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A. Wilmes · SciRah

Researcher profile · Semantic Scholar

A. Wilmes

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A. Wilmes — researcher profile on SciRah

h-index: 23
Works: 78
Citations: 2,047

Most-cited papers

Dyrk, a Dual Specificity Protein Kinase with Unique Structural Features Whose Activity Is Dependent on Tyrosine Residues between Subdomains VII and VIII (*)
H. Kentrup, W. Becker, J. Heukelbach, A. Wilmes +4 more
1996Journal of Biological Chemistry272 citations Open access
Semantic Scholar
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.
A. Wilmes, A. Limonciel, L. Aschauer, Konrad Moenks +23 more
2013Journal of Proteomics177 citations Open access
Semantic Scholar
The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro.
G. Jenkins, K. Harries, S. Doak, A. Wilmes +3 more
2003Carcinogenesis135 citations
Semantic Scholar
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics.
A. Wilmes, C. Bielow, C. Ranninger, P. Bellwon +12 more
2015Toxicology in Vitro123 citations
Semantic Scholar
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity.
A. Wilmes, D. Crean, Sonia Aydin, W. Pfaller +2 more
2011Toxicology in Vitro86 citations Open access
Semantic Scholar
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes.
A. Limonciel, L. Aschauer, A. Wilmes, Sinikka Prajczer +3 more
2011Toxicology in Vitro83 citations Open access
Semantic Scholar
Delineation of the Key Aspects in the Regulation of Epithelial Monolayer Formation
L. Aschauer, Leonhard N. Gruber, W. Pfaller, A. Limonciel +10 more
2013Molecular and Cellular Biology82 citations Open access
Semantic Scholar
Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.
A. Wilmes, K. Bargh, Colleen Kelly, P. Northcote +1 more
2007Molecular Pharmaceutics77 citations
Semantic Scholar
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study.
L. Aschauer, A. Limonciel, A. Wilmes, S. Stanzel +6 more
2015Toxicology in Vitro64 citations
Semantic Scholar
The Molecular and Cellular Aspects of Arthritis Due to Alphavirus Infections
Nestor E. Rulli, Julian V. Melton, A. Wilmes, G. Ewart +1 more
2007Annals of the New York Academy of Sciences59 citations
Semantic Scholar
Differentiation of human iPSCs into functional podocytes
C. Rauch, E. Feifel, G. Kern, C. Murphy +6 more
2018PLoS ONE51 citations Open access
Semantic Scholar
Ross River virus: molecular and cellular aspects of disease pathogenesis.
Nestor E. Rulli, A. Suhrbier, L. Hueston, M. Heise +6 more
2005Pharmacology and Therapeutics51 citations
Semantic Scholar
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods
Alice Krebs, B. V. van Vugt-Lussenburg, T. Waldmann, Wiebke Albrecht +41 more
2020Archives of Toxicology49 citations Open access
Semantic Scholar
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model
P. Jennings, C. Weiland, A. Limonciel, K. M. Bloch +10 more
2011Archives of Toxicology49 citations
Semantic Scholar
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells
A. Limonciel, A. Wilmes, L. Aschauer, R. Radford +8 more
2012Archives of Toxicology48 citations Open access
Semantic Scholar
Peloruside B, a Potent Antitumor Macrolide from the New Zealand Marine Sponge Mycale hentscheli: Isolation, Structure, Total Synthesis and Bioactivity
A. J. Singh, Chun-Xiao Xu, Xiaoming Xu, L. West +6 more
2010Journal of Organic Chemistry46 citations Open access
Semantic Scholar
Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability
V. Chandrasekaran, G. Carta, Daniel da Costa Pereira, Rajinder Gupta +11 more
2021Scientific Reports43 citations Open access
Semantic Scholar
Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq
A. Limonciel, G. Ates, G. Carta, A. Wilmes +8 more
2018Archives of Toxicology39 citations Open access
Semantic Scholar
Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes
Arun Kanakkanthara, A. Wilmes, A. O'Brate, D. Escuin +9 more
2011Molecular Cancer Therapeutics37 citations Open access
Semantic Scholar
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.
D. Crean, P. Bellwon, L. Aschauer, A. Limonciel +10 more
2015Toxicology in Vitro36 citations
Semantic Scholar
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel.
A. Wilmes, L. Aschauer, A. Limonciel, W. Pfaller +1 more
2014Toxicology and Applied Pharmacology36 citations
Semantic Scholar
Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells
A. Wilmes, David O’Sullivan, Ariane Chan, C. Chandrahasen +4 more
2011Cancer Chemotherapy and Pharmacology32 citations
Semantic Scholar
Interleukin-19 as a translational indicator of renal injury
P. Jennings, D. Crean, L. Aschauer, A. Limonciel +7 more
2014Archives of Toxicology30 citations
Semantic Scholar
Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases
E. Zgheib, A. Limonciel, Xiao-Qi Jiang, A. Wilmes +5 more
2018Frontiers in Genetics23 citations Open access
Semantic Scholar
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
