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C. Margue · SciRah

Researcher profile · Semantic Scholar

C. Margue

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C. Margue — researcher profile on SciRah

h-index: 22
Works: 40
Citations: 2,208

Most-cited papers

Many ways to resistance: How melanoma cells evade targeted therapies.
I. Kozar, C. Margue, Sonja Rothengatter, C. Haan +1 more
2019Biochimica et biophysica acta. Reviews on cancer239 citations Open access
Semantic Scholar
Jaks and cytokine receptors--an intimate relationship.
C. Haan, S. Kreis, C. Margue, I. Behrmann
2006Biochemical Pharmacology232 citations Open access
Semantic Scholar
Integrin αvβ3 expression confers on tumor cells a greater propensity to metastasize to bone
Isabelle Pécheur, O. Peyruchaud, C. Serre, J. Guglielmi +7 more
2002The FASEB Journal218 citations
Semantic Scholar
Signatures of microRNAs and selected microRNA target genes in human melanoma.
D. Philippidou, M. Schmitt, Dirk Moser, C. Margue +6 more
2010Cancer Research216 citations Open access
Semantic Scholar
Complete loss of PTEN expression as a possible early prognostic marker for prostate cancer metastasis
M. Schmitz, Gérard Grignard, C. Margue, Walter Dippel +6 more
2007International Journal of Cancer143 citations Open access
Semantic Scholar
NRAS mutant melanoma: Towards better therapies.
Tijana Randic, I. Kozar, C. Margue, J. Utikal +1 more
2021Cancer Treatment Reviews140 citations Open access
Semantic Scholar
MiRNA-29: a microRNA family with tumor-suppressing and immune-modulating properties.
M. Schmitt, C. Margue, Iris Behrmann, S. Kreis
2013Current molecular medicine130 citations
Semantic Scholar
Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
M. Schmitt, D. Philippidou, S. Reinsbach, C. Margue +4 more
2012Cell Communication and Signaling112 citations Open access
Semantic Scholar
Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR
C. Margue, Michele Bernasconi, F. Barr, B. Schäfer
2000Oncogene112 citations Open access
Semantic Scholar
Comparison of a healthy miRNome with melanoma patient miRNomes: are microRNAs suitable serum biomarkers for cancer?
C. Margue, S. Reinsbach, D. Philippidou, N. Beaume +5 more
2015OncoTarget81 citations Open access
Semantic Scholar
New Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion
C. Margue, D. Philippidou, S. Reinsbach, M. Schmitt +2 more
2013PLoS ONE73 citations Open access
Semantic Scholar
Dual Role of the Jak1 FERM and Kinase Domains in Cytokine Receptor Binding and in Stimulation-Dependent Jak Activation1
S. Haan, C. Margue, Arnaud Engrand, Catherine Rolvering +4 more
2008Journal of Immunology64 citations Open access
Semantic Scholar
Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles
Geoffroy Walbrecq, Odile Lecha, A. Gaigneaux, Miriam R Fougeras +7 more
2020Cancers43 citations Open access
Semantic Scholar
IL-24: a classic cytokine and/or a potential cure for cancer?
Stephanie Kreis, D. Philippidou, C. Margue, Iris Behrmann
2008Journal of Cellular and Molecular Medicine40 citations Open access
Semantic Scholar
Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons”
G. Cesi, Geoffroy Walbrecq, C. Margue, S. Kreis
2016Cell Communication and Signaling39 citations Open access
Semantic Scholar
Recombinant Interleukin-24 Lacks Apoptosis-Inducing Properties in Melanoma Cells
S. Kreis, D. Philippidou, C. Margue, Catherine Rolvering +4 more
2007PLoS ONE36 citations Open access
Semantic Scholar
Inhibition of extracellular vesicle‐derived miR‐146a‐5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes
E. Rigg, Jiwei Wang, Zhiwei Xue, T. Lunavat +16 more
2023Journal of Extracellular Vesicles34 citations Open access
Semantic Scholar
Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
M. Schmitt, D. Philippidou, S. Reinsbach, C. Margue +4 more
2012Cell Communication and Signaling32 citations Open access
Semantic Scholar
Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cells
C. Margue, D. Philippidou, I. Kozar, G. Cesi +5 more
2019Journal of experimental & clinical cancer research : CR30 citations Open access
Semantic Scholar
Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells.
I. Kozar, G. Cesi, C. Margue, D. Philippidou +1 more
2017Biochimica et Biophysica Acta - General Subjects28 citations Open access
Semantic Scholar
