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N. Raffaelli · SciRah

Researcher profile · Semantic Scholar

N. Raffaelli

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N. Raffaelli — researcher profile on SciRah

h-index: 44
Works: 134
Citations: 5,567

Most-cited papers

De novo NAD+ synthesis enhances mitochondrial function and improves health
E. Katsyuba, Adrienne Mottis, Marika Ziętak, F. De Franco +15 more
2018Nature398 citations Open access
Semantic Scholar
Enzymology of NAD+ homeostasis in man
G. Magni, A. Amici, Monica Emanuelli, G. Orsomando +2 more
2003Cellular and Molecular Life Sciences (CMLS)282 citations Open access
Semantic Scholar
Enzymology of NAD+ synthesis.
G. Magni, A. Amici, M. Emanuelli, N. Raffaelli +1 more
1999Advances in Enzymology and Related Subjects255 citations
Semantic Scholar
Bread enriched with cricket powder (Acheta domesticus): A technological, microbiological and nutritional evaluation
A. Osimani, V. Milanović, Federica Cardinali, Andrea Roncolini +8 more
2018Innovative Food Science & Emerging Technologies249 citations Open access
Semantic Scholar
Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia.
V. Audrito, Sara Serra, D. Brusa, F. Mazzola +13 more
2015Blood191 citations Open access
Semantic Scholar
Molecular Cloning, Chromosomal Localization, Tissue mRNA Levels, Bacterial Expression, and Enzymatic Properties of Human NMN Adenylyltransferase*
M. Emanuelli, F. Carnevali, F. Saccucci, F. Pierella +3 more
2001Journal of Biological Chemistry189 citations Open access
Semantic Scholar
Protein fortification with mealworm (Tenebrio molitor L.) powder: Effect on textural, microbiological, nutritional and sensory features of bread
Andrea Roncolini, V. Milanović, Federica Cardinali, A. Osimani +13 more
2019PLoS ONE178 citations Open access
Semantic Scholar
Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues
V. Mori, A. Amici, F. Mazzola, M. Di Stefano +5 more
2014PLoS ONE169 citations Open access
Semantic Scholar
Insight into the proximate composition and microbial diversity of edible insects marketed in the European Union
A. Osimani, C. Garofalo, V. Milanović, M. Taccari +9 more
2017European Food Research and Technology165 citations
Semantic Scholar
CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells*
Alessia Grozio, Giovanna Sociali, L. Sturla, I. Caffa +6 more
2013Journal of Biological Chemistry147 citations Open access
Semantic Scholar
Identification of a novel human nicotinamide mononucleotide adenylyltransferase.
N. Raffaelli, L. Sorci, A. Amici, M. Emanuelli +2 more
2002Biochemical and Biophysical Research Communications - BBRC133 citations
Semantic Scholar
Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors
Davide Antoniani, Paola Bocci, A. Maciąg, N. Raffaelli +1 more
2009Applied Microbiology and Biotechnology131 citations
Semantic Scholar
Addition of Olive Pomace to Feeding Substrate Affects Growth Performance and Nutritional Value of Mealworm (Tenebrio Molitor L.) Larvae
S. Ruschioni, N. Loreto, R. Foligni, C. Mannozzi +10 more
2020Foods109 citations Open access
Semantic Scholar
NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.
M. Di Stefano, A. Loreto, G. Orsomando, V. Mori +9 more
2017Current Biology97 citations Open access
Semantic Scholar
The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes
Jessica L Kostick, Lee T. Szkotnicki, E. A. Rogers, Paola Bocci +2 more
2011Molecular Microbiology93 citations Open access
Semantic Scholar
Phytotoxic Protein PcF, Purification, Characterization, and cDNA Sequencing of a Novel Hydroxyproline-containing Factor Secreted by the Strawberry Pathogen Phytophthora cactorum *