A. Limonciel, Konrad Moenks, S. Stanzel, G. L. Truisi +10 more
2015Toxicology in Vitro23 citations
Semantic Scholar
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages
Kirsten E. Snijders, A. Fehér, Z. Táncos, I. Bock +15 more
2021Archives of Toxicology22 citations Open access
Semantic Scholar
Structure-activity studies of the pelorusides: new congeners and semi-synthetic analogues.
A. J. Singh, Mina Razzak, P. Teesdale-Spittle, T. N. Gaitanos +5 more
2011Organic and biomolecular chemistry21 citations
Semantic Scholar
Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems.
P. Bellwon, G. L. Truisi, F. Bois, A. Wilmes +12 more
2015Toxicology in Vitro20 citations
Semantic Scholar
Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood-brain barrier.
Patricia Bellwon, M. Culot, A. Wilmes, Tobias Schmidt +9 more
2015Toxicology in Vitro19 citations
Semantic Scholar
Temporal transcriptomic alterations of cadmium exposed human iPSC-derived renal proximal tubule-like cells.
Pranika Singh, V. Chandrasekaran, B. Hardy, A. Wilmes +2 more
2021Toxicology in Vitro18 citations Open access
Semantic Scholar
Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.
A. Wilmes, C. Rauch, G. Carta, G. Kern +8 more
2017Toxicology in Vitro17 citations Open access
Semantic Scholar
Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae.
A. Wilmes, Reem Hanna, R. Heathcott, P. Northcote +3 more
2012Gene16 citations
Semantic Scholar
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
C. Nunes, Pranika Singh, Z. Mazidi, C. Murphy +17 more
2022Toxicology in Vitro15 citations Open access
Semantic Scholar
Paclitaxel effects on the proteome of HL-60 promyelocytic leukemic cells: comparison to peloruside A
A. Wilmes, Ariane Chan, P. Rawson, T. Jordan +1 more
2012Investigational new drugs15 citations
Semantic Scholar
Human and rat renal proximal tubule in vitro models for ADME applications
O. Klatt, L. de Brouwer, F. Hendriks, E. Dehne +3 more
2025Archives of Toxicology13 citations Open access
Semantic Scholar
Characterization of Organic Anion and Cation Transport in Three Human Renal Proximal Tubular Epithelial Models
Tamara Meijer, Daniel da Costa Pereira, O. Klatt, J. Buitenhuis +2 more
2024Cells11 citations Open access
Semantic Scholar
Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline*
C. Ranninger, Marc Rurik, A. Limonciel, Silke Ruzek +7 more
2015Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells
A. Wilmes, P. Rawson, Lifeng Peng, D. McLauchlan +3 more
2011Investigational new drugs11 citations
Semantic Scholar
Comparison of human recombinant protein coatings and fibroblast-ECM to Matrigel for induced pluripotent stem cell culture and renal podocyte differentiation.
C. Murphy, E. Naderlinger, Amber Mater, R. Kluin +1 more
2022ALTEX10 citations Open access
Semantic Scholar
A Protocol for One-Step Differentiation of Human Induced Pluripotent Stem Cells into Mature Podocytes.
C. Murphy, E. Feifel, P. Jennings, G. Gstraunthaler +1 more
2019Methods in molecular biology8 citations Open access
Semantic Scholar
Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells.
F. Pistollato, A. Bal-Price, S. Coecke, Surat Parvatam +11 more
2022Reproductive Toxicology7 citations Open access
Semantic Scholar
Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.
G. Stacey, S. Coecke, A. Price, L. Healy +11 more
2016Advances in Experimental Medicine and Biology7 citations Open access
Semantic Scholar
Nrf2 inducibility of aldo-keto reductases.
A. Wilmes, M. Leonard, P. Jennings
2013Toxicology Letters7 citations Open access
Semantic Scholar
Differentiation and Subculturing of Renal Proximal Tubular‐like Cells Derived from Human iPSC
Tamara Meijer, E. Naderlinger, P. Jennings, A. Wilmes
2023Current Protocols6 citations Open access
Semantic Scholar
Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells
P. Jennings, G. Carta, Pranika Singh, Daniel da Costa Pereira +4 more
2022Cell Biology and Toxicology6 citations Open access
Semantic Scholar
Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens
A. Limonciel, S. V. van Breda, Xiao-Qi Jiang, Gregory D. Tredwell +9 more
2018Frontiers in Genetics5 citations Open access
Semantic Scholar
Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening
C. Rauch, P. Jennings, A. Wilmes
20145 citations
Semantic Scholar
Transcriptomic profile of human iPSC-derived podocyte-like cells exposed to a panel of xenobiotics.
C. Murphy, Paul Jennings, A. Wilmes
2024Toxicology in Vitro4 citations Open access
Semantic Scholar
Translational Biomarkers, In Vitro and In Vivo
A. Wilmes, A. Limonciel, M. Leonard, P. Jennings
20144 citations
Semantic Scholar
Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models.
Tamara Meijer, B. ter Braak, L. Loonstra-Wolters, S. Kunnen +10 more
2025Toxicology in Vitro3 citations Open access
Semantic Scholar

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