The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner
Mathieu Heulot, Nadja Chevalier, J. Puyal, C. Margue +6 more
2016OncoTarget23 citations Open access
Semantic Scholar
Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells
I. Kozar, D. Philippidou, C. Margue, Lauren A. Gay +2 more
2021Cancers22 citations Open access
Semantic Scholar
Distinct Cargos of Small Extracellular Vesicles Derived from Hypoxic Cells and Their Effect on Cancer Cells
Geoffroy Walbrecq, C. Margue, I. Behrmann, S. Kreis
2020International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation*
K. Vanhoorelbeke, S. D. De Meyer, I. Pareyn, C. Melchior +7 more
2009Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Single-cell transcriptomics of NRAS-mutated melanoma transitioning to drug resistance reveals P2RX7 as an indicator of early drug response.
Tijana Randic, S. Magni, D. Philippidou, C. Margue +8 more
2023Cell Reports15 citations Open access
Semantic Scholar
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma
Vincent Gureghian, H. Herbst, I. Kozar, Katarina Mihajlović +18 more
2023bioRxiv15 citations Open access
Semantic Scholar
The PD‐L1‐ and IL6‐mediated dampening of the IL27/STAT1 anticancer responses are prevented by α‐PD‐L1 or α‐IL6 antibodies
Catherine Rolvering, A. Zimmer, A. Ginolhac, C. Margue +10 more
2018Journal of Leukocyte Biology14 citations Open access
Semantic Scholar
ILK as a potential marker gene to ascertain specific adenocarcinoma cell mRNA isolation from frozen prostate biopsy tissue sections.
N. Kieffer, M. Schmitz, S. Plançon, C. Margue +6 more
2005International Journal of Oncology12 citations
Semantic Scholar
Protocol to generate scaffold-free, multicomponent 3D melanoma spheroid models for preclinical drug testing
C. Angeli, Joanna Patrycja Wróblewska, Eliane Klein, C. Margue +1 more
2024STAR Protocols9 citations Open access
Semantic Scholar
Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma
Tamara Bintener, Maria Pires Pacheco, D. Philippidou, C. Margue +10 more
2023Cell Death and Disease7 citations Open access
Semantic Scholar
High-throughput drug screening in advanced pre-clinical 3D melanoma models identifies potential first-line therapies for NRAS-mutated melanoma
C. Angeli, D. Philippidou, Eliane Klein, C. Margue +9 more
2025Journal of experimental & clinical cancer research : CR6 citations Open access
Semantic Scholar
Systematic Transcriptional Profiling of Responses to STAT1- and STAT3-Activating Cytokines in Different Cancer Types.
M. Kirchmeyer, Florence A. Servais, A. Ginolhac, P. Nazarov +6 more
2020Journal of Molecular Biology5 citations Open access
Semantic Scholar
Circulating microRNAs as Candidate Biomarkers for the Surveillance of Melanoma Patients
I. Behrmann, C. Margue, S. Kreis
2015EBioMedicine3 citations Open access
Semantic Scholar
Single-Cell Transcriptomics of Distinct Cell States in NRAS-Mutated Melanoma Transitioning to Drug Resistance: Elevated P2RX7 Levels Indicate Response to Targeted Therapy
Tijana Randic, S. Magni, D. Philippidou, K. Grzyb +7 more
2022Social Science Research Network2 citations Open access
Semantic Scholar
TMIC-47. INHIBITION OF MIR-146A-5P DECREASES PROGRESSION OF MELANOMA BRAIN METASTASIS VIA NOTCH PATHWAY DYSREGULATION IN ASTROCYTES
E. Rigg, Jiwei Wang, Zhiwei Xue, T. Lunavat +16 more
2023Neuro-Oncology0 citations Open access
Semantic Scholar
Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons”
G. Cesi, Geoffroy Walbrecq, C. Margue, S. Kreis
2016Cell Communication and Signaling0 citations Open access
Semantic Scholar
in Stimulation-Dependent Jak Activation Domains in Cytokine Receptor Binding and Dual Role of the Jak1 FERM and Kinase
I. Behrmann, C. Rolvering, C. Margue, Arnaud Engrand
20140 citations
Semantic Scholar
The Novel S527F Mutation in the Integrin 3 Chain Induces a High Affinity IIb3 Receptor by Hindering Adoption of the
K. Vanhoorelbeke, S. Meyer, I. Pareyn, C. Melchior +6 more
20090 citations
Semantic Scholar
The anti-apoptotic function of paired box transcription factors
C. Margue
20000 citations
Semantic Scholar
A case control study of cigarette smoking and lung cancer in Luxembourg.
G. Mahon, M. Dicato, F. Ries, R. Muller +4 more
1990Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg0 citations
Semantic Scholar

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