chengjing Zhou, Rizvan C. Uluisik, J. Rowley, C. David +11 more
2022Experimental Hematology14 citations Open access
Semantic Scholar
The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change
Eric J. Nehl, S. Heilman, David N. Ku, D. Gottfried +55 more
2021IEEE Open Journal of Engineering in Medicine and Biology14 citations Open access
Semantic Scholar
Germline Genetics and Childhood Cancer: Emerging Cancer Predisposition Syndromes and Psychosocial Impacts
Sarah G. Mitchell, B. Pencheva, C. C. Porter
2019Current Oncology Reports14 citations
Semantic Scholar
INF-γ Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself
Michael A. Ellison, G. Thurman, Christy M. Gearheart, Ryan Seewald +2 more
2015PLoS ONE14 citations Open access
Semantic Scholar
Thrombopoietin-based CAR-T cells demonstrate in vitro and in vivo cytotoxicity to MPL positive acute myelogenous leukemia and hematopoietic stem cells
J. Zoine, C. Prince, Jamie Y. Story, Gianna M. Branella +7 more
2021Gene Therapy13 citations Open access
Semantic Scholar
Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers
Hamid H. Gari, Christy M. Gearheart, S. Fosmire, Gregory D. Degala +8 more
2016OncoTarget12 citations Open access
Semantic Scholar
Knockdown of HPRT for Selection of Genetically Modified Human Hematopoietic Progenitor Cells
R. Choudhary, Dmitry Baturin, S. Fosmire, B. Freed +1 more
2013PLoS ONE12 citations Open access
Semantic Scholar
Mass-cytometry reveals global immune remodeling with multi-lineage hypersensitivity to Type I Interferon in Down syndrome
Katherine A. Waugh, A. Pandey, Kimberly R. Jordan, Keith P. Smith +17 more
2019Journal of Immunology10 citations
Semantic Scholar
Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML
Beena E. Thomas, Pruthvi Perumalla, Swati S. Bhasin, Debasree Sarkar +12 more
20209 citations Open access
Semantic Scholar
IL-12 abrogates calcineurin-dependent immune evasion during leukemia progression
Jennifer L. Rabe, L. Gardner, Rae Hunter, Jairo A. Fonseca +13 more
2019Cancer Research9 citations Open access
Semantic Scholar
YB1 modulates the DNA damage response in medulloblastoma
Leon F. McSwain, Claire E Pillsbury, Ramona Haji-Seyed-Javadi, S. Rath +12 more
2023Scientific Reports8 citations Open access
Semantic Scholar

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