G. Orsomando, M. Lorenzi, N. Raffaelli, Marco Dalla Rizza +2 more
2001Journal of Biological Chemistry89 citations Open access
Semantic Scholar
The Escherichia coli NadR Regulator Is Endowed with Nicotinamide Mononucleotide Adenylyltransferase Activity
N. Raffaelli, T. Lorenzi, P. Mariani, M. Emanuelli +3 more
1999Journal of Bacteriology89 citations Open access
Semantic Scholar
Transcriptional regulation of NAD metabolism in bacteria: NrtR family of Nudix-related regulators
D. Rodionov, J. De Ingeniis, C. Mancini, Flavio Cimadamore +3 more
2008Nucleic Acids Research86 citations Open access
Semantic Scholar
Structure of nicotinamide mononucleotide adenylyltransferase: a key enzyme in NAD(+) biosynthesis.
I. D'Angelo, N. Raffaelli, V. Dabusti, T. Lorenzi +2 more
2000Structure79 citations Open access
Semantic Scholar
Tissue expression and biochemical characterization of human 2‐amino 3‐carboxymuconate 6‐semialdehyde decarboxylase, a key enzyme in tryptophan catabolism
L. Pucci, S. Perozzi, Flavio Cimadamore, G. Orsomando +1 more
2007The FEBS Journal74 citations
Semantic Scholar
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
Antonella Managò, V. Audrito, F. Mazzola, L. Sorci +13 more
2019Nature Communications70 citations Open access
Semantic Scholar
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues.
S. Ruggieri, G. Orsomando, L. Sorci, N. Raffaelli
2015Biochimica et Biophysica Acta70 citations Open access
Semantic Scholar
Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model
Giovanna Sociali, Lizzia Raffaghello, Mirko Magnone, Federica Zamporlini +8 more
2015OncoTarget69 citations Open access
Semantic Scholar
Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites.
Daniela Buonvicino, F. Mazzola, Federica Zamporlini, F. Resta +12 more
2018Cell Chemical Biology68 citations Open access
Semantic Scholar
Identification of Nicotinamide Mononucleotide Deamidase of the Bacterial Pyridine Nucleotide Cycle Reveals a Novel Broadly Conserved Amidohydrolase Family*
Luca Galeazzi, Paola Bocci, A. Amici, L. Brunetti +7 more
2011Journal of Biological Chemistry66 citations Open access
Semantic Scholar
SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells
Giovanna Sociali, Alessia Grozio, I. Caffa, Susanne Schuster +12 more
2018The FASEB Journal62 citations Open access
Semantic Scholar
Pichia anomala DBVPG 3003 Secretes a Ubiquitin-Like Protein That Has Antimicrobial Activity
J. De Ingeniis, N. Raffaelli, M. Ciani, I. Mannazzu
2008Applied and Environmental Microbiology62 citations Open access
Semantic Scholar
Identification and characterization of YLR328W, the Saccharomyces cerevisiae structural gene encoding NMN adenylyltransferase. Expression and characterization of the recombinant enzyme
M. Emanuelli, F. Carnevali, M. Lorenzi, N. Raffaelli +3 more
1999FEBS Letters60 citations Open access
Semantic Scholar
NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer
V. Audrito, Antonella Managò, Federica Gaudino, L. Sorci +3 more
2019Frontiers in Immunology59 citations Open access
Semantic Scholar
Structure and function of nicotinamide mononucleotide adenylyltransferase.
G. Magni, A. Amici, M. Emanuelli, G. Orsomando +2 more
2004Current Medicinal Chemistry59 citations
Semantic Scholar
Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis.
N. Raffaelli, L. Finaurini, F. Mazzola, L. Pucci +3 more
2004Biochemistry56 citations
Semantic Scholar
Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay.
S. Ummarino, M. Mozzon, Federica Zamporlini, A. Amici +4 more
2017Food Chemistry53 citations Open access
Semantic Scholar
Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma
V. Audrito, Antonella Managò, Sofia La Vecchia, Federica Zamporlini +12 more
2018Journal of the National Cancer Institute52 citations Open access
Semantic Scholar
A Novel Fold Revealed by Mycobacterium tuberculosis NAD Kinase, a Key Allosteric Enzyme in NADP Biosynthesis*
S. Garavaglia, N. Raffaelli, L. Finaurini, G. Magni +1 more
2004Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+ biosynthetic machinery in mammalian cells
Federica Zamporlini, S. Ruggieri, F. Mazzola, A. Amici +2 more
2014The FEBS Journal49 citations Open access
Semantic Scholar
The diguanylate cyclase YddV controls production of the exopolysaccharide poly-N-acetylglucosamine (PNAG) through regulation of the PNAG biosynthetic pgaABCD operon.
L. Tagliabue, Davide Antoniani, A. Maciąg, Paola Bocci +2 more
2010Microbiology49 citations
Semantic Scholar
Structure and function of an ADP-ribose dependent transcriptional regulator of NAD metabolism
N. Huang, J. De Ingeniis, Luca Galeazzi, C. Mancini +6 more
2009Structure49 citations Open access
Semantic Scholar
NAD(P) biosynthesis enzymes as potential targets for selective drug design.
G. Magni, M. Di Stefano, G. Orsomando, N. Raffaelli +1 more
2009Current Medicinal Chemistry48 citations
Semantic Scholar
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA
Natthakan Thongon, C. Zucal, V. D'Agostino, T. Tebaldi +9 more
2018Cancer & Metabolism44 citations Open access
Semantic Scholar
Structural and functional properties of NAD kinase, a key enzyme in NADP biosynthesis.
G. Magni, G. Orsomando, N. Raffaelli
2006Mini-Reviews in Medical Chemistry44 citations
Semantic Scholar
Synechocystis sp. slr0787 protein is a novel bifunctional enzyme endowed with both nicotinamide mononucleotide adenylyltransferase and ‘Nudix' hydrolase activities
N. Raffaelli, T. Lorenzi, A. Amici, M. Emanuelli +2 more
1999FEBS Letters44 citations
Semantic Scholar
Genomics-driven Reconstruction of Acinetobacter NAD Metabolism
L. Sorci, I. Blaby, J. De Ingeniis, S. Gerdes +3 more
2010Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.
M. Emanuelli, A. Amici, F. Carnevali, F. Pierella +2 more
2003Protein Expression and Purification41 citations
Semantic Scholar
Enzymology of extracellular NAD metabolism
Massimiliano Gasparrini, L. Sorci, N. Raffaelli
2021Cellular and Molecular Life Sciences37 citations Open access
Semantic Scholar
α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD+) Biosynthesis.
R. Pellicciari, P. Liscio, N. Giacchè, F. De Franco +6 more
2018Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Impact of thistle rennet from Carlina acanthifolia All. subsp. acanthifolia on bacterial diversity and dynamics of a specialty Italian raw ewes' milk cheese.
Federica Cardinali, A. Osimani, M. Taccari, V. Milanović +10 more
2017Journal of food microbiology36 citations Open access
Semantic Scholar
Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism.
N. Huang, L. Sorci, Xuejun Zhang, C. Brautigam +6 more
2008Structure36 citations Open access
Semantic Scholar
Human erythrocyte pyrimidine 5-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to alpha-interferon.
A. Amici, Monica Emanuelli, N. Raffaelli, S. Ruggieri +2 more
2000Blood32 citations
Semantic Scholar
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma
V. Audrito, Antonella Managò, Federica Zamporlini, E. Rulli +9 more
2018OncoTarget30 citations Open access
Semantic Scholar
Yeast and mould dynamics in Caciofiore della Sibilla cheese coagulated with an aqueous extract of Carlina acanthifolia All.
Federica Cardinali, M. Taccari, V. Milanović, A. Osimani +8 more
2016Yeast30 citations Open access
Semantic Scholar

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